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68 articles for “clinical samples”
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Impact of Diabetes on Quality of Life of Patient with Diabetes in West Tripura
Abstract: Throughout the new millennium, diabetes mellitus is on the rise everywhere. According to IDF, the prevalence of diabetes in worldwide was 537 million in 2021; this number is anticipated to climb to 643 million by 2030 if no effective preventative measures are introduced. According to an IDF research, one in three households has diabetic patients, and one in seven adult diabetics worldwide lives in India. India's percentages were 9.3% in …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 17–28 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Effect of Nebulization With 3% Hypertonic Saline for Airway Clearance on Mechanically Ventilated Patients Admitted in ICUs of Pt. B.D. Sharma, PGIMS, Rohtak
Abstract: Background of the Study: The ability to breathe artificially prolongs life in many situations. Patients requiring mechanical breathing in the intensive care unit are more likely to have complications and even death due to a variety of interconnected causes. As a result, it became critical to rapidly ventilate in the safest and most efficient manner available. Intubated patients have benefited from nebulized suctioning, as it improves lung clearance and decreases …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 20–27 Read article
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Molecular Surveillance of Spring Viraemia of Carp Virus (SVCV) and Koi Herpesvirus (KHV) Across Major Aquaculture Zones of Telangana, India
Abstract: Viral diseases represent a persistent threat to cyprinid aquaculture; however, region-specific surveillance data from tropical production systems remain limited. To address this gap, a comprehensive statewide active surveillance programme was undertaken across Telangana, India, from 2019 to 2022 to investigate the occurrence of two priority transboundary pathogens, Spring Viraemia of Carp Virus (SVCV) and Koi Herpesvirus (KHV). A total of 414 fish specimens were systematically collected from five surveillance sectors …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Interfacial Performance and Structural Stability of Repaired vs. Replaced Polymer-Based Composites: A 3-Year Retrospective Analysis of 'Patch-up' Restorative Engineering
Abstract: Objective: This retrospective study aimed to evaluate the clinical longevity and interfacial success of repairing aged polymer-based composites versus complete replacement, focusing on the integration between the existing polymer matrix and the new restorative material. Materials and Methods: A retrospective clinical audit was conducted on 50 cases (n = 50) of posterior restorations with localized defects. The sample was categorized into: Group A (n = 25), where defective sites were …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 180–187 Read article
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A Study to Assess the Risk Factors and Symptoms of Dialysis Disequilibrium Syndrome among Patients Undergoing Hemodialysis
Abstract: Dialysis Disequilibrium Syndrome (DDS) is a rare but potentially life-threatening neurological complication associated with hemodialysis, particularly during initiation or in high-risk patients. It is characterized by a spectrum of neurological manifestations ranging from mild symptoms such as headache and nausea to severe outcomes including seizures, coma, and death. Early identification of risk factors and prompt recognition of symptoms are crucial to prevent morbidity and mortality. The present study aimed to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Metabolic Syndrome in Psoriatic Patients: A Cross-Sectional Study
Abstract: Background: Psoriasis is a chronic immuno-inflammatory disease affecting the skin and joints. Studies have demonstrated an increased prevalence of conventional cardiovascular risk factors such as diabetes mellitus, hypertension, and metabolic syndrome in these patients. The aim of this study was to determine the association between psoriasis and metabolic syndrome. Material and Method: An observational cross-sectional study was carried out between November 2023 and October 2024, including participants with and without …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 17–23 Read article
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Infection Control awareness among Nursing students: Descriptive Insights from Ongoing Clinical Orientations in Odisha
Abstract: Background: Effective infection control practices are critical in preventing healthcare-associated infections (HAIs). Aim: This study aimed to assess the awareness regarding effective infection control measures among student nurses undertaking their initial clinical orientations at Hospitals. Method: The study accepted 64 respondents from II-year BSc Nursing, sampled in clusters from selected Hospitals, Odisha. Results: The students yielded a mean awareness score of 0.69, categorized as Good. A comparison revealed that female …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article
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Clinical Profile of Dengue Patients who had a Prior Infection with the Covid 19 Virus in a Tertiary Care Centre
Abstract: This cross-sectional analytical study conducted in a tertiary care center aims to investigate the clinical profile of Dengue virus-infected patients with a prior history of COVID-19 within the last three years. Dengue, a prevalent tropical disease, ranges from mild fever to severe conditions like hemorrhagic fever and shock syndrome. The study utilizes the World Health Organization's 2009 classification for Dengue and delineates the febrile, critical, and recovery phases of infection. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 34–38 Read article
