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419 articles for “Uses Pharmacological”
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Flower Morphology of Four Gladiolus Genotypes
Abstract: Angiosperms are plants which have covered fruits as compared to gymnosperms. Today these plants dominate the world in the aquatic, terrestrial as well as in aerial environment. Flora of any area determines types of vegetation over there, in addition, types of the animals in the area which constitute the ecosystem over there. In the community analysis of any area many kinds of the measurement are taken as parameters. In assessment …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 11, Issue 2, 2022 · pp. 29–37 Read article
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Evaluating the therapeutic effects of Asystasia gangetica (Chinese violet) on the chronic respiratory condition- Asthma
Abstract: Asthma is a chronic condition affecting the respiratory system. Its symptoms affect the immune pathways via helper T-cells. The plant Asystasia gangetica is prevalent throughout tropical regions around the world. It has been used in some herbal remedies to relieve symptoms of asthma. This study used computational techniques to assess the effectiveness of several phytocompounds present in A. gangetica in relieving symptoms of Asthma. Three proteins associated with asthma, namely …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 15–21 Read article
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Traditional and Ethno Pharmacological Aspects of Apang (Achyranthes aspera L.)
Abstract: AbstractHerbs are vital source of drugs from the ancient time holding the scenario of the Ayurvedic system of medicine. Since time immemorial, Achyranthes aspera Linn. along with other herbs has been used in different systems of medicine. Though almost all of its parts are used in traditional systems of medicines, seeds, roots and shoots are the most important parts which are used extensively. This review reveals that the plant possesses …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 2, 2013 · pp. 26–32 Read article
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Using Multitarget Molecular Docking to Examine the Antiviral Potential of Clerodendrum Phlomidis against Measles
Abstract: Objective: Measles, a viral disease caused by a member of the Paramyxoviridae virus family, is highly contagious and characterized by a respiratory illness and a maculopapular rash on the skin. Children are the main victims of the illness. In the context of drug development, this study investigates the efficacy of phytocompounds derived from Clerodendrum phlomidis against the target protein of the measles virus. Methods: The 7SKS protein was retrieved from …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 32–42 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Zebrafish in Drug Research: Decoding Biological Mechanisms and Finding Novel Therapeutic Targets
Abstract: The zebrafish, scientifically known as Danio rerio, is a powerful model organism in biological research because of its favorable traits, which include rapid development, genetic tractability, and transparent embryos. Zebrafish were first identified for their use in studies of vertebrate development, but they have since spread to a variety of disciplines, such as pharmacology, clinical research as a disease model, and most notably, drug development. Zebrafish have emerged as a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–8 Read article
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Phyto-Pharmacognostical Study of Zornia Gibbosa Span (Samyojaki)
Abstract: Recent survey shows that the plants extinction are occurring at rates hundreds of times higher than natural background rates, and 15,000 species of medicinal plants are now threatened. Under such circumstances the drugs which are abundantly available, common and cost-effective should be encouraged to control the extensive overuse of few classical drugs. Thus preventing them from verge of extinction and also reducing the chances of adulteration. Looking at the need …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 3, 2013 · pp. 24–32 Read article
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Prodrugs and Its Types
Abstract: In this study, description of prodrugs is given. Prodrugs are biologically inactive agents that upon biotransformation in vivo result in active drug molecules. Inactive prodrugs are pharmacologically inactive medications that are metabolized into an active form within the body. Depending upon the functional group, used to design the produrg, present in the parent drug, the pro drugs can be classified so many ways, which are given in this study. Keywords: …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 1, 2017 · pp. 1–8 Read article
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Review on Phytochemicals as Novel Therapeutic Strategies for the Treatment of Diabetes
Abstract: Diabetes is a worldwide concern. People are suffering from different variants of diabetes in the world, of which Type-1 and Type-2 diabetes are very common in the globe. In labor, gestational diabetes affects many ladies. Some other types of diabetes occur due to genetic changes and problems in pancreatic activity. Numerous Indians suffer from type-2 diabetes. Three diagnosis methods are employed for the detection of diabetes. The alteration in activity …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 2, 2022 · pp. 1–8 Read article
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Pharmacological and Nonpharmacological Management of Chronic Obstructive Pulmonary Disease (COPD): An Overview
