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1908 articles for “beclin-1” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Current Perspectives of Prader -Willi Syndrome: A Multisystem Approach
Abstract: Prader-Willi syndrome (PWS) is a genetic disorder with multisystem involvement, caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region from paternal 15q11-q13 deletions (about 60%) or maternal uniparental disomy 15 or both. It is a complex and contiguous gene disorder which affects the multiple systems with many clinical presentations especially hypothalamic insufficiency. The clinical features are characterized by short stature position, developmental delay, cognitive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 42–48 Read article
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Effects of the Embryonic Bisphenol an Exposure on The Postnatal Development, Learning and Memory of Rat Offspring: Fundamental Study
Abstract: We studied the morphologic changes in some organs and changes of learning and memory of the rat offspring after the embryonic bisphenol A exposure. Background: Bisphenol A, widely used as polycarbonate plastics material to manufacture food packaging, toys, glasses, computers, kitchen utensils and medical instruments, is one of the most common endocrine-disrupting chemicals. It is demonstrated that bisphenol A may be mingled with foodstuff and beverage from package and receptacle. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 58–63 Read article
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A Study On Improving The Performance Of Concrete Using Coconut Fibers
Abstract: The aim of this study is to explore the incorporation of coconut fiber into M30 grade concrete and assess its impact on the strength characteristics. A literature review of different fibers is conducted and highlighting the working parameters. This research focuses to explore the efficacy of employing coconut fibers as micro reinforcement in concrete. The investigated properties encompass the compressive strength of the coconut fibers reinforced concrete (CFRC) at different …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 26–36 Read article
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IUCN Conservation Status and Global Population Trends of Avifauna in Pong Dam Lake Wildlife Sanctuary, Himachal Pradesh
Abstract: The expansive wetland at Pong Dam Lake, which is located within the picturesque Kangra district of Himachal Pradesh, stands out prominently as one of the largest artificially created wetlands in the entire region. This wetland is renowned for its biodiversity, particularly its avian population. In a comprehensive survey an impressive total of 225 bird species residing within the Pong Dam Lake Wildlife Sanctuary were documented. These species are spread across …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 3, 2024 · pp. 13–23 Read article
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A Comparative Analysis of Factors Contributing to Relapse in Alcohol and Opioid Dependence Among Patients Admitted to Selected Hospitals in Ludhiana, Punjab.
Abstract: Introduction: Substance abuse involves the dangerous or detrimental use of psychoactive substances, such as alcohol and illegal drugs. The use of these substances can result in dependence syndrome, which encompasses a range of behavioral, cognitive, and physiological effects that arise from ongoing substance use. Objectives: This study was carried out to examine the factors linked to relapse in alcohol and opioid dependence among patients admitted to selected hospitals in Ludhiana, …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Investigating the Occurrence and Damage of Wild Pig (Sus scrofa) in Cassava Ecosystems of Kerala
Abstract: The study investigates the occurrence and impact of wild pigs on cassava crops in selected locations of Thrissur and Palakkad districts of Kerala, spanning from July 2022 to May 2023. Data were collected from 10 sites, where each 1-acre field was divided into 5 quadrants for monitoring. The presence of wild pigs was tracked weekly through pug marks, infrared cameras, and farmer reports, while the extent of cassava plant damage …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 16–20 Read article
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Foundation in Weak Soil
Abstract: In geotechnical engineering, it is crucial to evaluate the interaction between structural loads and soil properties to ensure the stability and safety of foundations. In this scenario, the column is subjected to a load of 120 tons, with an additional 10% safety factor added, resulting in a total load of 132 tons at the foundation base. The foundation base is designed with dimensions of 2.5 meters by 2.5 meters, and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 47–52 Read article
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Assessing Supportive Care Needs Among Breast Cancer Survivors: A Cross-Sectional Study
Abstract: Breast cancer poses a significant global health challenge and ranks among the primary causes of cancer-related morbidity and mortality worldwide. The objective of this study was to evaluate the supportive care needs of survivors of breast cancer and examine how these needs are related to various background factors. To accomplish this, a cross-sectional study was carried out with 116 breast cancer survivors, selected using a convenient sampling method. Data were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 39–42 Read article
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Exploring Muscle Energy Technique as A Physiotherapeutic Intervention for Peripheral Facial Palsy: A Pilot Report
Abstract: Background: Peripheral facial palsy results from damage to the peripheral branches of the facial nerve, often presenting as a sudden weakness in the muscles on one side of the face. Research on the application of muscle energy technique (MET) for treating this condition is scarce. Therefore, the aim of this study was to assess the effectiveness of MET in the treatment of peripheral facial palsy. Methods: 15 patients suffering from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 21–29 Read article
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Diversity and Abundance of Fish Species in Lower River Benue, Makurdi, Nigeria
Abstract: This study evaluated the diversity and abundance of fish species in Lower River Benue, Makurdi, Nigeria, for a duration of 3 months. Fish samples were collected from fishermen at immediately after landing using assorted fish gears. A total of 1, 106 fish specimens, representing 16 families and 35 species, were identified and examined. The dominant families from the sample were Cichlidae (24%) and Schilbeidae (20%) while the families Distochontidae, Latidae, …
