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480 articles for “Drug Delivery”
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An Overview of Rheumatoid Arthritis: Enhancing Current Treatment Strategies Using Nanomaterials
Abstract: Background and Aim: Rheumatoid arthritis (RA) is a persistent and progressive autoimmune disease commonly affecting many people worldwide that severely attacks joints, leading to inflammation, cartilage destruction, and bone erosion. Exhaustive research on RA over the years has significantly contributed to a better understanding of the disease's causes, mechanism, progression, and treatment. Several therapies are available for its management, including anti-inflammatory and disease-modifying antirheumatic drugs. This present review aims at …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 25, Issue 1, 2023 · pp. 50–78 Read article
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A Review on Nano-emulsion for Delivery of Anti-cancer Drugs
Abstract: Cancer disease is characterized by abnormal cell growth. Malignant growth treatments have progressed significantly, yet there is a requirement for development in particularity and feeling of dread toward foundational harmfulness. Nanotechnology is the reconciliation of nanoscience into medication by the utilization of nanoparticles. The appearance of nanoscience in disease conclusion and treatment will assist clinicians with better surveying and oversee patients and further develop the medical care framework and administrations …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 7–13 Read article
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Polymeric Nanoparticles-A review
Abstract: Traditional use of medications is portrayed by helpless biodistribution, restricted adequacy and absence of selectivity. Systems like controlling medication conveyance can conceivably conquer these impediments by shipping medication to the spot of activity. The polymeric nanoparticles (PNPs) are set up from biocompatible and biodegradable polymers in size between 1-1000 nm where the medication is disintegrated, ensnared, epitomized or connected to a nanoparticle framework. PNPs are promising vehicles for drug conveyance …
Published in Trends in Drug Delivery · Vol. 7, Issue 3, 2020 · pp. 11–26 Read article
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Novel Nanotherapeutics for the Management of Diabetes
Abstract: Diabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and in case of Type …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 46–67 Read article
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Design and Evaluation of Thermo-Responsive Poly(N-isopropylacrylamide)-Based Polymeric Nanoparticles for Temperature-Triggered Intratumoral Release of Doxorubicin in Solid Tumors
Abstract: Thermo-responsive polymeric systems have emerged as promising platforms for targeted intratumoral drug delivery in cancer therapy. This study aimed to develop and evaluate poly(N-isopropylacrylamide) (PNIPAM)-based polymeric nanoparticles as intelligent carriers for temperature-responsive delivery of doxorubicin (DOX) to solid tumors. Nanoparticles were synthesized via free radical polymerization using N-isopropylacrylamide as a thermoresponsive monomer and N,N′-methylenebisacrylamide as a crosslinker, forming a stable network with a tunable lower critical solution temperature (LCST).The optimized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 159–168 Read article
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Solid Self Nanoemulsifying Tablets: Statistical Optimization by 23 Factorial Designs
Abstract: The objective of the current research was to enhance the solubility of poorly water soluble drug i.e. atorvastatin calcium, by self nanoemulsifying drug delivery system (SES) and formulating it as tablets using 23 factorial designs. The prepared liquid SES were adsorbed onto aerosil which acts as carrier. The 23 factorial designs were employed to optimize the concentration of micro-crystalline cellulose, PVP and sodium starch glycollate. The observed values were in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 2, 2017 · pp. 1–7 Read article
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A review on Advanced Materials for Sustainable Innovation and Innovative Applications in Chemical Engineering
Abstract: High level materials assume a vital part in driving feasible mechanical headways across different enterprises. This comprehensive review paper aims to provide an in-depth analysis of the properties, synthesis methods, and potential applications of advanced materials, focusing particularly on nanomaterials, biomaterials, and smart materials. These materials exhibit unique characteristics that render them indispensable for a wide array of applications, spanning energy storage, environmental remediation, healthcare, and electronics. Nanomaterials, characterized by …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 · pp. 59–79 Read article
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Design, Formulation, and Evaluation of Topical Meloxicam Emulgel
Abstract: AbstractThe study has the objective to formulate and evaluate meloxicam (MLX)-loaded nanoemulgel for topical drug delivery. Nanoemulsion is prepared by spontaneous emulsification technique. Nanoemulgel is prepared by adding nanoemulsion into the gel matrix. The characterization of meloxicam loaded nanoemulgel was performed. The formulations werecharacterized/evaluated for homogenicity, clarity, viscosity, pH, and drug release. In the present investigation, topical gel of MLX was formulated using pectin, polyethylene glycol (PEG), propylene glycol (PPG), …
Published in Trends in Drug Delivery · Vol. 9, Issue 3, 2022 · pp. 30–41 Read article
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In Vitro–In Vivo Correlation (IVIVC): A Strategic Tool in Drug Product Development
Abstract: In a recent era many concepts are dealing as an emerging tool for the drug delivery application like Biopharmaceutical Classification System (BCS), In vitro and In vivo study, and Bioavailability/Bioequivalence (BA/BE) study etc. To determine Therapeutic efficiency in vitro is not enough so the concept of In vitro-In vivo correlation (IVIVC) is playing as an convincing correlation with this for concept of pharmaceutical dosage forms have been a main focus …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 3, 2016 · pp. 31–54 Read article
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Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy
Abstract: This review provides an in-depth exploration of the evolution of ointment formulations, particularly considering the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges, such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift toward more advanced, innovative formulations that aim to address …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 14–23 Read article
