Search
474 articles for “Doses”
-
Effect of Kitchen Waste Compost and Vermi-Compost in Combination with Chemical Fertilizer on the Production of Tomato
Abstract: An experiment was carried out to develop standard production method of winter tomato under Good Agricultural Practices (GAP) and value chain development at the farmer’s field named Mojnu Mia son of Nishan Mondal located at Char dudiagacha, Adarvita, Madarganj, Jamalpur, Bangladesh with the assistance of HELVETAS, Swiss Inter Cooperation, Bangladesh, Jamalpur during November 2015 to April 2016. BARI Tomato-14 was used in the study. Eight treatments were constructed with the …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 3, 2017 · pp. 15–24 Read article
-
Effect of Short-term Exposure of Agrochemical Constituents (Nitrate, Nitrite, Phosphate and Potassium) on Survival of Fingerlings of Guppy Fish, Poecilia reticulata
Abstract: Increased use of agrochemicals enhances eutrophication and thereby inducing hypoxic condition which adversely affects aquatic flora and fauna. Present study was aimed to investigate the effects of short-term exposure of different concentration of nitrate (NO3), nitrite (NO2), phosphate (PO4) and potassium (K) on survival of Guppy fish, Poecilia reticulata. Fingerlings of Poecilia reticulata were exposed to increasing concentration (1, 10, 100, 1,000 and 10,000 mg/L) of NO3, NO2, PO4 andK …
Published in Research & Reviews : Journal of Ecology · Vol. 11, Issue 2, 2022 · pp. 1–9 Read article
-
Neutralization of Inflammatory Effect of LPS by Premna latifolia Extract in RAW 264.7 Cells
Abstract: Natural compounds of Premna latifolia, extracted using petroleum ether, ethyl acetate and methanol as solvent has dose-dependent effect against inflammatory effect of lipopolysaccharide (LPS) in RAW 264.7 cells. Keywords: Premna latifolia, inflammation, petroleum ether, ethyl acetate, methanolCite this ArticleDevi A. Neutralization of inflammatory effect of LPS by Premna latifolia extract in RAW 264.7 cells. Research & Reviews: Journal of Herbal Science. 2018; 7(3): 1–3p.
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 3, 2018 · pp. 1–3 Read article
-
Current Prospective of NLCs in Parkinson’s Disease: An Outlook
Abstract: Parkinson's disease (PD) is 2nd most a neuro-degenerative disorder of the central nervous system affecting 7–10 million people of worldwide as the report of WHO 2014. It occurs due to the death of dopamine-generating cells in the substantia nigra, a region of the midbrain. It is characterized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole Hydrochloride is a drug of choice …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 18–29 Read article
-
Petroleum Ether, A Laboratory Solvent Induced Cannibalism, Piloerection and Straub Tail Reaction in Rodents
Abstract: Petroleum ether is one of the most commonly used solvent in extraction of herbals/biological substances. In pharmacognostical studies, petroleum ether is used as a solvent for extract of herbals which was used for further pharmacological investigation. In a few of their studies, the authors have observed petroleum ether-induced piloerection which may be related to the herbal extract or trace solvent effect. Complete removal of petroleum ether solvent in herbal extract …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 1, Issue 2, 2014 · pp. 6–10 Read article
-
Phytochemical, Acute Toxicity and Heavy Metals Evaluation of Khaya senegalensis (Desr.) A. Juss (Meliaceae) Stem Bark
Abstract: The present work was aimed to determine the phytochemical constituents, median lethal dose (LD50) and levels of heavy metals in Khaya senegalensis stem bark obtained from Kano State, Nigeria. The preliminary phytochemical screening revealed the presence of steroids, terpenoids, alkaloids, anthraquinones, saponins, phenolic compounds and carbohydrates, while the LD50 of the aqueous stem bark extract was above 5000 mg/kg body weight using OECD and Lorke’s method. The heavy metals analysis …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 1, 2020 · pp. 1–7 Read article
-
A Review on Natural Radio-protective Agents
Abstract: AbstractRadioprotectors play crucial role in safeguarding biological system from various damages to DNA (Deoxyribonucleic acid), protein molecules, lipids by peroxidation as well as hematopoietic, gastrointestinal, reproductive and central nervous system exposed to radiation dose especially against radiation injury in cancer survival patients undergoing radiotherapy. As over 40% patients require this therapy, during the treatment where ionizing radiation is used to shrivel tumors and exterminate cancer cells by disrupting their DNA. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 20–31 Read article
-
A Study of New Form of Antitumor Chemotherapeutic Drugs Production
Abstract: Chemotherapy methods that exist today do not permit to act with purpose on a malignant tumor with a pre-calculated shock dose of cytostatic while killing healthy cells of the human body that makes the use of these methods for the treatment of cancer patients not effective. This study presents a new type of antitumor drug obtained by a specially developed method, which is a support material with a uniform distribution …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 6–10 Read article
-
Impact of Grape Seed Extract on Liver Function against Cadmium Chloride-Induced Toxicity
Abstract: The present study was designed to evaluate the antioxidant activities of grape seed and to benefit from the impact of grape seed on hepatotoxicity mediated by cadmium chloride (CdCl2). Gas liquid chromatography (GC-MS) was used to assay the chemical profile. A total of 40 male rats (10 rats per group) were divided into four groups: (1) control group, (2) grape seed group: rats treated with grape seed extract (GSE) at …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 3, 2020 · pp. 30–39 Read article
