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136 articles for “treatment-resistant”
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Understanding Tennis Elbow: Causes, Symptoms, and Available Treatments
Abstract: Tennis Elbow, clinically termed lateral epicondylitis, stands as a prevalent musculoskeletal ailment affecting the outer part of the elbow. Despite its name, this condition isn't exclusive to tennis players; it often arises due to repetitive stress or overuse of the forearm muscles and tendons, leading to micro-tears and inflammation at the elbow's lateral epicondyle. The abstract focuses on elucidating the multifaceted aspects of Tennis Elbow, exploring its causes, symptoms, and …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Patient Profile and Antimicrobial Susceptibility Testing of Clinically Isolates In E. coli
Abstract: Escherichia coli, commonly known as E. coli, is a prevalent bacterium capable of causing infections in humans. The development of antimicrobial resistance in E. coli poses a significant public health issue. This study aimed to determine the patient profile and antimicrobial susceptibility patterns of clinically isolated E. coli. A retrospective study was carried out on E. coli samples collected from clinical specimens within a hospital environment. Patient profiles, including age, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 32–47 Read article
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Enhancing Machinability in the Heat Treatment of Inconel 718: A Comprehensive Review
Abstract: The increasing need for materials with high strength and heat resistance, particularly in aerospace applications, creates machining issues. These materials are generally difficult to machine because to their strong wear resistance, abrasion resistance, and low heat conductivity. This produces strong cutting forces and temperatures, resulting in a limited tool life. variances in the microstructures of various materials can induce variations in machinability due to variances in chemical composition, casting, forging …
Published in International Journal of Energy and Thermal Applications · Vol. 2, Issue 1, 2024 · pp. 9–20 Read article
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Bacterial Spectral in UTI in a Hospital Environment
Abstract: Urinary tract infections (UTIs) represent a significant public health issue, primarily caused by a variety of pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. UTIs contribute substantially to illness and complications in individuals with pre-existing health conditions and account for a large portion of hospital visits globally. UTIs are usually self-limiting in people with no structural or functional problems, but they do tend to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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Revolutionizing Blood Cancer Treatment: Emerging Therapies and Future Perspectives
Abstract: Blood cancer inclusive of leukemia, lymphoma and multiple myeloma poses a significant threat in the world today because of its multifactorial process and its non-amenable to standard therapies. Some of such approaches are immunotherapy, gene-editing technology and targeted small molecule inhibitors that have altered the nature of treatments. CAR T cell therapy is a molecular targeted therapy for cancers and several clinical studies have reported a huge success. Also, the …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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Exploring Emerging Water Disinfection Technologies: A focus on Hydrodynamic Cavitation
Abstract: Availability of clean drinking water is an ongoing global demand. Contaminated water sources, inappropriate waste disposal, and inadequate hygiene procedures exacerbate it. These elements support the growth of pathogenic microbes like bacteria, viruses, and parasites, which cause a variety of diseases that are transmitted by water. Disinfection plays a vital role in water treatment processes by eliminating these pathogens and ensuring public health safety. Commonly used methods like Chlorination, Ozonation, …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 44–53 Read article
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Comprehensive Strategies for the Prevention and Management of Genital Thrush in Males and Females: A Public Health Approach in Punjab (September 2024 to February 2025)
Abstract: Background: Genital thrush, a common fungal infection caused mainly by Candida albicans, affected both men and women, leading to itching, discomfort, and recurrent infections. In Punjab, high humidity, poor hygiene awareness, excessive antibiotic use, and limited access to healthcare contributed to its widespread occurrence. Without effective prevention and management strategies, the condition significantly impacted quality of life. Addressing this issue through a public health approach was essential for reducing its …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
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Post-Treatment Methods in Additive Manufacturing: A Review of Mechanical, Thermal, Chemical, and Hybrid Approaches
Abstract: Additive manufacturing, particularly Fused Deposition Modeling (FDM), has become a cornerstone of rapid prototyping and functional part production due to its accessibility and material versatility. However, the inherent layer-by-layer nature of FDM introduces surface roughness, reduced mechanical strength, and anisotropic behavior, which limit its industrial applications. This literature review investigates the impact of chemical post-processing treatments such as solvent vapor smoothing, immersion, and hybrid chemical-thermal methods on the surface quality …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 3, 2025 · pp. 25–34 Read article
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Impact of Chemical Conditioning on the Mechanical Performance of Pine Fibre-Reinforced Composites
Abstract: The study examines the effects of treatments like alkaline, silane, and acetylation on enhancing the mechanical strength and reducing water absorption in pine fiber-reinforced composites. Natural fibres, while eco-friendly and sustainable, present challenges in fibre-matrix adhesion due to their hydrophilic nature, impacting composite performance. Chemical treatments were employed to modify fibre surface characteristics, enhance interfacial bonding, and thereby improve mechanical properties. Silane-treated composites exhibited the highest tensile and flexural strengths, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 140–150 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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The Future is Bioengineered: Consequences, Directions, and Regulation
Abstract: Biotechnology is changing how people interact with health, life, and the environment very quickly. This article talks about how new tools in genetic engineering, synthetic biology, and bioinformatics are making it possible for scientists to build and change biological things with more accuracy than ever before. Biotechnology is changing several fields, from making personalised medical treatments and disease-resistant crops to making biofuels and materials that break down naturally. The talk …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Infectious illnesses in areas of violence and among refugees
Abstract: Infectious illnesses are a huge and ongoing hazard in conflict zones and among refugee populations. This is because frail health systems, population relocation, and poor living conditions all come together to make transmission risks higher. Armed conflict undermines vital public health infrastructure, such as vaccination programs, disease surveillance, water and sanitation systems, and access to medical care, resulting in the resurgence and proliferation of avoidable and treatable illnesses. Refugee camps …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 36–40 Read article