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47 articles for “hormonal regulation”
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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Assessment of Vitamin D Levels Among Hashimoto and Hypothyroidism Disease in Iraq, A Comparative Study
Abstract: The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 77–83 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Optimizing Chromatographic Techniques for Comprehensive Paraben Analysis to Enhance Safety in Consumer Products
Abstract: Parabens (PBs), such as methylparaben (MePB), ethylparaben (EtPB), propylparaben (PrPB), and butylparaben (BuPB), are widely used as preservatives in pharmaceuticals, food, and personal care products due to their antibacterial properties. However, there are growing worries about their potential to disrupt hormonal functions, which has led to stricter regulations. This study focuses on creating a robust high-performance liquid chromatography (HPLC) method for quickly measuring all four parabens in consumer goods. We …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 228–243 Read article
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Serum Magnesium, Iron, TIBC, and Hormonal Imbalances in Hypertensive Pregnant Women: A Comparative Study
Abstract: Pregnancy-induced hypertension (PIH), including gestational hypertension and preeclampsia, is a leading cause of maternal and fetal complications. The regulation of blood pressure and overall pregnancy health is influenced by micronutrients and hormones. This study aimed to evaluate serum magnesium, serum iron, total iron binding capacity (TIBC), thyroid profile, and quadruple marker levels in hypertensive pregnant women and compare them to normotensive controls. Methods: A total of 1056 hypertensive pregnant women …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 41–45 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Lesser-Known Metabolites Influencing Ovarian Function, Follicular Development, and Embryo Viability in Dairy Cows
Abstract: The intricate processes of ovarian function, follicular development, and embryo viability in dairy cows are tightly regulated by a complex network of metabolites. While conventional biomarkers, such as steroid hormones, amino acids, and glucose metabolites, have been extensively studied, a growing body of evidence suggests that lesser-known metabolites play pivotal roles in bovine reproductive physiology. Dairy cattle fertility is critical for maintaining optimal milk production and herd sustainability, necessitating deeper …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 18–29 Read article
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Recombinant Human EGF in Wound Healing: 3D Computational Insights
Abstract: A Growth Factor represents a naturally-occurring compound with the remarkable ability to incite cellular growth, proliferation, and differentiation. Typically manifesting as either a protein or a steroid hormone, these factors wield significant influence over an array of cellular activities. Their pivotal role lies in the regulation of diverse cellular processes, often serving as catalysts for cell specialization and maturation, a characteristic that distinguishes them from one another. For instance, bone …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 6–10 Read article
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Arabidopsis thaliana. (L.) Heynh Multifunctional Sensor Proteins and Signaling Networks Plant Photoreceptors
Abstract: Light is a crucial environmental cue for the growth and development of plants as well as the production of photosynthetic energy. In order to recognize and process information from incoming light, plants employ sophisticated mechanisms. With the model plant Arabidopsis thaliana, five different types of photoreceptors have been found. (L.) Heynh Photoreceptors play a specialized and/or recurring role in fine-tuning many aspects of the plant's life cycle. Unlike mobile animals, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 08–24 Read article
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Fenugreek: A Traditional Herb with Modern Health Applications
Abstract: Fenugreek (Trigonella foenum-graecum) is a remarkable herb with a rich history that stretches back over 4, 000 years. It has played an important role in traditional medicine systems like Ayurveda, Unani, and Traditional Chinese Medicine. Cultivated widely in places like India, the Mediterranean, and North Africa, fenugreek’s seeds and leaves have been used to treat a variety of ailments, from digestive and respiratory issues to skin problems and inflammation. Recent …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 11–21 Read article
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Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
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Synthesis of Brassinosteroid with Signaling and Response to Abiotic Stress: Review
Abstract: Brassinosteroids (BRs) are a group of plant steroid hormones with multiple roles in plant growth, development, and responses to stresses and signaling functions to promote cell expansion and cell division and plays a role in etiolation and reproduction. The entire synthetic pathway of sterol biosynthesis is brassinolide (BL) from the general campesterol synthesis pathway in Arabidopsis. Campesterol converts to BL in two different ways campesterol dependent or campesterol independent pathway. …
Published in Research & Reviews : Journal of Botany Read article
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Prolonged Antibiotic Use and Reproductive Challenges in Dairy Cows: Implications for Ovarian, Uterine, and Overall Reproductive Health
Abstract: The widespread use of antibiotics in dairy farming has raised concerns regarding its potential impact on reproductive performance. Prolonged antibiotic administration can disrupt endocrine regulation, alter ovarian function, impair uterine health, and compromise overall fertility in dairy cows. This review explores the multifaceted consequences of antibiotic exposure on reproductive physiology, highlighting its effects on hormonal balance, follicular dynamics, uterine microbiota, and embryo viability. Antibiotics may induce hormonal imbalances that interfere …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 22–40 Read article
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A Review of the Role of Fiber Supplements in Digestive Health and Weight Management
Abstract: The essential component of a nutritious diet is dietary fiber which enables body weight regulation and maintains digestive system health. Several supplements derived from fiber have gained popularity during recent years since they help improve gut health while controlling weight and preventing metabolic diseases. The two major groups which make up fiber are soluble and insoluble fibers that impact the body differently. The soluble fiber components psyllium inulin and beta-glucans …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 24–35 Read article
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Partitioning Dynamics of Nutrients in Transition Dairy Cows: Metabolic, Hormonal, and Cellular Mechanisms Affecting Lactation and Fertility
Abstract: This review critically examines nutrient partitioning dynamics in dairy cows during the transition phase, a period that profoundly affects lactation and reproductive performance. During this phase, cows experience extensive physiological changes that alter nutrient requirements and utilization, making effective management essential for health and productivity. The review synthesizes current research on mechanisms of nutrient partitioning, with particular attention to energy, protein, and mineral balance, which are crucial for optimizing milk …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Social Dynamics and Behavioral Influences on Puberty Onset in Dairy Heifers: A Comprehensive Study
Abstract: Puberty onset in dairy heifers is a critical milestone for reproductive efficiency and overall herd productivity. This study investigates the multifaceted roles of social dynamics and behavioral interactions in determining the timing of puberty in dairy heifers. By examining both individual and group-level behaviors, the research explores how factors, such as social hierarchy, peer interaction, environmental stimuli, and stress response contribute to variations in puberty onset. The study integrates observational …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 6–13 Read article
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AQUASOMES: A Vesicular, Self-assembled Ceramic Nanoparticulate Drug Carrier
Abstract: Nano-biopharmaceutics involves delivery of biopharmaceutical product through different biomaterials like multi-functional nanoparticles, quantum dots, aquasomes, super-paramagnetic iron oxide crystals, and liposomes dendrimers. Aquasomes are considered as one of the most recently developed delivery systems for bioactive molecules like peptides, proteins, hormones, antigens and genes to specific sites. Aquasomes have a spherical shape and a particle size of 60–300 nm. These are three layered self-assembled nano-particulate carrier system. This three-layered structure …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article
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The Effects of Steroids on One’s Health
Abstract: The widespread use of steroids for both medicinal and non-medical purposes is a significant issue in contemporary culture. This article examines the considerable impact of steroids on human health, focusing on the therapeutic benefits and the adverse side effects associated with their consumption. In the treatment of conditions, such as inflammation, autoimmune disorders, and hormone imbalances, steroids, are frequently prescribed, providing significant relief from symptoms. However, the abuse of these …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 47–63 Read article