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1325 articles for “limitations”
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A New Separation Technique for Method, Development and Validation of Aclidinium Bromide and Formoterol Fumarate in Its Pure and Pharmaceutical Dosage Form by Using Rp-HPLC
Abstract: A new simple, precise, selective and accurate, a new method of development and validation using Rp-HPLC for the estimation of Aclidinium bromide and Formoterol Fumarate in its pure and pharmaceutical dosage form. Chromatogram was run through DIKMA Spursil, C18 segment (4.6×150 mm, 5µ0). Mobile phases contain 0.1% OPA: Acetonitrile (30:70) with the use of the 0.1% OPA buffer, stream rate of 1 ml/min and measured in 280 nm. The run …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 18–36 Read article
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In-silico Approach of Few Selected Phytoconstituents on Newer Cancer Targets
Abstract: Background: Cancer’s high death rates are mainly due to, drug resistance and unmet medical demands. It necessitates novel anticancer medications. AI tools aid in efficient and faster drug discovery by analyzing data, modeling processes and optimizing pipeline stages. Aim: The aim of this present study is to evaluate phytoconstituents against novel and newer cancer targets. Methodology: The ligands Daidzein, Resveratrol and Genistein were targeted against the Glutamate dehydrogenase (PDB ID …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 12–17 Read article
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Identifying and Mitigating Chemical Hazards Through Hazard Identification and Risk Assessment Using Failure Mode and Effects Analysis (FMEA)
Abstract: Chemical exposure represents a significant occupational health and safety concern in the chemical industry. Effectively addressing these hazards requires teamwork among various occupational health and safety experts, such as general OHS professionals, occupational hygienists, and occupational health practitioners. This research focuses on analyzing hazards and developing control measures for industrial chemicals, evaluating their toxicity, and using these assessments in regulatory decision making. It starts by addressing the availability of toxicological …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 1, 2024 · pp. 52–62 Read article
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Nanotechnology in Context of Environment and Industrial Development: A Review
Abstract: Climate change and sustainable development with context to environment has been one of the main concerns and challenges of 21st century. Industrialization and development go hand in hand, so we need to devise green synthetic routes so that our environment stays protected. In the past two decades, there has been significant advancement in the field of nanotechnology. Many cost-effective methods have been devised for large-scale production. Significant improvements have been …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 2, 2024 · pp. 7–14 Read article
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Study of High-rise Building with Varying Imposed Loads Condition for Lateral Load Excitation
Abstract: The demand for land has risen, causing scarcity and leading to a significant increase in the construction of tall residential and commercial buildings. With limited land and a growing population, expanding horizontally is not feasible, making multistory buildings the solution. Urbanization has led to the construction of numerous high-rise structures, emphasizing the need for a thorough understanding and analysis of these structures. The present study aims to determine the critical …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 2, 2024 · pp. 92–106 Read article
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In-depth Evaluation of the CBR Method in Flexible Pavement Design
Abstract: The California Bearing Ratio (CBR) value of the subgrade is a crucial parameter utilized in the design of flexible pavements, as recommended by the Indian Roads Congress (IRC). The choice of materials used in constructing the pavement can significantly influence its overall design and performance. Pavements play an essential role in ensuring traffic flows smoothly, safely, and efficiently. Generally, pavements are categorized into two types: flexible and rigid. Flexible pavements …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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3D Printing for Polymer Science Visualization
Abstract: The burgeoning field of 3D printing offers exciting possibilities for various scientific disciplines. This paper explores the potential integration of 3D printing technology within the realm of polymer analysis. While the core focus of memory forensics investigations lies in digital forensics, the concept of 3D printing complex data structures presents intriguing possibilities for the visualization and communication of findings in polymer science. Here, we propose a future research avenue where …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 96–101 Read article
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Experimental Research on the Strength Properties of Concrete with Recycled Aggregate, Pond Ash, and Rubber Powder Replaced in Part for Concrete Materials in Standard Grades
Abstract: Concrete, a fundamental material in modern construction, poses environmental concerns due to its significant carbon footprint. To mitigate this impact, researchers explore alternative materials like fly ash, GGBS, alcofine, and rubber powder as cement replacements. This study examines the durability and strength of concrete that contains recycled aggregate, pond ash, and waste rubber powder. Waste rubber, abundant from industrial and automotive sources, poses disposal challenges. Pond ash, a byproduct of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 11–21 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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Autism Spectrum Disorder Prediction Using Classification Techniques: A Comparative Analysis
Abstract: Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder marked by difficulties in social interaction, communication, and repetitive behaviors. Identifying and addressing ASD early is essential for enhancing the quality of life for those affected. Data mining techniques have emerged as powerful tools in analyzing large datasets to predict and diagnose ASD, aiding in early identification and intervention. This article presents a comprehensive comparative analysis of classification techniques employed in …
Published in Journal of Computer Technology & Applications · Vol. 15, Issue 3, 2024 · pp. 66–71 Read article
