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1091 articles for “similarities”
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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A review on Advanced Materials for Sustainable Innovation and Innovative Applications in Chemical Engineering
Abstract: High level materials assume a vital part in driving feasible mechanical headways across different enterprises. This comprehensive review paper aims to provide an in-depth analysis of the properties, synthesis methods, and potential applications of advanced materials, focusing particularly on nanomaterials, biomaterials, and smart materials. These materials exhibit unique characteristics that render them indispensable for a wide array of applications, spanning energy storage, environmental remediation, healthcare, and electronics. Nanomaterials, characterized by …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 · pp. 59–79 Read article
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A Pre-experimental Evaluation of a Structured Educational Program on Awareness of Mosquito-borne Diseases in Senior Secondary School Students in Punjab
Abstract: Introduction: Mosquitoes constitute the most important single family of insects from the standpoint of human health. They are found all over the world. The four important groups of mosquitoes in India that are related to disease transmission are the Anopheles, Culex, Aedes, and Mansonia. Aims: The aims of the study are to assess the effectiveness of structured teaching program on knowledge regarding mosquito-borne diseases among students of senior secondary schools …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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A Study to Assess the Prevalence of Tokophobia and the Effect of Nurse-led Intervention on Birth Experience Among Parturients Availing Services in a Tertiary Care Hospital, Kolkata
Abstract: Introduction: Tokophobia, the fear of childbirth, can significantly impact a woman's birth experience and overall well-being. This study aims to determine the prevalence of tokophobia among parturients and evaluate the effectiveness of a nurse-led intervention in improving birth experiences in a tertiary care hospital in Kolkata. Methods: A cross-sectional study design was employed to assess the prevalence of tokophobia among parturients receiving services at the selected tertiary care hospital in …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Reasons For Not Studying in The Young Generation and Its Solutions
Abstract: Two decades ago, the education process in Afghanistan was promoted more than before, the level of literacy increased, many public and private schools, universities, and other semi-higher education institutions were established, numbers of printing houses and publications were created, and many magazines and other types of books were printed every month. The culture of learning and studying was moving forward rapidly. Unfortunately, in the last decade, the learning and studying …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 2, 2024 · pp. 34–41 Read article
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Can Screw-only fixations of ACPHT acetabular fractures enhance stability as the standard buttress plate fixation provides?
Abstract: Background: Of acetabular fractures, anterior column posterior hemi-transverse(ACPHT) fractures commonly occur after a fall onto the hip in elderly population. When displaced in these fractures, open reduction and internal fixation using plate and screws is usually required to achieve good functional outcomes. The open procedures, however, involve high complication rates due to surgical invasion; therefore, percutaneous techniques by screw-only constructs have been advocated to minimize these complications. The purpose of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 64–73 Read article
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Cultural Geomorphological Investigation of the Area around Twelve Jyotirlinga in India
Abstract: The cultural geomorphological investigation of the area around the twelve Jyotirlinga in India presents a comprehensive scientific exploration of the geological and geomorphological aspects of these sacred sites. Originally believed to be 64 in number, the twelve Jyotirlinga represent the most revered and holy places dedicated to Lord Shiva. These temples, distributed across the Indian subcontinent, exhibit a remarkable geographical arrangement in a distinctive spiral pattern. Based on aerial positions …
Published in Journal of Remote Sensing & GIS · Vol. 15, Issue 1, 2024 · pp. 47–70 Read article
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Computational Screening of Vitex negundo Compounds for Potential Arthritis Therapies in India
Abstract: Objective: Arthritis is a pervasive medical condition that manifests as inflammation and discomfort within the joints. As of September 2021, arthritis has affected an estimated 180 million people in India, making it a substantial public health concern with a considerable impact on individuals' quality of life and healthcare systems. Therefore, using molecular docking, drug-likeness prediction, and ADME analysis, an effort was made to identify natural compounds from Vitex negundo, which …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 01–18 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuranfrom Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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Lignin-modified bitumen: Exploring characteristics and performance
