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296 articles for “pharmaceuticals”
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Unlocking Microbial Potential: Innovations in Natural Product Biosynthesis and Therapeutic Applications
Abstract: MNPs play a pivotal role in diverse fields, spanning medicine, agriculture, and industry. This review paper synthesizes insights from various discussions on microbial natural products, encompassing their sources, bioactive properties, and applications. We explore microbial diversity contributing to natural product synthesis, emphasizing bacteria and fungi as prolific producers. The methods for isolating and characterizing these compounds underscore the interdisciplinary nature of microbial natural product research utilizing various analytical techniques contributing …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 18–38 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
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Review on Bio and Chemical Reagents (Methods of Preparation and Uses)
Abstract: Among the organic compounds that are commonly used as chemical reagents in the field of pollution, removals of heavy metals from rivers, coordination chemistry and in various fields of life such as industry, medicine and pharmaceutical research are organic reagents such as oxime and imine azo reagents, Fehling’s and Tollen’s reagents and their derivatives. This type of reagent is characterized by high stability and rapid reaction with metal ions, as …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 2, 2025 · pp. 17–25 Read article
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Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
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Investigation of bio-physical interaction between Nanoparticles, Colloids, and biomolecules: Pharmaco-medical application.
Abstract: Currently, research into magnetic nanoparticles has become Popular. The fundamental principle involving the physics of magnetic nanoparticles is its interaction with biomolecules such as hemoglobin, DNA, and RNA. In this research, the nature Vander walls interactions, electrostatic repulsion, thermal interactions, and magnetic interaction between nanoparticles and molecule is explored. The interaction parameters such as Zeta potentials between layer, magnetic moment density, and Gibbs energy can are discussed by using DLVO …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 3, 2024 · pp. 6–17 Read article
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Sustainable Innovations in Green Nanotechnology for Nanoparticle Synthesis
Abstract: Green nanotechnology is an emerging field that focuses on the environmentally friendly production of nanoparticles through biological and sustainable processes. This approach has diverse applications across industries such as pharmaceuticals, energy, electronics, and bioengineering. Compared to conventional methods, biologically driven nanoparticle synthesis, particularly utilizing green chemistry principles, offers a safer, eco- friendly, non-toxic, and cost-effective alternative. Metal nanoparticles are commonly synthesized through top-down and bottom-up strategies using physical, chemical, and …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
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Modeling and Simulation of Feed Forward Temperature Controller with Effect of Higher Gain on Chemical Reactors Heat Exchangers
Abstract: Chemical reactors are widely used in pharmaceutical process industries. The temperature controller design is an essential part of heat exchangers (HE) design for such reactors. The goal of this research is to design and validate the Feed Forward (FF) temperature compensator for the stared tank chemical rectors. The aim is to analyze the impact of high turbulence (Gain) performance on step response. For temperature management, a transfer function (TF) control …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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Inventory of Healthcare Waste Generated at Kambia Government Hospital, Sierra Leone
Abstract: This research studies the categories and management practices of healthcare waste generated at Kambia Government Hospital and stresses the need for effective waste management to protect health and the environment. The waste is categorized into seven types: general, infectious, pathogenic, pharmaceutical, sharps, chemical, and liquid. Weekly assessments discovered fluctuations in waste generation, with general and infectious waste consistently comprising significant portions. Notably, sharps waste underscored the risks associated with injury …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 20–28 Read article
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A Comprehensive Review on Coumarin Derivatives
Abstract: Coumarins are naturally occurring compounds found in plants, fungi, and microorganisms with diverse bioactivities. They have antithrombotic, anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, and neuroprotective properties. Extracting coumarins, using methods like maceration and microwave- assisted extraction, is crucial for their applications. However, safety and toxicology are important, especially in pharmaceuticals, cosmetics, and food additives. Consuming moderate amounts of coumarin-rich foods is generally safe, but excessive intake raises concerns about hepatotoxicity and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 72–80 Read article
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Treated Sewage in Fish Farming and Ecological Challenges
Abstract: The use of treated sewage in fish farming presents a sustainable and cost-effective approach towards resource conservation and aquaculture productivity. Treated sewage is enriched with essential nutrients, like nitrogen and phosphorus, which supports the growth of aquatic plants and phytoplankton. These are vital components of aquaculture ecosystems. This practice reduces freshwater dependency and mitigates waste disposal challenges as well as aligns with circular economy principles. Pilot projects in China and …
Published in International Journal of Marine Life · Vol. 2, Issue 1, 2025 · pp. 26–31 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Optimization Of Solar Drying Parameters for Turmeric and Papaya Leaves: Effects on Nutritional and Bioactive Compound Retention
Abstract: This study focuses on the optimization of solar drying parameters for turmeric and papaya leaves, based on their impact on retention of nutritional and bioactive compounds. One of the most crucial postharvest procedures is solar drying as it decreases the moisture content in plant materials, thereby increasing shelf life and preserving quality. This study considers traditional methods as open sun drying (OSD) and advanced solar dry techniques, including Hybrid Indirect …
Published in International Journal of Electrical Power and Machine Systems · Vol. 3, Issue 1, 2025 · pp. 29–37 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Chemiluminescence: Recent Developments and Photochemical Applications in Analytical Chemistry
Abstract: Chemiluminescence (CL) is the observable production of electromagnetic radiation from a chemical reaction, typically in the form of ultraviolet, visible, or infrared light. According to subjective yield, CL has either been directly emitted from electronically excited intermediate products, or it has been supported by another molecule to emit CL. Since the 1950s, CL has been supported as a valid analytical tool, with the descriptive issued scope being limited to content …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 20–25 Read article
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Review on Sustained Released Matrix Tablet
Abstract: Pharmaceuticals often use sustained release dose forms to prolong the therapeutic agent’s presence in the bloodstream and maintain a consistent plasma profile. The matrix governs the drug’s release rate. Hydroxypropyl methyl cellulose, a release retardant, is a key excipient in formulations due to its ability to promote sustained release. Techniques that include wet granulation, direct compression, or the dispersion of solid particles within a porous matrix, integrating polymers, like polymethyl …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 60–69 Read article
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CdS-Based Photocatalytic Nanostructures: A Promising Material for Various Environmental Applications
Abstract: Modern technological and industrial progress has significantly increased the use of chemicals in product development, leading to greater contamination of water sources by conventional pollutants (such as organic dyes and heavy metals) and harmful microorganisms. Wastewater treatment processes now reveal “emerging pollutants,” including pharmaceuticals, endocrine disruptors, and agricultural chemicals. Certain emerging pollutants, though harmless in some cases, can pose serious risks to various organisms. To address this, researchers are exploring …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 33–53 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Harnessing Microalgae for Wastewater Treatment: Industrial Prospects and Environmental Benefits
Abstract: Simultaneous pollutant removal and biomass valorization has made microalgae an attractive and innovative solution to wastewater treatment, which could be considered a sustainable, low cost, and low energy approach. Considering their ability to store carbon dioxide, resorb nutrients, and produce valuable bioproducts, they represent an alternative with ecological potential to other previously used treatment methods. This review discusses how microalgae are used in industrial applications including biofuels, pharmaceutical, cosmetic, agriculture, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article