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387 articles for “isolated”
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Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
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Synthesis, Characterization, and Reactivity of Bivalent Tin(II) with 4-Tert-butylphenol
Abstract: Bivalent tin(II)-4-tert. butylphenoxide of composition Sn(OC6H4X-4)2(I), where X = But, has been synthesized by the reaction of stannous chloride (SnCl2) with bimolar amounts of 4-tert. butyl phenol (HOC6H4But-4) in the presence of the base, diethyl amine, in tetrahydrofuran (THF) solvent. The resulting complex was characterized by elemental analysis, molecular weight determination, molar conductance measurement, IR, and 1H NMR spectral studies. The reactivity of the newly synthesized complex (I) with HgCl2 …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 14–19 Read article
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A Split and Merge UNet: A Deep Learning Assisted UNet Model to Segment Corpus Callosum of Brain for Automatic Autism Detection
Abstract: In recent years, deep learning techniques have shown remarkable performance in various image analysis applications, particularly in the domain of medical image processing. Among these, image segmentation plays a critical role, as it helps in isolating and analyzing specific regions within medical images. The proposed study focuses on segmenting the corpus callosum, a vital structure in the human brain, using a novel optimization technique known as the Split and Merge …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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A Review on Phytochemistry and Pharmacology of Macaranga peltata
Abstract: Macaranga peltata, categorized within the Euphorbiaceae family, represents a prevalent pioneer arboreal species across Southeast Asia, specifically in regions such as India and Sri Lanka. This review scrutinizes the phytochemical properties and pharmacological profiles of Macaranga peltata, underscoring both its historical medicinal applications and prospective therapeutic roles. The plant exhibits a rich composition of secondary metabolites, encompassing flavonoids, stilbenes, tannins, and terpenes, with the majority of these compounds being extracted …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 50–59 Read article
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Performance Optimization of Photovoltaic-thermal (PVT) Systems: A Comprehensive Review of Design and Efficiency Enhancements
Abstract: The desire for renewable energy solutions and the rising demand for energy worldwide have driven important developments in hybrid photovoltaic-thermal systems. Photovoltaic-thermal systems provide the advantages of both thermal energy collection and electrical energy generation as they integrate photovoltaic and thermal collectors into a single module. However, a number of variables, including system architecture, material choice, cooling systems, and ambient circumstances, affect how well they function. The goal of this …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 11, Issue 2, 2024 · pp. 9–16 Read article
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Sign Language and Face Expression Recognition Using Neural Networks: Deep Learning Approach to Break Communication Barriers
Abstract: Our study proposes a multimodal gesture recognition system specifically designed to aid communication for the deaf community. By employing neural network concepts, we utilize 3D convolutional neural networks (3D CNNs) to extract features from both hand and face images, focusing on relevant regions. Preprocessing techniques are applied to isolate these areas of interest prior to feature extraction. Unique 3D CNN architectures are then trained for each modality to capture the …
Published in Current Trends in Signal Processing · Vol. 14, Issue 3, 2024 · pp. 1–10 Read article
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Sustainable Learning and Education
Abstract: Sustainable learning asnd education are approaches to learning that prioritize environmental stewardship, social equity, and economic prosperity. A comprehensive approach to education, sustainable learning and education acknowledges the interdependence of social, economic, and environmental systems. Rather than treating these aspects in isolation, sustainable education integrates them to foster a comprehensive understanding of sustainability issues. Sustainable education places a strong emphasis on systems thinking, which entails comprehending the feedback loops and …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 15–19 Read article
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Encapsulation of Karela Extract in Polymer Nanoparticles
Abstract: Karela (Momordica charantia) fruit extract possesses promising antibacterial properties. However, its direct application can be limited by factors like degradation and uncontrolled release. This study explores the encapsulation of Karela extract within biocompatible and biodegradable polymeric nanoparticles as a potential strategy to enhance its efficacy. The research investigates the development of nanoparticle systems using various polymers and their impact on the stability, controlled release, and antibacterial activity of the encapsulated …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 864–867 Read article
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Diglycidyl Ether of Bisphenol A (DGEBA) Based Epoxy Sizing Agent Induces Surface Polarity in Carbon Fibers†
Abstract: Determination of the chemical structure and composition of the sizing agent is a challenge as its concentration is low, varying in the range from ~0.5 wt.% (for polyacrylonitrile, PAN, based carbon fibers) to ~1 wt.% (for pitch-based carbon fibers). Moreover, such a piece of knowledge is vital for designing compatible polymer matrices to prepare CFRPs for diverse applications. As a result, the sizing layer that is coated on the carbon …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 24–34 Read article
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Effect of Particle Size Mix Ratio of Clay and Agro-Based Material for AGO and PMS Treatment on Microbial Growth
Abstract: The characteristics of possible microbes isolated and identified on adsorption process involving AGO and PMS as contaminants in fresh water medium was monitored using agro – based materials. The formulated adsorbent is made of clay with ago-based materials of Banana Ogoni Red (BOR) Banana Native (BN), Plantain Agbagba 1 (PA1), and Plantain Ogoni Red (POR). The particle size mixed ratio of clay to the various agro-based materials were 150𝜇𝑚 R5:5, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 2, 2024 · pp. 05–14 Read article
