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179 articles for “Phytochemical compound”
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The Role of Quercetin, Curcumin, Eugenol, and Andrographolide in COVID-19 Treatment: A Review of Their Mechanisms of Action and Clinical Efficacy
Abstract: The world has recently experienced the covid diseases. It became the global worry with no remedy initially. Later, different antiviral medications in the form of injections and nasal sprays began to be employed. Many studies have been conducted to determine the antiviral effects of phytochemical substances. The corona virus's spike protein interacts with the ACE2 receptors on the alveoli's surface to enter the cell. After that, the polyprotein is transformed …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 1, 2023 · pp. 27–38 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
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In-silico screening of phytochemicals for identification of an alternative therapy for thyroid cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Preliminary Phytochemical Screening from Different Extracts of Bryonopsis laciniosa Fruits
Abstract: Plants derived bioactive compounds have been the focus of recent research due to their health promoting effects. There is continuous and urgent need to discover new antimicrobial, antioxidant and anticancer compounds with diverse chemical structures and novel mechanism of action because there has been an alarming increase in the incidence of new and re-emerging diseases. The present investigation was carried out to assess the qualitative phytochemical analysis of Bryonopsis laciniosa …
Published in Research & Reviews : Journal of Herbal Science · Vol. 5, Issue 2, 2016 · pp. 25–29 Read article
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Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study
Abstract: Plant extracts or secondary metabolites have served as antioxidants in phytotherapeutic medicines to protect against various diseases for centuries. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables and roots that have defence mechanism and protect from various diseases. Phytochemicals are primary and secondary compounds. Chlorophyll, proteins and common sugars are included in primary constituents and secondary compounds include terpenoids, alkaloids, quinines, flavonoids, sterols, saponins, tannins and phenolic compounds. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 3, 2016 · pp. 30–39 Read article
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Phenolic Compound Extraction from Leaves of Nyctanthesarbor-tristis
Abstract: Nyctanthes arbortristis is known as night-flowering jasmine and belongs to Oleaceae family. It is a fragrant white flowering shrub that is medicinally useful, sacred, and ornamental plant species. It is commonly grown in garden areas due to its pleasant fragrance and unique. The plant also growing on rocky areas in dry hillshades and is tolerant of moderate shade. It contains several phytochemicals like phenolic compound, flavonoids, tannins, alkaloids, saponins and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 12, Issue 2, 2021 · pp. 72–76 Read article
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Antifungal, Antioxidant Activity and Phytochemical Analysis of Extracts from Vitex rivularis (Lamiaceae)
Abstract: The present study was designed to investigate the biological properties of methanolic extracts of leaves and seeds from Vitexrivularis. Leaves and seeds extracts were prepared by maceration in methanol. Phytochemicals analysis was performed by colorimetric method, chemical reaction method and high-performance liquid chromatography (HPLC). The broth microdilution method was used to evaluate the in vitro activity against three strains of Candida albicans and 17 isolates of two yeast species (Candida …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 23–48 Read article
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Assay of the Antitrypanosomal Activity of Ziingiber Officinale Extract in Wister Rats
Abstract: This research investigated the antitrypanosomal effects of Zingiber officinale in rats infected with Trypanosoma brucei brucei. Twelve adult rats, 7 weeks old and of both sexes, were randomly divided into six groups (1 through 6), with each group consisting of two rats. All six groups (1–6) were intraperitoneally injected with 0.1 ml of blood containing 10⁶ Trypanosomes/ml. Groups 1–4 received daily intraperitoneal doses of the plant extract at concentrations of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 32–37 Read article
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Studies on Extraction and Purification of Total Phenolic Content from Methanolic Extract of Syzygium Cumini Seeds
Abstract: Syzygium cumini is commonly known as Jamun fruit and belongs to Myrtaceae family. It contains various nutritional values like sugars, vitamins, lipids, carbohydrate content, organic acids, minerals. Mainly this seed contains various phytochemicals like phenolic compounds (gallic, ferulic, caffeic), flavonoids (quercetin, rutin, kaempferol), carotenoids (β-carotene, γ-carotene, lycopene) and other compounds are present. This seed also shows pharmacological properties like antioxidant, antimicrobial, anti-inflammatory, antimutagenic, enzyme inhibitory and tonic effects etc. In …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 2, 2022 · pp. 8–12 Read article
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Formulation and Evaluation of Aqueous Azadirachta indica Phytosome
