Search
206 articles for “ACE 2”
-
Comparison of Prescribing Pattern of Anti-hypertensive Drugs and the Level of Control Achieved in Type 2 Diabetes Patients between Primary and Tertiary Care Hospitals
Abstract: Hypertension is a common co-morbidity of diabetes affecting majority of people with diabetes, also a major risk factor for coronary vascular disease and microvascular complications such as retinopathy and nephropathy. To compare prescribing pattern of anti-hypertensive drugs and the level of control of hypertension achieved in type 2 diabetes patients in primary and tertiary care hospitals. Fifty patients each with type 2 diabetes and hypertension (fulfilling JNC 7 criteria for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 2, 2014 · pp. 1–4 Read article
-
Quantitative Determination of Isomeric Components of essential oils by RP-HPLC-PDA in multi-herbal tablets
Abstract: Essential oils are lipophilic and highly volatile secondary plant metabolites, principally mono- and sesquiterpenes. The widespread usage and applications in biopharmaceutics and cosmoceutics of these components drives their quality assessments criteria to be established. Gas chromatography is one of the predominantly used technique for analyzing volatile oils. Although Gas Chromatography employs estimation designs operated at elevated temperatures leading for plausible structural alterations of thermo labile compounds. Hence, a novel gradient …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 19–28 Read article
-
Neutralization of Inflammatory Effect of LPS by Premna latifolia Extract in RAW 264.7 Cells
Abstract: Natural compounds of Premna latifolia, extracted using petroleum ether, ethyl acetate and methanol as solvent has dose-dependent effect against inflammatory effect of lipopolysaccharide (LPS) in RAW 264.7 cells. Keywords: Premna latifolia, inflammation, petroleum ether, ethyl acetate, methanolCite this ArticleDevi A. Neutralization of inflammatory effect of LPS by Premna latifolia extract in RAW 264.7 cells. Research & Reviews: Journal of Herbal Science. 2018; 7(3): 1–3p.
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 3, 2018 · pp. 1–3 Read article
-
Mechanistic and Catalytic Behavior of Os(VIII) for the Chlorpheniramine Maleate and Bromamine-B Redox System: A Kinetics Based Approach
Abstract: Chlorpheniramine maleate (CPM) is an important antihistamine agent. To the best of our knowledge there is no report in the literature about the oxidation of CPM with halogen + 1 oxidant from the stand point of its kinetics and mechanistic chemistry. Hence, a systematic kinetics and mechanistic study on the oxidation of CPM with bromamine-B (BAB) in the presence of NaOH and Os(VIII) catalyst has been carried out at 303 …
Published in Journal of Catalyst & Catalysis · Vol. 2, Issue 1, 2015 · pp. 18–31 Read article
-
“High Melatonin Milk”- Milk with Intrinsic Health Benefit
Abstract: Melatonin C13H16N2O2 (molecular weight: 232) or N-acetyl-5-methoxytryptamine, is chemically an indoleamine and derived from the essential amino acid tryptophan. It is a hormone and due to secretion from pineal gland, it is also called as active pineal factor. Its IUPAC name is N-[2-(5-methoxy-1H-indol-3-yl)ethyl] acetamide. The indole ring acts as the chromophore showing maximum absorbance at 223 nm, and the functional groups contribute to its fluorescence property. Lerner et al. 1959 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 13–16 Read article
-
Synthesis, Characterization and Antibacterial Activity of Chalcone Derivatives
Abstract: Chalcone derivatives were produced by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. Chalone derivatives are valuable species as they belong to keto-ethylenic components. Chalcone is a one-of-a-kind template that is linked to a variety of biological processes. 2-hydroxy-2,5- dichloro acetophenon (1) were synthesized by Fries migration and condensed with aromatic aldehyde to produce the new chalcone derivatives (2a-e). The new 1-(2-hydroxy-3,5-dichlorophenyl)-aryl-prop2-ene-1-ones (2a-e) (chalcones) were characterized using FT-IR and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 14, Issue 2, 2023 · pp. 42–46 Read article
-
A Machine learning approach to asses carbon emission, utility to produce biomaterial
