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392 articles for “cancer”
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Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Multi-Target Molecular Docking of Anantmul (Hemidesmus indicus) Compounds for Tay-Sachs Disease Treatment
Abstract: This research aimed to study the effects of the plant Anantmul (Hemidesmus indicus) in the treatment of Tay-Sachs disease using molecular docking studies. Tay-Sachs disease is a neurodegenerative autosomal recessive disorder caused due to accumulation of the molecule GM2 ganglioside which is caused due to lack of enzyme Beta Hexosaminidase which breaks down GM2 Ganglioside. Anantmul (Hemidesmus indicus) is a an ayurvedic plant used in the Indian subcontinent that has …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 61–69 Read article
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A Review Article on Nutraceuticals – An Impact on Conventional Health Care
Abstract: Nutraceuticals, combining nutrition and pharmaceuticals, have transformed healthcare. This review explores their classification, scope, benefits, and challenges. Nutraceuticals, including dietary supplements, functional foods, herbal products, and fortified foods, promote health and prevent diseases. The global market, valued at $117 billion, is expanding rapidly, fueled by the growing focus on health. Key benefits are boosted health benefits, fewer side effects, natural options improved nutrition. Classification is traditional (conventional) nutraceuticals (e.g., lycopene, …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 9–23 Read article
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A Comprehensive Review of Antioxidant Activity of Bhringraj (Eclipta alba) : An Indian Ancient Herb
Abstract: Eclipta alba, commonly known as Bhringraj, is an herb widely utilized in traditional Indian medicine (Ayurveda) for its diverse therapeutic properties, particularly in promoting hair growth, enhancing liver function, and improving overall health. Among its numerous biological activities, the plant’s antioxidant potential has garnered significant interest in modern phytochemistry. Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and the body’s antioxidant defenses, is a key contributor to …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 12–21 Read article
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A Comprehensive Study of Nutrients Food in Nutraceuticals: Plant Extracts, Vitamins, Minerals, and Phytochemicals
Abstract: Nutraceuticals are biologically active substances obtained from food sources that offer health benefits beyond their basic nutritional value. They include plant extracts, vitamins, minerals, and phytochemicals, each of which plays a key role in supporting health, preventing disease, and optimizing physiological functions. This review examines the role of these nutrients in nutraceutical products, with a particular focus on their mechanisms of action, therapeutic effects, and potential clinical applications. Plant extracts, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 14–22 Read article
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Evaluating the Role of Alternative Medicines – A Critical Review of Therapies and Research
Abstract: Alternative medicine encompasses healthcare practices outside conventional medicine, including acupuncture, homeopathy, naturopathy, herbal medicine, yoga, and more. Despite growing popularity, alternative therapies often lack rigorous proof of effectiveness and long-term safety. This review examines various branches of alternative medicine, their benefits, and challenges. The paper discusses Ayurveda, homeopathy, acupuncture, naturopathy, herbal medicines, mind-body therapies, and manipulative and body-based therapies. It highlights the pros and cons of alternative medicine, including holistic …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 1–15 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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A Review study of Mn-Zn Ferrite with Applications and Synthesis processes
Abstract: The distinct magnetic characteristics and adaptability of Mn-Zn ferrites make them broadly applicable in a wide range of industries and applications. Temperature stability, high electricity resistivity, magnetic permeability, permittivity, saturation magnetization, and low power losses are among the characteristics of Mn-Zn ferrites. These ferrites particularly in the form of magnetic nanoparticles, have garnered significant interest in cancer research and therapy and the biomedical field. Researchers are keenly interested in the …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 2, 2024 · pp. 15–26 Read article
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Investigation of bio-physical interaction between Nanoparticles, Colloids, and biomolecules: Pharmaco-medical application.
