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169 articles for “Validation”
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Realtime Life Cycle Assessment, Synthesizing Life Cycle Inventory with Business Process Management, Sustainable Growth in the Fourth Industrial Revolution
Abstract: A prevalent methodology for evaluating the ecological impacts of processes and products throughout their entire life cycle is known as Life Cycle Assessment (LCA). This approach involves scrutinizing each phase, encompassing the extraction of raw materials, manufacturing, utilization, and disposal. Nevertheless, conventional LCA methods often fail to account for the dynamic nature of industrial processes and are deficient in real-time data. The Life Cycle Inventory (LCI), a pivotal component of …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Cosmeceuticals: Integrating Therapeutic Functionality into Cosmetic Science
Abstract: Cosmeceuticals are a quickly growing group of skincare products that are in between cosmetics and drugs. These products have biologically active components that are said to provide medical or drug-like advantages for a number of skin problems, including ageing, hyperpigmentation, acne, and damage from the sun. Cosmetics are not medications, but cosmeceuticals are made to affect skin function at the cellular level. This article talks about what cosmeceuticals are, how …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 19–35 Read article
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Fracture Analysis of FRP Composites under Thermo-Mechanical Loads for Different Geometry Cutouts
Abstract: Fiber-reinforced composites (FRPs) are used extensively in structural and non-structural components of the aerospace and automotive industries. To utilize these materials for structural applications, it is necessary to understand the fracture behavior of the material. In the present investigation of carbon fiber laminates, studies were carried out to understand the fracture toughness characteristics of the carbon fiber laminates with mechanical, thermal, and thermo-mechanical loadings of modes I, II, and III. …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Emotion Recognition from Electroencephalogram Signal and Eye Movement Based on Deep Learning
Abstract: Emotion recognition from electroencephalogram (EEG) signals has gained significant attention due to its potential in human- computer interaction (HCI), mental health monitoring, and personalized content delivery. This paper presents the use of Convolutional neural networks (CNNs) to classify emotions such as happiness, sadness, fear, neutral, and disgust by leveraging a fusion of EEG signals and eye movements data. Compared to conventional methods of emotion detection, such as those that rely …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 8–15 Read article
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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Design and Analysis of Thermoelectric Dc boost converter
Abstract: In today’s consumer-oriented market, researchers are increasingly focusing on harvesting energy from ambient and renewable sources to enable sustainable power generation and reduce dependency on conventional energy resources such as batteries and fossil-fuel-based electricity. The rapid growth of portable electronics, wireless sensor networks, and Internet of Things (IoT) devices has created a significant demand for low-power, long-life, and maintenance-free energy solutions. In many practical situations, frequent battery replacement is difficult, …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 1–10 Read article
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LQR-Based Optimal Control of Inverted Pendulum System with State Estimation and Stability Analysis
Abstract: The inverted pendulum on a cart is a canonical benchmark problem in control systems engineering, capturing the essential challenges of stabilizing an inherently unstable, underactuated, and nonlinear plant. Classical Proportional-Integral-Derivative (PID) controllers, while widely employed in industrial practice, exhibit fundamental performance limitations when applied to such systems, primarily due to their inability to account for multivariable coupling, process noise, and the absence of a systematic optimization framework. This paper presents …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 1, 2026 · pp. 31–43 Read article
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Design, Mathematical Modeling, and Dynamic Optimization of a Speed Breaker-Based Vehicular Kinetic Energy Harvester
Abstract: Decentralized energy harvesting methods are becoming more popular due to rapid urbanization and the rising need for sustainable infrastructure. The road-embedded vehicle kinetic energy harvester (VKEH) design, mathematical modelling, and experimental validation are presented in this work. This paper presents the structural engineering, continuum mathematical modeling, and experimental validation of an optimized road-embedded vehicular kinetic energy harvester (VKEH). The mechanism utilizes a spring- loaded, low-friction rack-and-pinion transmission coupled with a …
Published in International Journal of Electrical Power and Machine Systems · Vol. 4, Issue 2, 2026 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Determination of fire Resistivity of Door and Window Materials at Portharcourt Markets in Nigeria
Abstract: The persistence of fire outbreaks in markets is a problem in Nigeria and the repetition of this problem is very frequent at Port Harcourt in Rivers State. To curtail this problem, research was made on the three major markets in Port Harcourt with the aim of determining the fire resistivity of their door and window materials, in order to generate guidelines for designing doors and windows of market buildings in …
Published in International Journal of Architectural Design and Planning · Vol. 1, Issue 1, 2023 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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To Propose an Effective Process for Refurbishment Projects: through BIM
Abstract: Building refurbishments include enhancing, upgrading, renovating, retrofitting, and repairing existing structures. The construction sector considers it to be an important component. Building refurbishment projects are known for their high degree of complexity and uncertainty, which frequently incorporates elements like design changes and inadequate or unavailable information that may lead to various issues. Issues related to different stages of refurbishment projects were identified through literature and case studies. According to the …
Published in International Journal of Architectural Design and Planning Read article
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Identification and Assessment of the Factors causing Cost Overrun in Housing Projects
Abstract: Poor cost performance is a major problem in construction industry, especially in developing countries like India. Statistics reveal that majority of the projects faces the issue of cost overrun. The interrelationship between the causes of cost overrun and stakeholders has not been explored yet. The aim of the research is to minimize the effects of project cost overrun. The objective of the study is to categorize and rank the potential …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 1, 2023 · pp. 17–34 Read article
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Identification of Promising Lead Compounds from Capsicum annuum Targeting BACE-1 for Alzheimer’s Disease Therapy: A Molecular Docking Study
Abstract: Background: Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide. Beta-secretase 1 (BACE-1) is an important therapeutic target for AD treatment. Capsicum annuum (CA) is a commonly consumed plant with potential neuroprotective properties. In this study, we aimed to identify potential lead compounds from CA that can target BACE-1 for AD therapy using molecular docking. Methods: A library of 15 compounds from CA was obtained from PubChem, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 40–49 Read article
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Instant Response Garbage Disposal Using Android Application
Abstract: Solid waste is a major concern for government bodies and is a consequence of development, modernization, and urbanization. It refers to anything that is not a gas or liquid and poses a serious threat to the natural environment. Solid waste is a type of refuse that can accumulate in a certain area for an extended period of time if not properly managed. The waste can persist in the environment until …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 18–24 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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Floating Cities from Concept to Creation :Neighbourhood Guide to the Future Development
Abstract: Today cities are overpopulated and only 40% of space is left to house the world's population by 2050. Due to ever rising sea level 90% of coastal cities will be affected by flooding by the end of the century. This research aims to study about the floating city as a substitute. Floating cities shape to construct all of the infrastructure required for a water-based metropolis while also providing contextual space …
Published in International Journal of Urban Design and Development Read article