Search
319 articles for “Drug delivery systems”
-
Advanced Functional Polymers and Their Synergistic Role in Smart Composite Materials for Sustainable Industrial Applications
Abstract: Advanced functional polymers have revolutionized composite materials, offering enhanced properties such as self-healing, electrical conductivity, environmental adaptability, and high mechanical strength. These innovations are reshaping industries by enabling smarter, more efficient, and sustainable solutions. Functional polymers play a pivotal role in producing high-performance composite materials to meet the growing demands of sustainable industrial applications. Significant improvements in material properties mechanical strength, durability, thermal stability, and recyclability are achieved through the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 12–27 Read article
-
Preparation and Characterization of Eucalyptus Oil Nasal Microemulsion System Using Polysorbate 80
Abstract: The nasal route is considered as an alternative route of drug administration for the delivery and targeting drugs safely. The nasal absorption of the drug protects from the degradation of the drug in the gastrointestinal environment and liver metabolism. Eucalyptus oil is an essential oil frequently used for the treatment of common cold and nasal congestion. The microemulsion system of eucalyptus oil will provide effective delivery of the oil to …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
-
Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 50–64 Read article
-
Development and Characterization of 5-Fluorouracil Cubosomal Nanosponge Tablet for Colon Targeting
Abstract: The objective of this study was to develop nano-scale delivery system to improve nanometric size range, percentage drug entrapment efficiency, controlled release of the incorporated drug and the protection against degradation. 5-FU loaded cubosomal dispersion was prepared by the bottom up technique and formulation was characterized. From this, 5-FU cubosomal nanosponges were prepared by the emulsion solvent diffusion method using various pH dependent polymers and evaluated, encapsulation of this formulation …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 9–18 Read article
-
A Futuristic concept of understanding Biosimilars in the Pharmaceutical Field
Abstract: Biosimilars, which are highly similar versions of approved biologic drugs, are expected to continue their expansion into new therapeutic areas, offering cost-effective alternatives to a wider range of medical conditions. This evolution includes the development of next-generation biosimilars with improved properties, such as enhanced efficacy, safety, and patient convenience. Innovations in drug delivery methods, reduced immunogenicity, and personalized medicine are anticipated to drive the development of biosimilars tailored to individual …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 3, 2023 · pp. 10–20 Read article
-
Design and Evaluation of Thermo-Responsive Poly(N-isopropylacrylamide)-Based Polymeric Nanoparticles for Temperature-Triggered Intratumoral Release of Doxorubicin in Solid Tumors
Abstract: Thermo-responsive polymeric systems have emerged as promising platforms for targeted intratumoral drug delivery in cancer therapy. This study aimed to develop and evaluate poly(N-isopropylacrylamide) (PNIPAM)-based polymeric nanoparticles as intelligent carriers for temperature-responsive delivery of doxorubicin (DOX) to solid tumors. Nanoparticles were synthesized via free radical polymerization using N-isopropylacrylamide as a thermoresponsive monomer and N,N′-methylenebisacrylamide as a crosslinker, forming a stable network with a tunable lower critical solution temperature (LCST).The optimized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 159–168 Read article
-
Initiatives of Nanotechnology to Combat Diabetes Mellitus
Abstract: Diabetes is the single most important metabolic disease which can affect approximately every organ system in the body. It has been projected that 300 million individuals would be affected with diabetes by the year 2025. In India, it is estimated that presently 19.4 million individuals are affected by this deadly disease, which is likely to go up to 57.2 million by the year 2025. It is imperative that effective monitoring …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 2, 2013 · pp. 38–47 Read article
-
Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
-
Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
-
Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
-
The Utilization of Oil Entrapped Floating Alginate Beads in a Gastroretentive Delivery System is Intended to Improve the Bioavailbility of Telmisartan Incorporating Principles of Bioinformatics
Abstract: Oil entrapped floating calcium alginate beads of Telmisartan were successfully prepared using sodium alginate as polymer and two different oil phases of mineral oil and olive oil by emulsion gelation method. The FT-IR spectra of final optimized formulation confirms no drug- polymer incompatibility. The floating time of beads was found to be more than 12 hrs suggesting that the method used for prepration was effective. The floating time of optimized …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 21–38 Read article
