Search
550 articles for “HIV-1 Integrase” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
Nothing matched all of your words, so these match any of them.
-
Assessment of the Impact of a Structured Educational Program on PCOS Knowledge Among Adolescent Girls in a Chosen Area of Tarn Taran District, Punjab
Abstract: Polycystic ovary syndrome (PCOS) is a health condition characterized by elevated levels of androgen hormones, irregular menstrual patterns, and the existence of small cysts on one or both ovaries. The disorder can be morphological or biochemical. Prevention of PCOS includes lifestyle modifications that are to manage weight, exercise, and dietary changes. Aim and Objectives: The main goal of this study was to assess the efficacy of a structured educational program …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 36–41 Read article
-
An AAV Vector for Inducible Gene Expression Preferentially in Muscles
Abstract: Adeno associated viral (AAV) vectors has been used widely in gene therapy and efforts have been made to improve their utility by adding genetic elements that would enable targeting transgene expression to particular cells or tissues of interest and permitting on/off regulation of expression. In this study, we designed a recombinant AAV9 variant PHP.eB vector with muscle creatine kinase (Mck)-derived enhancers, a synthetic muscle-expression promoter, in combination with a third-generation …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 46–61 Read article
-
Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
-
Prototype Model Development and Design Analysis of A Solar Tricycle for Physically Challenged People in India
Abstract: Society is greatly concerned about the mobility of individuals with physical disabilities. The scarcity of energy resources and the issue of pollution are currently the primary concerns. These issues can be resolved by employing alternative energy sources such as solar power. This paper presents an overview of the existing solar tricycles designed for those with disabilities. It also improves a handicapped-friendly solar-powered tricycle. The goal is to reduce handicapped people's …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 43–56 Read article
-
In vivo Modulatory Effect of Clerodendrum Splendens (Glory Blossom) in Aluminum Induced Alzheimer Diseases and Lonchocarpus Sericeus in Rotenone Induced Parkinson’s Disease on Na+/K+ Atpase (Sodium Pump) in the Cerebral Tissues of Male Albino Wister Rats
Abstract: Elegant research has shown that plants are useful for both curative and preventive purpose on the humans populous. Prevalent among diseases associated with humans are neurological diseases which affect a large sector of the population especially the elderly. The most common neurological diseases are Parkinson and Alzheimer disease which affect a large sector of the brain and also cause an imbalance in brain electrolyte. Among such electrolytic mechanisms of the …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 31–36 Read article
-
Assessing the Child–Parent Relationship Between Working and Non-working Mothers in a Selected Community of Bhubaneswar
Abstract: Introduction: Two categories of mothers exist: those who work outside the home, referred to as working mothers, and those who stay at home, often described as housewives. Working mothers may allocate quality time to their children, even if the amount of time is not necessarily large. On the other hand, non-working mothers not only manage household responsibilities but also provide care for their children and the entire family. Methods: A …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
-
Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
-
Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
-
The Influence of Fresh Raffia Palm Trunk on the Bioremediation of Oil-Based Drill
Abstract: This study determines the effect of fresh raffia palm for biodegradation of oil-based drill cuttings bioremediation. The experiment was conducted at the rivers institute of Agricultural research and training (RIART) located at the Rivers State University, Port Harcourt. Samples of oil-based drill cuttings were bulked in eleven reactors with four replications (T1, T2, T3-T11). The physiochemical properties of the initial drill cuttings were analyzed. Also, the physiochemical properties of the …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 2, 2023 · pp. 41–48 Read article
-
Pregnancy Outcomes on Chronically Hemodialyzed Women in Arab World: A Systematic Review
Abstract: Pregnancy carries a major risk of difficulties, as highlighted by the present systemic study on pregnancy outcomes in persistently hemodialyzed women in the Arab world. The objective of this systematic review was to describe the pregnancy outcomes among chronically hemodialyzed pregnant women in Arab countries in terms of the incidence of pregnancy among women on maintenance hemodialysis and the incidence of maternal and fetal complications of pregnant women on hemodialysis. …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 25–36 Read article
-
Coronary Vascular Disease: A General Review with Specific Reference to Etiology
Abstract: Cardiovascular disease (CVD), the foremost cause of mortality worldwide, has surged by 60% globally, reaching 20.5 million deaths in 2021 from 12.1 million in 1990, as per the latest report from the World Health Federation. While this increase is alarming on a global scale, it raises even greater concerns in countries like India where heart ailments are afflicting individuals at a younger age. The escalation of CVD among the younger …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
-
Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
-
Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review
Abstract: In this study, the vitamin D levels in fortified foods (including follow-on formula, baby porridge, and curd cheese dessert) and dietary supplements designed for infants were examined. Analytical assessments uncovered variations in vitamin D concentrations compared to the labeled values, fortified foods contain anywhere from 50% to 153% for supplements 8% to 177%. Instant follow-on formula and oil-based supplements typically aligned with or surpassed the labeled values, whereas ready-to-eat baby …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 19–24 Read article
-
Seasonal Variations of Air Quality Measures In Warri and Effurun, Delta State, Nigeria.
