Search
229 articles for “Bioactive compound”
-
Chalcones: Beyond Bioactive Properties - Exploring Their Potential as Polymeric Materials
Abstract: Chalcones, a class of natural compounds characterized by their unique chemical structure, have garnered significant attention in recent years for their diverse pharmacological and biological activities. This review aims to comprehensively assess and summarize the latest research spanning the last five years. By synthesizing findings from a plethora of studies, this retrospective analysis elucidates the evolving landscape of chalcone research, shedding light on their therapeutic potential and biological effects. The …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 997–1003 Read article
-
The Therapeutic and Biotechnological Potential of Pogostemon benghalensis – A Comprehensive Review
Abstract: Pogostemon benghalensis is a fragrant perennial shrub belonging to the family Lamiaceae, widely distributed across tropical and subtropical regions of Asia. It has been extensively utilized in traditional and ethnomedicinal systems for the treatment of wounds, skin infections, fever, digestive disorders, inflammation, and respiratory ailments. The plant is also valued for its antiseptic, aphrodisiac, insect-repellent, and veterinary medicinal properties. Its leaves, roots, and essential oil are incorporated into herbal formulations, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 55–63 Read article
-
In Silico Assessment of Drug like Properties of Some Thiadiazole and Oxadiazole Derivatives as HDAC Inhibitors
Abstract: Purpose: To investigate in silico the drug-like properties of some thiadiazole and oxadiazole derivatives as HDAC inhibitors. Methods: We used Chemdraw Ultra 11.0 to redraw all chemical structures. Furthermore, some applications, such as Bio-Loom for Windows - version 1.5, Molinspiration Property Calculator, and ACD/I-LAB, were used to forecast the drug-like properties of thiadiazole and oxadiazole derivatives, including relative molecular mass (MW), partition coefficient log P (cLog P), number of hydrogen …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 1–13 Read article
-
Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
-
Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
-
A Comprehensive Review on Coumarin Derivatives
Abstract: Coumarins are naturally occurring compounds found in plants, fungi, and microorganisms with diverse bioactivities. They have antithrombotic, anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, and neuroprotective properties. Extracting coumarins, using methods like maceration and microwave- assisted extraction, is crucial for their applications. However, safety and toxicology are important, especially in pharmaceuticals, cosmetics, and food additives. Consuming moderate amounts of coumarin-rich foods is generally safe, but excessive intake raises concerns about hepatotoxicity and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 72–80 Read article
-
Utilization of Banana Peel Biopolymer as a Natural Coagulant for Wastewater Treatment: A Sustainable Approach to Bio-Composite Applications
Abstract: This study explores an eco-innovative approach to wastewater treatment by utilizing banana peel powder (BPP) as a sustainable, low-cost bio-coagulant. Although effective, conventional chemical coagulants like aluminum sulfate and synthetic polymers are often non-biodegradable, toxic, and economically burdensome, particularly in decentralized or low-resource settings. In contrast, BPP—an agro-waste material rich in bioactive functional groups such as hydroxyl, carboxyl, and phenolic compounds—provides a renewable and environmentally friendly alternative. To enhance its …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 106–115 Read article
-
Rauwolfia Serpentina: A Comprehensive Phytochemical Study of Its Bioactive Metabolites
Abstract: Rauwolfia Serpentina is an important medicinal plant used in Ayurveda, Unani, and folk medicine system of medicine. This plant grew as a bush in company of other plants as an evergreen structure. It is commonly known as ‘Sarpaghanda’. in Ayurvedic and Unani medicine system. It is safe and effective for the treatment of snakebites and various types of disease like malaria, breast cancer, prostate cancer, high blood pressure, insomnia, epilepsy, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 25–50 Read article
-
QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
-
Anti-Cancer Effect of Cordyceps Militaris
Abstract: Cordyceps militaris is a therapeutic fungus that has been used for traditional herbal remedies. It contains variety of bioactive elements, including cordycepin. Cordycepin (3’-deoxyadenosine), is the main compound and is believed to have anti-cancer potential. Treatment of various cancer cells with cordycepin effectively causes cell death and slows down the nature of the cancer. But yet, the underlying mechanism is not fully understood. Recent findings provide information about molecular signalling …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 1, 2023 · pp. 18–24 Read article
-
Chemical Investigation on Roots of Angelica glauca High Altitude Himalayan Herb
Abstract: The essential oil of Angelica glauca collected from Kumaun Himalayan region of India was analyzed by GC-MS. It has been found rich in sesquiterpenes (52.23%), fatty acids (17.686%), diterpenes (2.771%) apart from bioactive constituents (z)-Lingustilide (4.531%) and (z)-Butylidene phthalide (11.061%). Twenty seven compounds have been identified by comparison of their MS and retention time through literature search.
