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320 articles for “system biology”
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Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article
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Synthesis, characterizations, and challenges of magnetic Zn x Fe 2-x O 3 nanoparticles
Abstract: Diluted magnetic semiconductors comprising magnetic nanoparticles are a driving force in a variety of applications, including biomedicine, bioelectronics, photocatalytic activities, and nanosensors. However, the functionality of these nanomaterials can be influenced by several factors, such as synthesis route, characterization procedures, source, crystal size, and morphology. In this research, emphasis is devoted to synthesizing and characterizing magnetic nanoparticles. Most importantly, it is focused on biological methods, Co-precipitation methods, hydrothermal Gravity methods, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 · pp. 1–16 Read article
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Investigation of Bio-Physical Interaction and Electrophoretic Properties of Fe3O4/DNA Nanocomposite and Colloids for Biomedical Application
Abstract: In recent years, research on magnetic nanoparticles has gained significant attention. The core concept behind their physics lies in their interaction with biomolecules such as hemoglobin, DNA, and RNA. This study examines the fundamental forces involved in these interactions, including van der Waals attractions, electrostatic repulsion, thermal effects, and magnetic coupling between nanoparticles and biological molecules. To describe these interactions quantitatively, parameters such as zeta potential, magnetic moment density, and …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 3, 2025 · pp. 20–32 Read article
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Synthetic and Natural Polymer Composites in Wound Healing and Drug Delivery
Abstract: Both man-made and natural polymer mixtures have become important materials in wound repair and medicine delivery because they can be used in many ways and work well with living things. The benefits of both man-made and natural polymers are combined in these composites. They have a wide range of mechanical, chemical, and biological qualities that make them useful for many medical uses. In wound healing, polymer mixtures help tissues grow …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 466–478 Read article
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Triple Negative Breast Cancer—Pattern of Recurrence and Survival: A Single Institute Experience
Abstract: Triple negative breast cancer (TNBC) is a distinct biological entity and recent data shows it as a heterogeneous group with at least 6 subtypes with differences in clinical outcome.This study intends to analyze the prevalence, recurrence pattern and outcome of triple negative breast cancer in our patient cohort.We reviewed the outcomes of 244 consecutive triple negative non-metastatic breast cancer patients who were treated with a radical intent from Jan 2004 …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 3, 2017 · pp. 5–8 Read article
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Cosmeceuticals: Integrating Therapeutic Functionality into Cosmetic Science
Abstract: Cosmeceuticals are a quickly growing group of skincare products that are in between cosmetics and drugs. These products have biologically active components that are said to provide medical or drug-like advantages for a number of skin problems, including ageing, hyperpigmentation, acne, and damage from the sun. Cosmetics are not medications, but cosmeceuticals are made to affect skin function at the cellular level. This article talks about what cosmeceuticals are, how …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 19–35 Read article
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Neuromorphic Spiking Neural Networks and Event-Driven Hardware: Architectures, Learning Paradigms, and Experimental Realizations
Abstract: With the current computational boom the research community is seeking for more sustainable energy efficient i.e. biologically inspired models of conventional Artificial Neural Networks (ANNs). Spiking Neural Networks (SNNs) known as the third generation of neural network models, provide a revolutionary approach by mimicking the asynchronized event-driven and temporally accurate signaling of the mammalian brain. Whereas conventional deep learning models operate with real-valued activations and dense matrix multiplications, SNNs use …
Published in Current Trends in Signal Processing · Vol. 16, Issue 2, 2026 · pp. 39–46 Read article
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Sustainable Cotton Crop Productivity through Precision Weed Detection: A Deep Learning-Based Approach with UAV Integration
Abstract: Weeds present a major challenge to crop productivity by competing with crops for vital resources, including water, sunlight, and nutrients, often resulting in significant yield reductions. On a global scale, weeds are responsible for approximately 13.2% of annual crop losses, a quantity sufficient to feed nearly one billion people. These invasive plants disrupt agricultural systems and adversely impact crop yields. Given their uneven distribution in fields, ground or aerial robots …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 19–26 Read article
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Phytoconstituents of Ticanto crista (L.) R. Clark & Gagnon (Caesalpiniaceae): A Review
Abstract: Ticanto crista (L.) R. Clark & Gagnon (= Caesalpinia crista L.), a member of the Leguminosae family, is a medicinally important plant traditionally used in various systems of medicine, including Ayurveda, for treating a wide range of ailments. It has attracted increasing scientific interest due to its rich phytochemical profile and therapeutic potential. This review serves as a comprehensive index of the chemical structures of common and medicinal compounds isolated …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 3, 2025 · pp. 38–59 Read article
