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480 articles for “Drug Delivery”
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Chitosan-Based Polymer Coatings for Antimicrobial Catheter Surfaces
Abstract: Catheter-associated infections (CAIs) remain a major clinical challenge. Microbial adhesion and subsequent biofilm formation on catheter surfaces significantly reduce the effectiveness of antimicrobial therapy, resulting in prolonged hospitalization, increased healthcare costs, and higher patient morbidity. Consequently, the development of antimicrobial polymer coatings has emerged as an effective strategy for minimizing catheter-associated infections while improving device performance. Among the various biomaterials investigated, chitosan has attracted considerable attention owing to its intrinsic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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Targeted Delivery of Nanoparticle Based Taxanes for Breast Cancer Treatment: A Review
Abstract: The most common type of cancers in women is breast cancer. In United States, it is the second common cause of death in women. Metastatic cancer is the advanced stage of breast cancer, which is related to the distribution of cancerous cells from breast tissues to different areas of the body. Over the past numerous years, taxanes are bound to perform a huge role in the management and treatment of …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 36–51 Read article
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Recent Advances in Nanobiotechnology: Applications and Future Perspectives
Abstract: Nanobiotechnology is a rapidly growing field that combines the principles of nanotechnology with biology, medicine, and biotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various fields, including drug delivery, imaging, biosensors, tissue engineering, and nanomedicine. The article also discusses the challenges and future prospects of nanobiotechnology. This review article provides an overview of recent advances in nanobiotechnology and their applications in various …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 3, 2022 · pp. 43–47 Read article
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Lactoferrin Nanoparticles as Therapeutic Agent for Infectious Diseases
Abstract: Lactoferrin (Lf) is a mammalian cationic iron-binding glycoprotein, present in many mammalian excretions and supporting newborn growth to food and pharmaceutical applications. It possesses antibacterial, antimicrobial, antiviral and antiparasitic activity thus, making it an important part of the host defense system. This review focusses on recent therapeutic advances of the natural bioactive protein Lf and its use as a potential treatment agent. Nanoparticles have been tremendously used for several clinical …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 7, Issue 3, 2018 · pp. 37–40 Read article
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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AQUASOMES: A Vesicular, Self-assembled Ceramic Nanoparticulate Drug Carrier
Abstract: Nano-biopharmaceutics involves delivery of biopharmaceutical product through different biomaterials like multi-functional nanoparticles, quantum dots, aquasomes, super-paramagnetic iron oxide crystals, and liposomes dendrimers. Aquasomes are considered as one of the most recently developed delivery systems for bioactive molecules like peptides, proteins, hormones, antigens and genes to specific sites. Aquasomes have a spherical shape and a particle size of 60–300 nm. These are three layered self-assembled nano-particulate carrier system. This three-layered structure …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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Maximizing In Situ Formulation Adhesion Potential By Testing Different Polymer
Abstract: This study explores the use of a in-situ ocular gel delivery system for gentamicin sulphate. The anatomy of human eye consists of the cornea, lens, aqueous humor, vitreous humor, and retina. The physiology of the human eye involves the production of tears and the process of accommodation. Eye infections are caused by viruses, fungi, bacteria, or parasites. The symptoms of eye infection can include redness, itching, burning, watering, discharge, and …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 1–10 Read article
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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Initiatives of Nanotechnology to Combat Diabetes Mellitus
Abstract: Diabetes is the single most important metabolic disease which can affect approximately every organ system in the body. It has been projected that 300 million individuals would be affected with diabetes by the year 2025. In India, it is estimated that presently 19.4 million individuals are affected by this deadly disease, which is likely to go up to 57.2 million by the year 2025. It is imperative that effective monitoring …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 3, Issue 2, 2013 · pp. 38–47 Read article
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Microneedles and the paradigm shift in the field of dentistry: A Review Article
Abstract: Needle-based instruments are advancing as a promising tool for both diagnosis and treatment within the medical realm. They possess versatility, being capable of drug delivery and fluid extraction, catering to both systemic and local requirements. Unlike traditional drug delivery methods, which necessitate repeated dosing in the oral cavity due to saliva presence, there's a growing demand for delivery systems like needle-based devices that can offer sustained drug release orally. These …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 4, 2024 Read article
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A Review on Novel Emulsification Technique: A Nanoemulsion
Abstract: Kinetically stable and isotropic system of submicron size range is the nanoemulsion. In this system two immiscible liquids are mixed together to form a single-phase system with the identical concentration and ratio of surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20- 200 nm. Some literature suggest this range below 100 nm with shows narrow size distribution. In this review, major focus is given on the …
Published in Trends in Drug Delivery · Vol. 3, Issue 2, 2016 · pp. 25–34 Read article
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Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
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Liposome and Its Method of Preparation: A Review
Abstract: Liposomes are spherical vesicles that self-assemble and range in size from 20 nm to 10 m. They can be used as drug carriers for lipophilic, hydrophilic, and amphiphilic medications. Lipophilic and amphiphilic drugs can be encapsulated inside the lipophilic bilayer, whereas hydrophilic drugs can be integrated into the aqueous heart. Many liposomal preparations are currently undergoing clinical trials, with some of them being accepted for clinical use. By altering the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 25–30 Read article
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Comparative Study on Oro Dispersible Tablets of Candesartan Cilexetil Formulated with Natural and Synthetic Disintegrants
Abstract: Candesartan cilexetil, a BCS class II drug with low aqueous solubility and poor bioavailability (15%), poses challenges for oral delivery. To address this limitation, the present study focuses on polymer-based inclusion complexation and composite formulation strategies to enhance solubility and dissolution behavior. The drug was incorporated into β-cyclodextrin (β-CD), a cyclic oligosaccharide polymer, by the kneading method in different drug-to-carrier ratios. Among these, the 1:1 molar ratio complex exhibited the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 687–695 Read article
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Polymer Chemistry and Its Applications in Pharmaceutical Composite Formulations
Abstract: Polymer chemistry plays a critical role in pharmaceutical formulations, particularly in enhancing drug stability, bioavailability, and controlled release. Polymers are widely utilized in drug delivery systems. Polymers are widely used in pharmaceutical sciences for drug delivery, controlled release, and stability enhancement. This paper explores the role of polymers in the extraction and formulation of glycyrrhetinic acid from Glycyrrhiza glabra, a bioactive compound. Various polymer-based extraction and purification techniques are discussed, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 216–221 Read article