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94 articles for “Risk factors”
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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A Systematic Review on Factors Contributing to Infertility
Abstract: Infertility is a multifactorial reproductive health condition affecting approximately 10–15% of couples worldwide and continues to represent a major clinical and social challenge. Despite substantial advances in assisted reproductive technologies, diagnostic methods, and therapeutic interventions, many couples still face difficulties in achieving pregnancy. The impact of infertility extends beyond physical health, often leading to emotional distress, social pressure, and financial burdens, especially in societies where parenthood is highly valued. Consequently, …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 31–35 Read article
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Genetic Counseling: A Pathway to Understanding and Managing Inherited Health Risks
Abstract: Genetic counseling is an essential aspect of personalized medicine that supports individuals and families in understanding the implications of inherited health conditions. With the rising prevalence of genetic disorders and advancements in genomic technologies, counseling provides critical insights into risk factors, diagnostic options, and informed decision-making. This paper explores the classification of genetic disorders, major genetic and environmental causes, and the expanding role of genetic counseling within India’s culturally diverse …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
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Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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A Narrative Review on an Insight of Herbal Origin Drugs and Their Traditional Medicine Formulations for the Treatment of Nephrolithiasis
Abstract: Ethnopharmacological relevance. There is no satisfactory treatment at present to cure or prevent kidney stone recurrences using predictable medicines. There are several marketed formulations in Ayurveda, Unani and Homeopathic Traditional Medicines (TM) have potential lithotriptic effects and clinical applications. In India, prevalence rates of complementary and alternative medicine (CAM) for the treatment of nephrolithiasis are being estimated at 63.9%. Aim of the review This review article intended to scientifically documented …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 14–30 Read article
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Conquering the IoT Frontier: Challenges Faced in India
Abstract: The internet of things (IoT) represents a transformative force reshaping the landscape of connectivity and communication, ushering in an era marked by seamless machine-to-machine interactions and the fluid exchange of data across diverse devices and systems. This paper undertakes an extensive exploration of the prevailing state of IoT advancement within India, with a particular emphasis on delving into the multifaceted realms of security concerns, inherent challenges, and burgeoning opportunities. By …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 16–21 Read article
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Stingless Honeybee’s Rare Sugar and PCSK 9 - LDLR Interaction, A New Hope for Hormone Dependent Breast Cancer Patients – An In-silico Study
Abstract: Hypercholesterolemia is a lipid disorder characterized by elevated levels of low-density lipoprotein (LDL), commonly known as "bad" cholesterol. This condition is a significant risk factor in the development and progression of hormone-dependent breast cancer, as well as in the emergence of resistance to hormonal therapy. One of the key regulators of cholesterol metabolism is the proprotein convertase subtilisin/kexin type-9 (PCSK9) protein, which facilitates the degradation of the LDL receptor (LDLR) …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Concurrent Infection of Influenza and COVID-19: A Review
Abstract: In December 2019, a novel coronavirus that causes respiratory illnesses was identified in Wuhan, China, and swiftly spread around the world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a virus that spreads via the respiratory system and can cause pneumonia. Members of the Orthomyxoviridae family include influenza viruses. Although there are four genera in this family, influenza is only caused by genera A and B, which are clinically important for …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 7–15 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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Epidermolysis Bullosa and Its Role in Cervical Cancer: An Overview
Abstract: Epidermolysis Bullosa is a group of uncommon genetic disorders that primarily affect the skin and mucous membranes. It is marked by severe skin fragility and the formation of blisters even after minor trauma. Traditionally, the focus of Epidermolysis Bullosa research has been on its dermatological manifestations, which include recurrent blistering, scarring, and the potential for infections due to the compromised skin barrier. However, recent advancements in Epidermolysis Bullosa research have …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Pregnancy-Induced Post-Natal Back Pain
Abstract: Pregnancy-induced post-natal back pain (PNBP) is a common condition that affects many women following childbirth, significantly impacting their quality of life and physical functioning. The physiological and anatomical changes during pregnancy, such as weight gain, altered posture, and hormonal changes, contribute to the onset of back pain. As the body prepares for delivery, the pelvis and spine undergo structural shifts that can strain the muscles and ligaments supporting the lower …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 25–31 Read article
