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401 articles for “profiling”
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A Comparative Review on Abelmoschus palianus and Barleria mysorensis: Phytochemical Constituents, Pharmacological Potentials, and Ethnobotanical Significance
Abstract: Medicinal plants have long served as invaluable resources for treating human ailments, with countless species still awaiting scientific exploration and validation. Abelmoschus palianus and Barleria mysorensis are two such botanicals with rich ethnomedicinal heritage but limited pharmacological characterization. This review presents a detailed comparative analysis of these two species, examining their botanical descriptions, geographic distribution, traditional applications, phytochemical constituents, pharmacological properties, toxicological profiles, and therapeutic potential. Abelmoschus palianus, native to …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 7–13 Read article
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Phytoconstituents of Ticanto crista (L.) R. Clark & Gagnon (Caesalpiniaceae): A Review
Abstract: Ticanto crista (L.) R. Clark & Gagnon (= Caesalpinia crista L.), a member of the Leguminosae family, is a medicinally important plant traditionally used in various systems of medicine, including Ayurveda, for treating a wide range of ailments. It has attracted increasing scientific interest due to its rich phytochemical profile and therapeutic potential. This review serves as a comprehensive index of the chemical structures of common and medicinal compounds isolated …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 3, 2025 · pp. 38–59 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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Applications of Nanotechnology in Crop Improvement: New Era of Agriculture
Abstract: It represents a transformative force in agriculture, promising to improve the productivity, yield, sustainability, and food security. This review paper focused on the certain advantages of nanoscience and nanotechnology in enhancing the agricultural productivity, disease management, and food safety. By manipulating different materials and objects at the nanoscale, researchers can develop advanced tools such as smart sensors and targeted delivery systems that improve nutrient absorption and combat plant pathogens. By …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 46–54 Read article
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Termite Mound Soil: A Potential Source of Biofertilizer in Koraput, Odisha
Abstract: Mass use of chemical fertilizers and extensive agriculture has reduced soil’s physiochemical properties and nutrient profile, generating crops with higher chemical residues, resulting unhealthy human population. Sustainable and cost effective nature friendly alternative methods of agriculture are the present need, to overcome the crisis. The study with Termite Mound Soil, TMS, in Koraput district of Odisha, India was performed to find nutrient composition and its potential as an ecofriendly, sustainable …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 3, 2025 · pp. 40–47 Read article
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Gear-Related Stress Analysis and Comparison Between the Fem and Agma Standards
Abstract: In many different devices, gears enable the efficient transfer of motion and torque. They are an essential component of modern mechanical power transmission systems. It has been demonstrated that bending and surface contact stresses at the gear tooth are the primary causes of gear failure, despite their widespread use. Too much stress can lead to tooth wear, pitting, or breakage, which can ultimately reduce the operating life and reliability of …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 13–18 Read article
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Revolutionizing Vaccine Development:The Transformative Role of Bioinformatics in Designing Next-Generation Immunotherapies
Abstract: Vaccines have long been central to the prevention and control of infectious diseases, dramatically reducing morbidity and mortality worldwide. In the modern era, the integration of bioinformatics has revolutionized vaccine development by enabling rapid, precise, and cost-effective identification of potential vaccine targets. This seminar explores the multifaceted applications of bioinformatics in vaccinology, including antigen discovery, epitope prediction, structural modeling, molecular docking, and immunoinformatics-driven vaccine design. Special emphasis is placed on …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 19–33 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Design, Synthesis, and Evaluation of Novel Quinazoline Derivatives as Anti-Inflammatory Agents
Abstract: Novel quinazoline derivatives are well-known heterocyclic scaffolds that are renowned for having a wide range of biological functions. A new quinazoline derivative was synthesized from anthranilic acid through a multi-step sequence involving amide formation, cyclization, and aromatic group substitution. The structure of the methoxy- and chloro-substituted final compound was confirmed by IR and 1H NMR spectroscopy. Evaluation of synthesized molecules anti-inflammatory activity using paw edema caused by carrageenan paradigm in …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 01–09 Read article
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Impact of Specially Prepared Food on Indian Big Carp Growth in West Bengal, India’s Cooch Behar District
Abstract: This four-year longitudinal study (2008–2012) in the Cooch Behar District of West Bengal, India, utilized on-farm ponds to evaluate the comparative growth performance of Indian Major Carps (IMCs) – Catla catla, Labeo rohita, and Cirrhinus mrigala – when subjected to four distinct supplementary feed formulations: fishmeal (A), soybean meal (B), silkworm pupae (C), and mustard oilcake (D). The experimental design contrasted treated ponds receiving formulated feed against control ponds relying …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 7–12 Read article