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Nanoparticles in Cutting-edge Healthcare: Current Use and Emerging Issues
Abstract: Nanoparticles are sub-micron-sized particles (less than 100 nm on average). Using these materials as contrast agents in imaging and as carriers for medication and gene transfer into malignancies has given them a prominent place in contemporary medicine. Nanoparticles allow for previously inconceivable levels of analysis and therapy. However, nanoparticles provide new societal and environmental challenges, especially regarding toxicity. In this overview, we discuss how nanoparticles have benefited contemporary medicine and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 105–118 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Artificial Intelligence in Healthcare for Implants and Tissue Regeneration: Advances, Challenges, and Future Directions
Abstract: Artificial intelligence (AI) has been a revolutionary influence in contemporary healthcare, especially in implant design, biomaterials research, and tissue regeneration. In regenerative medicine, AI facilitates predictive modeling, optimization, and decision-making via the analysis of intricate biological, material, and clinical information. This study analyzes current research on AI applications in implant technologies and tissue regeneration, specifically addressing scaffold engineering, biomaterial characterisation, stem cell and gene treatments, smart biomaterials, and implant planning. …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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Studies of CRISPR/CAS 9 Gene Interactions in Streptococcus pyogenes
Abstract: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/cas9/single guide RNA (sgRNA) system is a DNA editing system in mostly studied in prokaryotes. Studies of CRISPR/cas9 gene interactions in Streptococcus pyogenes has been conducted using in silico approaches in the present research. Proteins like DNA polymerase I (polA), NAD-dependent DNA ligase LigA (ligA), Translaldolase (tal), Thymidine kinase (tdk), Streptococcal exotoxin I (speI), Phage associated protein (SPy_0679) and Hypothetical proteins like SPy_1047, SPy_1048, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 32–38 Read article
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Systematic Analysis of the Pharmacological Properties of Different Plant Parts of Madhuca sp.
Abstract: Madhuca sp., a perennial tree belonging to the Sapotaceae family, is widely distributed across South and Southeast Asia. It holds considerable value across the food, beverage, and pharmaceutical sectors. The growing interest among cultivators, agronomists, and industry stakeholders stems from the diverse bioactive potential documented across different parts of the plant, including the bark, leaves, seeds, and flowers. Traditional and emerging evidence points to a wide spectrum of pharmacological actions, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 1–11 Read article
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Exploring Family Systems Therapy (FST) in Substance Dependence
Abstract: This paper intends to explore how family systems therapy (FST) can be utilized to address substance dependence issues. Substance abuse not only affects the individual but also impacts the extended family members' physical, emotional, and psychological health. The substance use disorder (SUD) not only has an impact on the individual, but also influences family members. This narrative review provides an examination of the connection between substance dependence and the family …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 9–26 Read article
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Polymeric Microfluidic Chips for Rapid Point-of-Care Diagnostic Testing
Abstract: Polymeric microfluidic chips have emerged as promising platforms for rapid point-of-care (POC) diagnostic testing by integrating sample preparation, fluid manipulation, biochemical reactions, and signal detection within compact and potentially low-cost devices. Their compatibility with materials such as polydimethylsiloxane (PDMS), polymethyl methacrylate (PMMA), cyclic olefin copolymer (COC), polystyrene (PS), polycarbonate (PC), and polymer–paper composites provide considerable flexibility in device design and manufacturing. Advances in soft lithography, injection moulding, hot embossing, laser …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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The Role of Guduchyadi Rasayana In Mental Well-Being – A Review Study
Abstract: In this era, stress is the main etiological factor behind almost every other disease. In 2020, the COVID-19 pandemic led to a notable increase in anxiety and depressive disorders worldwide. This highlighted the critical need for mental health support during such challenging times. Ageing is a biological process characterized universally by natural degeneration, standing out as a significant risk factor for morbidity and mortality. The Oxidative Stress Theory suggests that …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 22–30 Read article
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A Comprehensive Review of Alternative Medicine: Biological Plausibility, Testability, Repeatability, and Effectiveness
Abstract: Alternative medicine, encompassing practices, such as acupuncture, herbal remedies, homeopathy, chiropractic care, Ayurveda, and Traditional Chinese Medicine (TCM), has gained global popularity as patients seek non-conventional healthcare solutions. Despite its widespread use, scientific evaluation of its biological plausibility, testability, repeatability, and effectiveness remains a significant challenge. This review critically examines these four criteria to assess the validity and reliability of alternative therapies. Acupuncture demonstrates partial plausibility, with evidence suggesting its …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 32–46 Read article