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588 articles for “computational modeling”
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Molecular Docking, QSAR Modeling, and ADMET Evaluation of Novel Pyrazolo-Pyrimidine Derivatives as Potential CDK-2 Inhibitors for Cancer Therapy
Abstract: Cyclin-dependent kinase-2 (CDK-2) is an essential regulator in cell cycle progression and is an important therapeutic target in cancer drug development. In the present study, an integrated computational approach involving molecular docking studies, QSAR modeling, ADMET prediction, and artificial intelligence-based analysis was used to identify pyrazolo-pyrimidine derivatives as potential CDK-2 inhibitors. Based on the molecular docking results, it was found that selected compounds exhibited high binding affinity towards the ATP …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Fluent Simulation & Analysis of Earth Heat Exchanger with Air as a Cooling Medium
Abstract: Because of the temperatures differential between the environment and the subsurface, an Earth Air Tube Heat Exchanger (EATHE) uses the thermal energy of the ground for air conditioners in the winter and air cooling in the summer. Everyone can lower the amount of energy needed for space heating or cooling with the aid of EATHE. However, it is challenging to create precise energy simulations and designs for calculating surface heat …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 11, Issue 1, 2024 · pp. 18–26 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Understanding Sentiment Trends Through Zero-Shot and Few-Shot Learning Models
Abstract: The requirement for large, manually labeled datasets is one of the main barriers to applying sentiment analysis algorithms in specialized or rapidly evolving disciplines in the present natural language processing (NLP) landscape. This work investigates a paradigm shift from traditional fully supervised learning to data-efficient methods, specifically zero-shot learning (ZSL) and few-shot learning (FSL). This study uses the advanced capabilities of instruction-tuned large language models (LLMs), like GPT-4, to assess …
Published in International Journal of Computer Science Languages · Vol. 4, Issue 1, 2026 · pp. 01–08 Read article
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IoT Integration in Sustainable Agriculture
Abstract: The increasing demand for food production, environmental concerns, and resource limitations have necessitated the adoption of Internet of Things (IoT)-based innovative farming solutions. The current paper introduces an IoT-based system that integrates hydroponics, aquaponics, and poultry to promote sustainability, resource utilization, and agricultural productivity. Conventional farming practices are riddled with ineffective use of resources, uncertain environmental effects, and expensive operations. The new system facilitates real-time monitoring, automated decision support, and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 2, 2025 · pp. 69–84 Read article
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Cyclist Safety Enhancement: A Multi-Modal Hazard Detection System
Abstract: This study presents a multi-modal hazard detection system to enhance cyclist safety in urban environments. Lever- aging a combination of computer vision, object tracking, and predictive modeling, the system offers a comprehensive approach to identifying and mitigating potential risks. Key contributions include improved depth estimation through object size priors, multi-class tracking utilizing KCF and Brisk, and a novel recurrent neural network architecture for predicting bicycle movement. The system’s collision detection …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 2, 2023 · pp. 35–83 Read article
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Thermo–Electrical Performance Enhancement of a Lightweight Polymer–Metal Hybrid Electrostatic Precipitator Using Epoxy-Based Composite Housing for Industrial Particulate Control
Abstract: Airborne particulate emissions, particularly PM₁₀ and PM₂.₅ produced by industrial activities and combustion processes, they continue to pose a significant threat to both the environment and public health. Electrostatic precipitators (ESPs) are widely recognized for their ability to achieve high collection efficiencies; however, conventional metallic constructions often lead to increased system weight, higher fabrication costs, and long-term corrosion-related challenges. In this study, a lightweight hybrid material approach is proposed by …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 652–668 Read article
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Experimental Analysis and Design Proposal of Banana Fiber Reinforced Polymer Composites and Computer Analysis
Abstract: This study presents a comprehensive experimental investigation and design model development using banana fiber reinforced polymer (BFRP) composites. The primary aim is to evaluate the mechanical and physical performance of the composite, with particular emphasis on tensile strength, flexural strength, and water absorption characteristics. These properties are critical for applications in industries such as transportation and construction, where durability, lightweight materials, and cost-effectiveness are essential. Banana fibers, being natural, renewable, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 901–907 Read article
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Study of Proximity Points and Fixed Points
Abstract: This paper explores the concepts of proximity points and fixed points, which are fundamental in mathematical analysis and nonlinear functional analysis. Fixed-point theorems play a crucial role in optimization, game theory, differential equations, and dynamic systems. Proximity points, an extension of fixed points, provide a more generalized approach, allowing near-coincidence rather than exact identity. The study discusses classical fixed-point theorems, such as Banach’s contraction principle, Brouwer’s fixed-point theorem, and Schauder’s …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 28–31 Read article
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A Smart Framework that Combines Data Mining and Optimization for Different Applications
Abstract: Blending predictive data mining with metaheuristic optimization has become essential for tackling tough, real-world problems across all kinds of fields. Most existing methods stick to fixed algorithms, each focused on a tiny slice of the puzzle, barely budging when new variables or unpredictability show up—especially with messy, human-generated data. So, here’s the idea: a Unified Metaheuristic and Predictive Data Mining (UMPDM) framework that finally connects adaptive search methods with powerful …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article