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SpecialMinds: Learning App for Visually Impaired Students
Abstract: This research aims to identify the challenges and barriers that visually impaired students encounter in the educational environment, with a focus on adaptive strategies and innovative solutions. Visually impaired students often experience difficulties in listening, speaking, reading, writing, conceptual understanding, and social communication. As one of the most excluded and discriminated groups in society, these students may feel isolated, which further impacts their learning. Given the significance of quality education …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 1, 2025 · pp. 11–23 Read article
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Exploring the Effectiveness of IoT in Virtual Doctor Robot Systems
Abstract: The design and development of a Virtual Doctor Robot (VDR) using Internet of Things technology is presented in this study with the goal of facilitating remote medical assistance. In light of the constraints associated with physical presence, especially in underprivileged areas like isolated parts of India during the COVID-19 pandemic, videoconferencing (VDR) is a viable means of bridging the gap between patients and physicians. The VDR makes accurate diagnostic and …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 3, 2024 · pp. 13–23 Read article
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Unlocking Microbial Potential: Innovations in Natural Product Biosynthesis and Therapeutic Applications
Abstract: MNPs play a pivotal role in diverse fields, spanning medicine, agriculture, and industry. This review paper synthesizes insights from various discussions on microbial natural products, encompassing their sources, bioactive properties, and applications. We explore microbial diversity contributing to natural product synthesis, emphasizing bacteria and fungi as prolific producers. The methods for isolating and characterizing these compounds underscore the interdisciplinary nature of microbial natural product research utilizing various analytical techniques contributing …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 18–38 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Analysis of Steel Chip Fiber Reinforced Composite Dual Pile Under Lateral Load Conditions on Sloping Terrain
Abstract: Pile foundations, in addition to supporting vertical loads from superstructures, are subjected to lateral stresses arising from seismic activities, wind gusts, water currents, and traffic impacts etc. Failure to account for these lateral forces can pose significant risks if the structure is expected to encounter any form of lateral pressure. Previous research has investigated the behavior of individual composite piles under horizontal forces, considering different soil properties, to determine the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 210–220 Read article
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Investigating the effect of Anodes workfunction on the Opto-electronics Performance of Organic Light Emitting Diode
Abstract: The research aims to assess the performance of organic light-emitting diodes (OLEDs) by exploring how various anode materials affect their optoelectronic properties. OLEDs are crucial for modern displays and lighting, and their efficiency and functionality are heavily influenced by the materials used in their design.This study examines four different anode materials: Indium Tin Oxide (ITO), Zinc Oxide (ZnO), Aluminum-doped Zinc Oxide (AZO), and Poly(3,4-ethylenedioxythiophene) Polystyrene Sulfonate (PEDOT: PSS). These materials …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 2, 2024 · pp. 27–37 Read article
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Influence of Social Media on Anxiety, Depression, and Loneliness: A Review
Abstract: Social media is a daily tool for communication, entertainment, and information exchange for millions of individuals worldwide. However, worries regarding its possible detrimental effects on mental health have surfaced, especially about despair, anxiety, and loneliness. This study's goal was to examine the connection between mental health issues and social media use. It highlights the clear connection between elevated psychological discomfort—such as anxiety, depression symptoms, loneliness, and overuse of social media—and …
Published in Recent Trends in Social Studies · Vol. 2, Issue 1, 2025 · pp. 22–27 Read article
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Design of Integrated DC/DC Converter Topology for Hybrid Vehicle
Abstract: Hybrid vehicles traditionally rely on separate DC/DC converters for both the battery and fuel cell, which often leads to increased size, higher costs, energy losses, and limited performance. This paper presents an improved solution: a compact, integrated DC/DC converter with a non-isolated, multi-port design. This new approach simplifies the system by combining the fuel cell and battery into a single, unified converter, reducing the typical drawbacks of conventional designs. The …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 1, 2025 · pp. 25–31 Read article
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POTENTIAL BIOPRESERVATIVE EFFECT OF ANTIMICROBIAL PEPTIDES OF SEEDS OF Vigna unguiculata (Cow Pea) ON Hibiscus sabdariffa L. (Roselle) Calyces (Zobo) DRINK
Abstract: Natural and efficient food preservatives are in greater demand because of growing concerns about the safety and quality of processed beverages. Antimicrobial peptides have emerged as promising natural substitutes for synthetic preservatives, boasting advantages like wide-ranging activity and reduced toxicity. In this research, we investigate the inhibitory effects of these peptides against common spoilage microorganisms in 'Zobo' drink. Peptides were extracted and purified from germinated Vigna unguiculata) seeds harvested on …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 26–41 Read article
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Risk Management in Civil Engineering by FTA, FMEA and Risk Matrix
Abstract: Infrastructure projects, particularly in civil engineering, are fraught with uncertainties that manifest as both physical and financial risks. The project report, titled Quantifying and Managing Financial and Physical Risks in Infrastructure Projects, aims to bridge the existing gap between managing these two critical categories of risks. By integrating advanced statistical methodologies such as Failure Mode and Effects Analysis (FMEA), Fault Tree Analysis (FTA), Risk Matrix, and Regression Analysis, this study …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 34–46 Read article