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705 articles for “Acidic pH”
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In Silico Screening of Terminalia chebula Phytocompounds as Potential Inhibitors of NTCP and DDB1 in Hepatitis B Virus Infection
Abstract: Hepatitis B virus (HBV) infection is a major global health concern, and chronic carriers are at risk of developing cirrhosis, hepatocellular carcinoma (HCC), and even death. Existing treatments can effectively inhibit viral replication, but they achieve little eradication of the virus because of covalently closed circular DNA (cccDNA) retention. In this investigation, bioactive compounds of Terminalia chebula, a plant known for its hepatoprotective and antiviral properties in traditional medicine, were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 33–44 Read article
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Impact of Amiloride-Hydrochlorthiazide Diuretic Against the Pathway of Uric Acid – VLDL and Peroxynitrite in Essential Hypertension
Abstract: Thiazides induce metabolic derangement in terms of hyperlipidemia, glucose intolerance, hyperuricemia and electrolytes imbalance. Co-amiloride-hydrochlorthiazide therapy favorably corrects the hypokalemia that is induced by thiazides alone. This study was aimed to identify the interactions between serum uric acid, very-low-density-lipoprotein (VLDL) and peroxynitrite in essential hypertensive patients using amiloride-hydrochlorthiazide as antihypertensive therapy. A total number of fifty patients (12 males and 38 females) with a history of hypertension were admitted in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 6–11 Read article
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Pharmaco-Nutraceutical and Chromatographic Study of Wattakaka Volubilis (Linn. f.) Stapf. Leaves
Abstract: Wattakaka volubilis (Linn.f.) stapf. (Asclepediaceae), twinning shrub, is used as a source plant of Jeevanti, an established drug of Ayurveda. Its leaves are used by the tribal people as a source of vegetable. The present work has been undertaken, to establish the necessary pharmacognostical, nutraceutical, physicochemical and HPTLC characters of leaves of Wattakaka volubilis following standard procedures. Results showed that the leaves are simple, petiolated, opposite, cordate to ovate, hispidly …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 1, Issue 2, 2014 · pp. 23–28 Read article
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A Study on Ethnomedicinal Properties of Tinospora cordifolia in Ranchi District of Jharkhand, India
Abstract: Guduchi (Tinospora cordifolia) is commonly called as Rasayana plant and its rejuvenating property is well described in the Ayurveda and other ancient literature. Surveys were carried out during January 2017 to March 2018 in different regions of Ranchi district of Jharkhand, India in order to collect the ethnomedical data. The survey provides evidence that the local people, tribal healers and folks are continuing to use this plant for various medicinal …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 19–22 Read article
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HPTLC Fingerprinting of Isoflavonoids and Metabolites Quantification from in vivo and in vitro Developed Parts of Pueraria tuberosa (Willd.) DC
Abstract: Pueraria tuberosa (Willd.) DC, a medicinally important plant, produces different types of isoflavonoids including Genestein. This plant requires conservation. In present study, callus was developed from in vivo tuber and in vitro seedling. Murashige and Skoog medium supplement with combination of BAP (6-Benzylaminopurine) (1.5mg/l) and 2,4-D (1.5mg/l) were found to be more effective. Fresh in vitro shoots produced from nodal explants of in vitro germinated seedling on MS medium supplement …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 3, 2019 · pp. 34–45 Read article
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Suitability Analysis of Different Batteries with Off-Grid Photovoltaic System
Abstract: The main objective of power generation and distribution companies is to ensure uninterrupted supply at reasonably low cost, minimum losses and high quality. Considering rural areas, where off-grid power systems using renewable resources are becoming more popular are generally equipped with storage elements like batteries. Hence energy storage and battery management system are a vital area of research nowadays. The study presents modelling of an off-grid solar PV model and …
Published in Research & Reviews : Journal of Physics · Vol. 7, Issue 3, 2018 · pp. 11–19 Read article