Published in Research and Reviews: A Journal of Pharmacology · Vol. 2, Issue 2, 2012 · pp. 1–4 Read article
-
Role of carbohydrates as therapeutic agents
Abstract: Carbohydrates are naturally occurring compounds essential for life, which includes sugars, starch and cellulose as well as component of bacterial cell wall1. The development of carbohydrates as therapeutics continues to gain interest, as the biological roles of these polymers are further elucidated and understood. Recent advances in the understanding of carbohydrate specific transport mechanism and the development of novel carbohydrate based bioactive may overcome many of the previous limitations of …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 1, 2019 · pp. 1–5 Read article
-
Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
-
Use of Chicken Mechanically Separated Meat to Obtain Bioactive Peptides
Abstract: Chicken meat is mainly marketed as whole or cut pieces. Some cuts as breast and thigh fillets, back, neck, wings and other bone parts result in by-products, such as mechanically separated meat (MSM). MSM is composed by a large amount of proteins, which have direct application in the production of cooked sausages and mortadella, in addition, protein hydrolysates in order to obtain bioactive peptides. These peptides have functional properties such …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 11, Issue 1, 2022 · pp. 20–37 Read article
-
Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
-
Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article
-
Grape Seed Extract: Potent Chemoprotective Agent: Phytochemical Analysis and GC-MS Study
Abstract: Plant extracts or secondary metabolites have served as antioxidants in phytotherapeutic medicines to protect against various diseases for centuries. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables and roots that have defence mechanism and protect from various diseases. Phytochemicals are primary and secondary compounds. Chlorophyll, proteins and common sugars are included in primary constituents and secondary compounds include terpenoids, alkaloids, quinines, flavonoids, sterols, saponins, tannins and phenolic compounds. …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 3, 2016 · pp. 30–39 Read article
-
Promising Antimicrobial Compounds from an Endophytic Fungus Penicillium daleae EF 4 Isolated from the Seaweed Enteromorpha flexuosa Linn.
Abstract: AbstractThe present aim of the study is to isolate the endophytic fungi from various seaweeds and to screen their bioactivity, to analyze the β-lactamase inactivator and to evaluate the interactions between the crude extract of Endophytic fungi Penicillium daleae EF 4 and two antibiotics (penicillin G and tetracycline), against some antibiotic resistant bacterial strains. Seaweeds collected from various places of Bay of Bengal coast was subjected to Endophytic fungal isolation. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 26–39 Read article
-
Unlocking The Bioactivity Potential: Molecular Insights and Predictions of Salen, Salophen, Allicin, Curcumin, and Piperine
Abstract: In this work, the prediction of the biological activity of several significant molecules, including salen, salophen, allicin, curcumin, and piperine, are discussed. Using Molinspiration software, the molecular properties of these compounds were calculated. These molecules are highly significant due to their extensive potential in medical applications. Salen and salophen, for instance, play crucial roles in cancer chemotherapy and act as inhibitors of angiogenesis. Curcumin is renowned for its antioxidant properties, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 14–21 Read article
-
Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article