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1375 articles for “Pre-clinical”
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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Beyond Conventional Membranes: Advanced Functional Platforms for Precision Healthcare and Biomedical Applications
Abstract: Traditional membrane technologies have historically been used as passive separation barriers in filtration, purification, and biomedical applications. Recent progress in nanotechnology, biomaterials, bioengineering, and surface modification has revolutionised membranes into dynamic, intelligent, and multifunctional platforms that can sense, regulate, and engage with biological systems. These sophisticated functional membranes provide unparalleled prospects for precision medicine by facilitating targeted drug administration, bio sensing, tissue restoration, organ assistance, diagnostic uses, and individualised therapy …
Published in International Journal of Membranes · Vol. 3, Issue 2, 2026 Read article
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Clinical Evaluation of Vaginal Contraceptive Cream of Sapindus mukorossi, CONSAP: A Pilot Study
Abstract: Sapindus mukorossi also known as reetha is well known herb in ancient Ayurveda. The fruits of this herb contain saponins which showed excellent spermicidal activity in vitro and in vivo animal experiments. The formulation in the form of cream was prepared for human application. The safety and tolerability pilot clinical study was organized. The aim of the present study was to evaluate the contraceptive safety and efficacy of 2.5% cream …
Published in Trends in Drug Delivery · Vol. 2, Issue 3, 2015 · pp. 22–24 Read article
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Preparation of a Novel Polyherbal Hair Dye Formulation: Better Coloring and Protection Offered as Compared to Marketed Products
Abstract: Synthetic dyes contain permanent coloring agents such as aromatic diamine, amino compounds (4-amino-2-hydrosytoluene, meta-aminophenol, etc.), hydric phenols, polycompounds (para-phenylenediamine) which results in many side effects such as skin irritation, erythrema, loss or damage of hair, and even skin cancer. Dyes obtained from various plant sources are simply available, economical, safe, competent, and rarely have side-effects. In traditional systems of medicines such as Ayurveda, Unani, Siddha, and Homeopathy, the prescribed dyes …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 11–15 Read article
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Importance of Clinical Evaluation in Nasopalatine Duct Cyst: A Case Report
Abstract: Present case report shows the importance of proper history taking, clinical evaluation such as swelling in the midline of the anterior palate, midline diastema and radiographical diagnostic aid like cone beam computed tomography which revealed a large well circumscribed oval shaped or heart shaped periapical radiolucency, resorption of antero-medial cortex of naso-palatine canal with an involvement of neighboring anatomical structures like upper impacted incisors helps in proper diagnosis of non-odontogenic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 1, 2016 · pp. 7–11 Read article
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Composition and Therapeutic Applications of Goat Milk and Colostrum
Abstract: Goats are categorized under the small ruminants which required less fodder and a small area for shelter. Both goat milk (GM) and colostrum (GC) are secreted from the mammary glands of goats. The level of nutritional and bioactive components found to be at an elevated level in colostrum within 72 hours, which reach a normal level as the time increases from parturition. Recently an increased interest in goat milk and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 10, Issue 2, 2021 · pp. 1–7 Read article
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Thermo-Responsive Polymer Blends for Minimally Invasive Medical Procedures
Abstract: Thermo-responsive polymer blends have become a key new class of biomaterials for the minimally invasive medical procedure. They offer precision, flexibility and greater patient safety. These smart materials undergo a change of physical/ mechanical properties relative to temperature difference in the body, limiting tissue trauma and increasing effectiveness of the procedure. Their adjustable sol-gel behavior, shape-memory effects and reversible volume change provides an opportunity for their precise delivery through catheters, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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A Review Article on Clinical Pharmacy Overview
Abstract: Clinical pharmacy is the branch of pharmacy and is the practice that helps the pharmacist provide services to promote rational and economical drug therapy that it’s appropriate, safe and cost effective which successively optimizes the utilization of medication and promote wellness, health and disease prevention. The reason for emergency of clinical pharmacy practice has been remarkably consistent worldwide. Clinical pharmacist provide care for patients altogether health care setting, clinical pharmacist …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 06–12 Read article
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Development of a Machine Learning and Artificial Intelligence Based Model Aimed at Forecasting the Prognostic Impact of C-Reactive Protein in Myocarditis
Abstract: The specific role of inflammation markers in myocarditis remains uncertain. We investigated the diagnostic and prognostic significance of C-reactive protein (CRP) levels at the initial diagnosis among myocarditis patients. Our retrospective study enrolled patients clinically suspected (CS) or biopsy-proven (BP) with myocarditis, with available CRP data at diagnosis. We collected patient information, including clinical, laboratory, and imaging findings at diagnosis and follow-up visits. We utilized machine learning methods, specifically random …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 12–24 Read article
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Successful Treatment of Clinical Ketosis in Dairy Cattle