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Polyphasic Characterization and Comparative Genomics of a Newly Isolated Strain of Kocuria soli from Wild Ass Sanctuary, Gujarat, India
Abstract: From soil sample collected from Little Rann of Kutch-Wild Ass Wild Life Sanctuary, Gujarat a bacterial strain that is non-motile, cocci in shape, obligate aerobic, gram positive, catalase and oxidase positive was isolated and named as strain JC486. Strain JC486T was related to Kocuria soli M5W7-7T (99.7%) belonging to genus Kocuria according to sequence similarity and comparison data of 16S rRNA gene. The strain JC486T had a G+C content (DNA) …
Published in Journal of Water Pollution & Purification Research · Vol. 9, Issue 3, 2022 · pp. 16–22 Read article
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Molecular Docking Analysis of Punica granatum Compounds as Potential Inhibitors for Colorectal Cancer-Associated Molecular Targets
Abstract: Objective: Cancer is one of the most common worldwide disease which threat the life of a person. Colorectal cancer is one of the common cause of death nowadays. As computation approach is now employed for new drug discovery, target protiens like CDK-2, matrix metalloproteinase 2 (MMP-2), cyclin A, poly (ADP- ribose) polymerase (PARP-1) and Cox2 were chosen to perform molecular docking against the derivatives of Punica granatum phtyochemicals and Food …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 03, 2022 · pp. 28–42 Read article
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Evaluation of Physiochemical, Functional and Sensory Properties of Ice-Cream Incorporated with Tomato Juice
Abstract: AbstractRecently, consumers have tended to functional foods with more natural antioxidants, dietary fibers, minerals, vitamins, natural colorants and free of synthetic additives, etc. and tomato juice ice-cream will greatly contribute to this feature. This study determines the effect of tomato juice concentrations on the physico-chemical, functional and sensory properties of tomato juice ice cream. pH, texture, viscosity, melting rate and overrun were used to analyze the physico-chemical and functional properties …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 9, Issue 1, 2020 · pp. 1–9 Read article
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Evaluation of Polymer-Ceramic Scaffolds for Dental Bone Regeneration
Abstract: Looking at the aspects of periodontal disease, traumatic injury, congenital defects, and the preparation of implant sites, the deficiency of dental bone, and its reconstruction, which has been simplified by many by oral and maxillofacial surgery, has proven to be a very hard and tedious task. There are many solutions which are clinically accepted, as the use of auto, allo, and xenografts, very common practices in surgery, but they come …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Paeonia emodi: An Ethnopharmacological and Phytochemical Review
Abstract: This review is an attempt to evaluate the phytochemical potential of the Paeonia emodi and covers the pharmacological and ethnopharmacological activities of its chemical constituents, newly isolated chemical compounds and their medicinal importance. P. emodi is used in several traditional medicinal systems in China, Korea, Pakistan, India and Thailand. Different isolated natural products like anthraquinones, terpenoids, tannins, carbohydrates, phenolics and tannins, glycosides, paeoniflorin, lactiflorin, oxypaeoniflorin, cycloartenol, cholesterol, sitosterol, campesterol, emodinol, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 6, Issue 2, 2017 · pp. 11–20 Read article
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The Multifaceted Vitamin B6: Metabolism, Cardiovascular Health, Cognition, and Cancer
Abstract: Vitamin B6 is hydrophilic and plays a crucial role in various metabolic processes. It acts as a cofactor in different enzymatic reactions. Vitamin B6 exists in various forms, including pyridoxal 5'-phosphate (PLP), the most active form. Vitamin B6 is essential for amino acid metabolism, such as PLP is essential for transamination, the process of transferring amino groups between amino acids. This is vital for synthesizing non-essential amino acids and breaking …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 33–39 Read article
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Unlocking Novel Drug Targets and Therapeutic Advancements Against RNA Viruses: Insights from HMPV and SARS-CoV-2
Abstract: Re-emerging RNA viruses pose a significant epidemiological welfare threat due to their high mutation rates, potential for zoonotic transmission, and capacity to cause widespread outbreaks such as Human Metapneumovirus (HMPV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, etc. The rapid evolution and re-emergence of these viruses necessitate the development of novel drug targets and therapeutic strategies to combat existing and future outbreaks. This study focuses on structural as well …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 54–86 Read article