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Patient Profile and Antimicrobial Susceptibility Testingin Clinical Isolates of Staphylococcus aureus
Abstract: INTRODUCTION: Staphylococcus aureus is a gram-positive bacterium capable of causing various infections, ranging from minor skin infections to serious bloodstream infections. The rise of methicillin-resistant S. aureus (MRSA) strains has made treating these infections more challenging, as MRSA is frequently resistant to several types of antibiotics.. OBJECTIVE: The aim of this study was to investigate the patient profile and antimicrobial susceptibility patterns of clinical isolates of S. aureus in a …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 31–38 Read article
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Knowledge and Practice of Self-Administration of Insulin Injections among Diabetic Patients
Abstract: High blood glucose levels are a hallmark of diabetes mellitus, a chronic and crippling illness. According to estimates from the World Health Organization (WHO), 530 million persons globally have diabetes. Diabetes management requires education, and educating patients how to administer insulin injections on their own can give them the power to take charge of their health. The purpose of this study was to evaluate diabetic patients who visited the diabetes …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 29–33 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article
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Comprehensive Strategies for the Prevention and Management of Genital Thrush in Males and Females: A Public Health Approach in Punjab (September 2024 to February 2025)
Abstract: Background: Genital thrush, a common fungal infection caused mainly by Candida albicans, affected both men and women, leading to itching, discomfort, and recurrent infections. In Punjab, high humidity, poor hygiene awareness, excessive antibiotic use, and limited access to healthcare contributed to its widespread occurrence. Without effective prevention and management strategies, the condition significantly impacted quality of life. Addressing this issue through a public health approach was essential for reducing its …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
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Lower Genital Tract Infections in Pregnant Women: Epidemiology and Risk Factors Associated in Dakar, Senegal
Abstract: Vaginal infections are responsible for many problems in women of childbearing age and significantly influence pregnancy outcomes. This study sought to ascertain the prevalence of lower genital tract infections and the risk factors associated with them in pregnant women under observation at the Nabil Choucair Health Centre in Dakar, Senegal. This nine-month cross-sectional study, which involved women between 34 and 38 weeks gestation (WG), was carried out from July 2020 …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 47–59 Read article
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Passive Digital Phenotyping for Longitudinal Burnout and Occupational Mental Health Surveillance: A Transformer-Based Explainable Deep Learning Approach Using Smartphone Behavioral Streams
Abstract: Occupational burnout constitutes a pervasive yet chronically under-surveilled public health threat, its insidious temporal evolution rendering episodic self-report instruments structurally inadequate for early detection. This paper introduces BurnoutSense, a passive digital phenotyping framework that continuously harvests eight heterogeneous smartphone behavioral data streams encompassing application usage ecology, communication metadata, geospatial mobility, screen interaction dynamics, inferred sleep rhythmicity, keystroke kinematics, ambient noise exposure, and battery/charging cadence to construct individualized multivariate behavioral signatures …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 44–53 Read article
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A Study to Evaluate the Effectiveness of Planned Teaching Program on Diabetic Management Regarding Knowledge and Practice Among Patients with Diabetes Mellitus at Selected Taluk Government Hospital, Kollegala
Abstract: Diabetes mellitus is a chronic metabolic disorder with a growing global impact. Effective management of this condition requires not only medical intervention but also comprehensive patient education. This study was conducted to evaluate the effectiveness of different diabetes education methods on improving metabolic control, body mass index (BMI), and blood pressure among diabetic patients. The research aimed to empower individuals with diabetes by enhancing their knowledge and self-management skills. A …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 19–28 Read article
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Patterns and Variations in Complementary Feeding Practices Among Mothers of Children Aged 6–24 Months Attending Immunization Clinics in Mandi Gobindgarh, Punjab, India
Abstract: Introduction: Complementary feeding introduces solid or semisolid foods to an infant’s diet while breastfeeding. In India, feeding infants and young children is determined by their socioeconomic status, cultural practices, and healthcare access. The study assesses the feeding practices of mothers with children aged 6–24 months who come for immunization at Mandi Gobindgarh, Punjab. Methods: A cross-sectional study was conducted with 350 mothers selected through systematic random sampling. A structured questionnaire …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 43–53 Read article