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441 articles for “functionalization”
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Microbial Symphony: Understanding Biochemical Pathways for Precision Medicine and Beyond
Abstract: The human microbiome, an intricate ecosystem of microorganisms inhabiting the body, is a key regulator of host biochemistry and physiology. This review delves into the complex biochemical pathways influenced by the microbiome, spotlighting critical metabolites like short-chain fatty acids, bile acids, and tryptophan derivatives, which impact immune regulation, energy metabolism, and neurobehavioral functions. By examining interactions between the microbiome and the host, including the influence of genetic factors and metabolite-driven …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 28–43 Read article
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Exploring Muscle Energy Technique as A Physiotherapeutic Intervention for Peripheral Facial Palsy: A Pilot Report
Abstract: Background: Peripheral facial palsy results from damage to the peripheral branches of the facial nerve, often presenting as a sudden weakness in the muscles on one side of the face. Research on the application of muscle energy technique (MET) for treating this condition is scarce. Therefore, the aim of this study was to assess the effectiveness of MET in the treatment of peripheral facial palsy. Methods: 15 patients suffering from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 21–29 Read article
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Education and Skill Development for Sustainable Rural Development
Abstract: Leveraging education and skill development is a critical aspect of sustainable rural development enabling rural connected populations to gain knowledge and tools to enhance their economic opportunities, survive and thrive in changing environments and play its role in investment in rural development. This study analyzes the multiple functions of education and skill programs in rural areas, how they contribute to economic growth, social inclusion and environmental sustainability. Through focusing on …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 2, 2024 · pp. 10–20 Read article
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Emerging Trends in Drones across Multiple Sectors
Abstract: Drones, also known as unmanned aerial vehicles (UAVs), have become increasingly popular for their adaptability, affordability, and advanced functionalities. Originally developed for military purposes, they are now widely utilized across diverse sectors such as agriculture, filmmaking, and search and rescue missions. The impact of drones has been significant in various domains, such as reducing human casualties, providing more accurate information, increasing efficiency and cost reduction, and improving crop yields. Nonetheless, …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 2, Issue 2, 2024 · pp. 29–35 Read article
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Optimization of Production Processes to Minimize Waste and Improve Efficiency in Automobile Servicing Plant Using Lean Six Sigma
Abstract: This study focuses on optimizing production processes within an automobile servicing plant to minimize waste and enhance efficiency through the application of lean six sigma (LSS) methodologies. Utilizing a case study approach, the research addresses real-time challenges related to productivity and waste reduction. Data collection involves assessing machine functionality metrics, material and labor flow at various stages of the servicing process. The optimization strategy integrates lean tools including value stream …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 2, 2024 · pp. 47–63 Read article
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Under Voltage and Over Voltage Protection of Electrical Equipment - A Review
Abstract: In our modern, digitally-driven world, the seamless operation of electrical equipment is paramount, spanning industries, households, and infrastructure. However, the reliability of these vital assets is inextricably linked to the quality of electrical power supplied to them. Voltage fluctuations, specifically under voltage and over voltage events, pose significant threats to the integrity and functionality of electrical equipment. This review paper undertakes a comprehensive exploration of under voltage and over voltage …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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A Descriptive Study to Assess the Knowledge and Practices Among Staff Nurses Regarding Safe Urine Sample Collection in a Selected Hospital in Delhi, India
Abstract: Urine collection is a quick diagnostic test to assess kidney function. This study investigates the knowledge and practices of nurses regarding urine sample collection, a fundamental aspect of diagnostic procedures. Urine samples are critical for various tests, yet proper collection techniques are essential to ensure accuracy and prevent contamination. The study’s objectives were (a) To assess the level of knowledge among staff nurses regarding safe urine sample collection, and (b) …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Analysis of Losses in Geostationary Intersatellite Optical Wireless Communication Links
