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543 articles for “(DoS)”
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Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article
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Optimal Dosage of Pumice in Lightweight Aggregate based Conc
Abstract: Lightweight concrete (LWC) is a pioneering solution in the construction sector, characterized by its unique composition and versatile applications. Engineered with lightweight aggregates and additives, LWC achieves a significant reduction in dry density compared to conventional concrete, making it 23% to 87% lighter, with densities ranging from 300 to 1,840 kg/m³. This reduced weight makes LWC ideal for projects requiring load minimization, such as high-rise buildings and prefabricated elements. A …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 23–32 Read article
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Fault Dealing through Software Fault Tolerance in Automated Dose Packaging System
Abstract: Each industry is highly influenced by latest computer technology. Computer system has quickly become an important and vital element in any growing industry. Each industry is depending on certain computer base applications and systems to achieve high accuracy and reliability. This paper focuses on automated dose packaging system. Such system needs supportive computer system which assists to have desired outcomes at any circumstances. Faulty environment may cause unexpected damage to …
Published in Journal of Computer Technology & Applications · Vol. 9, Issue 1, 2018 · pp. 1–5 Read article
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High Doses Biotin beyond Its Nutraceutical Prescription: Update Indications for Neurological Diseases
Abstract: Biotin or vitamin H is ubiquitous B-complex vitamin that plays as a co-factor in different metabolic process in the body. The usual recommended daily requirement is 30µg. Recent studies found biotin in high doses involved in the synthesis of myelin in patients with multiple sclerosis. The Med Day Pharmaceuticals launched an oral formulation of biotin high dose (Cerenday 100 mg capsule) and recommended for multiple sclerosis. Previous studies demonstrated the …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 2, 2017 · pp. 13–20 Read article
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Effects of a Single Dose Inhalation of Ipratropium Bromide, Salbutamol, Salmeterol, Beclomethasone, Budesonide in Stable Chronic Bronchitis: Comparative Study
Abstract: Chronic bronchitis usually treated with long acting bronchodilators and inhaled corticosteroids as monotherapy or in combination. The aim of this study is to assess the efficacy of single dose of β2-agonist (short and long acting), muscarinic antagonist and inhaled corticosteroids on the pulmonary function test in clinically stable chronic bronchitis patients. A total number of 93 (61 males and 32 females) patients who fulfilled the criteria of uncomplicated chronic bronchitis …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 12–17 Read article
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Activity Quantification of Lu-177 SPECT/CT Imaging for Calibration Factor Analysis in Clinical Radionuclide Dosimetry
Abstract: Purpose: To evaluate the calibration factor (CF) at three-time points with the same protocol & acquisition parameters for the images of Lu-177 activity, scanned by two different SPECT/CTs (GE & MEDISO) using a cylindrical Jaszczak phantom with cold inserts, filled with uniform activity in water and to analyze the changes in the calibration factor data with time. The purpose of the study is to quantitatively analyze the first step (calibration …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 9–22 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Form
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Revolutionizing Drug Delivery: Recent Advances in Pharmaceutical Dosage Forms
Abstract: Recent advances in pharmaceutical dosage forms revolutionize drug delivery, prioritizing targeted therapy and patient well-being. Enhanced drug carriers address complex medical challenges, from high-grade gliomas to ocular drug delivery, maximizing therapeutic efficacy while minimizing adverse effects. Traditional dosage forms like tablets and capsules undergo meticulous formulation and manufacturing processes, integrating Quality by Design principles for consistent product quality. Liquid formulations encounter stability challenges, necessitating rigorous stability testing and pH monitoring. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 77–89 Read article
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Simultaneous Determination And Stability Indicating Method For Telmisartan, Metoprolol Succinate And Cilnidipine In Tablet Dosage Form.
