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618 articles for “Drug–protein interactions (DPIs)”
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“DEVELOPMENT AND CHARACTERIZATION OF PHYTOSOMES FOR THE TREATMENT OF ANTI-CANCER ACTIVITY BY USING THE Spirulina (Arthospira Plantesis) EXTRACT”
Abstract: This study aims to investigate and evaluate spirulina's anticancer properties.The current research is centred on obtaining a Spirulina-containing drug. The goal is to design and create Phytosomes, characterizing them based on relevant and crucial parameters. The process of solvent evaporation was utilized in the creation of Phytosomes. Various parameters such as zeta potential, particle size, infra-red spectral analysis, % drug content, encapsulation efficiency, and % drug release (% DR) were …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 10–22 Read article
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Rheumatoid Arthritis and its Relationship with Vitamin D, ESR, and Obesity
Abstract: Recent years have seen a rise in the prevalence of rheumatoid arthritis (RA), a disease marked by the destruction of articular cartilage and ankylosis of the joints, as well as other complications such as diffuse lung inflammation, sclera, pleura, pericardium, and nodular lesions, which are also common in subcutaneous tissue. Reviewing RA symptoms, diagnosis, treatment, and associations with vitamin D, ESR, and obesity was the aim of the study. Even …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 06–12 Read article
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Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
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Review on Spirulina ( Green Alage)
Abstract: Spirulina is an edible blue-green algae that is a plant protein source. In recent years, its health benefits have attracted scientific attention, including micro-level examinations of the algae's bioactive components. As proof of concept, investigations conducted in vitro, in vivo, and ex vivo have shown how spirulina works and how it affects immunity. Spirulina has been used as a whole food and as a nutritional supplement for many years. It …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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User Centric Design: A Framework for Transforming Design Studios into Smart Workspaces
Abstract: In contemporary design studios, the integration of smart technologies has become imperative to enhance productivity, collaboration, and creativity among designers. This research paper presents a comprehensive framework for the transformation of conventional design studios into smart workspaces, focusing on user-centric design principles. The concept of User-Centric Design emphasizes its departure from traditional design approaches by placing the user experience at the forefront of the creative process. It highlights the increasing …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 1–13 Read article
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Recent Applications and Influences of Artificial Intelligence (AI) In Chemical and Allied Sciences
Abstract: Artificial Intelligence (AI), the future tool of mankind that can revolutionise scientific research by making it faster, add more efficiently and accurately. During the pandemic situation, the scientific community was parted into two distinct groups, the computation-dependent community could easily continue their research work from their resident, while the works of the other group of researchers with lab-oriented research stopped entirely. In this connection use of AI becomes important and …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 22–48 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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Harmonizing Foam and Function: Clubhouse Design in Apartment Complexes
Abstract: The increasing demand for urban living has led to the proliferation of apartment complexes, where common spaces like clubhouses play a pivotal role in fostering community and enhancing residents' quality of life. However, many existing clubhouses fail to harmonize form (aesthetic design) and function (practical usability), resulting in spaces that are visually appealing but underutilized or, conversely, highly functional but lacking in ambiance. This research addresses the critical issue of …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 2, 2024 · pp. 38–57 Read article
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Multidimensional Impacts on Bryophyllum Pinnatum for the Potential of Obesity: A Review
Abstract: Global public health concerns related to obesity are growing. Several comorbid illnesses, including cardiovascular disease (CVC), gastrointestinal disorders, type 2 diabetes (T2d), joint and muscle disorders, respiratory difficulties, and psychological disorders, are significantly more common in obese patients. The widespread misconception that obesity stems solely from a lack of self-control is gradually losing its stigma as awareness about fat-related issues grows. Instead of synthetic drugs herbal or medicinal plants are …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 42–51 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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Atmospheric Modeling: A Comprehensive Review of Numerical Approaches and Applications