-
Formulation Development, Characterization and in-vitro Evaluation of Nano-Lipid Carriers of Ropinirole HCl for Persistent Parkinsonian Management
Abstract: According to a report of World Health Organization (WHO) 2014, Parkinson's Disease (PD) is the second-most neurodegenerative dysfunction of the central nervous system (CNS) of human being effecting 7–10 million people worldwide. It is primarily due to the death of dopamine-generating cells in the substantia-nigra of midbrain. It is symptomatized by tremor, rigidity, bradykinesia, dementia, depression and falls or emerges with the progression of the disease. Ropinirole HCl is a …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 14–23 Read article
-
Phytochemical Screening and Nephroprotective Activity of Citrus maximus
Abstract: Several plants with medicinal properties are used to treat diseases. Many people rely on traditional medicines, chiefly plant-based, for their major health care needs. The wide biological and medicinal properties, higher safety margins and affordability, make plant based medicines attractive for use in developing countries for primary health care. Citrus maxima belong to the family of Rutaceae; the phytochemical screening showed the presence of alkaloids, terpenoids, sterols, flavonoids and carbohydrates. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 3, 2019 · pp. 46–56 Read article
-
A Descriptive Study to Assess the Knowledge Attitude, Practice and Concerns Regarding Covid 19 Vaccine and its Information Sources Among General Population of Urban Health Centre of SGRD Hospital, Sri Amritsar
Abstract: The SARS CoV-2 virus, which causes the acute respiratory illness coronavirus disease 2019, was initially discovered in late 2019 in Wuhan, China. The disease then spread quickly throughout the nation, and later the entire world had to suffer and expend extra effort by putting various measures in place to manage and avoid the COVID-19 pandemic. 100 participants were recruited for a descriptive study. Data and a socio-demographic profile were used …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 2, 2023 · pp. 42–51 Read article
-
Biodegradable Polymers Properties and Applications
Abstract: Polymers that can degrade into biologically compatible components under physiologic conditions present a far more attractive alternative for the preparation of drug delivery systems. The use of biodegradable polymers precludes the need for retrieval at the conclusion of the dosing regimen, thereby avoiding the potential complications associated with the use of non-degradable systems. A wide variety of approaches are continuously being pursued in the quest for improved biodegradable drug delivery …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 57–72 Read article
-
An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article
-
Distinctive Approaches for Improving the Aqueous Solubility of BCS Class II Drugs
Abstract: The most difficult feature of many novel chemical entities is their solubility behaviour, as 60 percent of new promising products suffer solubility limitations. This is the most common reason for novel medicine compounds failing to reach the market or performing to their full potential. The proportion of the aqueous phase when the solution is in equilibrium with the pure substance in its normal phase is referred to as aqueous solubility. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 3, 2023 · pp. 52–56 Read article
-
Revealing the Effect of Swift Carbon Ion Beam on Radiation Sensitivity of Radio-frequency Magnetron Sputtered Grown Alumina Thin Films
Abstract: Regarding targeted treatment, hadron therapy is beneficial than conventional radiotherapy based on X rays/gamma rays due to characteristic energy loss profile of energetic charged particle during ion matter interaction. In this regard, dose monitoring and its precise measurement with spatial accuracy are very crucial. Thermoluminescence (TL) based thin film radiation dosimeter has the potential to serve this purpose. In hadron therapy, use of swift carbon ion beam is found to …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 23–29 Read article
-
ADR CAUSED BYANTI-SNAKE VENOM A CASE REPORT HIGHLIGHTING THE PATHOPHYSIOLOGY, PREVENTION, AND IT’S MANAGEMENT
Abstract: Even in situations where it wasn't necessary, antivenom research was applied to snake bite cases. In order to improve their level of understanding, primary practitioners should receive training on handling envenomation situations as well as current recommendations and references. In cases of snake bites, antivenom must be delivered according to applicable systemic and original indications.More than ten percent of cases with admitted ASV experience some sort of reaction, ranging from …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 40–46 Read article
-
Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
-
Microneedles and the paradigm shift in the field of dentistry: A Review Article
Abstract: Needle-based instruments are advancing as a promising tool for both diagnosis and treatment within the medical realm. They possess versatility, being capable of drug delivery and fluid extraction, catering to both systemic and local requirements. Unlike traditional drug delivery methods, which necessitate repeated dosing in the oral cavity due to saliva presence, there's a growing demand for delivery systems like needle-based devices that can offer sustained drug release orally. These …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 4, 2024 Read article
-
Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article