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474 articles for “clinical studies”
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Pneumonia Detection and Classification Using Deep Learning
Abstract: Pneumonia, an infectious lung disease primarily caused by bacteria, often exacerbated by environmental factors, leads to the accumulation of pus in the lung’s alveoli. Accurate diagnosis through chest X-rays, ultrasounds, or lung biopsies is crucial to avoid misdiagnosis and ensure proper treatment, crucial for patients’ quality of life. Diagnostic capacities have been greatly improved by deep learning advances, especially with convolutional neural networks (CNNs). This research presents a robust CNN-based …
Published in Journal of Microwave Engineering and Technologies · Vol. 11, Issue 3, 2024 · pp. 9–19 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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A Trends in Dietary Supplement Related to Exercise Nutrition
Abstract: A product made to address physiological or nutritional demands that might occur during sports activity is called a dietary supplement. It could offer a convenient method for fulfilling specific nutritional needs during exercise, or it could be utilized to prevent or address common nutritional deficiencies experienced by athletes. It is crucial to include the supplement in a thorough plan for the best possible sports nutrition or clinical care of nutritional …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article
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Emerging Digital Trends in Virology Software: Optimizing Viral Discovery, Surveillance,and Patient Management.
Abstract: Virology and antiviral therapeutics are being reshaped by rapid advances in computational tools, automation platforms, and virus-focused digital health applications. Software systems now span the entire virology value chain, from in silico viral target identification and antigen design, to AI-supported clinical trial management for vaccines and antivirals, to post-marketing pharmacovigilance and patient-facing mobile tools. This review examines current and emerging software trends relevant to virus studies, emphasizing applications in viral …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 29–38 Read article
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Al-Razi’s Anatomical Insights: A Detailed Review of Kitab Al-Mansuri
Abstract: Al-Razi (865–925 CE), a leading physician of the Greco-Arab Golden Age, made foundational contributions to human anatomy through clinical observation and empirical analysis. This review explores Al-Razi's anatomical insights, particularly as recorded in his influential medical compendium Kitab al-Mansuri (The Book of Medicine Dedicated to al-Mansur). In this work, Al-Razi challenges the prevailing Galenic doctrines by prioritizing evidence-based understanding over uncritical acceptance of ancient texts. His method reflects a scientific …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 1–7 Read article
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Stiff Person Syndrome: Advances in Understanding, Diagnosis, and Treatment of a Rare Autoimmune Disorder
Abstract: Stiff Person Syndrome (SPS) is a rare and complex autoimmune neurological disorder characterized by progressive muscle stiffness, rigidity, and painful spasms. This chapter provides a comprehensive overview of SPS, exploring its pathophysiology, clinical presentation, diagnostic challenges, and current treatment approaches. We discuss the latest research findings, including the role of autoantibodies, genetic factors, and environmental triggers in the development of SPS. The chapter examines various diagnostic methods, emphasizing the importance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 35–43 Read article
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Development and Fabrication of Biohydrogel for Targeted Delivery of Delafloxacin for Bacterial Skin Infections
Abstract: The escalating challenge of bacterial resistance necessitates innovative drug delivery systems to enhance the efficacy of antibiotics. This study focuses on the development and optimization of a biohydrogel formulation for the targeted delivery of Delafloxacin, aiming to improve its therapeutic outcomes against resistant bacterial strains. Utilizing a 3² factorial design, biohydrogel formulations incorporating Poly(N-isopropylacrylamide) (PNIPAM) and Genipin were synthesized. The optimization process was guided by Design Expert software, focusing on …
Published in Research & Reviews: A Journal of Drug Design & Discovery Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Cardiac Structural and Functional Changes in Anaemia: A 2D Echocardiographic Study in an Indian Population
Abstract: Anemia is a widespread global health concern, particularly prevalent in developing countries, like India, where it contributes significantly to cardiovascular morbidity. This study aimed to evaluate cardiac structural and functional changes in anaemic patients using 2D echocardiography and to assess correlations between haemoglobin levels and echocardiographic parameters. A cross-sectional observational study was conducted on 125 anaemic patients (defined as haemoglobin <13 g/dL in males and <12 g/dL in females) at …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 39–44 Read article
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A Conceptual Framework for AI-Integrated Metabolomics in Predictive Health Systems for Resource-Constrained Environments
Abstract: The increasing prevalence of non-communicable diseases (NCDs) continues to place a significant strain on healthcare systems, particularly in low- and middle-income regions where access to early diagnostic infrastructure is limited. Conventional healthcare approaches remain largely reactive, often detecting diseases at advanced stages when treatment effectiveness is reduced. This challenge underscores the need for predictive, cost-effective, and data-driven healthcare solutions. This study presents a conceptual framework that integrates metabolomics with artificial …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Development of a Polymeric Detection System for Salivary Annexin-1: A Potential Tool for Point-of-Care Diagnostics in Periodontal Disease
Abstract: Salivary annexin-1, a protein with anti-inflammatory properties, has emerged as a potential biomarker for periodontal disease. However, current detection methods, like ELISA, are often complex and require laboratory settings. This study explores the development of a novel polymeric detection system for the rapid and sensitive identification of salivary annexin-1. This system could leverage the unique properties of polymers to create a point-of-care diagnostic tool for: (1) early detection and monitoring …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 101–110 Read article
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Diabetes Risk & Al Nutrition Assistant
Abstract: The rising prevalence of diabetes mellitus has emerged as a major global health challenge. Early identification of individuals at risk, combined with personalized lifestyle-based interventions, can significantly reduce future complications. This study presents an AI-driven Nutrition Assistant integrated with a Diabetes Risk Prediction model. The system uses a machine learning classification approach to estimate the likelihood of diabetes based on clinical and nutritional factors, including body mass index, glucose levels, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 31–38 Read article
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Early Alzheimer’s Disease Prediction Using Vision Transformers and Attention-Guided MRI Analysis
Abstract: Alzheimer’s Disease (AD) continues to be a major global health concern, with early detection being crucial for effective intervention. While conventional machine learning and convolutional neural network (CNN) approaches have made notable progress in automated AD diagnosis using MRI data, they often struggle with capturing long-range dependencies and maintaining spatial contextual awareness. In this research, we propose a novel framework using Vision Transformers (ViTs) for early Alzheimer’s prediction from 3D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 30–40 Read article
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Impact Of Nurse-Led Pain Management Protocol On Postoperative Recovery Outcome
Abstract: Postoperative pain remains a critical determinant of recovery outcomes, influencing patient satisfaction, complication rates, and overall healthcare utilization. Nurse-led pain management protocols have emerged as an evidence-based strategy to enhance postoperative care through continuous assessment, individualized interventions, and multidisciplinary collaboration. This article explores the impact of nurse-led pain management on postoperative recovery outcomes, including pain reduction, early mobilization, decreased hospital stay, and improved patient satisfaction. Evidence from recent studies demonstrates …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Evaluating the Role of Apple Cider Vinegar in Managing Semaglutide-Induced Gastrointestinal Disturbances: A Systematic Review
Abstract: Background: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is highly effective in treating type 2 diabetes and obesity. However, its use is often associated with gastrointestinal side effects, including nausea, vomiting, and diarrhea, which may impact patient compliance. Objective: This systematic review aims to evaluate the evidence regarding the management of semaglutide-induced GI symptoms and assess the potential role of apple cider vinegar (ACV) as a complementary treatment. Methods: A …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article