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182 articles for “Prevention mechanisms”
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Harnessing Nature: Formulations for Colon Cancer Prevention and Treatment
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Role of Fatigue and Creep in Structural Damage: A Comprehensive Review
Abstract: Fatigue and creep are two critical degradation mechanisms that significantly influence the structural integrity and longevity of engineering materials. These phenomena arise due to different loading and environmental conditions but often coexist in various industrial applications, leading to severe material degradation over time. Fatigue primarily results from cyclic loading, where repeated stress variations induce microstructural damage and crack initiation, ultimately causing catastrophic failure. Conversely, creep occurs under sustained stress at …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 1, 2025 · pp. 22–26 Read article
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Hybridization Method for Injection Moulding Process, Optimization with Melting Temperature Parameters
Abstract: Due to the production of plastic products with complex shapes, the plastic injection moulding manufacturing method has recently received a lot of attention. In order to improve manufacturing performance, the cycle time for the injection moulding process has been reduced, the defect known as dimensional warpage that results from temperature differences inside the mould has been reduced, and the mechanical tensile strength of the material has been increased so that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 337–345 Read article
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Challenges in Parallel Computing for Big Data Analytics
Abstract: The integration of parallel computing into the realm of big data analytics promises accelerated processing speeds and enhanced scalability, but it is not without its formidable challenges. This study explores the multifaceted hurdles faced in the pursuit of efficient parallel processing for large-scale data analytics. The intricate task of distributing and partitioning massive datasets across multiple processing units demands adept strategies to ensure equitable workloads. Load balancing emerges as a …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 1, 2024 · pp. 1–6 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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Differential Model of Wave Vibration on Strings and Rods
Abstract: Vibration, as a physical phenomenon, plays a multifaceted role in both natural and engineered systems. Beyond its essential contribution to communication through sound and speech, it finds critical application in various technological domains. For instance, in the design of stringed musical instruments such as violins and guitars, precise manipulation of string vibrations defines tonal quality and musical resonance. Similarly, metal rods in tuning forks exhibit vibrational properties that are finely …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 17–21 Read article
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The Decision of the Maximum Synchronous Torque During the Solar Array Deployment Using the Closed Cable Loop
Abstract: It was a long time since mankind explored and studied the universe, but the early-age power sources have not changed a lot over that period. Solar panels have been used long ago and are still in use today. However, their efficiency has improved considerably. Large and complicated solar arrays are now used instead of simply attaching the panels directly on the face of the satellite. A solar array is essential …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 37–49 Read article
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Emerging Trends in Photobiology: Exploring the Photophysics and Photobiology of the Eye
Abstract: The eye consists of three main segments: the cornea, lens, and retina. The primary function of the anterior ocular tissue, the cornea and lens, is to transmit and focus light onto the retina without distortion. They also filter UV light (under 400 nm), preventing it from reaching the retina. While light reaching the retina is mostly used for vision, it can also have various effects on the eye's constituents, both …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
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Enhancing Patient Safety: A Study On Adr Monitoring In Tertiary Care Hospitals
Abstract: Background: Adverse drug reactions (ADRs) are a major concern in healthcare, causing patient morbidity and mortality. The objective of this study was to investigate the adverse drug reactions in a tertiary care hospital. Methods: From January to July 2024, an observational study was carried out at Bangalore's Akash Super Specialty Hospital. 51 individuals had their demographics, medications, and suspected adverse drug reactions (ADRs) gathered. The Naranjo scale was used to …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 1–7 Read article
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Study of an Improved Quantum Particle Swarm Optimization-Based Framework for Neural Network Optimization in Modelling of Polymer Data
Abstract: The accurate forecasting of polymer viscosity at various physicochemical conditions has been quite critical due to the nonlinear interactions and interrelations between the variables. This paper suggests a better hybrid modelling framework, which involves the use of Artificial Neural Networks (ANN) and more advanced versions of Quantum Particle Swarm Optimization (QPSO) to better predict polymer viscosity. The input parameters taken are, namely, log (shear rate), polymer concentration, NaCl concentration, Ca …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Perspectives on ‘Kamsaharitaki’: an Ayurvedic Formulation for COVID-19 related Multisystem Inflammatory Syndrome (MIS)
Abstract: Background and Aim: Angiotensin-converting enzyme 2 receptor (ACE2), together with Transmembrane protease serine 2 (TMPRSS2), is a protein receptor for SARS-CoV-2 virus in the host subject; expression of ACE2 and TMPRSS2 reveals the multidimensional character of COVID-19 infection. SARS-CoV-2 Prominently induces pulmonary and systemic injury with other synergistic mechanisms. Preexisting chronic inflammatory conditions markedly sustain and aggravate the severity and cytokine storm. Inflammatory responses are closely linked with COVID-19 severity …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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A Study to Assess the Effectiveness of Body Mechanics Training Programme on Reducing Low Back Pain Among Nursing Officers Working in Selected Hospitals, Bangalore
Abstract: Background: Low Back Pain (LBP) is a common work related injury and costly problem among the nursing profession. Numerous studies indicate a greater occurrence of back pain and work-related back injuries among nursing officers in comparison to other occupations. Prevention of LBP is a very important technique to maintain proper body mechanics. This study aimed to assess the effectiveness of body mechanics training programme on reducing low back pain among …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 29–62 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Agribot: Arduino controlled Automatic seed sowing machine for small scale cultivation.
Abstract: The Agribot is a robot that reduces the efforts and total cost of sowing the seeds. A seed Sowing Machine should be suitable for all farms, have robust construction, also it should be reliable, this is the basic requirement of a sowing machine. Thus, we made a seed-sowing machine that is operated manually but reduces the efforts of farmers thus increasing the efficiency of planting and also reducing the problem …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 23–29 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Application-Driven Rule-Based Framework for Lubrication Failure Modes in Industrial Systems
Abstract: Modern lubricants increasingly rely on polymer-based composites, integrating synthetic base oils, polymer thickeners and solid additives like MoS₂ and PTFE for high-performance applications. These formulations not only enhance thermal and mechanical stability but also enable low-friction operation across diverse industrial conditions. Lubrication-related failures represent a critical cause of unplanned downtime and reduced reliability in industrial machinery. This paper presents an application-driven, rule-based framework designed to assess and mitigate lubrication failure …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 522–531 Read article