Abstract: Currently, research into magnetic nanoparticles has become Popular. The fundamental principle involving the physics of magnetic nanoparticles is its interaction with biomolecules such as hemoglobin, DNA, and RNA. In this research, the nature Vander walls interactions, electrostatic repulsion, thermal interactions, and magnetic interaction between nanoparticles and molecule is explored. The interaction parameters such as Zeta potentials between layer, magnetic moment density, and Gibbs energy can are discussed by using DLVO …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 3, 2024 · pp. 6–17 Read article
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Comprehensive Review on Sterilization Methods and Material Considerations
Abstract: The problem of environmental contamination, which is important for both public health and the economy, has been addressed through a great deal of research on the sterilization and disinfection of pollutants and microorganisms. Many types of pollutants and hazardous materials, such as microorganisms and toxic gases, are discharged into the environment and can enter the human body through ingestion, adsorption, or inhalation. Numerous respiratory conditions, strokes, lung cancer, and heart …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 2, 2025 · pp. 25–32 Read article
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Health Hazards of Nanoparticles and Environmental Pollutants
Abstract: The exponential growth in the use of nanoparticles and the prevalence of environmental pollutants have raised significant concerns regarding their health hazards. Nanoparticles, owing to their unique physicochemical properties—such as small size, high surface areatovolume ratio, and chemical reactivity—can penetrate biological barriers, including the bloodbrain barrier, and interact at the cellular and molecular levels. This can lead to oxidative stress, inflammation, and cellular dysfunction, ultimately resulting in potential toxicity. Similarly, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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Integrating Atmospheric Science: Understanding Greenhouse Gases, Aerosols, and Air Quality Dynamics
Abstract: Atmospheric science investigates the Earth’s atmospheric systems to understand their composition, dynamics, and the implications for climate, weather, and air quality. This review explores five primary areas within the field: atmospheric composition, atmospheric modeling, remote sensing, air pollution, and boundary layer dynamics, highlighting critical challenges and advancements. Rising levels of greenhouse gases (GHGs), including carbon dioxide and methane, continue to drive global warming, while feedback mechanisms—like cloud interactions and surface …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 32–35 Read article
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Hidden Gems of Dragon Fruit: Its Role in Pharmacognosy and Therapeutics
Abstract: The Cactaceae family includes the medicinal plant Hylocereus spp., also known as dragon fruit. The skin’s unique morphology, which reflects the body’s oval form, is characteristic of dragon fruit. Dry conditions are ideal for dragon fruit growth. Dragon fruit, also known as pitaya, is a fantastic functional food that has attracted attention recently due to its numerous therapeutic benefits, including antioxidant, anti-cancer, anti-diabetic, anti-microbial, hepatoprotective, and anti-hyperlipidemic properties. It also …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 92–101 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Machine Learning-Driven Early Prediction and Prevention of Obesity and Overweight
Abstract: Obesity has become a global health concern, with its prevalence reaching alarming levels in recent years. By classifying obesity-level, healthcare professionals can assess an individual's risk and develop appropriate treatment and prevention strategies. Healthcare professionals can customize interventions and create personalized treatment plans based on individual needs. This paper delivers a system provides an overview of obesity, highlighting the importance of accurate and standardized categorization for effective management and treatment …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 31–40 Read article
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Advancing Healthcare Systems: A Machine Learning Approach to Multi-Disease Prediction
Abstract: The integration of machine learning algorithms in healthcare has revolutionized the way we approach disease prediction and diagnosis. An attempt to employ machine learning techniques to forecast numerous diseases is presented in this study. A diverse dataset containing patient records, medical history, and relevant features for various diseases was used to develop predictive models. Feature selection and normalization were among the preprocessing methods used to clean and prepare the data. …
Published in Journal of Electronic Design Technology · Vol. 16, Issue 1, 2025 · pp. 1–6 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Long Non-Coding RNAs: Key Regulators of Gene Expression in Development and Disease
Abstract: Long non-coding RNAs (lncRNAs) are RNA molecules that do not make proteins but are essential for controlling how genes are turned on or off in the body. These molecules help with various biological functions, such as guiding cell growth, shaping development, and influencing the progression of diseases. Recent advancements in genomics and transcriptomics have revealed the vast and complex roles of lncRNAs, with an increasing recognition of their involvement in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article