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445 articles for “future directions”
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Navigating the Antenna Frontier for Emerging IoT Technologies
Abstract: Internet of Things (IoT) is rapidly transitioning from niche applications to a pervasive, interconnected fabric of intelligent devices, demanding unprecedented levels of performance, reliability, and miniaturization from its constituent components. At the heart of this revolution lies the antenna, the crucial interface between the digital and physical realms. This paper delves into the intricate and evolving landscape of IoT antenna design, specifically addressing the unique challenges and opportunities presented by …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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A Brief Review on Interfaces of Copper Welded to Different Materials
Abstract: In engineering applications, three metals with high conductivity are primarily used such as copper (Cu), aluminium (Al), and silver (Ag). Each has its unique set of properties that affect specific engineering applications. Infact the choice of conductor depends on a mixture of cost, technical parameters, and environmental conditions. Among these, Copper is widely valued in engineering applications due to its antimicrobial property, excellent electrical (about 100% IACS) and thermal conductivity, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 25–36 Read article
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Greener 3D Printing: The Role of Artificial Intelligence in Sustainable Polymer and Composite Manufacturing
Abstract: The integration of sustainable materials with additive manufacturing (AM) technologies marks a significant step towards environmentally responsible production. Biodegradable polymers, recycled thermoplastics, and bio-based composites, when used in 3D printing, offer the potential to reduce the ecological footprint of manufacturing. However optimizing the interplay between material properties process parameters, and product performance remains a complex challenge. This review examines how artificial intelligence (AI) is being applied to address these challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 288–300 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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A Comprehensive Review on Federated Learning in Disease Detection
Abstract: Healthcare data, which is frequently dispersed among various organisations, has enormous potential to improve predictive analytics and illness identification. However, there are substantial privacy & legal obstacles to sharing this private data for centralised model training. Federated Learning is a paradigm shift that allows several organisations to work together to build a global model without disclosing raw patient information. Federated Learning uses a larger dataset to provide more reliable insights …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–21 Read article
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Engineering Polymer Innovations for Improved Battery Safety and Vehicle Efficiency: A Comprehensive Review
Abstract: Electric vehicles (EVs) are high-power systems that require high-quality materials to ensure safety, reliability, and performance under extreme operating conditions. Polymer materials have become critical engineering materials in meeting these requirements due to their lightweight nature, design flexibility, durability, and high electrical insulation capability. Consequently, polymers are widely used in key EV components, including battery enclosures, module frames, thermal interface materials, wiring insulation, and lightweight structural parts.Recent developments in polymer …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 500–512 Read article
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Nano‑Enabled CT for Cancer Imaging: From Molecular Targeting to Image‑Guided Therapy
Abstract: Nano‑enabled computed tomography (CT) exploits high‑atomic‑number (high‑Z) nanomaterials engineered with targeting ligands and therapeutic payloads to enhance contrast, enable molecular imaging, and support image‑guided interventions in oncology. Tumor‑specific nanoprobes such as RGD‑modified gold nanorods, polymer‑coated bismuth nanoparticles, and peptide, antibody, or aptamer‑functionalized platforms can intensify tumor conspicuity, allow early lesion detection and staging, and provide real‑time treatment monitoring. Integration of CT visibility with photothermal, photodynamic, chemo‑, radio‑, and immunotherapeutic functions …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 40–49 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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Polymer Electrolytes for Flexible Energy Storage
Abstract: The research explores polymer electrolytes as promising materials for flexible energy storage applications, driven by the growing demand for wearable and portable electronics. Polymer electrolytes, including solid, gel, and composite types, offer key advantages such as mechanical flexibility, lightweight design, and improved safety over traditional liquid electrolytes. This study reviews recent developments in materials like polyethylene oxide (PEO), polyvinylidene fluoride (PVDF), and ionic liquid-based systems, focusing on their ionic conductivity, …
Published in International Journal of Advance in Molecular Engineering · Vol. 4, Issue 1, 2026 · pp. 27–35 Read article
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Transplanting Hope: Organ Transplantation’s Science and Humanity
Abstract: One of the most revolutionary developments in contemporary medicine is organ transplantation, which provides patients with end-stage organ failure with both life-saving and life-improving options. The science and humanity of organ transplantation are examined in this article, which also looks at the ethical, social, and emotional factors that influence the area as well as the medical concepts that make transplants successful. It examines the biological underpinnings of immunosuppression and organ …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 36–41 Read article
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Open Source Software Empowering Artificial Intelligence, Machine Learning, and Cyber Security: A Comprehensive Research Study
Abstract: Open Source Software (OSS) has become a foundational pillar for rapid innovation across Artificial Intelligence (AI), Machine Learning (ML), and Cybersecurity. This paper delivers a comprehensive, journal-length analysis of OSS-driven ecosystems, emphasizing collaborative development, transparency, and accelerated deployment. By providing freely available libraries, tools, and frameworks, OSS makes it easier for developers and researchers to experiment, build models, and deploy solutions quickly. This study examines how OSS can be combined …
Published in Journal of Open Source Developments · Vol. 13, Issue 1, 2026 Read article
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Comparative Assessment of Polymers and Composites for Solar Panels: Fundamentals, Performance Metrics, Manufacturing, and Sustainability
Abstract: This paper presents a comprehensive review of the main types of Photo Voltaic polymers and composites such as crystalline silicon (both mono- and poly-Si), thin-film tech (CdTe, CIGS, a-Si), perovskites, and organic/dye-sensitized cells and analyses the parameters such as efficiency, fill factor, open-circuit voltage, temperature response, and degradation. The analysis focusses on polymers and composites and manufacturing techniques like vapor deposition, roll-to-roll printing, and both solution and vapor techniques for …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 120–130 Read article
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Fracture Analysis of Laminated composite plates using Extended Finite Element Method: A Review
Abstract: Laminated composite plates are used in aerospace, automotive, and marine industries. They feature great durability against fatigue, a high strength-to-weight ratio, and mechanical attributes that may be altered. However, they are prone to fracture and delamination under complex loading, requiring accurate fracture analysis for structural integrity. Traditional finite element methods (FEM) need extensive mesh refinement for modelling crack propagation which increases the computational costs. The Extended Finite Element Method (XFEM) …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 16–25 Read article
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Intelligent Power Quality Enhancement Strategies for PV-Integrated Smart Distribution Networks: A State-of-the-Art Review
Abstract: The rapid integration of photovoltaic (PV) systems into modern power distribution networks has introduced significant challenges related to power quality. Issues such as voltage fluctuations, harmonic distortion, flicker, and reactive power imbalance arise due to the intermittent and nonlinear nature of solar energy generation. This paper presents a concise literature review of various power quality enhancement techniques employed in PV-integrated networks. Key approaches include the use of active power filters …
Published in International Journal of Electrical Power and Machine Systems · Vol. 4, Issue 1, 2026 · pp. 30–53 Read article
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Improving Dataset Integrity Through Automated Data Cleaning Techniques
Abstract: High-quality data is a fundamental requirement in data science for producing trustworthy analytical insights and effective machine learning models. Problems, including incomplete records, inconsistent entries, duplicate observations, and anomalous values, can severely reduce the accuracy and robustness of predictive systems. As modern datasets continue to expand in both volume and structural complexity, relying on manual data cleaning methods become time-consuming and error-prone, highlighting the growing importance of automated data preprocessing …
Published in International Journal of Data Structure Studies · Vol. 4, Issue 1, 2026 · pp. 40–45 Read article