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588 articles for “identification”
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Driving Digital Transformation with Robotic Process Automation
Abstract: Compared to conventional administration methods, robotic process automation (RPA) has a number of advantages. Without a less intrusive mechanical hurdle, it allows for cost savings and resource liberation. Other benefits include more output, greater precision (and fewer errors), the potential to streamline regulatory compliance, quicker service (and hence higher customer satisfaction), and more uniformity. A description of business and digital transformation using procedure technology.The creation and use of computer-generated robots …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 1, 2023 · pp. 27–31 Read article
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Evolving Face of Quality in The World Robotics Process Automation (RPA)
Abstract: Robotics Process Automation (RPA) is a technology that automates repetitive and rule-based tasks using software robots or "bots." These bots mimic human interactions with digital systems and perform tasks like data entry, validation, report generation, and system integration. RPA leverages AI and ML to improve operational efficiency and can be applied across industries and functions. Implementing RPA offers benefits such as error reduction, productivity enhancement, and cost savings. RPA is …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Valeton Phytoconstituents from Curcuma Phaeocaulis as Prion Protein Mutant V210I Inhibitors: A Computational Docking and Virtual Screening Study
Abstract: Objective: Creutzfeldt-Jakob disease (CJD), a neurological disorder that is sporadic, fatal, communicable, and worsens rapidly, is caused by abnormal folding of prion proteins. Identifying and assessing the potential of phytocompounds from the Curcuma phaeocaulis Valeton plant as a new therapeutic candidate aimed at the treatment of CJD is the objective of this research article. Methods: In this experiment, we assessed outcomes following an in-silico assessment to design a new oral …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Navigating the Depths of Cancer Stem Cells: Unraveling Resistance Mechanisms and Emerging Therapeutic Strategies
Abstract: In the past few decades, comprehensive evidence has convincingly established the presence of cancer stem cells (CSCs) as a minor subset within tumors, contributing to an unusually elevated level of cellular diversity within the malignancy. CSCs are functionally identified by their capacity for self-renewal and differentiation, frequently influenced by signals from their surrounding microenvironment. The interconnected transcriptional, post-transcriptional, metabolic, and epigenetic regulatory networks govern the biological characteristics of CSCs. CSCs …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 14–18 Read article
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Dengue in India : Insights in the Indian Context
Abstract: The mitigation of infectious diseases in India, notably Dengue, assumes pivotal importance due to their significant repercussions on human and animal health, thereby imposing a considerable burden on the healthcare infrastructure. This review underscores the ongoing initiatives in infectious disease management, endorsing the implementation of a comprehensive healthcare strategy. Emphasis is placed on the augmentation of reporting mechanisms through the integration of IgM detection kits, advocating for heightened investments in …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 10–13 Read article
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Evaluating the Efficacy of a Self-instructional Teaching Module on Home Care Management Knowledge for Renal Failure Patients Undergoing Hemodialysis in a Selected Hospital in Ambikapur, Chhattisgarh
Abstract: The kidneys, with their remarkable organization and precision in regulatory functions, exhibit a level of sophistication that can be likened to a divine quality. In a conducted study, a substantial correlation was identified between the pre-test knowledge scores of participants and specific demographic factors, particularly educational qualifications. The chi-square values calculated for educational qualifications were 18.85, and for previous knowledge, it was 6.56. In both instances, the calculated values surpassed …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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An Interoperability on the Internet of Things (IoT): A Review
Abstract: With technological advancement growing at a rapid rate, we are presented with numerous ways of connecting ourselves to the rest of the world. The Internet of Things, or IoT, is now a reality, even at the minuscule level. With ubiquitous computing, we can stay in constant communication with the outside world. As such there are several types of devices capable of monitoring, measuring, and sending data back and forth from …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 1, 2023 · pp. 40–53 Read article
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Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
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A review on antibacterial properties of eucalyptus oil and different eucalyptus species used in pharmaceuticals
