Search
38 articles for “antibiotic sensitivity”
-
Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
-
Bacteriological and Yeast Profile in Clinical Samples from Immunocompromised Persons (Especially in HIV and Cancer Patients) and Their Antimicrobial Susceptibility Pattern
Abstract: AbstractImmunocompromised host describes a patient who is on increased risk to acquire infection due to congenital or acquired abnormality of the immune system. In the past few decades, the population of immunocompromised hosts has expanded enormously, due to the increased use of immunosuppressive conditions like HIV, cancer, etc. This study was planned to know the spectrum of organisms and trend of antimicrobial susceptibility pattern in immunocompromised patients. All hospitalized patients …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 1, 2017 · pp. 1–8 Read article
-
Role of Nanotechnology in the Diagnosis and Treatment of Waterborne Diseases
Abstract: Nanotechnology provides new aspects for the treatment and diagnosis of diseases using atomic scale engineering of materials. The size of nanoparticles is similar to that of most biological molecules and structures; therefore, nanoparticles can be useful for both in vivo and in vitro biomedical research and applications. At the same time, the unique dimension of nanoparticles empowers them with special capabilities to successfully deliver the drug at the desired site. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 4, Issue 1, 2014 · pp. 19–28 Read article
-
Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
-
Respiratory Tract Infection: A Focus on Upper Respiratory Tract Infection
Abstract: Respiratory tract infection (RTI) is considered as one of the most important public health problems in developing countries. Respiratory infections that occur in upper respiratory tract are seen with great frequency in both children and adults. RTIs are common cold, sore throat, sinusitis, laryngitis, pharyngitis, earache, and otitis media. Upper respiratory tract infections (URTIs) are general illnesses that are often treated with antibiotics even though bacteria cause only 25% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 30–35 Read article
-
Determination of Gatifloxacin in Human Urine by Liquid Chromatography-Tandem Mass Spectrometry
Abstract: Gatifloxacin (GTF) is an antibiotic of the fourth-generation fluoroquinolone family that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. A reliable, sensitive and selective isocratic reversed phase liquid chromatographic-tandem mass spectrometric (LC-MS-MS) method was developed to determine gatifloxacin (GTF) in human urine. GTF, in urine after solid-phase extraction with SPE cartridge, was analyzed on a C18 column (Symmetric 3.5 μm; 75×4.6 mm i.d) interfaced with a triple quadrupole tandem …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 1, 2015 · pp. 1–6 Read article
-
Biological Synthesis of Silver Nanoparticles Using Hibiscus Sabdariffa Leaf Extract and It’s Antibacterial Sensitivity Assay
Abstract: In this study, AgNO3 was effectively used to synthesize silver nanoparticles. Hibiscus sabdariffa leaf extract was used to promptly and easily synthesize silver nanoparticles. An UV-Visible spectrophotometer showed absorbance peak in range of 300-600 nm. The procedure was found to be easy to follow, quick, least step and safe for the environment. It is non-toxic, and a viable substitute for traditional physical or chemical procedures. At room temperature, silver ions …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 08–13 Read article
-
Bacterial Spectral in UTI in a Hospital Environment
Abstract: Urinary tract infections (UTIs) represent a significant public health issue, primarily caused by a variety of pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. UTIs contribute substantially to illness and complications in individuals with pre-existing health conditions and account for a large portion of hospital visits globally. UTIs are usually self-limiting in people with no structural or functional problems, but they do tend to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
-
Study The Effect of The Alcoholic and Hot Aqueous Extract of Costus specious on Some Bacterial Species
Abstract: Plant extracts are among the methods that have been used since ancient times in alternative medicine and are still developing until recently with the progress of science and modern technologies. These materials can be used in the composition of many pharmaceutical drugs. The current research aimed to evaluate the inhibitory effect of alcoholic and hot aqueous extract of the roots of Costus specious on some gram-positive and gram-negative bacteria (Enterococcus …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 13–18 Read article
-
Microbes: A General Review
