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360 articles for “prediction tool”
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Role of Artificial Intelligence in Simulation and Therapeutics in Neurodegenerative Diseases
Abstract: Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc., are a cause of significant mortality rates due to a lack of curative treatments and their complex nature. Traditional therapeutic methodologies have several disadvantages such as slow diagnosis and a lack of effective treatments. They mainly focused on the management of the disease rather than curing it. The integration of artificial intelligence in the simulation and therapeutics of neurodegenerative …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 19–29 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Inclusion Removal Study in a Integrated Tundish-Nozzle-Mold System by CFD
Abstract: CFD modelling is a powerful tool to study the complex flow phenomena happening in each step of the continuous casting process; considering this, the current research shows the impact of tundish turbulent phenomena on fluid dynamics and steel cleanliness considering an integrated system: tundish, nozzle, and mold. The mathematical simulations consider 3D cartesian coordinates for the continuity and Navier-Stokes equations together with the turbulent realizable and the multiphase VOF models. …
Published in Recent Trends in Fluid Mechanics · Vol. 9, Issue 2, 2022 · pp. 1–14 Read article
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Flood Frequency Analysis of Big Akaki River, Awash Basin, Ethiopia
Abstract: Flood is one of the most dangerous naturally occurring catastrophic hazards now days displacing and killing people and destroying properties. During high flow, the Big Akaki River flooded the vicinity of the area and causes loss of cultivated land and life. Flood water inundates the floodplain areas and cause vast damages to life and property. The main objective of this paper is to analyze the inundation area along the Big …
Published in Journal of Water Resource Engineering and Management · Vol. 8, Issue 2, 2021 · pp. 35–48 Read article
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From Differential Equations to Data Science: A Survey on Analytical Methods in Contemporary Problems
Abstract: The integration of differential equations and data science methods represents a dynamic and evolving approach to solving contemporary challenges across a wide range of disciplines, including engineering, physics, biology, economics, and finance. Differential equations have long served as fundamental tools for modeling continuous systems and processes, offering powerful insights into the behavior of natural and man-made phenomena. For example, they describe how heat diffuses through materials, how populations grow in …
Published in Recent Trends in Mathematics · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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AI Adoption in Medical Libraries: A Study on SDMH’s Use of Ovid Discovery AI and Its Impact on Evidence-Based Medicine
Abstract: The role of Artificial Intelligence (AI) in transforming medical libraries is increasingly significant as these libraries evolve to become intelligent, responsive hubs for knowledge dissemination. This paper explores the adoption of AI tools at Santokba Durlabhji Memorial Hospital (SDMH) Medical Library, focusing on the integration of Ovid Discovery AI, a cutting-edge tool designed to enhance literature search accuracy, summarize content, and provide context-aware recommendations. Using a mixed-methods approach, the study …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 2, 2026 · pp. 1–9 Read article
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Big Data, Big Impact: The Role of Analytics in Modern Business
Abstract: In modern business, “Big Data” signifies the vast amount of data collected from various sources, and “Big Data Analytics” refers to the process of analyzing this data to extract valuable insights, enabling companies to make data-driven decisions, optimize operations, better understand customers, and ultimately gain a competitive edge by identifying trends, patterns, and opportunities that might otherwise be missed. This study analyzes large datasets, by which businesses can gain deeper …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 2, 2025 · pp. 01–11 Read article
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Multi-Scale Analysis of Polymer Based Energy Storage Systems for High Performance Battery Applications
Abstract: The energy storage systems based on polymers are becoming promising materials for the next generation of high performance batteries because of their excellent mechanical flexibility, improved safety, and favorable electrochemical properties. Even with computational tools in Python, polymer-based energy storage systems remain plagued by poor ionic conductivity, complicated electrochemical reactions and potential thermal runaway. Therefore, a multi-scale model is proposed to improve battery performance, thermal stability, reliability, and large-scale deployment …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1035–1048 Read article
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Empirical Relation to Predict Essential Oil Yield in Conventional Distillation System
Abstract: Peppermint is medicinal herb, and its extracts (essential oils) are of great importance because they are used in pharmaceutical, food, and cosmetic items. Moreover, peppermint oil is also used as anticancer, anti-bacterial, anti-viral, spasmodic, anti-diabetic, ulcer healing, anti-obesity, etc. Steam distillation method is used to extract essential oil from peppermint. Boiler, extraction unit, condenser and Florentine flask are the main components of steam distillation system. The objective of present study …
