Search
116 articles for “antibiotic-resistant”
-
Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
-
Properties and antimicrobial activity of bacterial nanocellulose composite incorporated with silver nanoparticles based on green synthesis
Abstract: Green silver nanoparticles (AgNPs) synthesized using medical plant extracts as capping and reducing agents demonstrate broad applicability in addressing the threat posed by infections. In this study, we present a sustainable, low-toxicity, and cost-effective bacterial nanocellulose composite with silver nanoparticles based on green synthesis that uses Origanum vulgare as a reducing agent due to numerous biological components. The formation of AgNPs in composite and morphological properties was analyzed using scanning …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 323–328 Read article
-
Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
-
Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
-
Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
-
Bacteriophage Therapy in Dairy Farming: A Potential Alternative to Antibiotics
Abstract: The widespread use of antibiotics in dairy farming to control bacterial infections has led to significant challenges, including the emergence of antibiotic-resistant bacteria and concerns over antibiotic residues in milk. Consequently, there is an increasing demand for alternative approaches to control bacterial infections in dairy cattle. One promising solution is bacteriophage therapy, which uses viruses that selectively infect and destroy bacteria. As a result, the need for new strategies to …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–5 Read article
-
Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
-
A Study to assess Prescription pattern in outpatient department of tertiary care hospital
Abstract: ABSTRACTBackground:Antibiotic resistance and irrational prescribing is a global concern, is particularly pressing in developing nations, including India, where the burden of infectious disease is high and healthcare spending is low. The Global Antibiotic Resistance Partnership (GARP) was established to develop actionable policy recommendations specifically relevant to low- and middle-income countries where suboptimal access to antibiotics - not a major concern in high-income countries - is possibly as severe a problem …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 2, 2018 · pp. 33–36 Read article
-
Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
-
Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
-
Aloe vera: A Review on Its Medicinal Importance
Abstract: Today, one of the main causes of human infection is the antibiotic resistance of bacteria due to the use of antibiotics which causes the emergence and spread of antibiotic-resistant bacterial strains. The search for the discovery of healthy and effective antimicrobial agents continues. Aloe vera can be used for both therapeutic and preventive purposes in the case of a broad range of bacterial infections. Aloe vera is a medicinal plant …
Published in Research and Reviews : Journal of Crop science and Technology Read article
-
Promising Antimicrobial Compounds from an Endophytic Fungus Penicillium daleae EF 4 Isolated from the Seaweed Enteromorpha flexuosa Linn.
Abstract: AbstractThe present aim of the study is to isolate the endophytic fungi from various seaweeds and to screen their bioactivity, to analyze the β-lactamase inactivator and to evaluate the interactions between the crude extract of Endophytic fungi Penicillium daleae EF 4 and two antibiotics (penicillin G and tetracycline), against some antibiotic resistant bacterial strains. Seaweeds collected from various places of Bay of Bengal coast was subjected to Endophytic fungal isolation. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 26–39 Read article
-
Identification of ESBL producing Escherichia coli from Urine Samples at Tertiary Care Hospital in Jhalawar
Abstract: Introduction: Antibiotic resistance (ABR) is a serious worldwide threat to public health due to the emergence of multidrug resistant bacteria and is considered as a great problem in the treatment of bacterial infections both in hospital as well as community settings. Extended Spectrum Beta-Lactamase (ESBL) producing strains have emerged as a significant challenge to counter with present antibiotics. Aims: Our study was aimed to know the prevalence of ESBL producing …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 38–45 Read article
-
To Compare the Anti-Bacterial Activity of Uva Ursi 200 And Cantharis Vesicatoria 200 In Isolated E-Coli of Different Urine Samples by Kirby Bauer Disc Diffusion Method
Abstract: Background: The most common bacterial infections are Urinary Tract Infections (UTI), primarily caused by Escherichia coli (E. coli), a gram negative bacterium responsible for 80-90% of community-acquired UTIs. The rise of antibiotic-resistant E. coli strains has increased the demand for Homoeopathic remedies. This study explores the antibacterial efficacy of Uva ursi 200 and Cantharis vesicatoria 200, using Kirby-Bauer Disc Diffusion Method, by comparing the Zone of Inhibition (ZOI) of those …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2026 Read article
-
Antibiotics in the Modern Era: Challenges, Misuse, and the Fight Against Resistance
Abstract: Overuse and inappropriate use of antibiotics in human medicine, agriculture, and environmental pollution. It is one of the biggest public health risks of the 21st century. The discovery of new antibiotics slowdown and the emergence of multidrug-resistant (MDR) microorganisms has highlighted the urgent need to Creative approaches to fighting opposition. This review explores the current challenges in antibiotic use, the factors driving resistance, and the strategies being implemented to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 57–70 Read article
-
Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
-
Zinc Oxide Nanoparticles from Murayya koenigii: Antibacterial Potential Review
Abstract: Nanoparticles (NPs) display unique characteristics in contrast to conventional physico-chemical synthesis methods, and they are utilized in various life science fields including surface coating, catalysis, food packaging, corrosion prevention, environmental cleanup, electronics, biomedical applications, and antimicrobial purposes. Metal NPs synthesized through green methods, particularly from plant origins, have garnered significant interest because of their inherent traits such as environmental friendliness, quick production, and cost efficiency. Over the past few years, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 54–67 Read article
-
An Enhanced Fish Feed Supplemented with Probiotics and Spirulina Formulation for Commercial Production
Abstract: In recent years, the probiotics isolated from fish gut microbiota is used in aquaculture practices as there is a demand to improve the quality of life of fishes. The aim of the study is to isolate probiotic microbe from the gut of Etroplus suratensis and to evaluate the most suitable probiotic for feed formulation. Two bacterial isolates from the gastrointestinal tract (GI) of Etroplus suratensis was evaluated for probiotic properties. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 2, 2020 · pp. 1–7 Read article
-
Exploring the Potentials of Quercetin and Kaempferol combinations along with Regular Antibiotics for the Effective Management of Methicillin-resistant Staphylococcus aureus (MRSA)
Abstract: The methicillin-resistant S. aureus (MRSA) is a bacterium that offers the challenge to numerous antibiotics which leads to a variety of problems, ranging from skin infections and sepsis to pneumonia. The natural products based management somewhat opened hope towards the betterment of the present era where the combination with currently available medicines has been studied clinically. Antibiotics (cefixime, ceftriaxone, erythromycin, ciprofloxacin, cephradine, methicillin, ampicillin, levofloxacin, and amoxicillin) and flavonoids (quercetin, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 6–9 Read article
-
Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article