Abstract: Medicinal plants with antimicrobial compounds play a crucial role in combating various pathogens. Eucalyptus, belonging to the myrtle family, is notable for its diverse antimicrobial compounds. This fast-growing plant thrives in many countries and its various parts offer significant medicinal value, including timber, pulpwood, and essential oils. The leaves, often considered forest harvesting waste, contain essential oils with potential medicinal benefits. Members of the genus Eucalyptus are highly valued for …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 10–19 Read article
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Blockchain and Smart Contract Based Decentralized Rental Platform
Abstract: The advent of blockchain technology has emerged as a revolutionary influence in contemporary society, restructuring engagements and commerce. It is characterized by a decentralized and distributed network of blocks storing information with digital signatures. Initially developed for digital cryptocurrencies like Bitcoin and Ethereum, blockchain has expanded its utility across various domains, leveraging its core features of decentralization, persistency, anonymity, and auditability. Originally designed for cryptocurrencies, blockchain technology has extended its …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 2, 2023 · pp. 18–24 Read article
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A Pilot Study on β-lactamase Producing Escherichia coli from Bovine Milk, West Bengal
Abstract: Drug resistant bacteria have become a significant global healthcare issue that requires close attention. With regards to antibiotic resistance, E.coli and its Enterobacteriaceae family are highly notorious for their ability to swiftly spread antibiotic resistance genes, thereby posing a major concern. In order to effectively address the spread of multi drug resistant bacteria, ongoing monitoring of the microflora in milk for the presence of drug resistant genes is essential. This …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 01–05 Read article
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A Rare Case of Serous Cystadenoma Ovary with Cholesterol Granuloma in an Adult Female
Abstract: In reaction to cholesterol crystals and foreign body giant cells, cholesterol granulomas are formed. These are the results of long-term inflammation brought on by the buildup of cholesterol crystals in tissues. The middle ear and paranasal sinuses are the most often reported locales; however, the mediastinum, breast, and ovary have all been implicated in a small number of cases. Here, we report a rare instance of an accidental ovarian cholesterol …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 13–17 Read article
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Smart Traffic Management Systems: A Comprehensive Review of Existing Solutions
Abstract: In our nation today, when the number of automobiles keeps growing faster than the resources at our disposal, managing this problem is getting harder, and things get worse when accidents happen. Numerous facets of society are impacted by this issue, such as time wasted, health problems, pollution, traffic accidents, and economic progress. According to this paradigm, individuals can rely on traffic control technologies to reduce traffic and its consequences. We …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 27–32 Read article
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Effectiveness of structured teaching programme on knowledge regarding ECG and its basic interpretation among second semester BSc Nursing students in selected nursing college at Pathanamthitta district
Abstract: Cardiovascular diseases have now become the leading cause of mortality in India. Cardiovascular disease accounts for twenty five percent of all mortality. Electrocardiogram has an important role in the early detection and treatment of various cardiovascular diseases. Over the year significant advancements have been made in the field of ECG research, leading to the development of new techniques, technologies and algorithms for ECG analysis. ECG allows nurse to diagnose and …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 09–20 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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Harnessing the Medicinal Potential of SwertiaChirata: A Phytochemical Strategy for Controlling Coronavirus Symptoms Like High Fever and Anxiety
Abstract: The current investigation focuses on exploring the therapeutic capacities of SwertiaChirata, colloquially known as Chirata, in managing the symptomatic displays of coronavirus infections. Chirata, a member of the Gentianaceae family, is a distinguished herb extensively used in Ayurvedic and Unani medicinal traditions, acknowledged for its myriad of healing qualities. In addition to its regular use in combating fever and loss of appetite, its prominent antioxidant traits position it as an …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 27–31 Read article
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Development of an Innovative Nanotransdermal Formulation Utilizing an Optimal Combination of Acyclovir and Omeprazole to Improve Antiviral Efficacy
Abstract: The study effectively created nanogel formulations of Acyclovir and Omeprazole using the solvent diffusion technique. Among the various formulations (F1–F9), F9 was identified as the most suitable for gel preparation based on its pH evaluation. Drug content analysis, performed using UV-spectroscopy, confirmed the homogeneity of the prepared nanogels, which appeared opaque, free of lumps, particles, or aggregates. The spreadability assessment of F9 demonstrated excellent spreadability, while viscosity values for all …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 19–35 Read article