Abstract: A phytosome is a complex created through the union of a natural compound, typically a plant extract, with a phospholipid. Phospholipids play a crucial role in cell membranes, possessing a structure comprising a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tails. This distinctive structure enables phospholipids to construct lipid bilayers, fundamental elements of cell membranes. Phytosome increases the bioavailability, and absorption of active chemical constituents in the extract with the help …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 17–30 Read article
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A Review on Cucurbita
Abstract: Cucurbita species is a good nutritional vegetable species and belongs to cucurbitaceae family. It is commonly grown throughout the world. It’s appearance is of green and yellowish-orange color. It contains so many nutritional values like proteins, fatty acids, carbohydrates and phytochemical constituents like phenolic compounds, flavonoids, tannins, etc. It shows so many pharmacological activities like anti-oxidant, anti-inflammatory, anti-cancer, anti-ulcer, anti-diabetic activities, etc.Keywords: Pumpkin, phytochemicals, anti-diabetic, nutrition, gallic acidCite this ArticleAman …
Published in Research & Reviews : Journal of Botany · Vol. 7, Issue 3, 2018 · pp. 15–16 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Extraction of Phytochemicals from Leaves of Hibiscus rosa sinensis
Abstract: Hibiscus rosasinensis is medicinal and ornamental plant species belongs to Malvaceae family. It contains various phytochemical constituents like phenolic compounds, flavonoids, tannins, alkaloids, saponins etc. Hundreds of chemical compounds are synthesised in different parts of the plant including flowers, stems, roots and leaves etc. that have numerous medical and pharmacological applications. Leaves are used to treat blood vessel hypertension, fatigue, depression and skin problems. It shows various medicinal properties like …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 3, 2020 · pp. 9–11 Read article
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Studies on Phytochemical analysis of Citrus sinensis
Abstract: Citrus sinensis, also known as sweet orange, is an extensively grown fruit with extensive nutritional and medicinal significance. The present study focussed on the phytochemical analysis of C. sinensis, aiming to identify and quantify the bioactive compounds present in its various plant parts. The investigation encompassed the extraction, isolation, and characterization of secondary metabolites, including flavonoids, alkaloids, terpenoids, phenolic compounds, and essential oils. The research employed a combination of classical …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 3, 2023 · pp. 9–14 Read article
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A Review on Pharmacological Activities of Oldenlandia Auricularia
Abstract: Oldenlandia auricularia is a medicinal plant, which is originated from South India, Australia, Malaysia, Philippines and Sri Lanka. It also grows in open forest and shrubs. The plant belongs to the Rubiaceae family. The species comprises of around 1,300 varieties. There are several chemical compounds in the plant that have distinct pharmacological characteristics. Alkaloids, anthroquinone, iridoids, sugars, glycosides, coumarin, fatty acids, flavonoids and phenolic compounds are among the phytochemicals found …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 1, 2022 · pp. 11–18 Read article
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Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
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Phytochemical Characterization and Antimicrobial Activity of Cassia Alata Leaf Extract
Abstract: Aim: The aim of this study was screening for bioactive compounds with pharmaceutical properties from Cassia alata leaf extract. Methodology: The dried sample of Cassia alata leaf was powdered and extracted with ethanol using soxhlet apparatus. Antimicrobial activity of the leaf extract was checked against different clinical pathogens. Result and discussion: Thin layer chromatography (TLC) revealed the number of compounds present in the leaf extract. The results suggest that they …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 3, 2019 · pp. 20–24 Read article
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Phytochemical Screening and Structural Elucidation of Extracts from Garcinia kola (Heckel) Seeds
Abstract: This study evaluated the bioactive components of G. kola seeds extract to further establish its medicinal potentials. Extracts were obtained using different solvents thus; ethanol, methanol, ethyl acetate, acetone, cold and hot water. Phytochemical (quantitative) screening showed that saponins, flavonoids, terpenoids, tanins, glycoside and alkaloids are present in the G. kola extracts: however, the quantities vary with regards to the extraction solvent used. The highest quantity of phenols (35.63±0.06 mg/g) …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 23–27 Read article
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Ethnomedicinal, Pharmacological and Phytochemical Screening of Supari (Areca catechu Linn.): A Review
Abstract: Supari (Areca catechu Linn.) is a tall tree about 10–20 m long. It is used both locally and internally. Local application is beneficial in various acute inflammatory conditions in the form of gargle, vaginal douche or abzan, decoction, juice and oil. Internally it act as muqavvie-qalb (cardiotonic) and muqavvi-e-ama (intestinal tonic), sozish meda (gastric irritation), dries the excessive secretions of mouth, used in vomiting and nausea, strengthen the teeth and …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 6–20 Read article