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394 articles for “Bio-agents”
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Swarm Intelligence: Nature-Inspired Problem Solving
Abstract: Swarm Intelligence (SI) is a computational paradigm inspired by the collective behavior of natural systems, such as flocks of birds, schools of fish, and colonies of ants. It involves decentralized, self- organized systems where simple agents follow simple rules, yet their interactions lead to complex global behaviors. SI has gained significant attention in recent years due to its potential applications in solving optimization problems, routing, scheduling, and artificial intelligence tasks. …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 12, Issue 3, 2025 Read article
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Synthesis and Characterization of pH-Sensitive Poly (N-isopropylacrylamide-co-acrylic Acid) Hydrogels for Controlled Release of Doxorubicin
Abstract: pH-responsive polymeric hydrogels have attracted significant attention as intelligent biomaterials for site-specific and controlled drug delivery in cancer therapy due to their ability to respond to the acidic tumor microenvironment. In the present study, poly (N-isopropylacrylamide-co-acrylic acid) [P(NIPAM-co-AAc)] hydrogels were synthesized via free radical copolymerization and systematically characterized to evaluate their suitability for controlled delivery of doxorubicin, a widely used chemotherapeutic agent. The copolymer hydrogels were prepared using N-isopropylacrylamide and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 449–458 Read article
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Therapeutic Potential of Terminalia arjuna Bark in the Management of Hemorrhoids: A Comprehensive Review
Abstract: Background: Hemorrhoids appear frequently among anorectal disorders since they create vascular swelling together with pain symptoms, while leading to bleeding and mucosal tissue tending to slide out. Though effective therapy exists, traditional treatments produce various adverse effects and lead to recurrence and inconsistent patient following of medical recommendations over the long term. Plantbased therapeutic medicines have gained rising demand, which leads experts to investigate medicinal plants with established pharmacological effects. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
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Breeding Strategies of Self Pollinated Crop with Special Emphasis on Hybrid Rice: Present and Future Perspectives
Abstract: AbstractDevelopment of hybrid cultivar in crop plants is a remarkable success of plant breeding. Hybrid breeding technology is greatly applied in cross pollinated crop and is limited in autogamous self pollinated crop due to strict genetic makeup of plant and floral biology. Development of genetic male sterility system in various crop plants has overcome the problem of tedious hand emasculation. Cytoplasm genetic male sterility has been widely applied in hybrid …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 3, Issue 3, 2014 · pp. 1–3 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Review on Advanced Molecular Diagnostic Tools and Their Applications
Abstract: Although the diagnosis of diseases is still primarily based on conventional methods (staining, culture, biochemical analysis), a series of advanced molecular diagnostic tools are increasingly introduced and incorporated in the workflow of clinical laboratories worldwide. These tools, such as polymerase chain reaction, northern blotting, restriction length polymorphism, flow cytometry, southern blotting, fluorescent in situ hybridization, agarose gel electrophoresis and pyrosequencing that are based on either the properties of nucleic acids …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 21–33 Read article
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Comprehensive Review of Kojic Acid and Its Derivatives: Biological Activities, Safety, and Therapeutic Potential in Depigmentation
Abstract: There are several uses for kojic acid in human medicine, particularly in depigmentation. Additionally, derivatives of it are suggested to enhance efficacy, avoid side effects, and stop chemical degradation. With an eye toward human use and an attempt to clarify the action mechanisms, the goal of this study was to review the most recent scientific literature regarding the biological activities and safety information of kojic acid or its derivatives. During …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 45–53 Read article
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Ferrocenium Ion Encapsulated Montmorillonite Clay as a Voltammetric Sensor for Distinguishing Amino Acids Glycine and Alanine
Abstract: Detection and determination of small bio-molecules and metal ions are of great importance for diagnosis of a number of diseases and understanding environmental pollution leading to extensive research on development of sensors. Among different sensors, electrochemical sensors are unique because of simplicity, low cost, easy maintenance and easy in vivo applications. Voltammetric sensor, one of the major constituents of electrochemical sensors, is essentially a surface modified working electrode (WE). The …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 1, 2018 · pp. 8–11 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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Eco-Friendly and Sustainable Furniture in Interiors
Abstract: In the realm of interior design, the imperative for sustainability has become increasingly pronounced. "Sustainable Materials and Design: Shaping the Future of Furniture for a Greener Planet" explores the pivotal role of interior designers in advancing sustainable practices and innovative design solutions within the furniture industry. This paper delves into the environmental challenges inherent in traditional furniture manufacturing methods and materials, underscoring the need for transformative change. Through an examination …
Published in International Journal of Sustainability · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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Synthesis, characterization, and antibacterial activity of silver nanoparticles with expired minocycline as reducing agent: proposed as a recycling technique.
