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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Photocatalysis Unveiled: Fundamentals, Mechanisms, and Material Innovations
Abstract: The Industrial Revolution significantly enhanced living standards but also led to severe environmental degradation, making pollution a critical concern for both developed and developing nations. Photocatalysis, a light-driven chemical process, accelerates thermodynamically demanding reactions, such as photosynthesis, offering a promising alternative for deep solar energy storage. This method also minimizes chemical exposure and reduces environmental pollutants generated by industrial activities. A key advantage of photocatalysis is its ability to replace …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 08–18 Read article
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Synthesis, Spectral Characterization and Computational Studies of Hydrazine Derivative
Abstract: (E)-1-(2,3-dimethoxy benzylidene)hydrazine (2,3-DMBH) is synthesized by condensation reaction. FT-IR, ¹H NMR, ¹³C NMR spectra were recorded for this compound. The synthesized compounds were evaluated as potential drug candidates through ADME analysis and Lipinski’s rule verification. Molecular docking studies against six proteins using AUTO DOCK software showed promising results. Among them, 2,3-DMBH exhibited strong binding affinities, particularly with 3ERT (-5.44 kcal/mol), followed by 5F90, 7E9B, and 3EWD. These findings suggest that …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 2, 2025 · pp. 1–17 Read article
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Synthesis of Novel Hybrid Biocomposites and Experimental Investigation of Mechanical Properties
Abstract: As industries increasingly adopt additive manufacturing, the demand for materials that offer better mechanical properties and functionality is on the rise. The purpose of present research work is to develop a novel hybrid biocomposites for 3D printing applications. The acacia bark, waste powder obtained from wet mahanarayan oil consisting of herbs and other bio filler was added in polylactic acid (PLA) for synthesis of hybrid biocomposites filament by twin screw …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 1–12 Read article
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Current Developments In 4D Printing Technology
Abstract: The perception of four-dimensional (4D) printing expertise was prompted through the time dimension inclusion in three-dimensional (3D) printing. Many other industries, including engineering, health, and the arts, have revealed a great deal of attention it. Recently, innovations in bioscience have been established that can be implemented using 4D printing. The ability to integrate time with situational variations has many benefits, but perceptibility and adaptability are merely two. Smart material, stimulus, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 108–120 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Integration of Revit to Microsoft Project for Construction Project Management: A Comparative Analysis of Scheduling and Resource Allocation
Abstract: Building Information Modelling (BIM) has revolutionized the construction sector by having architectural, structural, and mechanical design on one 3D platform. Autodesk Revit application enables real-time updates and changes without increasing errors and omissions. Its parametric nature allows users to develop intelligent models, enhancing decision-making, resource allocation, and cost estimation. Revit's visual representation allows effective coordination and communication with stakeholders, promoting a higher degree of client satisfaction. The application and benefits …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 · pp. 13–46 Read article
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Engineering Sustainable Interior Materials: Performance Analysis of PLA Composites Reinforced with Banana Stem Fiber and Spent Coffee Grounds
Abstract: This study presents the development and classification of eco-friendly composite panels reinforced with spent coffee grounds (SCG) and banana stem fibers (BSF) for interior applications. Hybrid composites were fabricated using polylactic acid (PLA) as the matrix with a constant filler loading of 30 wt%, varying BSF:SCG ratios (70:30, 60:40, 50:50). Mechanical testing revealed that the 70:30 composite exhibited the highest tensile strength (42 MPa) and flexural strength (58 MPa), whereas …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 94–105 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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A Comprehensive Review of Metabolite
Abstract: Metabolites, tiny chemicals, are essential to physiology, signalling, and biological function. This extensive review classifies metabolites into primary and secondary categories by biological relevance. Alkaloids, flavonoids, and terpenoids contribute to ecological interactions and defence systems, while amino acids, nucleotides, and carbohydrates directly affect development and cellular function. The article examines metabolic pathways, mass spectrometry, NMR, and metabolomics, a growing field. Metabolites play a crucial role in various scientific and practical …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Exploring the Therapeutic Potential of Phytochemicals in Aloe Barbadensis Miller Through Molecular Docking for Ulcerative Colitis Management
Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation of the colon, often associated with immune dysregulation and oxidative stress. Natural compounds have gained significant attention as alternative therapeutic agents due to their efficacy and minimal side effects. Quercetin, a flavonoid abundantly found in Allium cepa (onion), has demonstrated potent anti-inflammatory and antioxidant properties. This study employs an in silico approach to evaluate the therapeutic potential …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 06–12 Read article
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Aerodynamic Effects of Wind on Multi-Story Structures: A Height- and Terrain-Based Analysis