Abstract: The transportation sector, and the automotive industry in particular, has grown significantly over the last ten years. However, these quick advancements have also brought about important problems that require workable answers. The problem of carbon emission is responsible for global warming due to greenhouse gas emission. The present work is focused on CO2 emission from public and personal transport within Agra city on a real-time basis. In the context of …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 22–30 Read article
-
Development and Validation of HPLC Method for Simultaneous Estimation of Cilnidipine and Valsartan in Bulk and Tablet Dosage Form
Abstract: A simple, sensitive, accurate and precise reverse phase high performance liquid chromatographic method has been developed for the simultaneous estimation of Valsartan and Cilnidipine. The purposed RP-HPLC method utilizes stationary phase and consists of symmetry C18 (250 × 4.6 mm, 5 μm in particle size) with a mobile phase comprising of Acetonitrile: Ammonium Acetate Buffer (75:25%v/v) pH 5.0 adjusted by Triethylamine at a flow rate of 1.0 mL/min, column temperature …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 2, 2015 · pp. 28–36 Read article
-
Partial Characterization of Crude Lipase from Mutant Soil Fungal Isolate
Abstract: Lipases are cluster of enzymes which cleaves oils and fats. Characterization properties oflipases have been studied in the present investigation because they play an imperative role inseveral industrial applications. The present lipase obtained from soil fungal strain named asEMS5%-60min exhibited optimum activity at pH 7.0 (24.90±0.25 IU/ml/min) and 37ºC (20.28±0.51IU/ml/min). In pH stability profile, the enzyme was found stable in alkaline pH range withhighest activity (13.08±0.07 IU/ml/min) at pH 9.0. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 79–89 Read article
-
Antibacterial, Cytotoxicity Studies of Azukia mungo (L.) Masam and Correlation with in silico Docking Studies
Abstract: Introduction and Background: Azukia genus plants rich in proteinaceous anti-nutrients like tannins (especially condensed tannins) has been shown to have anti-bacterial activity against Staphylococcus aureus and antineoplastic activity against lung and liver cancer cells. Five types of procyanidins (condensed tannins) have already been isolated from Azukia mungo and structurally elucidated. But its activity against the Methicillin resistant Staphylococcus aureus (MRSA) has not yet been shown. Hence we focus our work …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 2, 2017 · pp. 21–31 Read article
-
Synthesis, Characterization and Antibacterial Activity of Mono- and Binuclear Co(II) and Cr(III) Mixed-Ligand Complexes Derived from α-Amino Acid and 1,10- Phenanthroline with 1,3-Diaminopropan as a Spacer
Abstract: Mixed-ligand complexes of Co(II) and Cr(III) ions were synthesized from the reaction of metals chloride salts with α-amino acid (H2L1) as a primary ligand and 1,10-phenanthroline (L2) as secondary ligand. The ligand 2-(benzo[d]thiazol-2-ylamino)-2-(2-hydroxynaphthalen-1-yl) acetic acid (H2L1) has been synthesized from the condensation reaction of inobenzothiazol with 2-hydroxy-1-naphthaldehyde in the presence of HCN as three components–one pot reaction. H2L1 considered as a tridentate chelater of ONO-coordination binding type toward the metals, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 107–120 Read article
-
Immunologic Characteristics of Apparently Healthy Nigerians Exhibiting Abnormal SPE: A Preliminary Study
Abstract: Abnormal serum protein electrophoresis patterns have been discovered in apparently healthy Africans in Britain and Ghanaians living in Accra, Ghana. Conflicting reasons were suggested for this phenomenon. The aim of present study was to determine the prevalence and characteristics of serum protein electrophoresis (SPE) abnormalities in apparently healthy Nigerians living in Ogbomoso. Three hundred (300) apparently healthy subjects aged 20–30 years were selected for the study. SPE was performed on …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 1–6 Read article
-
Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System
Abstract: Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography. Keywords: Derivatization, amino acid, chiral reagent, HPLCCite this Article Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 39–43 Read article
-
Antibacterial Activities of Medicinal Plant Leaves Extract Against Isolated Escherichia coli Bacteria from Different Water Sources