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Assess the Knowledge Level Regarding Prevention of Cervical Cancer Among Bachelor of Science Students at Selected Nursing College in Bengaluru
Abstract: Background: Cervical cancer is a major global health concern and one of the primary causes of cancer-related fatalities in women, with particularly high incidence rates in India. Early detection and prevention are crucial, but awareness remains insufficient, especially among future healthcare professionals like nursing students. This study evaluates the knowledge of first-year Bachelor of Science (BSc) nursing students regarding cervical cancer prevention. Materials and Methods: A non-experimental, descriptive research design …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 21–25 Read article
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Air Pollution and Lung Cancer: A Deep Dive into the Impact in Southern India
Abstract: Lung cancer incidence is rising in Southern India, with air pollution, particularly PM2.5, emerging as a significant risk factor alongside smoking. A retrospective cohort study analyzed data from 1,500 lung cancer patients diagnosed between 2010–2020 across Chennai, Bangalore, and Hyderabad, using hospital records, cancer registries, and environmental monitoring stations. The study found that 73.3% of patients were male, 80.7% were smokers, and 42.7% were aged 60+. Chennai had the highest …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 24–30 Read article
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Assessment of Fire and Life Safety in Rural Settlements in India
Abstract: Fire incidents pose a significant threat to life and property in rural India, particularly in residences. Despite strides in urban fire safety, rural areas continue to face frequent fire incidents, posing significant risks to lives and properties. This paper presents a thorough review of existing literature on fire safety assessment in rural Indian settlements focusing on unique vulnerabilities specific to this context. In rural settings, various factors contribute to the …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 1, 2024 · pp. 47–53 Read article
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Enhancing Security and Privacy in Smart Factory: A Blockchain Based Solution
Abstract: The manufacturing industry is currently experiencing a transformative shift due to the rise of smart factories, propelled by interconnected devices and automated systems. However, this integration of diverse technologies within smart factories introduces significant concerns regarding security and privacy. This research paper thoroughly investigates the vulnerabilities and threats prevalent in smart factory ecosystems, shedding light on the potential risks associated with centralized data storage and communication channels. The study emphasizes …
Published in International Journal of Wireless Security and Networks · Vol. 2, Issue 1, 2024 · pp. 13–20 Read article
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Partitioning Dynamics of Nutrients in Transition Dairy Cows: Metabolic, Hormonal, and Cellular Mechanisms Affecting Lactation and Fertility
Abstract: This review critically examines nutrient partitioning dynamics in dairy cows during the transition phase, a period that profoundly affects lactation and reproductive performance. During this phase, cows experience extensive physiological changes that alter nutrient requirements and utilization, making effective management essential for health and productivity. The review synthesizes current research on mechanisms of nutrient partitioning, with particular attention to energy, protein, and mineral balance, which are crucial for optimizing milk …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Epidemiology of Stomach Cancer in Northeastern States of India: Focusing on Nagaland and the Effectiveness of Screening Programs
Abstract: Stomach cancer represents a critical public health burden in northeastern India, with Nagaland exhibiting the highest age-standardized incidence rate in the country - nearly triple the national average. This elevated risk profile stems from multiple factors including traditional dietary practices (high consumption of smoked meats and fermented foods), widespread Helicobacter pylori infection (affecting approximately 70% of adults), prevalent tobacco/alcohol use, and limited healthcare infrastructure. Despite demonstrated success of endoscopic screening …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Atmospheric Determinants of Feed, Fodder, and Forage Contamination in a Changing Climate: Emerging Challenges for Sustainable Livestock Production
Abstract: Feed, fodder, and forage contamination represents a growing constraint to sustainable livestock production under a changing climate. Atmospheric determinants such as rising temperature, altered precipitation patterns, increased humidity, elevated carbon dioxide concentration, and enhanced aerosol and pollutant loads are increasingly recognized as critical drivers of contamination risks across feed supply chains. These atmospheric factors directly and indirectly influence crop growth, fungal proliferation, mycotoxin biosynthesis, microbial survival, and the deposition of …
Published in International Journal of Atmosphere · Vol. 3, Issue 1, 2026 · pp. 1–14 Read article