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1385 articles for “Specificity”
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Azepines, Chemistry, Synthesis and Reactions
Abstract: Azepines, which consist of a seven-membered cyclic compound featuring six carbon atoms, an additional nitrogen atom, and no double bonds between carbons, form a diverse group within organic chemistry. The fully hydrated form of this compound is called azepam (C6H13N). Compounds and their variants play crucial roles in pharmaceutical research due to their biologic attributes like cancer-fighting, bacteria-killing, fungus-busting, virus-suppressing, and inflammation-reducing capabilities. Various organic molecules found within nature draw …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 35–45 Read article
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Injection Pressure Optimization for Non-edible Biodiesel Blends in CRDI Engines: A Comparative Study
Abstract: The growing demand for clean and sustainable energy has increased interest in biodiesel produced from non-edible oil sources. These fuels are renewable, biodegradable, and do not compete with food resources. However, the effective use of biodiesel blends in modern diesel engines requires proper control of fuel injection parameters, particularly injection pressure. In common rail direct injection (CRDI) engines, injection pressure strongly influences spray formation, air–fuel mixing, combustion behaviour, and exhaust …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 24–34 Read article
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Assessment of Clayey Soils and Bentonite to Use as Compacted Clay Liner for the Disposal of Municipal Solid Wastes at Lucknow City, India
Abstract: Dumping of municipal solid wastes in a pit without liner causes groundwater contamination. Use of locally available clayey soils will be a cost-effective landfill technique. Mixing of locally available soils with bentonite reduces the permeability. To develop the liner for the disposal of municipal solid wastes generated from Lucknow city, India, the soil samples were collected from three different locations as nearby the Sagar Institute, Barabanki district; near railway crossing, …
Published in Journal of Geotechnical Engineering · Vol. 12, Issue 3, 2025 · pp. 62–71 Read article
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Polyurethane: Chemistry, Production, Applications, and Future Prospects—An Overview
Abstract: Polyurethane (PU), a class of versatile polymers, has emerged as one of the most significant materials in modern industry owing to its remarkable mechanical strength, elasticity, durability, and resistance to abrasion, chemicals, and environmental degradation. Its wide range of tunable properties has made PU indispensable across multiple sectors, including fashion, automotive, manufacturing, biomedical, coatings, and construction. This review emphasizes the diverse applications of polyurethane and explores how its unique chemistry …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 3, 2025 · pp. 17–25 Read article
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Disaster Preparedness and Response (Comparison Between Delhi, Mussoorie and Kerala)
Abstract: Disaster preparedness and response are critical for minimizing the adverse impacts of natural and man-made disasters. These practices play a crucial role in saving lives, reducing economic losses, and ensuring the resilience and recovery of communities. By prioritizing preparedness and response, societies can build resilience against the inevitable occurrence of natural and man-made disasters. This comparative analysis examines the distinct strategies employed by Delhi, Mussoorie, and Kerala, highlighting how each …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 2, 2025 · pp. 71–78 Read article
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Polymer Nanocomposites As Emerging Platforms in Pharmaceutical Nanotechnology
Abstract: Nanotechnology allows the handling of materials in the 1–100 nm range, where distinct physicochemical phenomena, including quantum effects and higher surface-to-volume ratio, enable disruptive uses in pharmaceuticals and biomedicine. Significant challenges in solubility, stability and targeted biodistribution of therapeutics can be overcome by incorporating nanostructured polymers and polymer-based composites into drug delivery systems. PLGA nanoparticle and other nanocarriers, such as PLGA micelles, dendrimers, and hydrogels, have revealed promising effects on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 268–278 Read article
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A Mini Review of Synthesis and Applications of Functionally Graded Materials
Abstract: Material composition or microstructure varies gradually along the thickness over a specific volume in functionally graded material (FGM) that results in spatial change in properties like thermal conductivity, strength, stiffness, electrical, magnetic, and light properties, etc. Application of the concept of FGM leads to a single product that has multiple properties in it as demanded by the operational or functional requirements of the product under service conditions. It also allows …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 54–65 Read article
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A Systematic Review of Advanced Composite Materials for High-Performance Spur Gear Applications
Abstract: This is a review which provides specific and detailed information regarding the fiber-reinforced polymer (FRP) composite to replace traditional steel in high-performance spur gears with emphasis on mechanical performance, computational modeling, and experimental validation. Methods: The current literature was thoroughly investigated that includes material properties, material simulation (e.g., finite element analysis, FEA), and experimental gear testing procedures (e.g., DIN 51354, ASTM G99). Certain case studies in the aerospace and automotive …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 209–220 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Leveraging Standards and Deep Learning Approaches to Secure Internet of Things (IoT) Devices from Cyber Attack
