Search
299 articles for “Formulation Development”
-
Luminodeficit: The Paradox of High Rent and Abandoned Interiors
Abstract: The paradox of high rent and poor daylighting in residential buildings is a pressing issue in urban areas like Port Harcourt, Rivers State, Nigeria. Despite paying premium rents, many residents experience inadequate daylighting, leading to unexpected behavioral outcomes. This study aims to explore the effects of daylight deprivation on residents of high-rent residential buildings in Port Harcourt. It investigates how poor daylighting influences indoor time spent and overall occupant satisfaction, …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 1–7 Read article
-
Analyzing The Electromagnetic Transients and Corona Performance of Long Overhead Lines with Multiple Tower Spans
Abstract: This paper addresses the simulation of the electromagnetic transients developed in an important class of non-uniform high voltage power lines. The resulting information is of paramount importance for the proper planning, design, operation and protection of electric power networks. It deals particularly with long overhead high voltage transmission lines composed of several tower spans which are connected in cascade. The presented approach considers eventually existing localized corona discharges at some …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 1, 2025 · pp. 35–44 Read article
-
Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
-
Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review
Abstract: In this study, the vitamin D levels in fortified foods (including follow-on formula, baby porridge, and curd cheese dessert) and dietary supplements designed for infants were examined. Analytical assessments uncovered variations in vitamin D concentrations compared to the labeled values, fortified foods contain anywhere from 50% to 153% for supplements 8% to 177%. Instant follow-on formula and oil-based supplements typically aligned with or surpassed the labeled values, whereas ready-to-eat baby …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 19–24 Read article
-
Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article
-
Vedic Mathematics in Algebra Techniques, and Problem-Solving Benefits
Abstract: The sixteen Sutras and thirteen Sub-Sutras form the foundation of Vedic algebraic mathematics. This article discusses the Buddha's teachings and shows how to use them to solve algebra problems. Unified mathematics is defined as a state where processes can refer to and understand each other. Vedic formulas, which can be utilized for addition, subtraction, division, and other mathematical operations, are taught with examples. Vedic mathematics not only saves time, but …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 1, 2025 · pp. 23–28 Read article
-
A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
-
An Observational Study on Prevalence and Risk Factors for OA Knee Joint Among Adult Population Attending the SCSP Camps in Chennai, Tamil Nadu, India
Abstract: Background: Osteoarthritis (OA) is a prevalent degenerative condition affecting older individuals, particularly in developing nations. It is commonly linked to aging and various intricate underlying causes. The complex causes of osteoarthritis include confounding factors that significantly increase the risk of its development, many of which can be managed or prevented. Among all joints, knee osteoarthritis is particularly prevalent, especially in women. In rural India, the SC/ST population faces significant health …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 9–17 Read article
-
Analytical Method Development and Validation for Simultaneous Estimation of Paracetamol and Piroxicam by UV Method
Abstract: A new establishment and validation of a simple, precise, accurate and cost effective UV-Visible spectrophotometric method was developed to estimate both Paracetamol and Piroxicam simultaneously in conjoined pharmaceutical dosage forms. This technique was founded on simultaneous equation method of absorbances recorded at 252.0 nm and 282.0 nm of Paracetamol and Piroxicam in methanol respectively and an isosbestic point could be observed at 265.0 nm. It showed very good linearity over …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 14–21 Read article
-
RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
-
An Analytical study of Government Scheme for Farmers in Gujarat: Impact, Implementation Challenges, and Policy Implications
Abstract: Gujarat’s economy is mostly dependent on agriculture, which increases food security, rural employment, and state revenue. Despite the state’s notable progress in irrigation infrastructure and agricultural commercialization, Gujarat farmers continue to face challenges, such as market volatility, water scarcity, unpredictable weather, and rising input costs. The governments of Gujarat and India have implemented several initiatives aimed at addressing these problems, including crop insurance, irrigation expansion, farm mechanization, income support, digital …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 38–44 Read article
-
Effect of Span, Load Intensity, and Beam Geometry on Stress and Deflection Behavior of RCC Beams
Abstract: This study investigates the influence of variations in beam geometry, span, load intensity, and permissible stresses on the structural behavior of reinforced concrete beams. Using classical bending and shear stress formulations, the effects of a 20% increase in key parameters were analytically evaluated. Results indicate that a 20% increase in beam span leads to a proportional 20% increase in beam depth, whereas a 20% increase in beam width or permissible …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 9–22 Read article
-
Parametric Investigations of Melt Flow Index for Nylon6-Mica Composite Based Hybrid FDM Filament
Abstract: The development of new hybrid filaments with improved mechanical and thermal properties has been driven by the increasing need for high-performance materials in additive manufacturing. This study explores the parametric investigations of the Melt Flow Index (MFI) for Nylon6-Mica composite-based hybrid Fused Deposition Modeling (FDM) filament. The investigation uses the Taguchi technique to examine how different extrusion temperatures, loads and the percentage of Mica filler affect the MFI, a critical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 165–173 Read article
-
Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
-
In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
-
Pick and Place Drone using Primus X Flight Controller
Abstract: The development of an uncomplicated drone for pick-and-place tasks makes this project a superb beginner’s hands-on exercise. The drone is outfitted with an accelerometer, gyroscope, magnetometer, and barometric sensors which allows for controlled, stable flight. A Primus X flight controller powers the drone due to these features. The drone is sustained by a battery which drives four geared motor propellers. The gripper is designed in SolidWorks and cut using a …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 Read article
-
Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
-
A Traditional Indian Unani Dynamic Drug Amla (Emblica Officinalis) And Its Unani Pharmacological Activities In The Light of Recent Experimental Studies: A Comprehensive Review
Abstract: Since ancient times, plants have been essential to human development, serving as a primary source of natural remedies. The challenges associated with producing synthetic medications, along with their potential side effects and high costs, have driven researchers around the world to focus on the study of medicinal plants. In recent years, numerous publications have highlighted the role of plant-derived bioactive compounds in treating a wide range of human ailments, underscoring …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 21–29 Read article
-
Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article