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261 articles for “Derivative function”
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Influence of Aeration on Biomass and Polyhydroxyalkanoate Accumulation in Priestia flexa JP1: A Foundation for Nano-Biomaterial Development
Abstract: Polyhydroxyalkanoates (PHAs) are microbial polymers that have attracted substantial interest in recent times due to their use as biodegradable substitutes for petroleum-derived plastics and also as precursors for nano-enabled biomaterials. The aim of the present work was to evaluate the effect of static and shaking culture conditions on growth kinetics, biomass formation, and PHA synthesis by Priestia flexa JP1. The bacterial strain was cultured in mineral salt media (MSM) at …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 · pp. 42–50 Read article
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Synthesis, spectroscopic, crystal structure, Hirshfeld surface, computational, and biological investigations on Isophorone derivatives: 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one
Abstract: FT-IR, 1H NMR, and 13C NMR spectroscopy were among the spectroscopic methods used to synthesize and analyze 3-(3,4-dimethoxystyryl)-5,5-dimethylcyclohex-2-en-1-one, a new isophorone derivative. Single-crystal X-ray diffraction (SCXRD) was used to determine the crystal structure, which showed that the molecule crystallizes in a monoclinic system (space group P121/c1) with packing configurations and intermolecular interactions. To learn more about the non-covalent interactions influencing the crystal packing, Hirshfeld surface analysis was used. In order …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 51–69 Read article
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Genetic Algorithm Application for Efficient Load Frequency Control
Abstract: Load frequency control (LFC) is known to be significant control strategy for operation in electric power grid that entails balancing the electrical power provided by power plants with the electrical power consumed by the load. The primary purpose of LFC is to ensure that the power system functions within a specific frequency range and that the power provided by power plants matches the power used by the load. Power system …
Published in Journal of Control & Instrumentation · Vol. 14, Issue 3, 2023 · pp. 1–14 Read article
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Assessing Urban Surface Runoff Management Using the SWAT Model, GIS, and the Rational Method: A Case Study of Karapakkam
Abstract: Urban surface runoff management encompasses strategies aimed at regulating rainwater flow, reducing urban flooding, enhancing groundwater recharge, and contributing to disaster risk mitigation for sustainable urban development. This study seeks to optimize surface runoff management in urban settings by using the soil and water assessment tool (SWAT) model integrated with geographic information systems (GIS) to minimize flood risks. The research focuses on the peak runoff in Karapakkam, a locality within …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 4, Issue 1, 2026 · pp. 37–48 Read article
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New Methods for the Prediction of Multiphase Flow through Wellhead Choke in Gas-Condensate Reservoirs
Abstract: Abstract The wellhead chokes are installed in order to stabilize oil and gas flow rates in production and operation disciplines. Most of the existing empirically derived correlations and predictive models to estimate choke performance have been proposed for oil fields production and operational conditions, and particularly production systems and reservoirs involved with condensation of the gaseous phase still suffer from a detailed consideration on the development of reliable predictive models. …
Published in Journal of Offshore Structure and Technology · Vol. 4, Issue 1, 2017 · pp. 1–10 Read article
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Isolation and Characterization of Natural Honey Yeast Strain : A Review
Abstract: Honey is a natural product rich in sugars, enzymes, and microorganisms, including yeasts, which play a key role in the fermentation processes that occur in honey. These yeasts are of interest due to their potential in biotechnology, fermentation, and health applications. This review discusses the methodologies used to isolate yeast strains from honey, their biochemical and molecular characterization, and their possible applications in industries such as food, pharmaceuticals, and biotechnology. …
Published in International Journal of Insects · Vol. 2, Issue 2, 2025 Read article
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DC Motor Control using Deep Reinforcement Learning for Enhanced Robustness and Precision
Abstract: DC motors remain the workhorse of industrial automation and mobile robotics, but achieving simultaneous high-speed transient response and negligible steady-state error under variable load conditions continues to challenge classical Proportional-Integral-Derivative (PID) controllers. These model-dependent systems often require extensive tuning and struggle to maintain optimal performance when confronted with parametric uncertainties, non-linear friction, or sudden voltage fluctuations. This study presents a novel, model-free control paradigm utilizing Deep Reinforcement Learning (DRL)—specifically, a …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 3, Issue 2, 2025 · pp. 22–29 Read article
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An Integrated Approach towards Diarrhoea
Abstract: Diarrhoea is both a local and a global concern. Diarrhoea is an important problem among the under-five children in India. Illness can range from mild to life-threatening epidemics. Diarrhoea is the frequent passing of loose or watery stools. Clinically, diarrhoea may result from disturbed bowel function, in which following may be the cause: impaired intestinal absorption, excessive intestinal secretion of water and electrolytes, or a rapid bowel transit. Diarrhoeal disorders …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 1, Issue 1-3, 2012 · pp. 19–41 Read article
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Physical Activation Process and Characterization of Bioactive Carbon, with a Focus on its Applications
Abstract: Activated carbon is a form of carbon that has been processed to enhance its surface area and porosity. This processing enables it to function as an efficient adsorbent, attracting and retaining other molecules on its surface. In our environment, many types of biomass waste are inexpensive and renewable. Recently, there has been a growing interest in producing products from renewable resources. A prime example is the use of biomass to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 507–517 Read article