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Fast Dissolving Oral Thin Films: A Review
Abstract: Fast-dissolving oral thin films (FDOFs) represent a significant advancement in drug delivery technology, offering advantages over traditional solid dosage forms, especially for patients with swallowing difficulties. FDOFs dissolve rapidly in the mouth, releasing the active ingredient without the need for water or chewing. They have picked up ubiquity due to their comfort, taste veiling capabilities, and progressed persistent compliance. Ideal drugs for FDOFs should possess characteristics such as solubility, stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 24–31 Read article
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Current Aspects of Nanomedicine for Cancer
Abstract: Nanotechnology is an advanced as well as budding branch of the science. It involves the studies of materials at the nano scale. It has demonstrated its enormous applications in almost every discipline like in biotechnology, medicines, electronics, etc. Among its nanotechnology, when applied to medical specialties than it is called nanomedicines. Nanomedicines are surprisingly effective in case of cancer. Nanomedicines provide better drug delivery as well as more efficacious against …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 1, 2014 · pp. 1–4 Read article
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A Concise Review on Microencapsulation
Abstract: Microencapsulation is novel technique to formulating containing micron sized particles of liquids, solids or gaseous in inert shell which protects from external coating material for the controlled drug delivery. Normally they contain the size of 1–1000 micron meter which used to physiological and pharmacokinetic factors to improve the more effectiveness for patient compliance. This review article will provide an overview of methods, morphology of microcapsule and application for encapsulation. Keywords: …
Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 1–6 Read article
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Cognitive Polymer Composite Systems for Autonomous Biomedical Response
Abstract: Cognitive polymer composite systems: A novel form of intelligent biomaterials with the capability to sense, process and respond to real time physiological stimuli on their own. The present paper offers a comprehensive platform to integrate stimulus responsive polymers with intrinsic sensing networks and learning based decision models to offer adaptable bio-medical solutions. Mathematical formulations are available that are used to model stimulus response behavior, sensor signal processing and cognition decision …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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A Comprehensive Study on Improving Contact Lens Performance Through Various Approaches
Abstract: Contact lenses improve vision quality by correcting refractive errors and thus provide a convenient alternative to traditional eyeglasses. Apart from vision enhancement, they have multiple applications in cosmetics, drug delivery, and therapeutic use. The performance of these lenses depends on various factors such as material, design, fitting, and interaction between the lens and the eye. The selection of appropriate materials is crucial for maintaining optimal eye health. Properties like oxygen …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 211–222 Read article
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Role of Nanotechnology in the Diagnosis and Treatment of Waterborne Diseases
Abstract: Nanotechnology provides new aspects for the treatment and diagnosis of diseases using atomic scale engineering of materials. The size of nanoparticles is similar to that of most biological molecules and structures; therefore, nanoparticles can be useful for both in vivo and in vitro biomedical research and applications. At the same time, the unique dimension of nanoparticles empowers them with special capabilities to successfully deliver the drug at the desired site. …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 4, Issue 1, 2014 · pp. 19–28 Read article
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Isolation and Characterization of Glucuronide Compound from Luffa Tuberosa (Roxb.) for Potential Applications in Polymer Chemistry
Abstract: This study explores the isolation process of glucuronide compounds from Luffa tuberosa (Roxb.) using an efficient and cost-effective method. The extracted compound, Gypsogenin-3β-O-β-D-Methyl glucuronide, is characterized using spectroscopic techniques such as IR, NMR, and Mass Spectrometry. The polymeric nature of glucuronide-based compounds and their potential applications in polymer and composite materials are discussed. The findings highlight the suitability of glucuronide derivatives in biomedical, pharmaceutical, and polymeric drug delivery systems. Additionally, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 566–572 Read article
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Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article
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Cubosomes: A Vanguard Wave of Nanotechnological Front
Abstract: Cubosomes are unique nano-sized drug delivery carriers that are formed by self-assembly of binary components i.e., aqueous lipids and surfactants. The most striking feature of cubosomes which make it indispensable is its controlled release profile. They are usually manufactured by high-energy dispersion aqueous lipid that is followed by thermodynamic and colloidal stabilization by using surfactants. After formation, the cubosomes is transformed into patient acceptable product and then administered it to …
Published in Trends in Drug Delivery · Vol. 5, Issue 2, 2018 · pp. 1–4 Read article
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Bioconjugates and Biohybrid Polymers: Intricate Cellular Integration Methods and Sophisticated Biofunctionalization Techniques for Tailored Properties in Medical Contexts
Abstract: Bioconjugates are made when biological molecules are covalently linked to manufactured polymers. They can be used in many ways for imaging, diagnosis, and specific drug delivery. Getting perfect cellular fusion is very important for how well they work. Biomolecules can be attached to polymer scaffolds in a controlled way using techniques like click chemistry and site-specific conjugation. This makes sure that the molecules connect optimally with their biological targets. Using …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 227–243 Read article