-
Integration of Raspberry Pi and Arduino for an Intelligent Medicine Dispensing System in Healthcare Facilities
Abstract: "Automatic Medicine Dispenser Using QR Code" revolutionizes healthcare service delivery by minimizing queue-related inconveniences. Our project created a vending machine using QR code technology in response to the evolving healthcare and technological landscape. The system is powered by an Arduino Mega 2560 and includes key components like a DC gear motor, L298N motor driver, infrared sensor, HC05 Bluetooth module, and a 12V power supply for drug delivery. The project comprises …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 2, 2024 · pp. 33–45 Read article
-
The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
-
Microsponges: A Novel Approach for Transdermal Delivery of Tolnaftate
Abstract: The present study was aimed at preparing tolnaftate-loaded microsponges and incorporating them into a topical formulation. Microsponge delivery system was chosen as it can increase the concentration of the drug on the superficial layer of the skin. Microsponges were prepared by quasi-emulsion technique. The studies like drug entrapment efficiency showed that the drug was completely entrapped within the pores of the microsponges. The microsponges were incorporated into the optimized carbopol …
Published in Trends in Drug Delivery · Vol. 2, Issue 2, 2015 · pp. 38–46 Read article
-
Supergenerics Regulation in India and US: A Comparative Review
Abstract: ‘Supergenerics’, a new form of generic drugs with improved properties such as safety, efficacy, stability or improved commercial attractiveness such as taste or route of administration. Those drugs are most often based on an incremental re-formulation of a generic API (active pharmaceutical ingredient) or the combination of multiple generic APIs. Process of forming supergeneric molecule need not to be complex all the time. A supergeneric may be as simple as …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 1, 2016 · pp. 30–38 Read article
-
Polymer Chemistry and Nanocomposite Network Design of PEGDA-Based Hydrogels
Abstract: The chemical structure and crosslinking density of polyethylene glycol diacrylate (PEGDA) can be systematically tailored, making it a versatile polymeric network in biomedical engineering, drug delivery, tissue engineering, biosensing and advanced manufacturing. PEGDA is a polymerizable acrylate-functionalized hydrophilic PEG that can be polymerized to make three-dimensional networks via free-radical polymerization, specifically photoinitiated. The resulting network architecture depends on the PEGDA molecular weight, the concentration of precursors, the polymerization conditions, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
-
Development and Characterization of Bifonazole Nitrate Nanosuspension Loaded Topical Gel
Abstract: Objective: The goal of the present study was to formulate and evaluate nanosuspension-based topical delivery system of bifonazole nitrate (BN) or increased saturation solubility and controlled drug release. Methods: BN nanosuspension was prepared by pearl milling technique using zirconium oxide beads as a milling media, poloxamer 407 as a stabilizer and glycerol as wetting agent. Effect of various process parameters such as, stirring time and poloxamer concentration were optimized. The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 9, Issue 2, 2018 · pp. 36–48 Read article
-
Exploring Carbon Nanotubes in Nanotechnology: Functional Properties, Surface Modifications, and Biomedical Innovations
Abstract: Significant progress has been made in nanotechnology in recent years, especially in the creation of sensors with a broad range of uses. Among these, carbon nanotubes (CNTs) are cylindrical structures composed of carbon, with diameters in the nanometer range. CNTs originate from graphite sheets, where the graphite layers resemble a rolled-up, continuous, and robust hexagonal mesh. These hexagons have carbon atoms at their vertices. The fabrication of CNTs typically involves …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 24–31 Read article
-
Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
-
The Role of Artificial Intelligence and Machine Learning in Redefining Global Healthcare Systems and Advancing Medical Innovation
Abstract: Health Services are being revolutionized with AI and ML through improved accuracy, efficiency and accessibility in the delivery of health care. With AI and ML, it is now possible for health care professionals to assess varying amounts of complex clinical data in a relatively short amount of time, therefore, creating opportunities for early detection of disease, increasing the odds of accurate diagnosis, and improving the ability to make informed clinical …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 14–19 Read article