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324 articles for “Drug delivery systems”
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Episiotomy Practice and its Associated Factors among Mothers who Gave Birth Vaginally at Public Health Institutions of Shire Town, Northern Ethiopia
Abstract: Obstetric perineal trauma is assumed to be a serious health problem for women as well as for their child during their childbirth. Episiotomy is the commonest obstetric surgical operation performed to increase the diameter of the vulvas outlet during the late period of the second stage of labor in order to facilitate vaginal delivery. The rate of episiotomy is on the decline in developed countries but still remains high in …
Published in Research and Reviews: A Journal of Health Professions · Vol. 6, Issue 1, 2016 · pp. 15–21 Read article
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Nanorobots: The Fight against Cholesterol
Abstract: Cardiovascular disease (CVD) rests leading reason of death globally, with atherosclerosis, the buildup of plaque in arteries, playing a central role. Current treatment strategies, including lifestyle changes and medications, often fall short in completely reversing or preventing the progression of atherosclerosis. This has spurred the exploration of innovative approaches, with nanorobotics emerging as a promising avenue for targeted plaque control and high-density lipoprotein (HDL) enhancement. This article discusses how nanorobots …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 2, 2025 · pp. 23–32 Read article
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A Comprehensive Study of ZnxFe2-xO3 Nanoparticles: Assessing Magnetic Properties for Medical Imaging (MI)
Abstract: Diluted magnetic ZnxFe2-xO3 nanoparticles are special semiconducting nanoparticles which are recognized for their magnetic properties. A theoretical examination of Zn-doped αFe2O3 nanostructures reveals a range of structural and property variations, offering insights into their potential applications and behavior at the nanoscale. In this regard, Heisenberg’s model and Weiss molecular filed theory is used to describe the magnetic properties of ZnxFe2-xO3 nanoparticles. These theorems inevitably enable to investigate the relationship between …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 18–25 Read article
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Medicinal Chemistry of Nanoparticles for Cancer Theranostics
Abstract: Cancer is a disease in which cells growth is uncontrollable and conventional treatment have a few side effects, for example, nonspecific delivery, unable to enter the center of tumor and absence of solubility. Nanoparticles could directly target disease cells specifically and increased medication localization in tumor cells giving exact cellular uptake. The theranostic nanomedicine can accomplish systemic flow, avoid host resistances and deliver the medication and diagnostic agents at the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 3, 2016 · pp. 28–41 Read article
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Synthesis, Characterization and Drug Delivery Application of Poly (Acid Fuchsin) Based Triblock Copolymer
Abstract: Synthesis, characterization and its drug delivery application of Poly (acid fuchsin) (PAF) was done under inert atmosphere. The (M0/I0) was maintained at 100. In order to increase the molecular weight and processability, it was block copolymerized with ε-caprolactone (CL) and tetrahydrofuran (THF) separately. The conductivity value of PAF was found to be decreased after the chemical conjugation with poly(ε-caprolctone) (PCL) and poly(tetrahydrofuran) (PTHF) blocks. Thus obtained triblock copolymer was subjected …
Published in Journal of Catalyst & Catalysis · Vol. 3, Issue 2, 2016 · pp. 33–43 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications,challenges, current trends, and reseach opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications, challenges, current trends, and research opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications, challenges, current trends, and research opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Polymer Chemistry in Dental Applications: Advances and Innovations
Abstract: Polymer chemistry has revolutionized dental materials, offering enhanced mechanical strength, durability, and biocompatibility. The integration of polymer-based materials in dentistry has led to significant advancements in restorative, prosthetic, and preventive treatments. This paper explores the role of polymers in dental applications, focusing on composite resins, denture bases, impression materials, and adhesive systems. The development and alteration of polymers have led to the creation of advanced materials with enhanced wear resistance, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 16–22 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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A Comprehensive Review Summarizing the Effect of Electrospinning Parameters and Potential Applications of Nanofibers
Abstract: Electrospinning is a valuable and effective system to create ultrafine nanofibers. Due to its flexibility, cost efficiency, in addition, the potential to be used in a broad range of uses, it has been a method of excellent science and industrial concern, bringing about a notable potential for nanotechnology. Since it is considered to be the most encouraging way of producing coherent nanofibers on a big scale, there is an enormous …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 9, Issue 3, 2019 · pp. 1–6 Read article
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article
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Quantum Mechanics: Revolutionizing Pharmaceutical Sciences
Abstract: Quantum physics and pharmacy have generally been regarded as distinct areas—one investigates the microlevel behavior of non-living matter while the other concentrates on intricate biological systems. Nevertheless, progress in life sciences has increasingly depended on molecular-level insights, whereas quantum physics has advanced beyond basic principles to impact real-world uses. This intersection provides new opportunities for, pharmacy. Quantum entanglement, which allows for instantaneous relationships between particles, can be utilized for secure …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 72–77 Read article
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Common Medicines Used for Self-Medication in Rural India–A Descriptive Study
Abstract: Background: Self-medication is a significant aspect in healthcare delivery system especially in India. Objectives: The present study focuses on the identification of the common medication used by the people in the rural community of Bangalore, India. Materials and Method: Design: The present study was a community-based, cross-sectional survey conducted among rural population. Setting: People in the selected rural community of Bangalore, Karnataka, India. Participants: Totally 110 participants were selected with …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 3, 2020 · pp. 12–17 Read article
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Computational Study of Sombor Index on Generalized Abid–Waheed Graphs for Polymer Modeling
Abstract: This study investigates the topological properties of generalized Abid Waheed graphs. Development of theoretical models in chemistry, reducing computational complexity while analysing large molecules or networks Abid Waheed graphs play a significant role. Motivated by these findings, the research was extended to encompass generalized Abid Waheed graphs, characterized by r cycles of order s. A notable similarity between Abid Waheed graphs and Jahangir graphs was observed. The potential applications of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 267–274 Read article
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Effective Antibiotics and ATP Loaded Delivery System in the Management of Diabetic Wounds
Abstract: The aim of present research work was to formulate and evaluate antibiotics and ATP-loaded delivery system (liposome) in the management of diabetic wounds. Wound is disturbance in the normal skin anatomy and their functions; tissue injury resulting in the “loss of continuity of epithelium with or without the loss of underlying connective tissue.” Wound bad is an ultimate situation for wound infection, while wound healing is a complex and dynamic …
Published in Research and Reviews : A Journal of Immunology · Vol. 3, Issue 2, 2013 · pp. 1–10 Read article
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Antibiotics Utilization Pattern in Pediatric Ward of Ghimbi Adventist Hospital, Ghimbi Town, Oromia Region, West Ethiopia
Abstract: Drug use evaluation is ongoing systematic process designed to maintain the appropriate and effective use of drugs. It is used to ensure that drugs are used appropriately, safely and effectively to improve patients’ health status. The general objective of the study was to assess antibiotics utilization patterns in pediatric ward of Ghimbi Adventist Hospital (GAH), Ghimbi town, Oromia region, West Ethiopia.A hospital-based retrospective cross-sectional study was conducted to assess the …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 19–30 Read article