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404 articles for “anal disease”
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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High-Definition Electroencephalography: A New Horizon in Neurological Pathology Research
Abstract: The advent of high-density electroencephalography (HD-EEG) has catalyzed a paradigm shift in the exploration of neurological pathologies. This editorial underscore its transformative potential in elucidating brain dynamics and refining diagnostic approaches for a spectrum of conditions, spanning from epilepsy and dementia to cognitive impairments in preterm infants. Our objective is to optimize the utility of HD-EEG by emphasizing the imperative for methodological homogenization and fostering collaborative endeavors. The remarkable spatial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 15–21 Read article
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Development of a Low-Cost Air Quality Monitoring System Using the MQ2 Sensor
Abstract: Air pollution is becoming a major environmental problem, especially in cities, due to the quick expansion of industry and the rise in car emissions. The air is contaminated with dangerous chemicals such as carbon monoxide, nitrogen oxides, and fine particles, which have a major negative influence on human health by raising the risk of heart and respiratory diseases. Because of their dense populations and heavy traffic, urban areas are particularly …
Published in Recent Trends in Sensor Research & Technology · Vol. 12, Issue 2, 2025 · pp. 9–15 Read article
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Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19
Abstract: The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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The Impact of Food Fortification on Health and Nutrition
Abstract: This comprehensive study explores the critical role that food fortification plays in enhancing nutritional outcomes and overall health. Through an extensive review of existing literature, this article explores the diverse ways in which fortifying foods with essential nutrients positively influences public health. This analysis encompasses the benefits of fortification by addressing micronutrient deficiencies, promoting overall well-being, and preventing various health conditions. Food fortification is a pivotal intervention in the realm …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Exploring the Development of AI Models Using Open-Source Tools to Predict Patient Outcomes and Optimize Treatment Plans
Abstract: Integrating artificial intelligence (AI) into healthcare offers a transformative opportunity to enhance patient care and clinical decision-making. Through the use of predictive analytics, AI can significantly enhance the accuracy of outcome predictions and assist in developing personalized treatment plans that cater to each patient’s specific needs. This paper delves into the development of AI models using open-source tools, which are increasingly favored for their accessibility, collaborative nature, and capacity for …
Published in Journal of Open Source Developments · Vol. 11, Issue 3, 2024 · pp. 37–49 Read article
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Assessing Taila Bindu Pariksha as a Diagnostic and Prognostic test for Diabetes Mellitus
Abstract: Ayurveda has consistently emphasised on not just treatment of a disease but also how to diagnose it and further assess the prognosis. Ayurveda is blessed with different diagnostic tests which is broadly classified into Roga and Rogi Pariksha such as Ashtavidha Pariksha, Dashavidha Pariksha and Dwadashavidha Pariksha. These tests are used very rarely by just few Ayurvedic practioners as an important diagnostic and prognostic methods in different diseases. Taila Bindu …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Computational Analysis of Non-Newtonian Blood Flow through Bifurcated Coronary Artery: Insights into Hemodynamics and Wall Shear Stress
Abstract: This abstract presents a study on the computational fluid dynamics (CFD) simulations of blood flow through a bifurcated coronary artery using non-Newtonian fluid model. The objective of this study is to investigate the hemodynamic characteristics in Bifurcated Coronary artery. The methodology involved the utilization of ANSYS SpaceClaim software for creating a geometric model of the bifurcated coronary artery. A mesh independent study was conducted to ensure the accuracy and reliability …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 160–168 Read article
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A Study to Assess the Nutritional Status of Kidney Failure Patients Undergoing Maintenance Hemodialysis
Abstract: Malnutrition is a common and serious complication among patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis (MHD) and is strongly associated with increased morbidity and mortality. The present study was conducted to assess the nutritional status of patients on maintenance hemodialysis and to identify factors contributing to protein-energy malnutrition in this population. A cross-sectional and follow-up assessment was carried out among patients receiving regular hemodialysis at a dialysis center. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 82–94 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Quality of Sleep Among Patients with Chronic Renal Failure
Abstract: Renal failure is the partial or complete impairment of kidney function. Inability to eliminate metabolic waste products and water, along with functional disruptions in all bodily systems, result in the condition known as renal failure. Renal failure can be categorized as either acute or chronic. Chronic renal failure refers to the gradual and irreversible deterioration of the nephrons in both kidneys. It is characterized by either kidney damage or a …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 22–28 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Mid-Year Epidemiological Profile of COVID-19 Posi ve Cases in Rajasthan, India
Abstract: Background: COVID-19, caused by SARS-CoV-2, has posed persistent public health challenges globally since its emergence in late 2019. India, through enhanced surveillance and vaccina on, has seen a progressive decline in case burden. Despite improvements, localized surges and emerging variants necessitate con nuous monitoring. Rajasthan, with its urban-rural health dispari es, experienced a modest resurgence of cases in early 2025, raising concerns about exis ng immunity gaps and health system …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Bioactive Compounds in Ethanolic Extract of Strychnos innocua Root Using Gas Chromatography and Mass Spectrometry (GC-MS)
Abstract: Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which can discharge numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial, and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in the ethanolic …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 9–14 Read article
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Autonomous Infection Control System
Abstract: Escalating problems arise mainly at hospitals due to transmission of microbes through air, which causes life threatening situations. Doctors, nurses and other members are more vulnerable to diseases from within the place. PPE kits and other disinfecting procedures require an in-human presence to do the work, which makes it more challenging and puts the person's life at risk. In current scenarios, human presence is required for sanitising and cleaning procedures, …
Published in Journal of Mechatronics and Automation · Vol. 11, Issue 2, 2024 · pp. 12–18 Read article
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Dr. Somenath Dutta, Discoverer of Micro-RNA (MiRNA) Therapeutic to Prevent Harmful Zika Virus for Liver Cancer: A Scientometric Portrait
Abstract: Dr. Somenath Dutta allies Rahul is a global recognized scientist for his outstanding recent discovery of “miRNA therapeutics for the Zika virus” at the age of 26 years, which can be cured Liver Cancer and allied health problems due to Zika virus disease. This study covers his 12 publications in variety of forms including 07 journal articles (59%), 03 conference papers (25%), 01 dissertation, and 01-chapter paper during 2019-2024. All …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 22–36 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Assessment of the Post-Harvest Chicken Egg Handling Practices in Gamo and Konso Zones of South Ethiopia
Abstract: The study was conducted starting from September to December 2024 in two districts of South Ethiopia with the objective of assessing the prevailing post-harvest chicken egg handling practices, storage materials, duration of storage, and marketing in the rural household. An aggregate of 120 family units were selected randomly from selected peasant area and interviewed by pre-tested questionnaires. The collected data were analyzed by Statistical Package for Social Sciences (SPSS, 2010) …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 61–69 Read article