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825 articles for “tar”
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Human Following Robot Using Arduino Uno
Abstract: A human-following robot is a mobile autonomous system designed to detect, track, and follow a specific individual in real-time while navigating through dynamic environments. This feature is essential for various applications, including delivery services, healthcare assistance, personal support, and collaborative industrial operations. It enhances efficiency, safety, and user experience by enabling intelligent and responsive interactions, making it an asset in both commercial and personal environments. The robot integrates cameras, LiDAR, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 3, 2025 · pp. 26–31 Read article
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Revolutionizing Vaccine Development:The Transformative Role of Bioinformatics in Designing Next-Generation Immunotherapies
Abstract: Vaccines have long been central to the prevention and control of infectious diseases, dramatically reducing morbidity and mortality worldwide. In the modern era, the integration of bioinformatics has revolutionized vaccine development by enabling rapid, precise, and cost-effective identification of potential vaccine targets. This seminar explores the multifaceted applications of bioinformatics in vaccinology, including antigen discovery, epitope prediction, structural modeling, molecular docking, and immunoinformatics-driven vaccine design. Special emphasis is placed on …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 19–33 Read article
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A Comprehensive Review on Nanostructured Polymer Composites for CT Imaging Contrast Enhancement in Brain Tumor Diagnosis
Abstract: The detection and characterization of brain tumors require high-resolution and non-invasive imaging modalities that have the ability of differentiating tumorous tissues and healthy brain tissues. Computed tomography (CT) can be included in this number because, in addition to providing speedy scans and penetration to deep tissue, the diagnostic capability in soft tissue organ such as the brain is poor despite low natural contrast. The review is dedicated to the emerging …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 148–162 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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A Study on Recent Trends in Chemical Sensors for Detecting Toxic Materials
Abstract: Poisonous materials, such as mutagenic, carcinogenic, and poisonous compounds, are widely produced as a result of industrial development. Such materials continue to be hazardous to human health despite stringent management and control procedures. As a result, practical chemical sensors—such as optical, electrochemical, nanomaterial-based, and biological system-based sensors—are needed for the monitoring of dangerous chemicals. For the detection of harmful compounds, numerous new and existing chemical sensors are being created, along …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 26–35 Read article
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Effectiveness of Public Health Campaigns in Reducing Oral Cancer Incidence in Urban Maharashtra
Abstract: Introduction: Oral cancer is a major public health problem in urban Maharashtra which can be attributed to high consumption of tobacco, late presentation, and poor awareness. To tackle these issues, public health campaigns have been established to encourage early diagnosis, lifestyle modification, and availability of health resources. This study assesses the impact of these campaigns on the reduction of oral cancer incidence and awareness level in the population. Methods: This …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 1–8 Read article
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Breast Cancer Screening Awareness and Participation Among Women in North India
Abstract: Breast cancer is the most prevalent malignancy among Indian women, accounting for 25% of all female cancers (ICMR, 2020). Significant urban-rural disparities in screening persist across North India due to socioeconomic, cultural, and healthcare access barriers. This study evaluates these disparities to inform targeted interventions. A cross-sectional study was conducted among 1,500 women (750 urban, 750 rural) in Delhi, Uttar Pradesh, Punjab, and Haryana, using stratified random sampling. Data were …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 43–50 Read article
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Assessing the Increasing Incidence of Prostate Cancer in Urban Delhi: Risk Factors, Early Detection, and Treatment Challenges
Abstract: Background: Prostate cancer has emerged as the second most prevalent cancer among men in India, with rapidly increasing incidence rates in urban areas like Delhi. This rise is attributed to urbanization, lifestyle changes (high-fat diets, tobacco use, sedentary behavior), increased life expectancy, and improved diagnostics. Despite its growing burden, low awareness, limited screening programs, and treatment barriers hinder early detection and effective management. This study examines the epidemiological trends, risk …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 21–28 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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Cancer Chemotherapy-Induced Cachexia: Bridging Mechanisms, Management, and Future Therapies
Abstract: Involuntary weight loss, skeletal muscle atrophy, adipose tissue depletion, anorexia, and systemic inflammation are all symptoms of chemotherapy-induced cachexia, a complex illness. Although it is common, it remains poorly understood and is often referred to as an "orphan disease." This study covers the epidemiology, pathophysiology, clinical symptoms, diagnosis, treatment, and emerging treatment options for chemotherapy-induced cachexia. To comprehend the causes, clinical results, and therapeutic approaches, a literature-based synthesis of recent …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 17–26 Read article
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A Shear Strength Reduction Method for an Open Pit Slope Stability Analysis Based on Finite Element Method
Abstract: Slope stability assessment of open pit mines is critically important, since it forms part of the overall productivity and safety management strategy of the mines. The aim of this work is to investigate the overall stability conditions of three (3) open pits in Gold Fields Limited, Tarkwa Ghana. Field and laboratory investigations were conducted as well as empirical methods. Finite Element Analysis (FEA) in Rocscience was carried out using the …
Published in Journal of Geotechnical Engineering · Vol. 13, Issue 1, 2026 · pp. 1–24 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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LPG GAS Weight Measuring Stand.
Abstract: The LPG Gas Weight Measurement Stand is a novel project, with the target to measure the leftover weight of Liquefied Petroleum Gas (LPG) in cylinders precisely so that it can be consumed efficiently and also refilled punctually. Traditional methods depend upon manual guess or weighing scales, which are tiresome and inaccurate. The project presents a dedicated weighing stand with a load cell sensor, microcontroller (such as Arduino or ESP8266), and …
Published in Recent Trends in Sensor Research & Technology · Vol. 13, Issue 1, 2026 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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Nanoparticle and Lipid-Based Vaccine Delivery Systems: A Systematic Review of Platforms, Stability, Pharmacokinetics, and Immune Modulation
Abstract: The rapid evolution of vaccine technologies over the past decade has highlighted the transformative role of nanoparticle (NP) and lipid-based delivery systems in modern immunization practices. These platforms – including polymeric nanoparticles, lipid nanoparticles (LNPs), liposomes, nanoemulsions, and solid lipid nanoparticles (SLNs) – enable enhanced antigen stability, improved cellular uptake, targeted antigen delivery, and potent immune activation. This systematic review critically examines the physicochemical foundations, manufacturing approaches, stability challenges, pharmacokinetic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 18–36 Read article
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Modern Approaches in Lung Cancer Management from Herbal Nanomedicine to Artificial Intelligence
Abstract: Lung cancer continues to be a major global health concern and one of the leading causes of cancer-related mortality worldwide. Despite significant advancements in therapy, there is still a pressing need for safer and more effective therapeutic alternatives; problems such drug resistance, side effects, metastasis, and recurrence continue to impact patient outcomes and quality of life. Examining current advancements in the use of herbal drug-loaded nanoparticles as a novel approach …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article