Abstract: Ketosis is a post-parturient metabolic disease encountered in high yielders due to imbalance in production and feeding leading to gluconeogenesis along with formation of abnormally high levels of ketone bodies. The disorder is particularly seen within the first few weeks after calving. It arises due to a negative energy balance when energy demands for milk production exceed dietary energy intake, leading to excessive mobilization of body fat reserves and resulting …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 1–4 Read article
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Nigella Sativa Can Act as a Protective Agent to Fight Against Covid-19: An Update
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes Coronavirus Disease-19 (COVID-19), which began in Wuhan, Hubei Province, China and has since spread around the world. There are currently no effective antiviral medicines authorised for these coronavirus strains. Chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β, and other drugs are used to treat COVID19. There is no specific, effective, or proven conventional treatment to treat COVID-19 patients. As …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 13–18 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Comparative Evaluation of Autologous T-PRF Versus L-PRF Along with Freeze-dried Bone Allograft in the Management of Intra-bony Osseous Defect—A Report of Two Cases
Abstract: Periodontitis is a multifactorial inflammatory disease, characterized by formation of osseous deformities. Periodontal bone loss that presents with a vertical defect, is also known as an intra-bony defect. Different types of bone grafts may be employed to restore the compromised attachment structure. Freeze-dried bone allograft is a type of allograft which is osteoconductive in nature and acts as a scaffold. Platelet concentrates are biological products, filled with growth factors leading …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 2, 2023 · pp. 12–16 Read article
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A Study and Report on Due (Drug Utilization Evaluation) of Cardiovascular and Endocrine Disorders/Diseases in Inpatient Units of Hospitals
Abstract: In recent years drug utilization studies have become a potential tool to be used in the evaluation of health systems. On the process of drug utilization studies focus on factors related to prescribing, dispensing, administering, and taking of medication, and its associated events. Drug utilization data are available from databases- computerized or otherwise. From these databases different types of information, qualitative or quantitative or referring to a particular population are …
Published in Trends in Drug Delivery · Vol. 8, Issue 3, 2023 · pp. 11–32 Read article
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Radiological and Clinical Aspects of Nasal Septal Deformities in Chronic Rhinosinusitis Patients in Northern Indian Population
Abstract: The present paper aims to study the radiological and clinical aspects of septum deformities in chronic rhinosinusitis patients in Northern Indian Population. The classification of nasal septum deformities is another challenge in the management of septum deformities patients suffering from chronic rhinosinusitis (CRS). The present study shows that the septum deformities are very common in CRS patients. The Mladina classification is also discussed in the paper. Results show that types …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 1, 2016 · pp. 60–64 Read article
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Review on Cyperus scariosus: A Potential Medicinal Plant
Abstract: Saad kofi or Cyperus scariosus, known as Nagarmotha in India, is a delicate grass which is an angiosperm belonging to family Cyperaceae. Indian species of this plant is called motha. The best quality of saad is heavy in weight, rough from outside with strong aroma, whitish inside, highly bitter in taste. Its root extracts and volatile oil are used for medicinal purposes. Nagarmotha is also prescribed by local herbal medicine …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 4, 2021 · pp. 28–32 Read article
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Current Issues in Understanding of Diabetes
Abstract: Diabetes mellitus is a significant metabolic disorder that poses a major health concern, particularly in India. India harbours the world's highest number of diabetic patients, totalling around 130 million, with an additional 40 million categorised as prediabetic. In the global context, the number of adults suffering from diabetes was roughly 150 million in 2000, but this number is projected to significantly increase by 2030. The global prevalence of prediabetes is …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 2, 2023 · pp. 1–12 Read article
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Advances in Lung Cancer Detection and Diagnosis: An Integrative Approach Using Computational Chemistry, Statistics, Bioinformatics, Artificial Intelligence, and Machine Learning
Abstract: Lung cancer is still one of the most common and lethal cancers globally, accounting for more than a million deaths each year. Prompt detection is important, and imaging techniques like chest X-rays, MRIs, PETs, CTs, and molecular imaging have become important tools. But still, even though all these techniques do not provide an accurate classification of the lesion, they have led to the development of computer-based high-resolution image analysis. Computer …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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Al-Razi’s Anatomical Insights: A Detailed Review of Kitab Al-Mansuri
Abstract: Al-Razi (865–925 CE), a leading physician of the Greco-Arab Golden Age, made foundational contributions to human anatomy through clinical observation and empirical analysis. This review explores Al-Razi's anatomical insights, particularly as recorded in his influential medical compendium Kitab al-Mansuri (The Book of Medicine Dedicated to al-Mansur). In this work, Al-Razi challenges the prevailing Galenic doctrines by prioritizing evidence-based understanding over uncritical acceptance of ancient texts. His method reflects a scientific …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 1–7 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article