Abstract: The widespread adoption of Internet of Things (IoT) devices between 2019 and 2024 has significantly grows in various sectors in Japan, including healthcare, manufacturing, and the development of smart cities. Although this growth offers many advantages, it also makes these devices more vulnerable to cyber threats. High-profile security breaches in Japan have sparked discussions about the requirement for enhanced security measures to protect the rapidly evolving IoT technologies. This study …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 1, 2025 Read article
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Recent Progress in Magnesium Hybrid Metal Matrix Composites: Processing, Properties, and Applications
Abstract: Magnesium hybrid composites have emerged as promising materials to meet the growing demands of advanced sectors such as biomedical, aerospace, defense, automotive, electronics, and marine industries. However, the inherent drawbacks of magnesium, specifically low wear resistance, have encouraged scientists to develop magnesium-based MMC with improved mechanical properties and thermal properties. To achieve this, various mixtures of reinforcement are employed. These include ceramics with high strength and wear resistance; solid lubricants …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1287–1301 Read article
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Synthesis, Characterization and Dielectric Properties of Polymer Materials for Microwave Communication Applications
Abstract: The rapid advancement in wireless communication technologies has necessitated the development of advanced materials with tailored dielectric properties. Polymer materials, because of their flexibility, lightweight nature, and processing ease, are currently being used in initiatives to formulate low-dielectric materials specifically tailored for microwave communication applications. In the current investigation, the authors concentrate on the synthesis, characterization, and dielectric properties of five distinct novel polymer materials. The synthesized polymers are characterized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1482–1495 Read article
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An Investigation into the Quality of Distillate Diesel Fuel at Selected Service Stations in Freetown’s Western Area
Abstract: As a critical energy source for global transport and industry, diesel fuel quality is of paramount importance. This study evaluates and compares the quality of diesel fuel samples by analyzing key parameters: sulfur content, density, cetane index, and kinematic viscosity. The properties of diesel fuel samples from six (6) Fuel Stations of various Oil Marketing Companies (OMCs) are compared with National Technical specifications limits of the Sierra Leone Standards Bureau, …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–14 Read article
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A Secure Storage Model with Authentication and Optimal Key Generation Based Encryption
Abstract: In digital forensics, ensuring the secure storage of digital evidence is crucial. This paper introduces a new method that uses advanced encryption and key generation techniques to protect digital evidence throughout an investigation. Cloud forensics, a modern approach to digital forensics, aims to safeguard evidence from online hacking. However, storing all evidence in one central location can reduce its reliability. To address this, we propose a digital forensics architecture for …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 7–13 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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An Efficient Vision-Based Algorithm for Hand Pose Estimation and Cursor Control
Abstract: Conventional input devices like the keyboard and mouse are no longer necessary because gestures are becoming more popular as the most natural way to interact with computers. This project has demonstrated a novel real-time system that lets users control their computer cursors using simple hand gestures. The system facilitates an easy operation for us in terms of the use of a cursor by using techniques and hand mark detections. The …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 1, 2026 · pp. 24–35 Read article
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Innovations in Gene Therapy: Revolutionizing Treatment for Genetic Disorders and Diseases
Abstract: Gene therapy is a revolutionary intervention in the treatment of genetic diseases since it is an intervention that aims at the very source of diseases, through editing and modification of genes. More recent innovations in gene editing systems, such as CRISPR-Cas9, CRISPR-Cas12, and prime editing, have greatly increased the accuracy and effectiveness of gene therapies, enabling more specific therapies. The opportunities of personalized medicine are also extended by the creation …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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AI-Driven Topology Optimization of Woven Fiber-Reinforced Composite Chassis Structures for Electric Vehicles Under Crash Loading
Abstract: The structural design of an electric vehicle (EV) chassis represents a unique engineering challenge to achieve minimal weight while meeting occupants' safety requirements during high-energy crash conditions without compromise to the battery housing's integrity or the geometrical constraints of the electric powertrain package. In this paper, a single framework is proposed to integrate physics-based artificial intelligence (AI) surrogate models using PINNs, CNN-accelerated topology optimization, and FEA to design woven fiber-reinforced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 72–89 Read article
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Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article