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80 articles for “tissue design”
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Predictive Modeling of Polymer Composites for Medical Implants Using Artificial Intelligence Techniques
Abstract: The use of polymers in biomaterials was now key to designing the next generation of medical implants, which need to be strong and also compatible with living tissue. Tests for biocompatibility, such as those done in the laboratory and by doing experiments on animals, require much time and many resources, so the need for computer-based approaches becomes clear. An artificial intelligence approach was provided in this study to determine how …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 665–692 Read article
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Effectiveness of A structured teaching program on Leucorrhoea and it's management for women of Reproductive age group at selected college in Honavar
Abstract: Leucorrhea, also known as leucorrhea, is a white, yellow, or green discharge from a woman's vagina, which may be normal or asign of an infection. Leucorrhea is common during pregnancy and is typically normal if the discharge is thin, white, and odorless.Physiological leucorrhea is a condition that occurs in young women several months to a year after the onset of menstruation. It sometimes occurs in newborn girls and usually lasts …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 40–44 Read article
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Systematic Hydroponic Review and Cultivation Strategies for Bacopa Monnieri
Abstract: Bacopa monnieri (L.) Wettst. (Brahmi; Plantaginaceae) is a medicinally important herb whose nootropic, antioxidant and anti-inflammatory properties derive largely from a group of triterpenoid saponins known as bacosides. Rising global demand for such compounds has made reliable, high-yield production a research priority and has prompted a search for cultivation systems superior to conventional field cultivation. This review compares field cultivation, in vitro micropropagation, bioreactor culture, hydroponics and elicitation for their …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 2, 2026 · pp. 23–28 Read article
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Contribution of Dalak (Massage) in the Treatment of Waja-uz-Zohar (Back Pain): A Review
Abstract: Classical Unani literature presents a detailed understanding of Waja-ul-Mafasil (diseases of bones and joints) among which Waja-uz-Zohar (low back pain) has received extensive attention. Distinguished Unani physicians meticulously described its etiology, clinical features, complications, and treatment modalities. According to Unani theory Waja-uz-Zohar is defined as pain originating from the muscles, ligaments, and connective tissues surrounding the lumbar and lumbosacral regions. Prominent scholars, such as Ibn Sina and Zakariya Razi, attributed …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 1–6 Read article
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Identification and Categorization of Brain Tumors
Abstract: Brain tumors are a serious and aggressive disease that can lead to a reduced life expectancy. Strategic and well-thought-out treatment planning significantly contributes to improving a patient's overall quality of life. Many different imaging techniques, such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and also ultrasound are used to evaluate tumors in different parts of the body, with a focus on using MRI images for brain tumors. It is …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 32–37 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Microneedles: An Innovative Drug Delivery System
Abstract: Microneedles represent a groundbreaking innovation in drug delivery systems, offering a transformative alternative to conventional hypodermic needles and transdermal patches. This advanced technology combines the precision and efficacy of needle-based delivery with the convenience and pain-free nature of patches, creating a minimally invasive platform that addresses many limitations of traditional drug administration. Microneedles are designed to penetrate the stratum corneum – the skin’s outermost layer – without reaching pain-sensitive nerves …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 60–67 Read article
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CHARACTERIZATION, VIRULENCE TESTING AND ANTIFUNGAL SUSCEPTIBILITY PATTERN OF VARIOUS CANDIDA SPECIES AT TERTIARY CARE CENTRE, AMRITSAR
Abstract: IntroductionSerious fungal infections particularly Candida infection have increased in recent years as a consequence of increased immunosuppression associated with HIV infection, organ and tissue transplant and aggressive treatment for malignancies and autoimmune diseases. Present study was conducted to Characterize various Candida species isolated from various clinical samples, their virulence testing by biofilm production and antifungal susceptibility pattern.Settings and Design:A prospective observational study was conducted from September 2014 to June 2016 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 1–5 Read article
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Endosulfan-Induced Hepatotoxicity and its Amelioration by Administration of Bamboo (Dendrocalamus Strictus) Seed Extract in Rats
Abstract: Endosulfan is an important hepatotoxic agent that generates free oxygen radicals in liver and the incidence of toxic injury to the liver tissue in relation to its widespread has been reported. Bamboo is rich in phenolic components which possess various bioactivities and bamboo seed extract was found to have antioxidative properties. Hence, the present study has been designed to assess the protective role of bamboo seed extract against endosulfan induced …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 1–7 Read article
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Diet Management of Cancer Patients Who Undergo Chemotherapy—An Experimental Study
Abstract: Background: Chemotherapy is the one major treatment module for cancer patients, but it has so many side effects, including nausea, vomiting, fatigue, and pain. These side effects reduce the adherence towards chemotherapy and reduce the interest to have foods. This, in turn, affects the normal tissue metabolism and disturbs the functions of cell and tissue regeneration. Food is very important for patients who receive chemotherapy. The cyclic administration of chemotherapy …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 1, 2024 · pp. 17–21 Read article
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Role of Transcription factor AP-1 in Breast carcinoma
Abstract: Breast cancer is a major health problem of today. Transcription factor is nothing but protein that is needed for transcription. Activator protein-1 (AP-1) is a transcription factor of complex oncogene proteins (Jun and Fos). Fos and Jun family participate in many cellular processes which includes proliferation, differentiation and carcinogenesis. Therefore, this study has been designed to study level of transcription factor AP-1 in breast carcinoma. The study was carried on …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 2, 2019 · pp. 22–28 Read article
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
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Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings
Abstract: Recent developments in the field of polymer chemistry have resulted in many new forms of Hybrid polymer. This has further revolutionized the application of polymer chemistry in numerous fields. In this research, we manufactured clay-based hybrid membrane by adding clay to the biodegradable matrix of chitosan polymer. It is widely known that microbial and pathogenic organisms are responsible for wound hampering infections such as impetigo. They can spread in bodily …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 13–20 Read article
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Effect of Local Application of Phenytoin on Wound Healing in Surgical Wounds: A Scientific Review
Abstract: Surgical wound healing is a dynamic biological process influenced by local tissue response, vascularity, infection control, and systemic patient factors. Delayed wound healing contributes significantly to postoperative morbidity and healthcare costs. Phenytoin, a hydantoin derivative traditionally used as an antiepileptic agent, has demonstrated unexpected wound-healing properties when applied topically. This review critically evaluates experimental and clinical evidence regarding the role of locally applied phenytoin in enhancing wound healing in surgical …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 15–19 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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Molecular Diagnosis of Rifampicin Antibiotic Resistance in Mycobacterium Avium Subspecies Paratuberculosis Isolated from Sheep Clinical Samples
Abstract: The present study was conducted to identify parts of the rpoB gene in MAP of Indian sheep isolates. The rpoB gene (Beta sub unit of RNA polymerase) is involved in conferring the rifampicin antibiotic resistance in MAP bacteria. The resistance is due to the presence of mutations in the 81 bp variable region of the rpoB gene including C1367T and T1442C mutations identified by several workers. The study was further …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 3, 2022 · pp. 35–56 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article