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487 articles for “Drug Delivery”
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Review on Drug Nanoparticles: Special Emphasis on Herbal Nanoparticals
Abstract: Nanoparticles have greater research horizon and smaller size ranging from 1 to 1000 nm. This is very small as compared to other particles. As their size is extremely small, so ultimately their route of administration and reaching to site of action becomes more convenient. These nano-scale particles can easily pass out the cell membrane such as blood brain-barriers. Nanoparticles are synthesized from various metals, polymers, microbes and even from plant …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 48–58 Read article
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Bioenhancer to Boost Herbal Drug Efficacy
Abstract: Bioenhancers are natural substances that significantly improve the absorption, bioavailability, and therapeutic efficacy of drugs when co-administered, without showing notable pharmacological activity of their own. In herbal medicine, the concept of bioenhancement has received growing attention as many phytoconstituents exhibit low oral bioavailability due to poor solubility, limited permeability, and extensive first-pass metabolism. The traditional Ayurvedic system first introduced this concept through the discovery of Piperine, the active alkaloid from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 · pp. 01–13 Read article
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Accelerating Drug Discovery with AI: Transforming the Pharmaceutical Pipeline
Abstract: The revolutionary potential of artificial intelligence (AI) is examined in this essay the pharmaceutical industry, highlighting its application across the drug development lifecycle. Artificial Intelligence, specifically via deep learning models and machine learning (ML) such as GANs, RNNs, and transformers, enhances drug discovery, formulation, toxicity prediction, and clinical trials. It streamlines processes like identification of targets, virtual screening, modelling of structure-activity relationships, and medication repurposing. AI is also employed in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 77–84 Read article
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A Concise Overview of Recent Developments and Uses in Nano-Silica and Nanoparticles Encased in Silica
Abstract: Nano-silica and silica-coated nanoparticles have gained significant attention lately due to their exceptional chemical and physical properties, including a high surface area-to-volume ratio, adjustable porosity, thermal and chemical stability, biocompatibility, and ease of surface modification. These characteristics make them versatile materials applicable in various scientific and industrial sectors. Their ability to control particle size, shape, and surface traits allows them to be effectively utilized in catalysis, drug delivery, biosensing, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 696–704 Read article
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Overview of Recent Advancement of Nano Stent in Pharmaceutical Application
Abstract: Interventional cardiology has witnessed remarkable progress with the evolution of nanotechnology, leading to the development of nanostents. Nanostents, characterized by their nanoscale features and innovative materials, have emerged as a cutting-edge solution for addressing the limitations associated with traditional stent technologies. This thorough analysis examines the most recent developments in the design, manufacture, and use of nanostents, emphasizing how they may completely transform vascular interventions. The first section of the …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article
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From Clinic Formulation to Development of Acebrophylline
Abstract: Acebrophylline, a commonly utilized bronchodilator with anti-inflammatory properties, has become a key therapeutic option for managing respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis. This review explores the journey of Acebrophylline from its clinic formulation to its development and commercialization, focusing on the key aspects of formulation strategies, pharmacological properties, and regulatory considerations. The drug’s dual mechanism of action, which involves both bronchodilation and anti-inflammatory effects, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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Polymer Nanocomposites As Emerging Platforms in Pharmaceutical Nanotechnology
Abstract: Nanotechnology allows the handling of materials in the 1–100 nm range, where distinct physicochemical phenomena, including quantum effects and higher surface-to-volume ratio, enable disruptive uses in pharmaceuticals and biomedicine. Significant challenges in solubility, stability and targeted biodistribution of therapeutics can be overcome by incorporating nanostructured polymers and polymer-based composites into drug delivery systems. PLGA nanoparticle and other nanocarriers, such as PLGA micelles, dendrimers, and hydrogels, have revealed promising effects on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 268–278 Read article
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Thermo-Responsive Polymer Blends for Minimally Invasive Medical Procedures
Abstract: Thermo-responsive polymer blends have become a key new class of biomaterials for the minimally invasive medical procedure. They offer precision, flexibility and greater patient safety. These smart materials undergo a change of physical/ mechanical properties relative to temperature difference in the body, limiting tissue trauma and increasing effectiveness of the procedure. Their adjustable sol-gel behavior, shape-memory effects and reversible volume change provides an opportunity for their precise delivery through catheters, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Formulation Development of Otic In Situ Gel containing Lomefloxacin Hydrochloride