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Early Lung Cancer Prediction using deep Learning
Abstract: Lung cancer is a global killer because it’s often found late. Finding it early is key to treatment and survival so computer assisted diagnostics are essential. This research uses deep learning to spot early stage lung cancer from CT scans. We trained and fine-tuned three convolutional neural networks—ResNet50, Dense Net 201 and EfficientNet-B0—using transfer learning. We preprocessed the lung CT images by resizing, normalizing and augmenting them to enhance the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 Read article
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An Intelligent Modelling system for Automotive Vehicles
Abstract: In this paper it’s about the development of artificial intelligence that has fuelled technological advancements. Self-driving automobiles are an example of an innovative development. Nowadays, you may work or sleep in your car while driving to your destination without touching the steering wheel or accelerator. This project aims to create a workable model of a self-driving car capable of traveling on multiple tracks, including curved, straight, and straight followed by …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 1, 2025 · pp. 32–40 Read article
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Genomic Selection for Grain Yield in Wheat Using Machine Learning on DArT Molecular Markers: A Comparative Evaluation Across Multi-Environment Trials
Abstract: Genomic selection (GS) predicts complex quantitative traits directly from genome-wide molecular markers, bypassing the need for extensive phenotypic trials and accelerating plant breeding cycles. We conducted a comparative evaluation of seven regression approaches — ridge regression (the machine-learning equivalent of RR-BLUP), Lasso, Elastic Net, Partial Least Squares, linear Support Vector Regression, Random Forest, and Gradient Boosting — for predicting grain yield from 1,279 Diversity Array Technology (DArT) molecular markers genotyped …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 2, 2026 Read article
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Application of Artificial Neural Networks in Optimizing Polyhouse Roof Truss Design
Abstract: Polyhouses are specialised agricultural structures developed to maintain controlled environmental conditions for crop cultivation, thereby ensuring consistent productivity even under adverse climatic circumstances. The performance of these systems largely relies on the structural stability and cost efficiency of the roof truss, which must achieve an effective balance between strength, adaptability, and economy. In this research, an Artificial Neural Network (ANN)-based modelling framework is introduced to optimise the members of polyhouse …
Published in Recent Trends in Civil Engineering & Technology · Vol. 16, Issue 2, 2026 · pp. 15–25 Read article
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Autonomous Scripting: The Future of AI-Enhanced Shell Programming for DevOps and Security
Abstract: The evolution of operating systems has seen a paradigm shift with the integration of artificial intelligence, quantum computing, and edge computing technologies. Autonomous scripting, driven by AI, is transforming DevOps workflows and security paradigms, enabling self-healing systems, predictive automation, and intelligent threat detection. This study explores the role of AI-enhanced shell programming in the automation landscape, discussing its implications for next-generation operating systems. It further delves into the integration of …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 1, 2025 · pp. 28–39 Read article
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Blind Image Quality Assessment using NSS Approach in the DCT Domain
Abstract: We have develop an efficient model for improving image quality using IQA and NSS based on blind image Quality Assessment. This algorithm does computation for the parameters which user expect at output. The certain extracted features approach depends on a simple Bayesian inference model to dipict image quality scores. The project features are based on statistic scenes of discrete cosine transform for images. The resultant parameters of the model are …
Published in Recent Trends in Electronics Communication Systems Read article
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Hand Gesture Recognition Systems: A Review of Vision-based and Sensor-based Approaches
Abstract: With many real-world uses, such as sign language translation and human-computer interaction, hand gesture detection is a crucial area of study in the science of computer vision. In this study, we propose a Convolutional Neural Network (CNN) model that uses real-time camera images to recognise hand gestures. A collection of hand motion photographs spanning the English alphabet (A-Z) was gathered, and the images were pre-processed to exclude any backdrop and …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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5 Pen PC Technology: A Portable Computer
Abstract: A recent advancement in the field of pen computing is known as “5 pen technology.” Computers have a considerably bigger impact on our lives than most of us may realize. Becoming proficient in computer software has become essential for most occupations. The ENIAC, the first computer ever created in 1943, had more power than several hundred contemporary PCs and was the size of a big room. Integrated circuit-based modern computers …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 2, 2023 · pp. 29–34 Read article
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Hybrid Techniques in Mango Leaf Disease Identification: Evaluating Neural Networks and Support Vector Machines
Abstract: Mango leaf diseases pose a significant threat to mango production, impacting both yield and fruit quality. Early and accurate detection of these diseases is crucial for effective management. This paper evaluates the use of hybrid techniques, specifically the integration of neural networks (NNs) and support vector machines (SVM), in the identification and classification of mango leaf diseases. NN excel in extracting complex features from images, while SVMs are robust classifiers, …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 3, 2024 · pp. 19–27 Read article