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1990 articles for “D’Alembert’s principle” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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An Approach for Managing Data in Cloud Using Resource Description Framework (RDF)
Abstract: Despite of late advances in appropriated Resource Description Framework information administration, handling a lot of RDF information in the cloud is still exceptionally difficult. Many of the original semi-structured data promises, such as flexible structure, optional schema, and rich, adaptable URIs as a basis for information sharing, are poised to be fulfilled by the W3C's Resource Description Framework (or RDF, for short). Furthermore, RDF is in a unique position to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 9, Issue 1, 2022 · pp. 1–10 Read article
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Power Quality Enhancement in Distribution System using D-STATCOM
Abstract: New solutions based on power electronics have been developed to safeguard commercial and industrial clients against power quality issues on the electrical distribution system, referred to as Custom Power Products. Custom power devices are classified into three categories by their structures such as dynamic voltage regulator (DVR), distribution static compensator (STATCOM) and unified power quality compensator (UPQC).The Distribution Static Compensator (D-STATCOM), one of the custom power product, is a shunt-connected …
Published in Recent Trends in Electronics Communication Systems · Vol. 8, Issue 2, 2021 · pp. 17–22 Read article
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Tadbeer-e-advia: A Unani Process of Detoxification of Poisonous Drugs: A Review
Abstract: The Unani System of Medicines (USM) is one of the oldest traditional systems of medicine, and deals with drugs of plants, animals and minerals origin where maximum are of plant origin. Most of the drugs used in USM are believed to be safe. But among the drugs of these origins are known for their toxic, undesirable and harmful effects. Unani Scholars divided all the drugs into four categories first, second, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2020 · pp. 1–5 Read article
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A Study to Develop and Test the Effectiveness of an Informational Booklet on Home Management of Patients with Bipolar Affective Disorder for the Family Members of Bipolar Affective Disorder Patients Receiving Treatment in Selected Hospitals of Delhi
Abstract: Mental health is still a neglected area in our society. The resentment, fear, shame, guilt are the common reactions faced by mentally ill people. Family has an important role when it comes to treating, rehabilitating, assisting an individual during illness. The aim of the study was to develop and test the effectiveness of an informational booklet on home management of patients with bipolar affective disorder for the family members of …
Published in Journal of Nursing Science & Practice · Vol. 4, Issue 2, 2014 · pp. 9–18 Read article
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Presentation Delay in Breast Cancer Patients, Identifying the Barriers Among Women Receiving Breast Cancer Drugs at Hawassa University Comprehensive and Specialized Hospital, Ethiopia
Abstract: Background: Breast cancer remains the most common cancer and most common cause of cancer-related mortality among women worldwide [1]. While incidence rates have historically been higher in the developed world, there has been a recent sharp increase in incidence and mortality in the developing world [2]. Objectives: The main purpose of this study was to assess the barriers resulting in delayed patient presentation to breast cancer care among women receiving …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 3, 2018 · pp. 24–31 Read article
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Clinical Profile of Dengue Fever with Its Acute Complications in Rural Population of Jaipur District
Abstract: Dengue is the most important mosquito-borne viral infection in terms of morbidity and mortality. In recent years, it has become a major public health concern. The present study was conducted on hospitalized adult patients of NIMS Medical College & Hospital with the aim to study the clinical profile and usual presentations of dengue fever. During the study of 75 patients of dengue infection, 18 had dengue fever (DF), 19 had …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 12–23 Read article
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Effect of Co-empowering Both Mother and Mother-in-Law on the Prenatal, Delivery, Postnatal Knowledge and Practices in the Far West Region of Nepal
Abstract: This study compares prenatal, delivery, and postnatal knowledge and practices of daughter-in-law/mother-in-law (DIL/MIL) pairs who participated in an intervention meeting with those DIL/MIL pairs compared to where only DIL participated in the Female Community Health Volunteer (FCHV) meeting in Kailali district, far-west region of Nepal. The intervention was a 1−2 h meeting before the delivery with the DIL/MIL and the FCHV. The topics covered during the meeting were based on …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 3, Issue 3, 2014 · pp. 1–12 Read article
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Adverse Events Associated with Oral First-in-Man Administration of New Chemical Entities Compared with Placebo – An Analysis of 14 Single- and Multi-Dosing, Double-Blind, Placebo-Controlled Studies
Abstract: This investigation is a retrospective analysis of the adverse events (AEs) associated with oral administration of new chemical entities (NCEs)for the first time in humans. We gathered data from 14 single- and multiple-dosings of FIM NCE studies conducted in our centre over a period of 5 years. In total, 452 subjects were dosed. A total of 2280 doses were administered. Active medication was given on 1763 dosing occasions and placebo …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 3, 2012 · pp. 1–6 Read article
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Digital Therapeutics for Management of Chronic Diseases
Abstract: Digital therapeutics (DTx) mark a major advancement in modern medicine, using advanced software technologies to deliver clinically validated treatments for various physical and mental health conditions. Unlike general wellness apps that focus on fitness or lifestyle tracking, DTx are evidence-based medical interventions developed through rigorous clinical research to ensure safety, efficacy, and measurable outcomes. Delivered via digital platforms such as smartphones, tablets, or specialized medical devices, DTx aim to prevent, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Necessity of “Cigarette Smoking De-Addiction Kiosks” at Ayush Health and Wellness Centers – An Overview
Abstract: Introduction and Socio-Demography: Cigarette is the most common form of smoked tobacco that is used globally. About 1.3 million deaths have been reported in India associated with tobacco use. India has implemented several tobacco controls measures, and as a part of that, de-addiction centers play an important role in treating addictions using various therapies. However, the discontinuation from taking de-addiction care from those allopathic centers is high due to higher …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 9–19 Read article
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Density Functional Theory (DFT): Understanding and Quantifying Molecular Structure of 2-D Materials
Abstract: Density Functional Theory (DFT) has emerged as a cornerstone in computational chemistry and materials science, offering a powerful framework for predicting electronic structures and properties of atoms, molecules, and solids. By focusing on electron density rather than wave functions, DFT simplifies the many-body problem through approximations like the local density approximation (LDA) and generalized-gradient approximations (GGAs). The Hohenberg-Kohn theorems establish the theoretical foundation, proving that ground-state properties are uniquely determined …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 2, 2025 · pp. 33–40 Read article
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A Comprehensive Review of CNN-Based Framework for Multi-Sign Detection of Diabetic Retinopathy in Fundus Images Using Public Datasets
Abstract: Diabetic retinopathy (DR) is one of the main causes of vision impairment. Blindness prevention and effective treatment depend on early detection. A thorough deep learning-based framework for the automatic segmentation and simultaneous detection of exudates, hemorrhages, and microaneurysms – three important DR indicators – from retinal fundus images is presented in this work. These three pathological signs’ corresponding annotated image patches, along with background (no-sign) areas, were used to train …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 14–23 Read article
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Development and Optimization of Orally Disintegrating Tablets (ODTs) Containing Standardized Curcumin Extract for Enhanced Bioavailability and Patient Compliance
Abstract: This research centers on creating and perfecting orally disintegrating tablets with standardized curcumin extract to both increase its bioavailability and promote better patient adherence. Although curcumin has numerous therapeutic applications. It remains clinically ineffective due to its poor aqueous solubility and bioavailability constraints. The development of orally disintegrating tablets involved direct compression with various levels of superdisintegrants including sodium starch glycolate and cross povidone to address existing challenges. Research teams …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 1–06 Read article