Published in Journal of Polymer & Composites Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Application of GIS tools to the Improvement of Energy Supply in PV Rooftop Installations
Abstract: Present work studies the energy supply from photovoltaic (PV) installations in industrial conglomerates using the rooftops as a surface to install the PV panels. The study is based on a modelling procedure that takes into account the specific characteristics of the rooftop, shape, size, azimuth and inclination, using GIS tools to identify these parameters for every single rooftop. Modelling has been developed modifying the tilt angle of the PV panel …
Published in Journal of Remote Sensing & GIS Read article
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Remote Sensing in Atmospheric Studies: Enhancing Understanding of Climate Dynamics and Air Quality, Atmospheric Monitoring and Analysis; Emerging Technologies and Future Directions
Abstract: Remote sensing has emerged as a transformative tool in atmospheric sciences, providing detailed and comprehensive insights into various atmospheric phenomena. Its advanced capabilities have revolutionized our understanding of climate dynamics, air quality, and atmospheric composition, enabling more accurate monitoring and analysis. This paper reviews the critical role of remote sensing technologies in enhancing knowledge of atmospheric processes and their practical applications in areas such as climate change monitoring, air pollution …
Published in International Journal of Atmosphere · Vol. 2, Issue 1, 2025 · pp. 1–5 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Optimization of Turning Parameters of EN-36 for Material Removal Rate and Tool Life based on Taguchi and RSM Method
Abstract: In this experimental study the effect of cutting parameters on material removal rate (MRR) and tool wear rate (TWR) during turning of EN-36 material on turning machine is determined. In this work, firstly, all the cutting parameters namely, spindle speed (SS), feed rate (FR) and depth of cut (DOC) are designed by using suitable orthogonal array in Taguchi method. The experimental studies were accompanied under the varying spindle speed, feed …
Published in Journal of Mechatronics and Automation · Vol. 3, Issue 1, 2016 · pp. 14–24 Read article
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Comparative Evaluation of GPBB and CK-MB in Early Diagnosis of Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients
Abstract: Background: Acute myocardial infarction (AMI) continues to be a leading cause of morbidity and death among people worldwide. To lower the risk of problems, early and precise diagnosis is essential, particularly for diabetes patients. The study investigates the diagnostic value of Glycogen Phosphorylase BB (GPBB), a potential early biomarker of myocardial necrosis, and compares it with CK-MB, a widely used cardiac marker, in AMI diagnosis. Inflammatory markers (hs-CRP, IL-6, TNF-α) …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 33–37 Read article
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Quantification of Snow/Glacier Melt Impacts of Historical and Future Climate Change on Eastern Himalayan River
Abstract: Millions of the population on Eastern Himalayan Rivers (EHR) totally depend on, domestic use, agriculture, and hydropower. Several studies found that climate warming threatens this EHR's hydrological regime. In order to understand the hydrologic response of their headwaters and how climate change affects streamflow, a hydrological modeling study is conducted in the Teesta River Basin (TRB) in EHR using an open-source Quantum Geographical Information System (QGIS) with semi-distributed QSWAT1.5 (Soil …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 508–524 Read article
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Gene Edited Livestock for Enhanced Feed Efficiency and Metabolic Adaptation Through Precision Genomic Interventions
Abstract: Advances in gene editing technologies have transformed the landscape of livestock production by enabling precise manipulation of genetic material associated with productivity, health, and environmental adaptability. Tools such as CRISPR Cas9 and emerging next generation editors allow targeted modifications that improve feed efficiency, growth performance, nutrient utilization, and stress tolerance in farm animals. This review highlights the genetic basis of feed efficiency and metabolic regulation, focusing on key genes and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
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Accelerate Drug Development with Pharmacokinetic Softwares
Abstract: During continuously evolving technologies and mechanized equipments, there has been a tremendous growth in the pharmaceutical sector over the past few decades. New technologies, software, devices, and techniques are being developed or researched upon with each passing day. By leveraging pharmacokinetic software, researchers can efficiently analyze vast datasets from preclinical and clinical studies, extracting actionable insights that inform decision-making early in the development cycle. This predictive capability not only accelerates …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Mathematical Modelling of Semiconductor Device Physics: An Analytical Approach
Abstract: Semiconductor device physics forms the foundation of modern electronic and optoelectronic technologies. Mathematical modelling provides a rigorous framework for understanding, predicting, and optimizing the behavior of semiconductor devices by linking physical principles with device-level performance. This work presents an analytical approach to the mathematical modelling of semiconductor devices, emphasizing the derivation and interpretation of governing equations that describe charge transport and electrostatic behavior. The model is based on fundamental physical …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 1, 2026 · pp. 36–42 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article