Abstract: The surge in crude oil prices has sparked interest in finding efficient and cost-effective alternatives to bitumen, a binder used in road pavement. Bitumen, derived from crude oil distillation or natural deposits, is primarily utilized in pavement grade bitumen, accounting for 83% of its usage. However, traditional hot mix asphalt, which relies heavily on bitumen, emits significant amounts of CO2, CH4, and N2O, contributing to environmental concerns. To address these …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 24–30 Read article
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Analysis and Simulation of VLAN Using Cisco Packet Tracer
Abstract: The acronym for Virtual Local Area Network, or Virtual LAN, is VLAN. We build this unique network from one or more pre-existing LANs. In order to provide scalable, dependable, and secure services regardless of location, today's networks must always be accessible from anyplace. Reducing users and workgroups that are separated is the main objective of a network. Each system must have the ability to interact with other systems and transmit …
Published in International Journal of Satellite Remote Sensing · Vol. 1, Issue 2, 2023 · pp. 28–33 Read article
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Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
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Harnessing the Potential of Virtual Instrumentation
Abstract: The Virtual Instrument (VI) uses custom software and hardware to create a user-defined measurement system, called a Virtual Instrument. Virtual instruments are similar to traditional instruments, such as multimeters, oscilloscopes, spectrum analyzers, and data acquisition systems. It has great flexibility, high performance, flexibility and low cost. Primarily, it consists of a personal computer or workstation, and Vi software such as LabVIEW, NI DAQmx, and MATLAB. This modular hardware includes data …
Published in Journal of Microwave Engineering and Technologies · Vol. 11, Issue 1, 2024 · pp. 1–15 Read article
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Analysis of new Floating Offshore Wind Turbine under drag force operation
Abstract: The goal of this paper is the study and analysis of a new type of floating offshore wind turbine (FOWT), which operates under drag force instead of lifting force as the conventional FOWT. We simulate the wind turbine operation modifying the pitch angle to faithfully reproduce the behavior when submitted to waves’ movement. The analysis of the wind turbine performance is developed in a model at laboratory scale to control …
Published in Journal of Offshore Structure and Technology · Vol. 11, Issue 1, 2024 · pp. 1–10 Read article
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A Critique of Advanced Instrumentation for Supervising and Regulating Renewable Energy Systems
Abstract: The integration of renewable strength property into the power grid necessitates modern-day tracking and manipulate systems to ensure highest best average overall performance, reliability, and performance. This paper offers a comprehensive analysis of advanced instrumentation applied for monitoring and controlling renewable strength systems. Beginning with an outline of renewable energy assets and their importance in addressing environmental worries and electricity sustainability, the compare delves into the challenges inherent in monitoring …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–12 Read article
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Numerical simulation and Artificial neural network illustration of phase-change material integrated into lattice structures printed in 3D
Abstract: This work examines the phase change material (P.C.M.) deposited in various lattice formations—such as “S.C., B.C.C., and F.C.C”.—at varied characteristics. The test concentrates on comprehending heat transport properties and thermal activity throughout the “melting and solidification processes”. The heater's maximum temperature, P.C.M. “melting and solidification”, and Nusselt number are among the essential factors examined. According to the findings, the heater's maximum temperature drops as porosity increases. Although the Nusselt values …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 175–183 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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A Secure and Transparent Voting System Leveraging Ubiquitous Computing and Blockchain Technology
Abstract: Ubiquitous computing and blockchain technology are two pivotal innovations driving significant changes in the digital world. This article explores the intersection of these technologies, analyzing how their combination can unlock new opportunities and address existing challenges. Ubiquitous computing envisions seamlessly integrating computing capabilities into everyday objects and environments, aiming to enhance user experience and efficiency. Meanwhile, blockchain technology, known for its decentralized and secure nature, offers robust solutions for transparency, …
Published in Journal of Advancements in Robotics · Vol. 11, Issue 2, 2024 · pp. 9–13 Read article
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Effectiveness of RMC Intervention on Knowledge, Attitude and Practice of Nurses and Maternal Perception
Abstract: A preliminary investigation was undertaken to create and assess the impact of RMC (Respectful Maternity Care) interventions on the knowledge, attitudes, and practices of nurses, as well as maternal perceptions regarding RMC, within maternity units at specific hospitals in Chandigarh. A quasi-experimental research design was utilized for data collection from nurses, while a post-test only design was employed for collecting data from mothers. A preliminary investigation, constituting 10% of the …
Published in Journal of Nursing Science & Practice · Vol. 14, Issue 2, 2024 · pp. 26–31 Read article