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475 articles for “Pathways”
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AI-Driven Prediction of Square-Hole Laser Trepanning Performance in AA7075/15%SiC/15% Glass Fiber Hybrid Composites Using Taguchi–ANOVA and Deep Neural Networks
Abstract: Hybrid AA7075 composites reinforced with 15% silicon carbide (SiC) and 15% glass fiber were fabricated via the stir casting technique to improve machining and structural performance. The addition of dual reinforcements into the aluminum matrix was aimed at enhancing hardness, thermal stability, and surface quality during non-traditional drilling operations. Square-hole drilling was performed using a laser trepanning process, and the key responses—hole size accuracy, surface roughness, and taper angle—were systematically …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1932–1943 Read article
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Renewable-Powered HVAC Systems: Advances in Solar, Bioenergy, and Heat Pump Technologies
Abstract: The global demand for refrigeration, air conditioning, heating, and ventilation (HVAC) systems has increased rapidly due to population growth, urbanization, industrialization, and rising expectations for indoor thermal comfort. These systems account for a substantial share of global energy consumption and greenhouse gas emissions, primarily because they rely heavily on fossil-fuel-based electricity and thermal energy. Consequently, the decarbonization of HVAC and refrigeration sectors has become a critical component of global climate …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 13, Issue 1, 2026 · pp. 26–33 Read article
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Comparative Study of Structural and Optical Properties of Bismuth Ferrite Nanoparticles for Photovoltaic Applications Synthesized via Different Sol-Gel Methods
Abstract: Pure multiferroic bismuth ferrite (BiFeO3) nanoparticles were successfully synthesized using an energy-efficient, low-temperature sol-gel method, comparing two distinct approaches: auto-combustion and non-auto-combustion. To ensure phase stability, the precursor solution's pH was strictly maintained between 1 and 2 using ammonia solution (NH4OH), while ethylene glycol (C2H6O2) was employed as a chelating agent for the Fe3+ and Bi3+ cations. All samples underwent a final annealing process at 500 °C to promote crystallization. …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 83–94 Read article
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Nutrient–Xenobiotic Crosstalk in Dairy Cattle: Implications for Metabolism, Immunity, Health, and Productivity in Resilient Dairy Development
Abstract: Dairy cattle are routinely exposed to a wide range of xenobiotics, including mycotoxins, heavy metals, pesticides, residues from veterinary drugs, and plant secondary metabolites, through feed, water, and environmental sources. These xenobiotics, being foreign to biological systems, can interfere with the absorption, metabolism, and utilization of essential nutrients, while also compromising immune function, organ health, and overall physiological performance. Chronic or subclinical exposure can reduce feed efficiency, disrupt energy and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 37–46 Read article
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Thermo–Electrical Performance Enhancement of a Lightweight Polymer–Metal Hybrid Electrostatic Precipitator Using Epoxy-Based Composite Housing for Industrial Particulate Control
Abstract: Airborne particulate emissions, particularly PM₁₀ and PM₂.₅ produced by industrial activities and combustion processes, they continue to pose a significant threat to both the environment and public health. Electrostatic precipitators (ESPs) are widely recognized for their ability to achieve high collection efficiencies; however, conventional metallic constructions often lead to increased system weight, higher fabrication costs, and long-term corrosion-related challenges. In this study, a lightweight hybrid material approach is proposed by …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 652–668 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 70–83 Read article
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Looking into new ideas in green chemistry
Abstract: Green chemistry has become a revolutionary way to change chemical processes such that they have less of an effect on the environment while still being efficient and cost-effective. This article looks at new developments in green chemistry that go beyond small changes and offer completely new ways to build chemicals that are good for the environment. There is a lot of focus on innovative catalytic systems, sustainable feedstocks, reaction pathways …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 10–18 Read article
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Effect of Microbial Species and Inoculum Dosage on Anaerobic Digestion
Abstract: This work aims at studying the effect of microbial species and inoculum dosage on anaerobic digestion of food waste using cattle rumen content as inoculum. Four different batch runs were carried out with different percentage inoculations which were (control sample), 25% dosage, 50% dosage and 75% dosage. To have both logical and scientific explanation why the inoculated samples had better performance than the control sample, microbial identification was carried out …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 1, 2026 · pp. 12–23 Read article
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Thin Film Technology in Sensor Manufacturing – A Technical Discussion
