Search
258 articles for “Infection Diseases”
-
A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
-
ArcGIS Applications in COVID-19 Spatial Epidemiology: A Comprehensive Systematic Review
Abstract: Addressing complicated community health concerns frequently necessitates the establishment of health practices. Professionals who study community health using information technology require a thorough framework. Health care professionals and authorities have had the ability to comprehend health-related geographical data and make timely judgments in different situations. In the field of epidemic disease prevention, including a viral spread model into a GIS is a popular issue. As a result, a GIS as …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 2, 2025 · pp. 17–25 Read article
-
A Novel Solution to Oral Hygiene
Abstract: This paper proposes a novel approach to oral health monitoring through the development of a smart toothbrush equipped with a camera, pH sensor, and temperature sensor. The integration of these sensors allows for real-time monitoring and early detection of potential oral health issues such as cavities, gum disease, pyorrhea and enamel erosion. The camera provides visual data for assessing plaque buildup and other visible signs of oral health problems, while …
Published in Journal of Microwave Engineering and Technologies · Vol. 11, Issue 2, 2024 · pp. 29–34 Read article
-
Progression in multi-omics and immunological research on host-parasite interactions: Transcriptomics, proteomics, genomics, metabolomics, and immune responses
Abstract: The interaction occuring between hosts and parasites is a quick and multi step-complex biological process that tries to influence disease outcomes. In recent years, multi-omics approaches, such as transcriptomics, proteomics, genomics, metabolomics, and immunological studies, have gathered substantial eye in dissecting these interactions at a microscopic level. These techniques enable a vast understanding of the molecular structures involved in parasitic infections and host defense mechanisms. This article reviews the advancements …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
-
Scientometric Insights and Meta-Analysis of Japanese Encephalitis Research in India
Abstract: Japanese Encephalitis (JE) represents India’s critical public health issue, contributing significantly to regional morbidity and mortality. This study details the findings from a scientometric analysis of JE research conducted in India. Our study analyzed scientific publications to uncover trends, key contributors, gaps, and the thematic evolution within JE research, providing insights critical for shaping future research and policy directions. A comprehensive scientometric analysis of research on JE published in India …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 43–53 Read article
-
Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
-
Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article
-
Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
-
Modeling the Novel Coronavirus Disease (COVID-19) as Hidden Markov Chains
Abstract: The Hidden Markov Model has over the years been an appropriate method for modeling diseases such as HIV AIDS, heart failure, and so on. With the ongoing pandemic affecting Nigeria by being responsible for 2,745 death cases out of 207,616 confirmed cases as of October 10, 2021, the need to study an important parameter of COVID-19, the case fatality rate by building a model and estimating the case fatality rate …
Published in Research & Reviews : Journal of Statistics Read article
-
Shadows of Uncertainty: When Pneumonia Isn’t Pneumonia
Abstract: Pneumonia is a common medical condition encountered in hospitalized patients and remains a cause of morbidity worldwide. Identifying and initiating appropriate treatment in febrile patients who present with respiratory symptoms and radiographic infiltrates, reduce hospital stay, minimize complications, and lower healthcare costs. However, the assumption that every pulmonary infiltrate or opacity seen on a radiological imaging represents an infectious process such as pneumonia can lead to misdiagnosis, unnecessary investigations, prolonged …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 24–29 Read article
-
Cervical Cancer: Understanding Its Causes, Risk Factors, and Preventive Measures
Abstract: Cervical cancer is a form of cancer that begins in the cervix, the lower portion of the uterus, due to abnormal cell growth that can spread or invade other areas of the body. In its early stages, cervical cancer usually shows no obvious symptoms, which is why regular screenings are essential for detecting it early. As the cancer advances, symptoms such as pelvic pain, unusual vaginal bleeding, and pain during …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 26–30 Read article
-
Japanese Encephalitis and Dengue Fever Co-infection
Abstract: Dengue virus (DENV) and Japanese encephalitis virus (JEV) are two significant pathogenic viruses that can cause severe encephalitis. Dengue and Japanese encephalitis are vector-borne illnesses.Arboviruses that are carried by mosquitoes are significant India's causes of death and morbidity The rainy season, when the vector population grows, is when both dengue and Japanese encephalitis transmissions peak. We still don't fully understand how the CNS is involved in dengue and Japanese encephalitis …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
-
The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
-
An Ayurveda Management of High Level of Fecal Calprotectin – A Single Case Study
Abstract: Calprotectin is protein found in leucocytes. Calprotectin plays a crucial role in various physiological processes, including cell differentiation, immune modulation, tumor development, programmed cell death, and inflammatory responses. Gut inflammation due to various cause like genetic inheritance, changes in microbiota within intestine, defective immune regulation. Also, some infective such as salmonella, E. coli, Cytomegalovirus, Amoebiasis etc., and Non-infective such as Ischaemic colitis, Non-steroidal anti-inflammatory drugs, Colonic carcinoma etc., can mimic …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 3, 2024 · pp. 19–25 Read article
-
A Comprehensive Review on COVID-19 Evolution and Development
Abstract: The emerging pandemic causing flu-like symptoms in patients is caused by the novel Coronavirus that was previously called 2019-nCoV. The mutated gene of SARS-CoV was transformed to SARS-CoV-2 in animals and further transmitted to humans in the month of December 2019 in Wuhan city of China. Eventually, the novel coronavirus spread all around the globe as a highly contagious disease. COVID-19 (the illness caused by coronavirus) has affected 213 countries …
Published in Research and Reviews : A Journal of Life Sciences Read article
-
Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
-
Nutritional Influence on Gut Health and Immune Function: An Integrative Perspective
Abstract: The study of nutrition, gut health, and immune function is fast changing and has major implications for disease prevention and management. A varied microbiome in the gut regulates immune responses. A balanced diet with fiber, polyphenols, and important nutrients maintains a healthy gut flora, which regulates immune function and inflammation. Dysbiosis, an imbalance in the gut microbiota, is connected to autoimmune, allergic, and inflammatory bowel illnesses. New research reveals that …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 30–44 Read article
-
Review of Punravartak Jwara with Relationship to Recent Surge in Cardiac Death and COVID-19 Infection
Abstract: The unprecedented 12.5% surge of sudden cardiac death has been reported after COVID-19 outbreak. Central health agency has opined that the COVID-19 vaccine has no relationship with this surge; but the sudden cardiac death with shift i.e. the sudden cardiac death of young in their 40 even with cases of sudden cardiac death in the age group of 20–40. This paradigm change in the prevalence is of serious concern as …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 27–31 Read article
-
Bone Grafting in Dentistry: From Biological Principles to Contemporary Regenerative Applications
Abstract: Bone grafting plays a pivotal role in contemporary regenerative dentistry by enabling predictable reconstruction of alveolar bone defects resulting from periodontal disease, tooth extraction, trauma, or pathology. Adequate bone volume and quality are essential prerequisites for successful implant placement, periodontal regeneration, and long-term functional and esthetic outcomes. Bone graft materials act as biological or synthetic scaffolds that facilitate new bone formation through the primary mechanisms of osteogenesis, osteoinduction, osteoconduction, and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 6–13 Read article
-
Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article