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An Analysis of Multimodal Fusion in Deepfake Detection for Video Samples
Abstract: In today’s rapidly evolving digital landscape, deepfake technology stands as both a marvel and a threat to privacy and security. Deepfakes, hyper-realistic synthetic media created using artificial intelligence (AI), can deceive and manipulate on an unprecedented scale, from political propaganda to compromising videos of public figures. This research navigates deepfake detection, focusing on two advanced methodologies: the vision transformers (ViT) image classifier and the Meso4 method. The ViT model utilizes …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 11, Issue 3, 2024 · pp. 19–27 Read article
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Digital Voting System Using Blockchain
Abstract: The advent of blockchain technology has ushered in a new era of secure, transparent, and decentralized systems, providing a promising foundation for various applications, including electronic voting (e-voting). This report examines the development and deployment of a blockchain-based e-voting system designed to tackle the ongoing issues of security, transparency, and voter privacy in elections. The system utilizes blockchain's core features, including immutability, decentralization, and cryptographic security, to establish a secure …
Published in Journal of Web Engineering & Technology · Vol. 11, Issue 3, 2024 · pp. 8–14 Read article
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E-Commerce Bike Selling Website
Abstract: “RideXpert”, a selling website, is an online platform designed to facilitate the buying and selling of bicycles. Its purpose is to connect sellers and buyers conveniently and efficiently, eliminating geographical limitations and allowing for a broader market reach. These websites typically feature a diverse range of bicycles, catering to various preferences and needs, including road bikes, mountain bikes, hybrids, and more. To facilitate the purchasers many useful features have been …
Published in Journal of Web Engineering & Technology · Vol. 11, Issue 3, 2024 · pp. 15–21 Read article
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Decoding Big Data: A Practical Comparison Between Hadoop and Spark
Abstract: This paper conducts a comprehensive comparison of Apache Hadoop and Apache Spark, two essential frameworks in the big data era. The rapid expansion of data possesses challenges in terms of volume, variety, and velocity, which necessitate advanced processing solutions. Hadoop, utilizing its MapReduce paradigm, provides scalable and fault-tolerant storage, whereas Spark, built upon Hadoop, introduces in-memory processing to increase speed and flexibility. This study includes a detailed examination of their …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 3, 2024 · pp. 15–23 Read article
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To Investigate Hormonal Fluctuations in Male Rattus norvegicus after Treatment with 50% Methanolic Extract of Acacia arabica
Abstract: The use of medicinal plants in traditional and modern medicine has garnered significant interest for their therapeutic potential. Acacia arabica, commonly known as babul, is renowned for its bioactive compounds and diverse pharmacological properties. This study investigates the hormonal fluctuations induced by 50% methanolic extract of Acacia arabica in male Rattus norvegicus, aiming to explore its potential as a male contraceptive. Male contraception remains limited primarily to condoms and vasectomy, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 28–38 Read article
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Enhancing Upper Limb Rehabilitation: Workspace, Singularity and Structural Analysis of an Adaptive Two-Link Planar Manipulator
Abstract: The current shortage of therapists and caregivers who assist individuals with physical disabilities at home is anticipated to worsen in the future. Rehabilitation for upper limb exercises conducted by physical therapists is both time-consuming and expensive. This paper introduces a lightweight two-link planar device with revolute joints designed for upper limb rehabilitation. The primary focus is on the end-effector setup, evaluating its potential to enhance rehabilitation techniques. The manipulator's design …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 162–174 Read article
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Evaluating Diagrid Systems: A Modern Approach to Lateral Load Resistance Across Varied Building Heights
Abstract: Modern architectural design and engineering often incorporate advanced structural systems, with diagrid structures becoming popular for high-rise buildings due to their unique geometric patterns and aesthetic appeal. Despite considerable global research on diagrids, a detailed comparative analysis of their structural efficiency remains limited. This thesis assesses the structural efficiency and seismic performance of diagrid lateral load-resisting systems. The effectiveness of diagrids was compared to conventional building designs in multi-storey buildings …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 1–12 Read article
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Automatic Power Switching Mains for Various Sources
Abstract: This project's major objective is to autonomously choose from four possible power sources—mains, generator, inverter, and solar—to guarantee a load's continuous power delivery. This is crucial due to the rising demand for electricity and the frequent power disruptions affecting industries, hospitals, and households. Establishing an alternative power source is imperative to address this issue. In this project, four switches are utilized to simulate the failure of individual power sources. Pressing …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 2, 2023 · pp. 24–30 Read article
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The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
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Biokinetics of Retention and Dose Delivery to Body Organs due to Protracted Ingestion of Natural Uranium in Groundwater of Patiala District, Punjab, India
Abstract: This study pertains to the uranium concentration in the drinking water and its biokinetics of the retention and dose delivered to body organs of the residents of 50 villages of the Patiala district of the Punjab State where U content is higher than the safe limit of 30 ppb fixed by WHO. U content values vary from 38.0 µg/L (Uppli) to 267.0 µg/L (Ahru Kalan) with an average value of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 1–15 Read article