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508 articles for “Anti – infective”
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Control of Powdery Mildew of Sheesham (Dalbergia Sissoo) in India through Radionics Computer and Nanotechnology from Kuwait
Abstract: Powdery mildew is a common fungal disease caused by different fungi on different hosts including field crops, vegetable crops, fruit trees, ornamentals, and woody trees. Sheesham (Dalbergia sissoo) is one of the most common and important timber and woody trees in the Indo-Pak subcontinent. An experiment was conducted to control the growth/spread of powdery mildew caused by the fungus (Phyllactinia dalbergiae) growing on ‘Sheesham’ (Dalbergia sissoo) tree leaves. The infected …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 106–113 Read article
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Vaccination—A Novel Agent Against Bacterial Drug Resistance
Abstract: Increase in the mortality and morbidity due to infection has been on rise due to the presence of multidrug resistant organisms. Several mechanisms have been evolved to overcome the effect of multidrug resistance of bacteria including antibacterial stewardship programs. Recently the application of vaccination has been seen as a tool against bacterial drug resistance. Keywords: bacterial drug resistance, vaccines, morbidity, mortalityCite this ArticleManderwad GP, Raj Kumar HRV. Vaccination—A novel agent …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 14–15 Read article
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HBsAg Prevalence and Determinant Risk Factors among Voluntary Counseling and Testing Clients Visiting Gondar Health Center, Northwest Ethiopia
Abstract: Globally, an astounding number of people are infected with HBV, HCV and HIV. Due to shared routes of transmission, HBV and human immunodeficiency virus co-infection is common and is an emerging concern in the clinical management of patients because of increased mortality, accelerated hepatic disease progression, and the frequent hepatotoxicity caused by hepatitis B virus. The aim of this study was to assess the prevalence and risk factors of HBsAg …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 2, 2015 · pp. 15–20 Read article
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A Study on accelerating threat of Emerging Infectious Diseases (EIDs) and imperative for a proactive, interdisciplinary Global Health Security Framework
Abstract: Emerging Infectious Diseases (EIDs) represent one of the most critical and persistent threats to global health security in the 21st century. Driven primarily by the synergy of unprecedented human encroachment into wild habitats, climate change-induced ecological disruption, accelerated international travel, and antimicrobial resistance, the frequency and severity of zoonotic spillover events are rapidly increasing. Traditional, reactive public health measures—focused on containment after an emergence—have repeatedly proven insufficient, leading to catastrophic …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 8–21 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Review on Neem Bark: A Unani Medicine
Abstract: Neem is a medicinal plant found in almost every region of India recognized for its medicinal and therapeutic uses. Although all parts of this plant possess medicinal value, the neem bark has been widely used by the Unani physicians to treat various ailments especially for wound healing, dental problems and infectious diseases. In phytochemical analysis various biologically active substances have been isolated showing its medicinal importance. Also in animal studies …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 8, Issue 1, 2019 · pp. 29–34 Read article
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Decoding the Mycobacterium tuberculosis–Macrophage Interplay: From Immune Defense to Pathogen Persistence
Abstract: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) and has been responsible for over one billion deaths worldwide over the past two centuries, remaining a major global health challenge despite advances in diagnosis and treatment. The barriers that make tuberculosis difficult to treat and eliminate are inextricably tied to its intracellular habitat. However, a research gap lies in understanding the molecular mechanisms of its survival and …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article
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Chitosan-based Polymer Composites for Antibacterial and Antiviral Drug Applications
Abstract: The natural substance chitosan is made from chitin. It is used a lot in medicine because it is safe for the body, breaks down naturally, and kills germs. To find out how chitosan-based polymer mixes could be used to make drugs that kill germs and viruses, this study looks into them. By reacting with the cell walls of bacteria, chitosan has been shown to kill bacteria and stop viruses from …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 609–620 Read article
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Aluminum Oxide Nanoparticle-Adjuvanted Pasteurella multocida B:2 Vaccine is Potent and Efficacious and is Able with Keyhole Limpet Hemocyanin as a Marker to Differentiate Infected from Vaccinated Animals (DIVA)
Abstract: Pasteurella multocida B:2 causes hemorrhagic septicemia (HS) in bovines in Asia. For effective implementation of HS control program in India, a safe and efficacious vaccine to provide long lasting protection and allow differentiation of infected from vaccinated animals (DIVA) has to be developed. The objectives of the present study were to develop HS-DIVA vaccine with a companion immunodiagnostic test using keyhole limpet hemocyanin (KLH) as a marker, and to improve …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 8–16 Read article
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Paediatric Epilepsy: Current Advances in Diagnosis and Management
