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384 articles for “bi-directional”
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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Natural Language Processing in Education: A Review of Applications, Challenges, and Future Directions
Abstract: Natural Language Processing (NLP) has increasingly become a transformative force within the field of education, offering innovative solutions and reshaping traditional methods of teaching, learning, assessment, and educational research. This review explores the evolving landscape of NLP applications in education, shedding light on significant advancements, ongoing challenges, and emerging opportunities. The integration of NLP into intelligent tutoring systems has enabled more personalized learning experiences, while automated assessment tools have enhanced …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 2, 2025 · pp. 11–18 Read article
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E-Commerce Platform for Agricultural Products
Abstract: The e-commerce platform for agricultural products reported here is designed to solve the problems faced by shop owners, such as managing data, billing, and selling products. In many rural areas, awareness of technology is still low. By introducing this project, rural shopkeepers can learn to use new technologies, making their work easier, faster, and more efficient. Our platform specifically targets village shopkeepers, aiming to help them improve profits. It includes …
Published in E-Commerce for Future & Trends · Vol. 12, Issue 2, 2025 · pp. 28–34 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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VHDL-Based Strategies for Protecting IoT Devices from Power and Electromagnetic Side-Channel Attacks: A Study
Abstract: The environment of the Internet of Things (IoT) is rapidly developing, linking billions of devices across a wide variety of disciplines. Furthermore, despite the fact that it provides an unprecedented level of convenience and efficiency, this interconnection also presents a fertile ground for security weaknesses. Side-channel attacks, also known as SCAs, are one of the dangers that pose a considerable risk. These attacks specifically target the cryptographic implementations that are …
Published in Recent Trends in Electronics Communication Systems · Vol. 12, Issue 3, 2025 · pp. 30–40 Read article
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Investigating mosquito innate immune defence mechanism towards malaria vaccine development
Abstract: Mosquito-borne diseases weigh heavily on public health across the globe. The mosquito’s innate immune system certainly decides whether malaria parasites survive inside the vector, and that sighted it as a logical place to discover new vaccine ideas. In this review, we examine how Anopheles mosquitoes defend themselves against Plasmodium parasites and how those defenses could be turned into tools for malaria control. We focus on three layers of immunity: antimicrobial …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 50–54 Read article
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A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery
Abstract: Nanotechnology has become a groundbreaking strategy in cancer therapy, especially in drug delivery systems, offering improved treatment effectiveness while minimizing the adverse effects associated with traditional methods. This review presents an in-depth analysis of recent progress in nanotechnology for cancer drug delivery, emphasizing the design, mechanisms, and practical applications of nanoparticle-based systems. Nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, offer unique advantages, including improved drug solubility, targeted delivery to …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 24–33 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Space Pharmacy for Human Space Exploration: Overcoming Drug Stability, Packaging Challenges, Pharmacokinetic Variations, and Developing Innovative On-Demand Therapeutic Solutions for Long- Duration Missions Beyond Earth
Abstract: As humankind prepares for prolonged space exploration and the establishment of lunar and Martian habitats, ensuring reliable access to safe and effective medicines has emerged as a critical challenge. The evolving discipline of space pharmacy addresses the unique pharmaceutical needs of astronauts in microgravity and radiation-rich environments, where drug stability, packaging, and pharmacokinetics are markedly different from conditions on Earth. Traditional dosage forms often undergo accelerated degradation, while altered fluid …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 32–47 Read article
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4D Printing in Drug Delivery: Application of Shape- Morphing Materials in Controlled Drug Release
Abstract: Four-dimensional printing technology has transformed the pharmaceutical landscape, offering unprecedented opportunities for innovation in drug development and delivery. This emerging technology enables the creation of complex geometries and customized structures, facilitating the design of personalized medications tailored to individual patient needs. Personalized dosing and drug release profiles, customized pill shapes and sizes for improved swallowability. Enhanced drug solubility and bioavailability, rapid prototyping and testing of pharmaceutical products. Development of complex …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 08–16 Read article
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Nanomaterial Embedded in Sensor Technology: A New Era of Sensing Solutions
Abstract: The emergence of nanotechnology has catalyzed remarkable advances in sensor technology, leading to the development of highly sensitive and selective devices critical for a wide range of uses, from environmental monitoring to biomedical diagnostics. Nanomaterials, characterized by unique physical and chemical properties at the nanoscale, serve as effective building blocks for these sensors. This article explores the incorporation of nanomaterials in sensor technology, detailing their operational mechanisms, benefits, and challenges. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 13–23 Read article