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Clinical Utility of Electroglottography and Videostroboscopy: A Correlational Study
Abstract: Voice serves as a unique identity of an individual which is derived from laryngeal features. Any deviance in the voice quality is considered abnormal and thus seeks clinical attention. Speech-Language Pathologist (SLP) plays an important role in the assessment and diagnosis of voice-related disorders. Although perceptual evaluation is a gold standard, objective methods augment the accuracy of the diagnosis of voice disorders. Electroglottography (EGG) is one such commonly used non-invasive …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 3, 2019 · pp. 1–10 Read article
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Concept of Hemiplegia (Falij-e-Nisfi) in Unani System of Medicine: A Comprehensive Review
Abstract: Falij is derived from an Arabic word Falj which literally means splitting into halves. It is the paralysis of a longitudinal half of the body starting either below the neck, sparing head & face or covering the entire longitudinal half of the body from head to toe. It is analogous with Hemiplegia occurring due to stroke. There are almost 4.7 million stroke survivors in the United States, and approximately 780,000 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 2, 2019 · pp. 37–41 Read article
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Recent Advancements in Nanobiocomposite-Based Wound Healing and Tissue Regeneration
Abstract: Haemostasis, inflammation, proliferation, remodeling, and other highly coordinated cellular and molecular activities are all part of the complex biological processes of wound healing and tissue regeneration. Following an injury, these stages cooperate to restore tissue integrity and function. However, this normal process is disturbed in many clinical circumstances, especially chronic wounds such diabetic ulcers, burns, and pressure sores. Prolonged inflammation, chronic microbial infection, diminished angiogenesis, and impaired extracellular matrix production …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–318 Read article
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Adaptive Reuse of Abandoned Industrial Structures for Healthcare Centres
Abstract: Adaptive reuse as an industry has been marketed as an expensive one. When it comes to the retail, hospitality, or domestic sectors, that is the case; however, the use of abandoned structures has been found to be cost-effective in the healthcare sector. This research paper aims to understand adaptive reuse in the context of the healthcare industry. It is a well-known fact that the worldwide epidemic drove the economy to …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 1, 2024 · pp. 01–08 Read article
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Aspergillus Oryzae: Multifunctional Powerhouse Revolutionizing Food Industries and Gut Health
Abstract: Aspergillus oryzae, commonly known as “Koji mold,” is a filamentous fungus extensively utilized in various food industries due to its robust enzymatic activity and generally recognized as safe (GRAS) status. This review explores its diverse applications, focusing on its role in fermented food production, enzyme generation, and contributions to gut health. In the production of fermented foods, such as soy sauce, miso, and sake, A. oryzae serves as a crucial …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Thermo-mechanical Analysis of Orthotropic plate under Sinusoidally Distributed Thermal load by using Trigonometric shear Deformation Theory (TSDT)
Abstract: For the thermal analysis of simply supported square and rectangular plates applied to sinusoidaldistributed linear thermal load throughout the plate thickness and in combination with sinusoidaldistributed transverse mechanical loading, a trigonometric shear deformation theory is proposed. Inthis work, a sinusoidal function in terms of thickness coordinates is being used in the displacement fieldin conjunction with the transverse shear deformation effect. The normal and shear stress can bedetermined by using the …
Published in Journal of Experimental & Applied Mechanics · Vol. 12, Issue 3, 2021 · pp. 10–33 Read article
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High-Performance Liquid Chromatographic Assay of Nateglinide and its Stability Study
Abstract: Nateglinide (NTG) is a D-phenylalanine derivative used in the treatment of type-2 diabetes mellitus. An accurate, sensitive and reproducible high-performance liquid chromatographic (HPLC) method has been developed and validated for the quantification of NTG in pharmaceutical samples. The drug was eluted from Inertsil ODS 3V (150×4.6 mm; 5 µm particle size) column at 30á´¼C with a mobile phase consisting of phosphate buffer of pH 3.3 and methanol (70:30 v/v). The …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 41–52 Read article
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Intuitionistic Fuzzy Hypergraph Laplacians and Dominating Transversals for Resilient Discrete Network Design
Abstract: This manuscript develops a discrete mathematical framework for resilience analysis on networks whose interactions are polyadic, uncertain, and partially conflicting. Classical graphs compress multi-way coordination into pairwise edges, while ordinary fuzzy graphs often ignore the non-membership information that becomes critical in emergency logistics, infrastructure interdependence, and cyberphysical coordination. We therefore formulate an intuitionistic fuzzy hypergraph in which each vertex hyperedge incidence carries membership, non-membership, and hesitation, and we construct a …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 2, 2026 · pp. 15–21 Read article
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SIMULATION OF THE PERFORMANCE OF PV/T (PV-PCM) SYSTEMS IN TRANSIENT STATE
Abstract: The paper describes the analysis of the thermal performance of a PCM unit attached to a PV panel configuring a PV/T system. Thermal performance has been analyzed from the transient process point of view considering the temperature evolution of the PCM with time dependent on ambient temperature and solar radiation. A specific algorithm for determining the time evolution of the PCM temperature has been developed. The model uses the DERIVE …
Published in Journal of Thermal Engineering and Applications · Vol. 10, Issue 1, 2023 · pp. 1–13 Read article