Abstract: Paediatric epilepsy is one of the most common chronic neurological disorders of childhood, characterised by recurrent unprovoked seizures resulting from abnormal neuronal activity. Accurate diagnosis is essential and is based on a detailed clinical history, seizure semiology, neurological examination, and electroencephalography (EEG), with neuroimaging such as magnetic resonance imaging (MRI) used to identify structural abnormalities. Classification according to seizure type and underlying aetiology genetic, structural, metabolic, immune, infectious, or unknown—guides …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 53–68 Read article
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Effect of Dimethyl Sulfoxide Extract on Different Parts of a Medicinal Plant:Euphorbia hirta L. Against Escherichia coli and Staphylococcus aureus
Abstract: Euphorbia hirta has been widely used by tribal as traditional medicine in the treatment against infectious pathogens. Euphorbia hirta Linn. is a perennial herb belonging to the family Euphorbiaceae. It is a potent medicinal plant and has established its sedative and anxiolytic activity. It has analgesic, antipyretic, anti-inflammatory, antidepressant for blood pressure, antihypertensive and antioxidant properties. Effect of dimethyl sulfoxide extract on different parts (leaf, bud and stem) of Euphorbia …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 2, 2015 · pp. 30–33 Read article
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Monoclonal Antibody (mAb) Drugs in Cancer Therapy
Abstract: Monoclonal antibodies (mAb) are widely used in the diagnosis of diseases, detection of marker molecules and in therapy. The mAb drugs are increasingly used to treat hypersensitivity, autoimmune diseases, transplantation rejection and more importantly in cancer therapy. Although the application of mAbs in the treatment of infectious diseases is limited, the wide acceptance of these drugs in cancer therapy is remarkable. As of 2011, at least 11 FAB approved mAb …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 2, 2012 · pp. 6–10 Read article
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A Comparative Review on Abelmoschus palianus and Barleria mysorensis: Phytochemical Constituents, Pharmacological Potentials, and Ethnobotanical Significance
Abstract: Medicinal plants have long served as invaluable resources for treating human ailments, with countless species still awaiting scientific exploration and validation. Abelmoschus palianus and Barleria mysorensis are two such botanicals with rich ethnomedicinal heritage but limited pharmacological characterization. This review presents a detailed comparative analysis of these two species, examining their botanical descriptions, geographic distribution, traditional applications, phytochemical constituents, pharmacological properties, toxicological profiles, and therapeutic potential. Abelmoschus palianus, native to …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 7–13 Read article
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Role of Nanotechnology in the Diagnosis and Treatment of Waterborne Diseases
Abstract: Nanotechnology provides new aspects for the treatment and diagnosis of diseases using atomic scale engineering of materials. The size of nanoparticles is similar to that of most biological molecules and structures; therefore, nanoparticles can be useful for both in vivo and in vitro biomedical research and applications. At the same time, the unique dimension of nanoparticles empowers them with special capabilities to successfully deliver the drug at the desired site. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 4, Issue 1, 2014 · pp. 19–28 Read article
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An Insight to Epidemiology, Diagnosis and Treatment of COVID-19
Abstract: Abstract Since late December, 2019 an outbreak of a novel coronavirus disease was reported in Wuhan, China with severe acute respiratory syndrome (SARS). It is commonly known as COVID-19 means a disease caused by coronavirus and the first case was identified in 2019. The WHO declared the COVID-19 a global pandemic in March, 2020 because it affected more than 100 countries worldwide. In this review we summarize epidemiology, diagnosis and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 13–22 Read article
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A comparative study of the Therapeutic Stratergies used in the treatment of Covid-19
Abstract: In late December 2019, an outbreak of an emerging disease (COVID-19) due to a novel coronavirus (later named SARS-CoV-2) started in Wuhan, China and rapidly spread in China and outside The WHO declared the epidemic of COVID-19 as a pandemic on March 12th 2020 . According to a recent Chinese study, about 80% of patients present with mild disease and the overall case-fatality rate is about 2.3% but reaches 8.0% …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 1, 2023 · pp. 29–35 Read article
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Edible Transgenic Plant Vaccines – An Overview and Update
Abstract: Normal 0 false false false EN-IN X-NONE X-NONE Plants are used as bioreactors to express antigenic molecules to be administered as vaccines. Edible transgenic plant vaccines (ETPV) are plant materials (recombinant protein subunit vaccines), and the edible plant tissue functions as an oral vaccine. ETPV are mucosal targeted vaccines where stimulation of both systematic and mucosal immune network takes place and these diminish the utilization of conventional animal or bacterial …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 2, 2011 · pp. 6–19 Read article
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Host Interface of Cystic Fibrosis and P. aeruginosa
Abstract: A clash between microbial infection and host immunity can contribute to multiple diseases. Cystic fibrosis is one of those diseases. It’s an autoimmune disorder and hyperinflammatory disease, caused by pseudomonas aeruginosa, it’s the most predominant pathogen causing this disease. The progression of the lung infection cystic fibrosis is driven by host pathogen interface that focuses on the host and the bacterial factors. The disease has an interplay between the host, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 9–31 Read article
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Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article