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Mechanisms of Crystal Growth: From Spiral Steps to Surface Adhesion
Abstract: Crystal growth is a complex interplay between thermodynamic stability and kinetic processes, influenced heavily by the conditions under which crystallization occurs—particularly the degree of supersaturation. This abstract outline three principal regimes of solution-grown crystal growth: defect-driven, two-dimensional, and adhesive growth. At low supersaturation, growth is facilitated at surface defects, such as screw dislocations, where energy barriers to attachment are minimized. This results in the formation of spiraling steps that propagate …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 46–31 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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Portable and User-friendly Air Watch System Based on IoT
Abstract: The internet of things (IoT) based air monitoring system is a novel approach to monitoring air quality in real time. With the increasing concerns over pollution and its impact on human health, our IoT-based air monitoring system offers a solution to gather and analyze air quality data efficiently. The system utilizes IoT devices like Node MCU and sensors like MQ135 and DTH11 to collect data such as temperature, air quality, …
Published in Journal of Control & Instrumentation · Vol. 15, Issue 3, 2024 · pp. 19–27 Read article
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Advances in Nanotechnology-based Biosensors: Enhancing Sensitivity and Specificity in Biomedical Diagnostics
Abstract: This study provides an in-depth exploration of the rapidly evolving field of nanotechnology-based biosensors, emphasizing their significant impact on biomedical diagnostics. The integration of cutting-edge nanomaterials, including nanoparticles, nanowires, and quantum dots, has catapulted biosensing technology to new heights, yielding unprecedented gains in sensitivity and specificity, and revolutionizing the detection of biomolecules. The study highlights various types of nanobiosensors, including optical, electrochemical, and magnetic, each offering unique advantages for detecting …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 26–32 Read article
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CMOS-Based Process-Scalable Analog Circuits for Machine Learning: A Comprehensive Review and Future Directions.
Abstract: Analog computing techniques are gaining attention for machine learning (ML) applications due to their ability to reduce computational complexity. Continuous operations such as addition and subtraction offer a simpler and more efficient approach compared to probabilistic product decoding, which can be sensitive to noise and inconsistent measurements. This paper presents a simulated VLSI implementation of a broadcast edge connection, independent of the MOS component model, along with experimental results. The …
Published in Journal of VLSI Design Tools and Technology · Vol. 15, Issue 1, 2025 · pp. 8–17 Read article
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Luxury Interior Design Trends and Market Dynamics
Abstract: The luxury interior design industry is undergoing a dynamic transformation due to shifting consumer preferences, technological innovations, and a growing focus on sustainability. This research paper examines the latest trends influencing luxury interior design, including the use of eco-friendly materials, smart home technologies, biophilic design elements, and custom-made furniture. Italsoanalyzesthemarketdynamics,includingthecurrent market size, growth projections, consumer behavior, and regional variations. The paper explores how global events, especially the COVID-19 pandemic, have …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 1, 2024 · pp. 01–11 Read article
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Artificial Intelligence in Entomology: Global Advances, Applications, and Future Directions in Insect Research and Pest Management
Abstract: Artificial Intelligence (AI) is transforming entomology by enabling scalable, data-driven approaches to insect identification, ecological monitoring, and sustainable pest management. This review synthesizes recent global advances in AI applications across taxonomy, behavioral ecology, predictive modeling, and precision agriculture. Machine learning and deep learning techniques—including convolutional neural networks, acoustic classification models, and ensemble predictive algorithms—have demonstrated high classification accuracies (often exceeding 90% under controlled conditions) and improved early detection of pest …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 29–40 Read article
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A Combined ECG and PPG Signal Powered Artificial Intelligence-Based Prediction Model for Stroke
Abstract: Stroke is one of the most common causes of morbidity and mortality around the world, and emphasis on prevention and early detection strategies cannot be overstated. This review aims to integrate techniques of artificial intelligence with electrocardiogram and photoplethysmogram signals to enhance stroke prediction and monitoring of cardiovascular health. All in all, the application of artificial intelligence that incorporates machine learning, deep learning, or hybrid models gives robust tools toward …
Published in Journal of Control & Instrumentation · Vol. 16, Issue 2, 2025 · pp. 18–26 Read article
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Healthcare IT Innovations: Blockchain Technology for Healthcare Data Security and Privacy
Abstract: The healthcare sector has undergone a significant digital transformation, leading to the generation and sharing of vast quantities of sensitive medical data. While this digitization has improved patient care and outcomes, it has also introduced critical challenges related to data security and privacy. The increasing rate of data breaches in healthcare puts patient confidentiality at risk, mainly leading to identity theft, financial fraud, and loss of public trust in healthcare …
Published in International Journal of Information Security Engineering · Vol. 3, Issue 2, 2025 · pp. 01–12 Read article