Abstract: There are several medicinal agents available for antihypertensive activity. Telmisartan, metoprolol and cilnidipine are among them. Quantitative and qualitative analysis plays a pivotal role in safeguarding patients. Here, the estimation of these drugs was performed by using the chromatographic technique RP-HPLC. It was conducted with Phosphate buffer (pH 3.5 ± 0.01): Methanol (50:50 v/v) mobile phase. The system was operated at 1 ml/min. Drug volume to the system was 20μl. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 32–38 Read article
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IoT Operated Pillbox for Old Age Persons to Remember the Medicines Dosages
Abstract: In today's fast-paced world, remembering to take medications on time can be a real challenge. Missing doses can have serious consequences for health and well-being. To combat this issue, we can leverage the power of Internet of Things (IoT) to create a smart pill box that ensures timely medication adherence. This study will guide researchers through building a simple yet effective IoT-operated pill box using an Arduino Nano, a buzzer, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 2, 2025 · pp. 20–32 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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COMPOSITION, RADIATION DOSE AND TEMPERATURE DEPENDENT DEGRADATION STUDIES OF POLYAMIDE 6 HOMOPOLYMER AND COPOLYMERS
Abstract: Composition radiation dose temperature dependency on free radicals generated in PA6, PA6/ PA12 copolymer, has been investigated by electron spin resonance (ESR) and FTIR techniques. ESR spectra of -irradiated PA6 has shown complex shaped and number of hyperfine lines is observed to be in between 6-10. This complex spectrum is assigned to macro-radicals of the type ~CH2CHCH2~, which in principle has to give a ten line ESR spectrum. However, due …
Published in Journal of Catalyst & Catalysis · Vol. 5, Issue 1, 2018 · pp. 25–37 Read article
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Prevention of Breakthrough Varicella and Outbreaks by Two Dose Vaccination
Abstract: Among viral infections, one of the known human herpes viruses, Varicella-Zoster Virus (VZV) causes latent infection. The VZV causes two distinct diseases, varicella (chickenpox) and after latency shingles (herpes zoster). Although safe and effective vaccine is available, it is not widely used in many geographic areas mainly because of non-inclusion in the routine immunization schedule. Over the years, many countries have reported more than 90% reduction in number of varicella …
Published in Research and Reviews : A Journal of Immunology · Vol. 4, Issue 3, 2014 · pp. 24–28 Read article
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Treatment of Generalized Eruptive Keratoakantoma Using Acitretin Dosage
Abstract: Keratoakantoma (KA) is a squamous neoplasia, variant of squamous cell skin cancer. In typical cases it is found to be solitary, filled with keratin, dome-shaped craterform papule with a diameter of 1–2 cm. KA regresses spontaneously within 3 months after the onset of the disease. Atypical KA persist, rarely regress spontaneously and can be giant, multinodular, centrifugum marginatum, subungual, as well as multiple, including Generalized Eruptive Keratoakantoma (GEKA). In the …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 27–32 Read article
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Development and validation of a method for simulataneous determination of tenovifir disoproxil fumarate emtriculabine and isonized in bulk and pharmaceutical dosage form using RP-HPLC with relevance to toxicological aspects
Abstract: Hence, proposed analytical methods are simple, novel, economical, rapid, sensitive, reproducible and accurate for the Simultaneous estimation of Tenofovir Disoproxil Fumarate, Emtricitabine and Isoniazid in Bulk and Phamaceutical dosage form by using RP- HPLC. This Method gives reliable assay results with short analysis time using mobile phase of Acetonitrile : 0.02M Potassium Dihydrogen Orthophosphate: water (pH 5.3) in the ratio of 60: 25: 15 respectively. Retention time was found to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 17–25 Read article
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Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
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A New Separation Technique for Method, Development and Validation of Aclidinium Bromide and Formoterol Fumarate in Its Pure and Pharmaceutical Dosage Form by Using Rp-HPLC
Abstract: A new simple, precise, selective and accurate, a new method of development and validation using Rp-HPLC for the estimation of Aclidinium bromide and Formoterol Fumarate in its pure and pharmaceutical dosage form. Chromatogram was run through DIKMA Spursil, C18 segment (4.6×150 mm, 5µ0). Mobile phases contain 0.1% OPA: Acetonitrile (30:70) with the use of the 0.1% OPA buffer, stream rate of 1 ml/min and measured in 280 nm. The run …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 18–36 Read article
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Effect of Different Doses of Phosphorus on the Growth and Yield of Mung Bean (Vigna radiata L.)
Abstract: Phosphatic fertilizers play a vital role in enhancing mung bean production by not only improving crop yield but also increasing the quality of the produce. A field trial was done at the Nepal Polytechnic Institute research field to determine the effect of different levels of phosphorus on yield of Mung bean at Bharatpur, Chitwan during the summer season 2024. The test was carried out as per Randomized Complete Block Design …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 2, 2025 · pp. 1–7 Read article
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Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
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Effect of Different Dosages of Saline Water on the Index and Engineering Properties of Bentonite
Abstract: The paper presents the effect of different dosages of saline water on the index and engineering properties of bentonite. The various tests conducted were consistency limits, free swell index, compaction and unconfined compressive strength. The saline water solution was prepared by varying the salt content from 5 to 40 gms per litre of distilled water. The specimens were prepared at their maximum dry unit weight and optimum moisture content. The …
Published in Journal of Geotechnical Engineering · Vol. 5, Issue 2, 2018 · pp. 1–7 Read article