Abstract: The effective method to create a link between satellites is inter-satellite communication. Data is transmitted from one side to the other via a laser in this groundbreaking method. Optical networks, which offer continuous data transport over vast distances, are networks with high bandwidth efficiency. Inter-satellite optical wireless communication (Is-OWC) is a common method to transfer high-speed data between various satellites in free space. Is-OWC networks have undoubtedly innovated satellite communications …
Published in International Journal of Satellite Remote Sensing · Vol. 2, Issue 2, 2024 · pp. 1–18 Read article
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Arduino based Colour Sensing System with Real-time RGB Display on LCD
Abstract: Using a microcontroller Arduino UNO and TCS3200 color sensors, this project investigates the creation of a color measuring system. Colour sensors operate by emitting light onto an object and analyzing the reflected wavelengths to determine its colour. Our system is designed to detect a wide range of colours with high precision and display the corresponding Red-Green-Blue (RGB) values in real-time on a liquid crystal display (LCD). The TCS3200 sensor, developed …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 2, Issue 2, 2024 · pp. 35–43 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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An Investigation into the Efficacy of a Structured Teaching Program on Understanding Pubertal Changes and Menarche Among Adolescent Girls Enrolled at a Designated PU College in Gadag
Abstract: Background of the Study:Adolescence pertains to the phase of physical and physiological maturation occurring between childhood and adulthood. The commencement of adolescence, often linked to the initiation of puberty, introduces significant shifts in hormone levels and various ensuing physical transformations. The onset of puberty is also connected to substantial changes in drives, motivations, psychology, and social interactions, which persist throughout the adolescent period. A growing body of neuroimaging research is …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 20–39 Read article
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Aspergillus Oryzae: Multifunctional Powerhouse Revolutionizing Food Industries and Gut Health
Abstract: Aspergillus oryzae, commonly known as “Koji mold,” is a filamentous fungus extensively utilized in various food industries due to its robust enzymatic activity and generally recognized as safe (GRAS) status. This review explores its diverse applications, focusing on its role in fermented food production, enzyme generation, and contributions to gut health. In the production of fermented foods, such as soy sauce, miso, and sake, A. oryzae serves as a crucial …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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The Role of Education in Shaping Awareness and Attitudes Towards Politics
Abstract: Education provides individuals with a comprehensive understanding of the mechanisms of political systems, encompassing the functions of government, the intricacies of electoral processes, and the significance of political parties. The comprehension of the decision-making process is improved, and it demonstrates how people can actively influence those decisions. Education not only impacts people's political knowledge but also their attitudes toward politics and their sense of self as active citizens. In contrast …
Published in International Journal of Education Sciences · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Design for Wellness: Therapeutic Approaches in Workplace Interiors
Abstract: The modern workplace is increasingly recognized as a pivotal environment influencing employee well-being, productivity, and overall organizational success. This research paper delves into the integration of therapeutic design principles within office spaces to foster a healthier, more supportive environment for employees. The study investigates how strategic interior design can promote physical and mental well-being, reduce stress, and enhance employee satisfaction and productivity. By incorporating elements such as natural lighting, biophilic …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 2, 2024 · pp. 46–60 Read article
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Sustainable Materials for Contemporary Architecture: A Review
Abstract: The sustainability materials in the construction industry are crucial for fostering a more effective economy marked by reduced energy, waste, and pollution, lower emissions, improved safety of residents in public and residents through boosting interior air quality, increased job opportunities, and a more equitable wealth distribution. The objective of this study is to conduct an in-depth examination of sustainable construction materials by analyzing the challenges, barriers, prospects, motivations, and choices …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 2, 2024 · pp. 31–45 Read article
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Effects of Boko Haram Insurgency on Basic Education in the Southern Part of Borno State of Nigeria
Abstract: A place's level of educational development is determined by its society. The standard of education given determines a society's degree of political, economic, technological, religious, and cultural growth. The purpose of the study is to examine how the Boko Haram insurgency affects universal basic education (U.B.E.) in the southern region of Borno state, which is affected by the insurgency in many ways. The researchers want to consider the mayhem of …
Published in Recent Trends in Social Studies · Vol. 2, Issue 1, 2025 · pp. 34–47 Read article