Abstract: Atmospheric modeling plays a crucial role in understanding and predicting atmospheric processes, weather patterns, and climate variability. This review synthesizes current methodologies and applications across several types of atmospheric models, including numerical weather prediction (NWP), climate models, air quality models, and chemical transport models. We explore the intricacies of data assimilation, model evaluation, parameterization, and the importance of high-performance computing in advancing model accuracy and efficiency. Special emphasis is placed …
Published in International Journal of Atmosphere · Vol. 1, Issue 2, 2024 · pp. 16–21 Read article
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Gesture-Based Cursor Control: A Comprehensive Review of Techniques and Applications
Abstract: Although hand gesture detection for man-machine interfaces has advanced recently, many systems still have issues with background and lighting. We have developed a rapid motion history image-based system to categorize dynamic hand motions and a face detection method to adaptively detect skin color. For the up, down, left-, and right-hand gesture classifiers, four sets of haar-like directional patterns were trained. To operate different household appliances, six hand gestures were defined, …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 1, 2025 · pp. 9–13 Read article
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Human-robot Collaboration in Manufacturing: Safety, Efficiency, and Technological Developments
Abstract: Human-robot collaboration (HRC) has emerged as a transformative force in modern manufacturing, significantly enhancing productivity, operational flexibility, and overall efficiency. This review article explores the fundamental aspects of HRC, with a particular focus on safety protocols, efficiency optimization, and technological advancements that are shaping the future of collaborative robotics. Ensuring safety in HRC environments is a primary concern, necessitating the implementation of advanced safety measures, risk assessment methodologies, and compliance …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 3, Issue 1, 2025 · pp. 18–23 Read article
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Exploring Carbon Nanotubes in Nanotechnology: Functional Properties, Surface Modifications, and Biomedical Innovations
Abstract: Significant progress has been made in nanotechnology in recent years, especially in the creation of sensors with a broad range of uses. Among these, carbon nanotubes (CNTs) are cylindrical structures composed of carbon, with diameters in the nanometer range. CNTs originate from graphite sheets, where the graphite layers resemble a rolled-up, continuous, and robust hexagonal mesh. These hexagons have carbon atoms at their vertices. The fabrication of CNTs typically involves …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 24–31 Read article
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Iron Oxide/Chitosan Nanocomposite: Properties and Design for AI Enhanced Immunotherapy and Regenerative Medicine
Abstract: Biopolymers are valuable complex materials. They attract attentions of many scientists, engineers, and medical professionals’ due to their distinguished properties for various applications. In this research, emphasis is given to Fe3O4/Chitosan nanocomposite which has desirable biophysical properties compared to pure Chitosan nanoparticles. Following the green synthesis procedures and characterization methods including thermo gravimetric analysis, AI assisted biomedical application of; Fe3O4/Chitosan nanocomposite is presented. The effect of alkali typically, KOH, in …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 22–32 Read article
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A Literature Survey on Biological Activities of Thiazolidine Derivatives
Abstract: Hetercyclic compounds play a vital role in both chemical and life sciences. Among them ,thiazolidinone represent a significant class, characterized by a five- membered saturated ring containing both sulfur and nitrogen atoms. Structurally, thiazolidinones are derived from thiazole, with sulfur position at the 1-position, nitrogen at the 3-position , and a carbonyl group typically located at the 2-, 4-, or 5- position are possible, though structural and functional diversity is …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 16–21 Read article
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Temporal Shifts in Forage Quality: Stage of Maturity, Biomass Yield, Performance Matrix, and Ecosystem Responses
Abstract: Forage quality is a key determinant of livestock productivity and environmental sustainability, with its dynamics closely linked to the stage of maturity, biomass yield, and broader ecosystem interactions. This study explores the temporal shifts in forage quality throughout its growth cycle, emphasizing the effects of maturity on nutrient composition, digestibility, and overall biomass yield. The relationship between these factors and their impact on animal performance, including milk yield, growth, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article
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Immunological Biomarkers and Epidemiological Evaluation of Lymphatic Filariasis Elimination Efforts in Osun State, Nigeria
Abstract: Lymphatic filariasis (LF) remains a neglected tropical disease affecting millions globally, despite extensive elimination efforts. While the interruption of transmission is a key goal, the long-term immunological effects on individuals with existing complications like elephantiasis remain poorly understood. This study assessed the current transmission status of LF and the haematological profiles of infected individuals across selected Local Government Areas (LGAs) in Osun State, Nigeria. A total of 7,388 individuals from …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 22–30 Read article