Abstract: Wind loads are a critical consideration in the structural design of buildings, with direct implications for safety and serviceability. This study investigates the aerodynamic behavior of reinforced cement concrete (RCC) buildings under varying heights and terrain conditions, in accordance with IS: 875 (Part 3): 2015. 12 structural models representing 20 m, 35 m, and 50 m tall buildings were analyzed using extended three-dimensional analysis of building system (ETABS) across four …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article
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Webometric Indicators and Digital Impact: An Evaluation of Top Ten NIRF-Ranked Indian University Websites
Abstract: This paper compares the webometric performance and digital presence of the top ten NIRF 2025–ranked Indian universities through their official websites. Data regarding total links (internal and external), Google-indexed links, URLs, and the Web Impact Factor (WIF) were gathered and analyzed using Google as the main search engine. The data collection and interpretation are based on the use of link analysis tools and search engine optimization (SEO) techniques. The analysis …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 1, 2026 · pp. 1–9 Read article
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Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives
Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article
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Acetaminophen: Current Understanding and Future Directions in Pharmacology
Abstract: In this review, acetaminophen is described as one of the most widely used analgesic and antipyretic medications worldwide due to its effectiveness and reduced gastrointestinal toxicity compared with traditional NSAIDs. Its precise mode of action is still unclear despite widespread therapeutic use. Acetaminophen has little peripheral anti-inflammatory effect and largely acts within the central nervous system, in contrast to NSAIDs, which mainly block peripheral cyclooxygenase (COX) enzymes and lower inflammation. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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An Investigation on Influence of Gamma Irradiation and Doping on Chemical Structure and Optical Properties of Conducting Polypyrrole
Abstract: In this study the authors report on effect of gamma irradiation and doping (bromine, iodine and sulfate ion) on chemical structure and optical, electronic properties of poly pyrrole. Optical absorption spectrum of PPY shown absorption bands centered around 36.2.5nm (peak 1), 450 nm (peak2) and 525 nm (peak 3) positions Gamma irradiation resulted in broaden of peak A together with a band shift of 45- 525 nm and disappearance peaks …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Assessment of Groundwater Quality in Rumuodara, Rivers State, Nigeria
Abstract: The assessment of groundwater quality from selected borehole in Rumuodara, Rivers State, Nigeria was evaluated. The results of the physicochemical parameters revealed that pH ranged from 6.57-6.60, temperature: 26.10-28.54oC, turbidity: 1.57-2.96NTU, conductivity: 41.24-68.44 μS/cm, salinity: 26.10-50.37mg/l, total dissolved solid: 18.9-63.14mg/l, total hardness: 38.21-48.30mg/l, alkalinity: 55.30-70.17mg/l, chloride: 28.40-75.14mg/l, sulphate: 21.50-30.60mg/l, nitrate: 1.50-3.04mg/l, phosphate: 59.24-65.40mg/l, calcium: 37.81-45.27mg/l, Iron: 0.133-0.190mg/l, sodium: 16.70- 21.13mg/l, copper: 0.22–0.50mg/l, total suspended solid: 2.94-3.60mg/l, Lead: < 0.01mg/l-2.27mg/l, zinc: …
Published in Research & Reviews : Journal of Ecology Read article
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Parametric Study of Fused Deposition Modelling Process During Fabrication of Acrylonitrile Butadiene Styrene (ABS) Based Injection Molding Die
Abstract: The purpose of this study is to dictate an optimum process parameter during the fabrication of additively manufactured acrylonitrile butadiene styrene (ABS) based injection mold using fused deposition modelling methodology based additive manufacturing process and to assess the quality of the infection mold by analyzing the surface roughness of the injection mold, and the time taken in the manufacturing of the mold. The ABS PRO+ filament is used in manufacturing …
Published in Journal of Polymer & Composites · Vol. 10, Issue 1, 2022 Read article
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Flow Structures Around Proposed Bridge Piers
Abstract: The current study investigated the flow hydrodynamics around proposed bridge pier and made comparison with existing bridge pier. To quantify the flow structures around the piers, the flow and turbulence parameters are analysed to understand the interference of one bridge pier over another. The experiments were performed on recirculating channel of 15 m length, 0.89 m width and 0.65 m height. Instantaneous three-dimensional velocity data was recorded by acoustic Doppler …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 14–21 Read article
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The Study of Gravimetric Thermal Analysis and Some Physical Properties of a Binary Polymeric Mixture of Unsaturated Ester and Peach Seed Powder
Abstract: Strengthening polyester resin and increasing its hardening was studied by adding peach seed powder. We also studied how to change the thermal properties after strengthening the resin by adding different weight percentages of peach seed powder (5%, 10%, 15%). The thermal properties of polyesters were studied before and after cementing, which included thermogravimetric analysis (TGA) and treatment at different temperatures (21, 51, 81, 121, 151ºC.) The effect of acidic functions …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 33–46 Read article
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Experimental Investigations on Aluminium Composites Materials Using Stir Casting Process
Abstract: In physical operations, accoutrements in motorcars and aeronautical machine factors, aluminium and its alloys are extensively used. In this study an effort is made to ameliorate the properties of aluminium essence matrix compound (A356) for manufacturing of machine rudiments taking High Tensile strength, Hardness, Wear resistance and low coefficient of friction, aluminium alloy (A356) reinforced with aluminium oxide, graphite and silicon carbide. In the current work, A356 as base metal …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 302–323 Read article