Abstract: The exploration of microbes has been a vibrant field of study for over 250 years. Microbiology, in particular, has made significant strides in recent decades, enabling precise diagnosis and treatment of numerous infectious diseases. Today, infectious diseases continue to pose challenges for human health. To mitigate the risks of various infections, there is a growing emphasis on enhancing the production and utilization of antibiotics, which are synthesized from microbial sources. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 48–54 Read article
-
The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
-
DRUG INDUCED IMMUNE MEDIATED NEPHRITIS: MOLECULAR MECHANISM , PATHWAYS AND CLINICAL IMPLICATIONS
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
-
Evaluation of Antibacterial Sensitivity of Euphorbia hirta Linn. Leaf Extract
Abstract: AbstractEuphorbia hirta L. (Asthma Lata), a pantropic herbaceous wild plant which has been widely used as a medicinal plant throughout Bangladesh. The present study was designed to evaluate the antimicrobial activity of ethanolic and methanolic leaf extracts of E. hirta against six pathogenic bacteria viz. Bacillus subtilis, Sarcina lutea, Xanthomonas campestris, Escherichia coli, Klebsiella pneumonia and Pseudomonas sp. by disc diffusion method. Both crude extracts of E. hirta exerted the …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 1, 2013 · pp. 13–17 Read article
-
Ventilator Associated Pneumonia: Prevalence of Bacteria and their Antibiogram in Tertiary Care Centre, Kota, Rajasthan, India
Abstract: Background: Mechanical ventilation is a life-saving procedure, but it is associated with a high risk of acquiring respiratory infections. Hence to prevent it and initiate empirical antimicrobial therapy, knowledge of microbial profile and their local antimicrobial sensitivity pattern are essential. The study aimed to investigate the role of endotracheal aspirate (ETA) surveillance cultures in identifying the aetiology of VAP earlier. Methods: A prospective study was carried out over a period …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 1, 2021 · pp. 30–34 Read article
-
Detection and Control of Adulterants in Milk
Abstract: Milk is one of the most essential and widely consumed staple foods, valued for its rich nutritional composition, including proteins, fats, vitamins, and minerals necessary for human growth and health. However, the increasing demand for milk, coupled with economic incentives, has led to the widespread issue of milk adulteration, posing serious concerns for food safety and public health. Adulteration involves the addition of harmful or inferior substances to milk, either …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 15, Issue 1, 2026 · pp. 1–6 Read article
-
Standard Diagnostic Procedure for Tuberculosis: A Review
Abstract: Normal 0 false false false EN-US X-NONE NE Despite continuous effort in monitoring and treatment of tuberculosis, the disease remains a major public health issue. Rapid diagnosis and appropriate therapies become the first priorities in controlling the growing epidemics. The bedside decision on the initiation of anti-tuberculous drug therapy are based on epidemiologic, clinical, radiolographic, and/or histological findings, which can generally be supported by a rapid microbiologic test, commonly a …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 34–40 Read article
-
Prevalence of Multidrug-Resistant Enterobacteriaceae Causing Urinary Tract Infection
Abstract: Urinary tract infections are one of the most common causes of hospital admission, high morbidity and mortality. The most common cause of urinary tract infection is Gram-negative bacteria such as Escherichia coli, Proteus spp., Pseudomonas aeruginosa, Acinetobacter spp., Klebsiella spp., Enterobacter spp., Citrobacter spp. and Gram-positive bacteria such as Enterococcus spp., Staphylococcus aureus and Coagulase-negative Staphylococci. Multidrug-resistant Enterobacteriaceae are emerging worldwide due to high empiric and injudicious use of antibiotics. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 13–18 Read article
-
Perceptions of Health Care Providers and the Community on the Management of Possible Serious Bacterial Infection (PSBI) in Young Infants where Referral is not Possible: A Qualitative Study
Abstract: Introduction: Every year, about 2.8 million children die in the first month of life, with 98% of these deaths occurring in developing countries. The current World Health Organization recommendation for management of infections in neonates and young infants (0–59 days old) is referral for hospital treatment with a 7 to 10 day course of a combination of two injectable antibiotics – Penicillin or Ampicillin plus Gentamicin. However, existing evidence demonstrates …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 23–27 Read article