Abstract: Chronic obstructive pulmonary disease (COPD) is a composite state with many characteristics that are agreeable to treatment. A well sympathetic of the physiology of COPD and better tackles to assess consequences have led to advances in our capability to cure this disease. Pharmacological methods can progress patients’ eminence of life significantly by dipping dyspnea and limiting exacerbations. Although, none of the drugs currently obtainable for COPD are able to deduce …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 2, 2023 · pp. 45–69 Read article
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A Review on Natural Radio-protective Agents
Abstract: AbstractRadioprotectors play crucial role in safeguarding biological system from various damages to DNA (Deoxyribonucleic acid), protein molecules, lipids by peroxidation as well as hematopoietic, gastrointestinal, reproductive and central nervous system exposed to radiation dose especially against radiation injury in cancer survival patients undergoing radiotherapy. As over 40% patients require this therapy, during the treatment where ionizing radiation is used to shrivel tumors and exterminate cancer cells by disrupting their DNA. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 20–31 Read article
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A Review on Biotechnological Aspects of Conservation and Enhancements of Indian Snakeroot (Rauwolfia serpentina)
Abstract: Indian snakeroot (Rauwolfia serpentina) is one of the most important medicinal plants found in the Indian subcontinent, used in the treatment of various types of diseases. Recently it has been considered as a critically endangered plant by the International Union of the Conservation of Nature and Natural Resources (IUCN) due to its heavy exploitation in the past. The plant has a high demand in the international market due to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 30–38 Read article
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Qurs-e-Kaknaj: An Effective Unani Compound Drug in Treatment of Lower Urinary Tract Symptoms (LUTS)
Abstract: Lower urinary tract symptom is a common presentation among elderly male patients and required a safe pharmacological composition to improve the quality of life in these patients. In recent years, there has been a shift in paradigm of medicine selection from synthetic to herbal medicine. Medicinal plants have been used in Unani System of Medicine since antiquity to treat ailments as rich source of therapeutic agent. Qurs-e-Kaknaj is a Unani …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 8, Issue 2, 2021 · pp. 9–17 Read article
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In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus.
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 4, 2023 Read article
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In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 2, 2021 · pp. 1–9 Read article
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Carica papaya Linn.: A review on Nutritional and Medicinal Value of Papaya
Abstract: Papaya (Carica papaya Linn.) is a popular fruit tree in the tropical part of the world. It is a delicious, sweet fruit with a pleasant aroma. The papaya is consumed worldwide as a fresh fruit and vegetable. which is healthy for humans because all parts of the plant, including fruit, stem, bark, peel, fruit, seeds, and pulp, have medicinal properties. Papaya also has nutritional value and is also used as …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 67–75 Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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In-Silico Docking of Rubia cordifolia Phytocompounds as Potential MMP-2 Inhibitors for Varicose Vein Management
Abstract: Varicose veins are one of the most common disorders, affecting the vein structure and function of lower limbs, yet there has been no absolute cure found yet. One of the underlying causes for worsening of the condition is the proteolytic activity of MMPs which are a group of enzymes that affect the extracellular matrix (ECM) surrounding the affected veins. Phytocompounds of Rubia cordifolia (Manjishta) were docked against the MMP-2 protein …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 31–42 Read article
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Aerva sanguinolenta (L) Blume: A Review on Morphology, Phytochemistry and Pharmacological Aspects
Abstract: In India, herbs have always been the natural form of medicine. Many of the most common medicines are developed from the components of medicinal plants. Aerva sanguinolenta (F: Amaranthaceae) is a pernennial herb found in tropical countries. It is commonly known as climbing wool plant. It is having many folklore medicinal uses like wound healing, anti-inflammatory, diuretic etc. As far as the available literature is concerned, this plant has not …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 2, 2016 · pp. 1–5 Read article
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Computational Analysis of Tinospora Cordifolia Phytochemicals as Potential Inhibitors of BRCA1-BRCT Domain Interaction in Breast Cancer
Abstract: Breast cancer is a leading cause of cancer-related deaths worldwide, accounting for a significant proportion of mortality rates among women. Despite current therapeutic approaches, the disease remains characterized by molecular heterogeneity, making it challenging to develop effective treatments. This study explores the potential of Tinospora cordifolia, a medicinal plant, in breast cancer therapy. Guduchi, scientifically known as Tinospora cordifolia, boasts a centuries-long history of use in traditional medicine, with a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 27–37 Read article