Abstract: Objective: Escherichia coli are the most common pathogenic bacteria to accountable for food and waterborne illness. Therefore, in this way the study was conducted to resolve the occurrence of E. coli bacteria from different water sources in around Tamil Nadu along with to determine their antibiotic resistance profiles. Methods: Water samples were analysed for the presence of E. coli bacteria using specific agar media Eosin Methylene Blue and McConkeys. Colony …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 34–40 Read article
-
In Silico Molecular Docking Studies of Phytoconstituents Identified in Curcuma zedoaria Rosc. on Acetylcholinesterase: An Enzyme Target for Anti Alzheimer’s Activity
Abstract: Alzheimer’s disease (AD) is a chronic, progressive and disabling organic brain disorder characterized by disturbances of multiple cortical functions. Acetylcholinesterase (AChE) inhibition is thought to be a promising approach towards the treatment of AD. The aim and objective of the present study is to perform in-silico docking analysis of the major active constituents identified in Curcuma zedoaria Rosc. against AChE for anti-Alzheimer’s activity. In this perspective, phytoconstituents like bisdemethoxy curcumin, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 9–14 Read article
-
Intralesional Injection of Triamcinolone Acetonide Effectively Reduces the Post-traumatic and Post-surgical Fibrosis
Abstract: Intralesional injection of triamcinolone acetonide is commonly used to resolve partially or completely the keloid and hypertrophic scars in the human. This study aimed to show the effect of two successive intralesional injections of triamcinolone acetonide into the fibrous band followed a surgical intervention or trauma in the faciomaxillary area. Its effect was assessed by improving the mouth opening and closing the eye. A total number of 21 (14 males …
Published in Research and Reviews: A Journal of Dentistry · Vol. 11, Issue 1, 2020 · pp. 18–23 Read article
-
Characterization of Mn Dopped SrAlO Nano-Phosphors Prepared via Sol-Gel Method
Abstract: Strontium aluminate with Mn dopped phosphor was synthesized by Sol-Gel method using Strontium Acetate, Aluminium Acetate as raw material and 2-methoxyethanol as complexing agent. The transparent sol was preheated at 100°C for 2 h and then the precursor was finally annealed at 950°C for 2 h. The phosphor emits luminescence with peak wavelength at 395 nm and 520 nm under near-ultraviolet excitation at 360 nm. The morphology, composition and structure …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 6, Issue 3, 2016 · pp. 5–10 Read article
-
Chemical Composition and Toxicity Profile of the Essential Oils of Bosqueia angolensis Ficalho and Berlinia grandiflora (Vahl) Hutch & Dalziel
Abstract: The chemical composition of the essential oils obtained from the leaves and stem bark of Bosqueia angolensis (Moraceae) and Berlinia grandiflora (Fabaceae) using hydrodistillation were analysed using Gas Chromatography–Mass Spectrometry (GC-MS) techniques. The percentage yields of the essential oils are: B. angolensis leaves (0.53%), B. angolensis stem bark (0.49%), B. grandiflora leaves (0.45%) and B. grandiflora stem bark (0.51%). A total of 10 and four compounds representing 84.3% and 96.1% …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 2, 2018 · pp. 15–20 Read article
-
Antidiarrheal Activity of Leucaena Leucocephala in Castor Oil Induced Diarrhea in Albino Rats
Abstract: The purpose of the present study was to evaluate scientifically the anti-diarrheal effects of different extracts of leaves of Leucaena leucocephala. Different extracts of Leucaena leucocephala like petroleum ether, chloroform, and ethyl acetate were studied against castor oil induced diarrhea model in albino rats. The weight of the fecal matter induced by castor oil induced diarrhea was recorded as the chief parameter. Standard drug loperamide (1 mg/kg, i.p.) showed highly …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 1, 2020 · pp. 8–12 Read article
-
Lattice Parameter and Grain Size of Hydroxyl apatite of Enamel that Exposured by Sunti Acid (Averrhoa bilimbi l)
Abstract: The structure of Hydroxyl apatite (HA) were changed by acid exposure both in the core and crystal wall in 180 min. Sunti acid (Averrhoa bilimbi l) is one of the most popular traditional foods in Aceh that has a pH 2.1 that could improve the structure of HA. Nanostructure change of the HA ultimately affect the strength and macro structure of tooth enamel. The objective of this study is to …
Published in Research and Reviews: A Journal of Dentistry · Vol. 2, Issue 1-3, 2011 · pp. 39–44 Read article