Abstract: In this research, expired minocycline, a broad-spectrum tetracycline antibiotic, was employed as both a reducing and stabilizing agent for the eco-friendly synthesis of silver nanoparticles. This sustainable method avoids the use of toxic chemical reducing agents, providing a greener alternative for nanoparticle production. The synthesized silver nanoparticles were analyzed using several characterization techniques, such as UV-Vis’s spectroscopy, scanning electron microscopy, transmission electron microscopy, and Edex analysis, to assess their structural, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 30–43 Read article
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"Onychomycosis in the Indian Subcontinent: Clinical, Microbiological and Therapeutic Perspectives,”
Abstract: Onychomycosis is a chronic fungal infection of the nail unit involving the plate, bed, and matrix, accounting for a substantial proportion of nail disorders encountered in dermatology practice worldwide. In South Asia—particularly India, Pakistan, Bangladesh, and Nepal—the burden is amplified by a convergence of climatic, socioeconomic, and healthcare-related factors. Hot and humid environmental conditions, widespread dermatophytosis, occlusive footwear practices, chronic wet work, and limited access to specialized mycological diagnostics contribute …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 Read article
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Natural Antibodies Against Enteromicrobes and their Toxins for the Treatment of Rheumatoid Arthritis
Abstract: Autoimmune diseases (ADs) are thought to be brought on by the host immune system accidentally attacking and destroying its own tissue. “Molecular mimicry,” which asserts that antibodies against an infectious agent cross-react with a self-antigen possessing an identical or similar antigenic epitope, is a generally recognised theory to explain the pathogenic mechanism of ADs. This theory, however, was probably developed using false antibody assay data that was heavily impacted by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 3, 2022 · pp. 1–12 Read article
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Identification of Specificity Determining Positions through Phylogenetic Studies and Molecular Modeling of ICP27 as a Drug Target of Herpes Simplex Virus-1
Abstract: An ever-growing effort to apply computational power to the combined chemical and biological space in order to streamline drug discovery, design, development and optimization can be achieved through computational approaches. Herpes simplex is an infection that is caused by a herpes simplex virus (HSV), and is one of the most common human infections transmissible to a body site. Infection with HSV can result in several diseases ranging from apparent infections …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 1, 2015 · pp. 32–43 Read article
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Enhancing Mechanical Properties of Fiber-Reinforced Composites Through Sorghum Husk and Unsaturated Polyester Resin.
Abstract: Plastic, a versatile synthetic polymer, holds considerable significance and utility in human society due to its manifold applications. However, its deleterious ecological ramifications have spurred growing apprehensions. This has galvanized the pursuit of ecologically amicable substitutes, propelling interest in the domain of composite materials. Composites are formulated by amalgamating diverse substances, and in this context, Styrene Diluted Unsaturated Polyester Resin (SDUPR) is melded with natural constituents. Among these organic constituents, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 59–65 Read article
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Black Tea: Leveraging Human Health from Indian Perspective
Abstract: Tea, the most preferred drink in the world after water, has been under intense research in recent years due to its fascinating chemical composition. Major polyphenolic compounds— theaflavins (TF), residual catechins, thearubigins as well as theanine and caffeine—present in black tea (BT) contribute to color, distinctive flavor and play significant roles both for quality of tea and act as a safeguard against many ailments. Antioxidants present in BT act against …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 53–60 Read article