Abstract: The present study was aimed at formulation development of a sustained release otic in situ gel of lomefloxacin hydrochloride for the treatment of chronic suppurative otitis media. Poloxamer 407 was used as the thermoreversible gelling agent. Poloxamer concentration in the range of 15–20% w/v was tried. Poloxamer 407 at 16% w/v gave satisfactory in situ gel forming formulations as it gelled near physiological temperature. Poloxamer 407 with various viscosity enhancing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 1, 2016 · pp. 20–29 Read article
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Integration of Raspberry Pi and Arduino for an Intelligent Medicine Dispensing System in Healthcare Facilities
Abstract: "Automatic Medicine Dispenser Using QR Code" revolutionizes healthcare service delivery by minimizing queue-related inconveniences. Our project created a vending machine using QR code technology in response to the evolving healthcare and technological landscape. The system is powered by an Arduino Mega 2560 and includes key components like a DC gear motor, L298N motor driver, infrared sensor, HC05 Bluetooth module, and a 12V power supply for drug delivery. The project comprises …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 2, 2024 · pp. 33–45 Read article
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Biopolymer-Based Nanoparticles: Advances in Fabrication, Characterization, and Biomedical Applications
Abstract: The emergence of biopolymer-based nanoparticles, particularly those composed of proteins and polysaccharides, has significantly transformed the landscape of biocompatible and biodegradable materials. These nanoparticles offer immense potential due to their ability to facilitate encapsulation and targeted delivery of bioactive compounds, enhancing therapeutic efficacy while minimizing side effects. This review explores the various fabrication techniques, including emulsification, desolvation, coacervation, and electrospray drying, emphasizing their advantages and limitations. The characterization of nanoparticles …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 38–46 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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Physiochemical and Formulation Factors Affecting the Absorption of Basti Dravyas
Abstract: Basti is a purificatory process by which all the three vitiated Doshas are expelled from the anal canal and is said to be the best treatment for Vata dosha. There are two main types of Basti mentioned in Ayurveda Sneha Basti and Asthapan Basti. Compared to oral and parental route, rectal drug delivery is not so much exposed in today’s era, whereas Ayurveda highlights Basti as half of the treatment, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 1, 2017 · pp. 32–34 Read article
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Development and Characterization of Ondansetron containing Chewing Gum Formulations for Preventing Vomiting and Motion Sickness
Abstract: AbstractChewing gums are portable drug delivery devices that can deliver medications via the buccal route for either local or systemic absorption. Without water, it can be administered discretely. Antiemetic medication is combined with the gum base in medicated chewing gums, which are chewed rather than ingested. These formulations contain Ondansetron, Polyvinyl alcohol, Carboxymethyl agorase, Peppermint oil, Polyethylene glycol (PEG-400), Calcium carbonate, Synthetic gum base, Propyl paraben, and Ascorbic acid. The …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 15–28 Read article
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NANOBOTS - The Artificial Blood
Abstract: Artificial blood is simulated to biological blood to higher extent where it is expected to be used to imitate and accomplish some very important functions of natural blood. Thus, nanobots can be a good alternative to blood transfusion in case of medical emergency too. They have several advantages like possibility of highly targeted delivery which will ultimately decrease the side effects and the need for invasive steps combinedly NANOBOTS—The artificial …
Published in Trends in Drug Delivery · Vol. 5, Issue 2, 2018 · pp. 20–22 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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Current Trends about Transfersomes: Formulations, Applications and Pharmacological Interventions.
Abstract: Transfersomes are one of the novel targeted drug delivery system which includes hydrophilic molecules. Transfersomes are a type of liposomes which consists of phosphodidylcholine and an edge activator. The elastic characteristics of Transfersomes enabling it to bend and penetrate through tiny holes that is much smaller than their own size. Transfersomes has various advantages like good solubility, greater bioavailability, and better penetration through the stratum cornea through intracellular route or …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 1, 2023 · pp. 10–26 Read article
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An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites · Vol. 10, Issue 4, 2022 · pp. 32–54 Read article
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Characterization of Cellulose Producing Bacterial Isolates from Rotten Fruits
Abstract: Cellulose, the most abundant natural polymer, is predominantly sourced from plant wood but can also be synthesized by certain bacteria in the form of bio-cellulose. The potential applications of bio-cellulose are extensive, particularly in the biomedical field for tissue engineering, drug delivery, and more. The distinct properties and purity of bacterial cellulose, in contrast to plant-derived cellulose, underscore its importance and drive further research in the area. This study focuses …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 38–45 Read article