Abstract: Air quality in Urban Cities like Warri and Effurun has been deteriorating over time. The distribution levels of air pollutants in the Warri and Effurun environments may be related to both natural and man-made factors. In addition to evaluating the quality of rainwater with regard to pH, heavy metals (Fe, Pb, Cd, As, Hg, CU, Zn), and some anions (Cl-, NO3-, SO42-, CO32-), this project study aims to investigate, using …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 23–48 Read article
-
A study to assess the effect of nutritional supplementation on the hemoglobin level and the associated signs and symptoms of the students identified with anaemia in selected colleges of SNDT Womens’ University Mumbai
Abstract: The purpose of this study was to assess the effects of nutritional supplements on haemoglobin levels and related symptoms among students at SNDT Women's University in Mumbai who had been diagnosed with anaemia in a few particular institutions. Non-occurrence A sample of thirty anaemic students was selected via easy sampling. With a one-group pre-test-post-test methodology, the study used a descriptive evaluative design. Data collecting instruments included measurement devices, opinion questionnaires, …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 16–25 Read article
-
Stretching Boundaries: A Comprehensive Review of Ehlers-Danlos Syndrome and its Subtypes
Abstract: The Ehlers-Danlos syndromes (EDS) encompass 13 inheritable disorders affecting connective tissue. These conditions arise from genetic alterations impacting the structure of connective tissue. Every variant of Ehlers-Danlos syndrome (EDS) exhibits distinct features and has specific diagnostic criteria. While certain traits such as joint hypermobility, skin hyperextensibility, and tissue fragility are common across all types of EDS. The range of clinical presentations spans from minor skin and joint looseness to severe …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 44–57 Read article
-
Innovative Vaccine Technologies: Current Landscape and Future Prospects in Preventive Medicine
Abstract: This review article presents a comprehensive analysis of recent advancements and emerging trends in vaccine development, offering insights into the dynamic landscape of preventive medicine. Delving into a spectrum of infectious diseases, including influenza, HIV/AIDS, malaria, tuberculosis, respiratory syncytial virus (RSV), Group B Streptococcus (GBS), norovirus, and chikungunya, the review highlights innovative approaches and breakthroughs in vaccine technology. It explores efforts to develop universal influenza vaccines, long-awaited HIV vaccines, and …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 07–15 Read article
-
Biomedical Approach to Developing and Characterizing Chitosan Nanoparticles Encapsulating Urapidil for Hypertension Management
Abstract: The aim of this study was to create Chitosan Nanoparticles loaded with Urapidil to achieve controlled drug release, enhance solubility, and reduce dosing frequency to improve patient adherence to therapy for hypertension. Urapidil was formulated into nanoparticles via the ionic-gelation method using Chitosan as a polymer, Sodium tripolyphosphate as a cross-linking agent, and filled into hard gelatin capsules after lyophilization. Pre-formulation studies, including melting point analysis and determination of the …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 43–51 Read article
-
Gypsum Addition in Moulding Sand to Manufacture Defect Free Tin Castings
Abstract: Sand molding is a versatile casting process that provides freedom of design with respect to size, shape, and product quality. Plaster casting is similar to sand molding process except that a plaster is substituted instead of sand. Plaster compound is composed of gypsum, which strengthens the mould. Parts made by this process are gears, valves, fittings, tooling, and ornaments. The finished product of plaster casting has a very high surface …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 2, 2023 · pp. 7–15 Read article
-
Heat Treatment Research Studies of EN9 Carbon Steel by Quenching Operation in Different Quenching Media
Abstract: In this experimental research, EN9 type of steels is selected to process the heat treatment by quenching to increase the hardenability of a material. EN9 steel is cut into small work samples with diameter 25mm and length 15mm to analyze. Then they are polished the cut surface in a fine manner. Microstructure and hardness are to be found for EN9 work pieces before heat treatment at different locations like at …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 2, 2023 · pp. 1–25 Read article