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Approximation-Aware Computation for Graceful QoS Degradation in Modern Multiprocessor Operating Systems
Abstract: Modern multiprocessor operating systems face unprecedented challenges in maintaining Quality of Service (QoS) guarantees under dynamic workload conditions and resource constraints. Traditional approaches to resource management often result in abrupt service degradation or complete task failure when system resources become scarce. This study presents a comprehensive framework for approximation-aware computation that enables graceful QoS degradation in multiprocessor environments. We explore the integration of approximate computing paradigms with operating system schedulers, …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 3, 2025 · pp. 08–15 Read article
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A Review on Lung Cancer Prediction Using Machine Learning
Abstract: Lung cancer continues to be a major contributor to cancer-related mortality across the globe. Timely diagnosis and reliable prediction models play a crucial role in enhancing treatment outcomes and survival rates for patients. The present study focuses on the utilization of machine learning (ML) methods for the prediction of lung cancer. Using datasets that incorporate clinical records, imaging modalities, and genetic profiles, the research assesses the predictive capabilities of multiple …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 1–11 Read article
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Immune Dysregulation and Cytokine Circuitry in Genital Endometriosis: Mechanistic Insights and Next-Generation Immunotherapeutic Strategies
Abstract: Genital endometriosis is increasingly recognized as an immune-mediated inflammatory disorder driven by complex interactions between dysregulated immune cells, cytokine hubs, and microbiome-derived modulators. This review introduces a novel “immune–cytokine circuitry” framework that unifies innate and adaptive immune abnormalities with key cytokine loops sustaining chronic inflammation, angiogenesis, neuroinflammation, and immune tolerance. Within this circuitry, macrophage polarization, dendritic cell immaturity, NK-cell anergy, Treg expansion, Th17 amplification, and B-cell–mediated autoimmunity converge to establish …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 06–16 Read article
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Study on the Method of Constructing a System of Linear Equations for Calculating Aerodynamic Derivatives
Abstract: The aerodynamic derivatives can be calculated from the unsteady hydrodynamic forces experienced by the harmonic-oscillating vehicle. Until now, unsteady flow field analysis in aerodynamic derivative calculations has been applied mainly to thin bodies based on potential theory MSC. Nastran is a typical application based on potential theory MSC. Natran can calculate the aerodynamic derivatives of the vehicle relatively well in the subsonic region, but in the supersonic region, the fuselage …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 3, 2025 · pp. 14–24 Read article
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Coupled Magneto–Thermal–Diffusion Transport in an Unsteady Maxwell Polymer Fluid with Activation Energy over a Porous Stretching Surface
Abstract: The present study investigates the combined effects of activation energy and diffusion-thermo (Dufour) processes on unsteady magnetohydrodynamic (MHD) flow, heat, and mass transfer of a Maxwell viscoelastic fluid past a porous exponentially stretching vertical sheet. The electrically conducting and incompressible polymeric fluid flows through a saturated porous medium under a transverse magnetic field. The governing momentum, energy, and concentration equations are transformed into nonlinear ordinary differential equations using similarity transformations …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 581–590 Read article
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Comparative Thermal Stability of Structural Acrylic and Polyurethane Adhesives under High Heating Rate Conditions
Abstract: This study examines the thermal stability and degradation characteristics of structural acrylic and polyurethane adhesives through Differential Scanning Calorimetry (DSC) at an elevated heating rate of 15 °C/min. The purpose of this study is to assess the impact of rapid thermal excitation on the volatile loss of adhesives, their curing behaviour, and thermal decomposition profiles elements that are essential in high-speed manufacturing and thermally challenging settings. The findings indicated that …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 717–725 Read article
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Enhancing Worker Comfort in High-Heat Environments: A Triangular Bladeless Cooling Fan Approach
Abstract: Workers in high-heat industrial environments frequently encounter thermal stress, fatigue, and dehydration, which significantly impact both productivity and safety. Existing cooling solutions such as pedestal fans, ceiling fans, and central air-cooling systems often fall short due to limited airflow reach, safety concerns from exposed blades, high energy consumption, and poor suitability for dynamic workshop layouts. To address these challenges, this study presents a novel triangular bladeless fan designed specifically for …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 25–31 Read article
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Analysis of Simply Supported and Clamped-Clamped Beam Resting on a Pasternak Foundation Subjected to Moving Load with a Damping Term
Abstract: A comparative analysis of simply supported and clamped-clamped Bernoulli-Euler beams resting on a Pasternak foundation under the action of a concentrated moving load with a damping term, when the inertia effect of the moving load is considered in its analysis, was investigated in this study. The governing equation was solved by representing the Dirac delta function through a Fourier cosine series and applying a combination of analytical techniques, including the …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 3, 2025 · pp. 42–59 Read article