Abstract: Thin‑film technology has become the cornerstone of modern sensor manufacturing, enabling the convergence of miniaturisation, multifunctionality, and cost‑effective mass production. This paper surveys the latest advances in deposition techniques—ranging from magnetron sputtering and chemical vapour deposition to atomic‑layer deposition (ALD) and ink‑jet‑printed sol‑gel processes—and examines how their unique material‑control capabilities translate into performance gains across the sensor spectrum (chemical, physical, and bio‑sensing). By integrating nanoscale thickness control (≤ 10 nm) …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 13, Issue 1, 2026 · pp. 47–57 Read article
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A Knowledge Graph Approach for Breast Cancer Diagnosis and Data Sharing Platform Implementation in the Context of Human Papillomavirus Infection
Abstract: Background: Breast cancer remains among the most prevalent malignancies in women worldwide, and effective diagnosis and data integration continue to challenge clinical practice. Diagnostic reports from mammography and ultrasound contain rich clinical information that is often under-utilised due to heterogeneous formats and limited data-sharing infrastructure. In the context of human papillomavirus (HPV) infection, which may influence oncogenic pathways and data complexity, advanced computational methods offer new solutions to this problem. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article
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Correlation of Serum Vitamin D Levels with Insulin Resistance in Young Adults
Abstract: Among young adults, both insulin resistance (IR)and vitamin D deficiency are common and pose the risk of complications, such as type 2 diabetes mellitus (T2DM). A few studies demonstrated that vitamin D deficiency might negatively influence insulin sensitivity, but the results of these studies have been inconsistent and/or inconclusive. This review focuses on young adults and aims to summarize and critique studies that assess the relationship between IR and serum …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 69–74 Read article
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A study on Bridging Chemical Transformation and Climate Feedbacks in the Earth System
Abstract: The atmosphere operates as a vast and complex chemical reactor, where minute-scale transformations exert profound influence on planetary-scale climate stability. This research investigates the multi-scale coupling between reactive tropospheric chemistry and large-scale climate feedbacks, challenging traditional modeling approaches that often divorce chemical kinetics from dynamic processes. By integrating high-resolution chemical transport models (CTMs) with comprehensive Earth System Models (ESMs), we map the flow of energy and matter from the molecular …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 · pp. 34–46 Read article
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Machine Learning Optimization for VARTM Carbon Polymer Laminates
Abstract: Vacuum-assisted resin transfer moulding (VARTM) is a key low-cost, out-of-autoclave process for manufacturing large-scale carbon-fibre reinforced polymer (CFRP) laminates crucial to aerospace wings, wind-turbine blades, marine hulls, and automotive structures. Unpredictable resin flow often leads to voids, dry spots, and race-tracking defects, resulting in 27.9% scrap rates and lengthy, costly trial-and-error design cycles. Although surrogate models provide rapid impregnation predictions for simple flat-plate geometries, vision-based monitoring is limited to idealized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 229–245 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Thermo-Hydraulic Enhancement of Annular Finned Shell-and-Tube Heat Exchangers Using Epoxy-Based Polymer Composites: A Material–Geometry Coupled CFD Investigation
Abstract: Shell-and-tube heat exchangers remain a backbone of industrial thermal systems, yet their performance is often limited by relatively low shell-side heat transfer and the weight and cost associated with conventional metallic components. In this context, the integration of polymer composite materials offers a promising pathway toward lightweight, corrosion-resistant, and performance-tunable heat exchanger designs. The present study investigates the thermo-hydraulic performance of a straight-tube shell-and-tube heat exchanger equipped with annular fins, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 669–684 Read article
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Image-Based Evaluation of Implant Tissue Interface Integrity in Polymer Orthopaedic Devices
Abstract: Polymer orthopedic implants offer radiolucency and mechanical compatibility with bone, but long-term success depends on maintaining a stable implant–tissue interface. Routine imaging is widely available for follow-up, yet interface integrity is commonly judged qualitatively, limiting early detection of fixation compromise and reducing comparability across devices and time points. This work presents an image-based methodology to quantify interface integrity by extracting interpretable interface descriptors from a standardized interface belt around the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 170–179 Read article
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AI-Integrated Graphene-Modified Polymer Interfaces for Real-Time Crack Detection and Autonomous Healing in Smart Concrete Structures
Abstract: This study presents the design and development of a graphene-reinforced multifunctional polymer composite interface engineered for structural reinforcement, self-sensing, and autonomous healing applications in cementitious systems. A thermosetting polymer matrix embedded with graphene nanoplatelets (0.25–1.5 wt.%) was developed to establish a conductive polymer nano-composite network. Electrical characterization confirmed a distinct percolation threshold at ~0.6–0.8 wt.%, beyond which a sharp increase in conductivity was observed due to the formation of interconnected …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 30–42 Read article