Published in Research & Reviews : Journal of Ecology · Vol. 14, Issue 1, 2025 · pp. 18–25 Read article
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Study of Groundwater Quality in Shallow Tubewells of Bhubaneswar City Using WQI Method
Abstract: Shallow groundwater is extremely vulnerable owing to overexploitation, anthropogenic activities, and environmental effects. Declining quality of groundwater poses an enormous risk for human health and the entire ecosystem. Nearly 50 per cent urban water supply is contributed by groundwater in Indian cities. Since Bhubaneswar shares a similar scenario where 34 out of 67 wards are partially covered with municipal water supply and the residents of these areas are largely dependent …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 559–574 Read article
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Evaluating the Role of Apple Cider Vinegar in Managing Semaglutide-Induced Gastrointestinal Disturbances: A Systematic Review
Abstract: Background: Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is highly effective in treating type 2 diabetes and obesity. However, its use is often associated with gastrointestinal side effects, including nausea, vomiting, and diarrhea, which may impact patient compliance. Objective: This systematic review aims to evaluate the evidence regarding the management of semaglutide-induced GI symptoms and assess the potential role of apple cider vinegar (ACV) as a complementary treatment. Methods: A …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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Assay of the Antitrypanosomal Activity of Ziingiber Officinale Extract in Wister Rats
Abstract: This research investigated the antitrypanosomal effects of Zingiber officinale in rats infected with Trypanosoma brucei brucei. Twelve adult rats, 7 weeks old and of both sexes, were randomly divided into six groups (1 through 6), with each group consisting of two rats. All six groups (1–6) were intraperitoneally injected with 0.1 ml of blood containing 10⁶ Trypanosomes/ml. Groups 1–4 received daily intraperitoneal doses of the plant extract at concentrations of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 32–37 Read article
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Bibliometric Analysis of TNAI’s The Nursing Journal of India, 2014-2023
Abstract: Since 1910, the Nursing Journal of India of TNAI has been playing a vital role in scattering of information and knowledge in various aspects of nursing and allied health care. This bibliometric (statistical) analysis is based on only 443 citing articles in English languages which are published in this Journal in 10 volumes (2014-2023). Out of total, 442 papers are under personal and one under corporate authorship. This study shows …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 2, 2024 · pp. 1–17 Read article
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Au@Sio2@PVP-DCMD Membranes: A Breakthrough in Heavy Metal Removal and Antibacterial Defense
Abstract: This study investigates the development and characterization of multifunctional gold-doped silica (Au@SiO₂) membranes for water distillation and antibacterial applications. The manufacturing process integrated gold nanoparticles into silica matrices using sol-gel techniques. Structural analysis was conducted using SEM (showing uniform pore distribution with an average pore size of 40-50 nm), FTIR (confirming Si-O-Si and Si-Au-Si bonding peaks at 525 cm⁻¹ and 1310 cm⁻¹ respectively), EDX (revealing gold nanoparticle content of 1.5 …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 13–27 Read article
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Mix Proportioning of Biochar as a Partial Replacement of Cement Using Alkaline Activators in Concrete Composite
Abstract: The growth of the world population has led to a heightened need for housing, making construction a crucial sector. Cement, a critical element in concrete mixtures, is indispensable in construction activities. Yet, the diminishing reserves of natural resources such as limestone and rocks, essential for cement manufacturing, necessitate sustainable options. This research investigates the creation of sustainable concrete blends by incorporating biochar and ground granulated blast furnace slag (GGBS), activated …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 628–639 Read article
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Enhancing Thermal and Mechanical Performance of Polymer-Based Phase Change Materials with Graphite Nanoplatelets: A High-Efficiency Approach for Energy Storage Applications
Abstract: This study explores the performance enhancement and characterization of polymer-based phase change material (PCM) composites reinforced with graphite nanoplatelets (GNPs) for thermal management applications. The integration of GNPs significantly improved thermal conductivity, which increased from 0.38 W/m·K in pure PCM to 2.60 W/m·K with 10 wt% GNPs, marking a 580% improvement. Differential Scanning Calorimetry (DSC) analysis revealed a reduction in latent heat capacity from 180 J/g to 150 J/g—approximately 16.7%—attributed …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 150–162 Read article
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An Evaluation of the Impact of a Nurse-Led Program on Knowledge and Practices Related to Needle Stick Injury Prevention Among 2nd Year B.Sc. Nursing Students at the College of Nursing, PT. B.D. Sharma PGIMS, Rohtak
Abstract: Healthcare workers and nursing students frequently face accidental occupational exposures while caring for patients, with needle stick injuries being the most common form of exposure in healthcare settings. These injuries pose a significant risk of infections. This study aimed to evaluate the awareness and practices related to the prevention of needle stick injuries among second-year B.Sc. Nursing students, assess the effectiveness of a nurse-led intervention in enhancing their knowledge and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 28–66 Read article
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Acalypha Indica Root Fibre in Polymer Composite: Mechanical Characterization
Abstract: The mechanical characteristics of Acalypha Indica root fibre reinforced epoxy resin composites, including tensile strength, tensile modulus, percentage of elongation, flexural strength, and impact strength, were studied. Composites were fabricated using epoxy glue and randomly oriented fibres of 3 mm length in varying weight ratios of 10%, 20%, 30%, and 40%. The hand layup method was followed by compression moulding to construct the composites. The study aimed to determine the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 512–522 Read article