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Investigation on The Effect of Carbon Fiber Reinforcement on The Mechanical and Physical Properties of FDM 3d Printed PLA
Abstract: In this work, the effects of annealing on the physical properties and mechanical behavior of short-carbon-fiber-reinforced polylactic acid (CF/PLA) composites made using fused deposition modeling (FDM) are systematically investigated. Pristine PLA and CF/PLA composites with 10% fibers have been made and evaluated in accordance with ASTM standards. Tensile, bending, and hardness tests were used to evaluate the performance of as-received and annealed composites. The tensile and hardness properties of PLA …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 284–298 Read article
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Biopolymer Degradation and Structure–Property Relationships in Ageing: A Polymer Science Perspective
Abstract: Ageing, as viewed from the polymer sciences perspective, is perceived as the gradual modification of the structure-property-function interrelationship of biopolymers such as proteins, polysaccharides, nucleic acids and their molecular aggregates. Such changes include structural organization, mechanical behavior, physicochemical stability and functional effectiveness. Ageing is an inevitable multifactorial polymeric process. Due to the growing aging population globally, more age-associated complications emerge, which are correlated with the molecular degeneration of biopolymeric complexes. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 479–489 Read article
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Ragi: A Powerhouse of Nutrients
Abstract: Finger millet (Ragi, Eleusine coracana), is the principal food grain of the rural population in India, especially in South India. It is very nutritious with respect to minerals, dietary fiber and essential amino acids. Amongst cereals, Ragi provides highest level of calcium including antioxidants and phytochemicals. The total dietary fiber of finger millet grain is relatively higher than that of most of other cereal grains, which helps to control blood …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 3, 2016 · pp. 36–47 Read article
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Utilization of Moringa Pod Powder as a Value Added Ingredient in Lassi
Abstract: The present study was conducted to formulate a recipe and develop a method for manufacture of Moringa lassi containing Moringa pod powder (MPP) as a value added ingredient. Moringa lassi was prepared from dahi made from standardized milk (4.5% fat/9.5% MSNF). The effect of varying level of total milk solids in lassi (6 to 10% w/w of lassi), acidity of dahi (0.6 to 0.9% LA) and level of MPP (1.25 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 7, Issue 1, 2018 · pp. 6–17 Read article
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Therapeutic Potential of Plant-Derived Phytochemicals in Targeting Receptor Pathways Related to Non-Enzymatic Glycation: A Meta-Analysis
Abstract: Background: Non-enzymatic glycation, where reducing sugars react with proteins, lipids, and nucleic acids, contributes to various pathological conditions, such as diabetic complications and cardiovascular diseases. This process is facilitated by the receptor for advanced glycation end-products (RAGE), which is pivotal in driving inflammation and causing tissue damage. Objective: This meta-analysis evaluates the effects of plant-derived phytochemicals on RAGE expression and associated signaling pathways, assessing their therapeutic potential in glycation-related diseases. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 60–73 Read article
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A Comparative Study of Neem Oil and Mahogany Oil as Corrosion Inhibitors for Mild Steel Exposed to Hydrochloric Acid
Abstract: Corrosion is essentially an oxidation process, wherein the oxidizing agent itself undergoes reduction due to the influence of corrosion agents like salt, air, or moisture. Metals and their alloys naturally tend to react spontaneously with their surroundings, leading to a detrimental impact on their mechanical and physical properties. This project aimed to evaluate the effectiveness of two different oils, namely neem oil and mahogany oil, as agents to prevent acid …
Published in Recent Trends in Fluid Mechanics · Vol. 10, Issue 2, 2023 · pp. 13–18 Read article